Evaluation of human chorionic gonadotropin stimulation tests in prepubertal and early pubertal boys.

Abstract:

:We evaluated the diagnostic significance of single versus repeated human chorionic gonadotropin (hCG) stimulation of testicular steroidogenesis in 25 boys (10 prepubertal group A; 15 early pubertal, group B) with suspected hypogonadism. All subjects received a single injection of hCG (5000 U/1.7 m2) and 1 month later, three repeated injections of 1500 U, one each on alternate days. In 19 out of the 25 boys, testosterone increased normally in both tests: from 20 +/- 6 to 156 +/- 82 ng/dl and from 107 +/- 105 to 615 +/- 293 ng/dl, following a single hCG injection, and from 30 +/- 19 to 439 +/- 298 ng/dl and from 94 +/- 55 to 826 +/- 272 ng/dl, following repeated injections in groups A and B, respectively. The difference between the tests was significant (P < 0.01). Conclusion. Single hCG injection used as a screening test in the evaluation of hypogonadism is conclusive when positive. Only when the initial test is negative may a repeated test help establish the diagnosis.

journal_name

Eur J Pediatr

authors

Kauschansky A,Frydman M,Nussinovitch M,Varsano I

doi

10.1007/BF01957499

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

890-2

issue

11

eissn

0340-6199

issn

1432-1076

journal_volume

154

pub_type

临床试验,杂志文章
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  • The effect of vitamin K supplementation on biochemical markers of bone formation in children and adolescents with cystic fibrosis.

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    更新日期:2006-08-01 00:00:00

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  • Recent progress in clinical and basic pertussis research.

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  • Anomalous inheritance in a kindred with split hand, split foot malformation.

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    pub_type: 杂志文章

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    更新日期:1988-02-01 00:00:00

  • A previously healthy 15-year-old girl with high fever and progressive dyspnoea.

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    journal_title:European journal of pediatrics

    pub_type: 杂志文章

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  • Elective cesarean delivery at term and the long-term risk for respiratory morbidity of the offspring.

    abstract::Maternal morbidity is associated with cesarean deliveries. However, new evidence suggests that short- and long-term neonatal morbidity is also associated. This includes respiratory morbidity with conflicting results. To determine whether mode of delivery has an impact on the long-term risk for respiratory morbidity in...

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    pub_type: 杂志文章

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  • The influence of mutations of enzyme activity and phenylalanine tolerance in phenylalanine hydroxylase deficiency.

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    journal_title:European journal of pediatrics

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    doi:10.1007/pl00014253

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    更新日期:1996-07-01 00:00:00

  • Thyroid function testing in neonates born to women with hypothyroidism.

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    journal_title:European journal of pediatrics

    pub_type: 杂志文章

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  • Congenital diaphragmatic eventration and hernia sac compared to CDH with true defects: a retrospective cohort study.

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    journal_title:European journal of pediatrics

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  • Ipratropium bromide for symptomatic preterm infants.

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    journal_title:European journal of pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

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  • Familial hemophagocytic lymphohistiocytosis.

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    pub_type: 杂志文章,评审

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    更新日期:1983-06-01 00:00:00

  • HLA-haploidentical bone marrow transplantation in three infants with adenosine deaminase deficiency: stable immunological reconstitution and reversal of skeletal abnormalities.

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    pub_type: 杂志文章

    doi:10.1007/BF01995857

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  • Independent risk factors for recurrence of apparent life-threatening events in infants.

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    authors: Ueda R,Nomura O,Maekawa T,Sakai H,Nakagawa S,Ishiguro A

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  • Asymmetry in children with cerebral palsy and oral structure.

    abstract::Twenty-six children with cerebral palsy were examined with respect to structural asymmetry of the mouth. In 19 children there were clear cut correlations between symmetry/asymmetry of voluntary function and the oral findings. Patients with symmetrical patterns of movements had symmetrical dentition, while in those wit...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF00441639

    authors: Haberfellner H,Richter M

    更新日期:1980-12-01 00:00:00

  • Epidemiology and clinical features of respiratory adenoviral infections in children.

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    journal_title:European journal of pediatrics

    pub_type: 杂志文章

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    authors: Sun Q,Jiang W,Chen Z,Huang L,Wang Y,Huang F,Ji W,Zhang X,Shao X,Yan Y

    更新日期:2014-04-01 00:00:00

  • Evaluation of the indications for early exchange transfusion in rhesus haemolytic disease during phototherapy.

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    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF00444752

    authors: Ebbesen F

    更新日期:1980-01-01 00:00:00

  • The "price-tag" of foot health in infancy and early childhood: a cross sectional survey of UK parents.

    abstract::Children's feet are complex structures and strategies for supporting good foot health throughout childhood can be challenging. Greater awareness of the contemporary factors influencing decisions, such as footwear purchases, is needed to inform health narratives which are more closely aligned to parents' attitude and b...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s00431-020-03920-0

    authors: Hodgson L,Hodges M,Williams AE,Nester CJ,Morrison SC

    更新日期:2021-01-15 00:00:00

  • Neonatal manifestation of multiple sulfatase deficiency.

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  • Hip effusion in nephrotic syndrome mimicking septic arthritis.

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    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02072499

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    更新日期:1993-02-01 00:00:00

  • Bone marrow hypoplasia in anorexia nervosa.

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    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF00452416

    authors: Lampert F,Lau B

    更新日期:1976-12-09 00:00:00

  • Factors associated with proceeding to surgical intervention and recurrence of primary spontaneous pneumothorax in adolescent patients.

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    pub_type: 杂志文章

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    更新日期:2014-11-01 00:00:00

  • Perinatal COVID-19: review of current evidence and practical approach towards prevention and management.

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    pub_type: 杂志文章,评审

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    更新日期:2020-11-12 00:00:00

  • Intellectual capacity of subjects exposed to methimazole or propylthiouracil in utero.

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    journal_title:European journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF01957719

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    更新日期:1992-08-01 00:00:00

  • Cord blood alpha-fetoprotein concentrations in term newborns of smoking mothers.

    abstract:UNLABELLED:To investigate the toxic effect of tobacco smoke on the fetus, we measured in cord blood the concentrations of alpha-fetoprotein (AFP), the principal serum protein in early ontogenic development, and erythropoietin (EPO), as an index of chronic fetal hypoxia. A total of 103 consecutively enrolled term newbor...

    journal_title:European journal of pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1007/s004310051152

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    更新日期:1999-07-01 00:00:00

  • The accuracy of voiding urosonography in detecting vesico-ureteral reflux: a summary of existing data.

    abstract:UNLABELLED:The primary objective of this review was to assess the diagnostic accuracy of voiding urosonography (VUS) in detecting reflux (VUR). As a secondary objective, the reported technical suggestions and diagnostic mistakes were shown to improve the examination protocol and provide the most accurate results. Using...

    journal_title:European journal of pediatrics

    pub_type: 杂志文章

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    更新日期:2002-07-01 00:00:00

  • Parameters affecting length of stay in a pediatric emergency department: a retrospective observational study.

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    journal_title:European journal of pediatrics

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  • Fetomaternal haemorrhage and prenatal intracranial bleeding: two more causes of blueberry muffin baby.

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    journal_title:European journal of pediatrics

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    更新日期:1998-11-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:1994-01-01 00:00:00