Abstract:
UNLABELLED:Blueberry muffin lesions are associated with prenatal infections, severe and chronic anemia and neoplastic infiltrative diseases. In the first two instances they represent postnatal re-expression of cutaneous haematopoiesis, in the latter they are cutaneous localizations of a neoplastic disease. Chronic prenatal anaemia leading to blueberry muffin lesions in the neonate has been reported in association with severe haemolytic anaemia such as congenital spherocytosis, Rhesus haemolytic disease and ABO incompatibility, or in anaemia caused by twin-to-twin transfusion. We present two more causes of prenatal anaemia leading to blueberry muffin lesions: chronic fetomaternal haemorrhage and severe intracranial bleeding. CONCLUSION:In any blueberry muffin baby with profound anaemia, chronic fetomaternal haemorrhage and severe internal bleeding should be included in the differential diagnosis. Skin biopsy must be performed to rule out neoplastic infiltrative diseases.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Smets K,Van Aken Sdoi
10.1007/s004310050970subject
Has Abstractpub_date
1998-11-01 00:00:00pages
932-4issue
11eissn
0340-6199issn
1432-1076journal_volume
157pub_type
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