Severe tick-borne encephalitis following passive immunization.

Abstract:

UNLABELLED:We report on a 5-year-old girl with an unusually severe course of tick-borne encephalitis following passive immunization with specific hyperimmune globulin after a tick bite in an endemic area. Serial investigations of the CSF revealed intrathecal production of specific antibodies paralleled by increasing numbers of B-cells after initial T-cell pleocytosis. Focal central lesions were evident on MRI. CONCLUSION:The severity of the presented case questions the benefit of passive immunization and rather justifies consideration of vaccine recommendation to residents and travellers to areas endemic for tick-borne encephalitis virus.

journal_name

Eur J Pediatr

authors

Waldvogel K,Bossart W,Huisman T,Boltshauser E,Nadal D

doi

10.1007/BF02002905

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

775-9

issue

9

eissn

0340-6199

issn

1432-1076

journal_volume

155

pub_type

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