Abstract:
:Side-effects are commonly manifested during intravesical Bacillus Calmette-Guérin (BCG) immunotherapy of superficial bladder cancer. This often causes delays or interruptions of the instillations and consequently reduces the efficacy of treatment. Treatment strategies aimed at reducing the side-effects of BCG immunotherapy while maintaining efficacy are currently being considered in the search for an optimal treatment regimen. The following two approaches to BCG immunotherapy were investigated at the Department of Urology of Padova University by specific Phase II and III trials designed to evaluate the possibility of reducing BCG-related side-effects without compromising therapeutic efficacy: (1) by reducing the dose of BCG per instillation 'low-dose' regimen, (2) by delaying the interval of the instillations 'slow-rate' regimen.
journal_name
Eur Uroljournal_title
European urologyauthors
Bassi P,Spinadin R,Carando R,Balta G,Pagano Fdoi
10.1159/000052380keywords:
subject
Has Abstractpub_date
2000-01-01 00:00:00pages
31-2eissn
0302-2838issn
1873-7560pii
52380journal_volume
37 Suppl 1pub_type
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