Abstract：
:Experiments were conducted to study the functional implication of a mannose-binding glycoprotein found in the day 4 post coital (p.c.) rat uterus, using a mono-specific polyclonal antibody raised against the glycoprotein. Western Blot and immunohistochemical techniques were employed to study the distribution of the glycoprotein, and the results suggest that this glycoprotein is present only in the day 4 p.c. uterus and is specifically localized in the stromal cells. Administration of anti-UA (Uterine Agglutinin) antiserum against the glycoprotein into the day 4 p.c. uterine lumen inhibits carrying of embryo to term. The antiserum is not embryo toxic. After in vivo in utero intra-luminal administration of anti-UA antiserum in day 4 p.c. rat the antiserum has been specifically localized in the uterine stroma by immunohistochemistry. After intravenous injection, the glycoprotein is cleared mainly through the kidney and liver. The possible role of this glycoprotein in the implantation process in rats has been discussed. From the data it is evident that UA may not be directly involved in sugar-sugar interactions with embryo since it is not present in any significant amount in pregnant uterus from day 5 onwards. Since other experiments show that UA does have some role to play in early pregnancy, UA probably acts through some other factor, and preliminary studies suggest that this factor maybe TGF-beta3.
journal_name
Mol Cell Biochemjournal_title
Molecular and cellular biochemistryauthors
Mehta M,Chowdhury Mdoi
10.1023/a:1006901206170keywords:
subject
Has Abstractpub_date
1999-05-01 00:00:00pages
65-75issue
1-2eissn
0300-8177issn
1573-4919journal_volume
195pub_type
杂志文章abstract：:The uptake of glucose and gluconate is under inductive control in Pseudomonas putida. Glucose, gluconate, and 2-ketogluconate were each good nutritional inducers of these transport abilities. Glucose and gluconate uptake obeyed saturation kinetics: the apparent Km for glucose was 6 mM and that for gluconate was 0.5 mM...
journal_title：Molecular and cellular biochemistry
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更新日期：1975-04-30 00:00:00
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journal_title：Molecular and cellular biochemistry
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doi：10.1007/BF01076569
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更新日期：2001-06-01 00:00:00
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journal_title：Molecular and cellular biochemistry
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更新日期：1998-10-01 00:00:00
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journal_title：Molecular and cellular biochemistry
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doi：10.1007/BF00223559
更新日期：1990-04-18 00:00:00
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更新日期：2016-04-01 00:00:00
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journal_title：Molecular and cellular biochemistry
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doi：
更新日期：2002-05-01 00:00:00
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journal_title：Molecular and cellular biochemistry
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更新日期：1995-03-09 00:00:00
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更新日期：2007-06-01 00:00:00
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更新日期：2012-01-01 00:00:00
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journal_title：Molecular and cellular biochemistry
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更新日期：1982-04-16 00:00:00
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journal_title：Molecular and cellular biochemistry
pub_type： 杂志文章,评审
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abstract：:To understand the hypocholesterolemic activity of green tea, our in vitro studies screened the relative efficacy of two structurally distinct green tea catechins, epicatechin (EC) and epigallocatechin gallate (EGCG), on apolipoprotein B-100 (apoB) and lipid production using a well established human hepatoma cell-line,...
journal_title：Molecular and cellular biochemistry
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更新日期：2002-01-01 00:00:00
abstract：:Ribosomal 60S subunits active in polyphenylalanine synthesis can be reconstituted from core particles lacking 20-40% of the total protein. These core particles were obtained by treatment of yeast 60S subunits with dimethylmaleic anhydride, a reagent for protein amino groups. Upon reconstitution a complementary amount ...
journal_title：Molecular and cellular biochemistry
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更新日期：1985-02-01 00:00:00
