Anticarcinogenic effect of Nymphaea alba against oxidative damage, hyperproliferative response and renal carcinogenesis in Wistar rats.

abstract：:Inadequate migration and invasion of the trophoblast cells during embryo implantation is one of the reasons for pregnancy-related complications such as intrauterine growth restriction and preeclampsia. In the present study, relevance of WNT ligands and integrins associated with hepatocyte growth factor (HGF)-mediated ...

journal_title：Molecular and cellular biochemistry

authors： Chaudhary P,Malhotra SS,Babu GS,Sobti RC,Gupta SK

更新日期：2019-03-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF)-D is a crucial mediator of angiogenesis. Following myocardial infarction (MI), cardiac VEGF-D and VEGF receptor (VEGFR)-3 are significantly upregulated. In addition to endothelial cells, myofibroblasts at the site of MI highly express VEGFR-3, implicating the involvement of VE...

journal_title：Molecular and cellular biochemistry

authors： Zhao T,Zhao W,Meng W,Liu C,Chen Y,Bhattacharya SK,Sun Y

更新日期：2016-02-01 00:00:00

abstract：:Despite the recognized role of bradykinin (BK)-induced calcium and chloride conductance in regulating salt transport in the kidney, the signaling pathway involved has not been well examined. Patch clamp of murine proximal tubule (TKPTS) cells revealed that BK (10 nM) produced an increase in an outwardly rectifying cur...

journal_title：Molecular and cellular biochemistry

authors： Tiwari MM,Stimers JR,Mayeux PR

更新日期：2007-03-01 00:00:00

abstract：:This paper reviews the model of the control of mitochondrial substrate oxidation by Ca2+ ions. The mechanism is the activation by Ca2+ of four mitochondrial dehydrogenases, viz. glycerol 3-phosphate dehydrogenase, the pyruvate dehydrogenase multienzyme complex (PDH), NAD-linked isocitrate dehydrogenase (NAD-IDH) and 2...

journal_title：Molecular and cellular biochemistry

authors： Hansford RG,Zorov D

更新日期：1998-07-01 00:00:00

abstract：:Understanding transmembrane signalling process is one of the major challenge of the decade. In most tissues, since Fisher and Krebs's discovery in the 1950's, protein phosphorylation has been widely recognized as a key event of this cellular function. Indeed, binding of hormones or neurotransmitters to specific membra...

journal_title：Molecular and cellular biochemistry

authors： Pucéat M,Vassort G

更新日期：1996-04-12 00:00:00

abstract：:Pluripotent stem cells within the adipose stromal compartment, termed adipose-derived stromal cells (ASCs), have the potential to differentiate into a variety of cell lineages both in vitro and in vivo. Imaging with expression of exogenous or endogenous green fluorescent protein (GFP) reporters facilitates the detaile...

journal_title：Molecular and cellular biochemistry

authors： Lin Y,Tian W,Chen X,Yan Z,Li Z,Qiao J,Liu L,Tang W,Zheng X

更新日期：2005-09-01 00:00:00

abstract：:Signal transduction pathways control various biological processes in cells leading to distinct cellular functions. Protein-protein interactions and post-translational modifications are the physiological events that occur in signaling pathway. p38 MAPK are known to be involved in regulating wide range of cellular proce...

journal_title：Molecular and cellular biochemistry

authors： Rini J,Anbalagan M

更新日期：2017-11-01 00:00:00

abstract：:Liver-X-Receptor alpha (LXR-alpha) that belongs to nuclear receptor/transcriptional factor family has been recognized to play crucial role in the regulation of lipid metabolism and inflammation. Consequently, the present study was addressed to explore the functional genomics of LXR-alpha within human blood immunomodul...

journal_title：Molecular and cellular biochemistry

authors： Kaul D,Gautam A,Sikand K

更新日期：2006-11-01 00:00:00

abstract：:Twenty-six days of fat deficiency brought about a decrease of linoleic and an increase of oleic acid in rough endoplasmic reticulum (RER) of guinea pig liver. Arachidonic acid was only slightly decreased in some phospholipids whereas eicose-5,8,11-trienoic acid was not enhanced except in phosphatidyl-inositol. All the...

journal_title：Molecular and cellular biochemistry

authors： Soulages JL,Brenner RR

更新日期：1987-12-01 00:00:00

abstract：:In this study, we examined changes in the biochemical and inotropic events of the alpha(1)-adrenoceptor signaling pathway in hypothyroid rat hearts. Hypothyroidism was induced by treating experimental animals with 0.05% 6-n-propyl-2-thiouracil (PTU) in drinking water for 7 weeks. A significant decrease of beta- and an...

journal_title：Molecular and cellular biochemistry

authors： Jalali S,Durston M,Panagia V,Mesaeli N

更新日期：2006-02-01 00:00:00

abstract：:Transmission of extra cellular signals across biological membranes results in the generation of lipid metabolites which in turn influence specific cellular events such as cell growth or differentiation. Many of these lipid messengers can activate protein kinase C (PKC) isozymes of which one function is to perpetuate t...

journal_title：Molecular and cellular biochemistry

authors： Sista P,Edmiston S,Darges JW,Robinson S,Burns DJ

更新日期：1994-12-21 00:00:00

abstract：:Fluoroquinolone antibiotics provide broad-spectrum coverage for a number of infectious diseases, including respiratory as well as urinary tract infections. One of the important adverse effects of these drugs is phototoxicity which introduces a serious limitation to their use. To gain insight the molecular mechanisms u...

journal_title：Molecular and cellular biochemistry

authors： Beberok A,Wrześniok D,Otręba M,Miliński M,Rok J,Buszman E

更新日期：2015-03-01 00:00:00

abstract：:Doxorubicin (DOX) is a DNA topoisomerase II inhibitor widely used in anticancer treatment, however, it can lead to irreversible cardiac damage with severe debilitation. TBP-binding associated factor 1 (TAF1) is increased in DOX damaged hearts in vivo and in cardiomyocytes in vitro. To identify the functional role for ...

journal_title：Molecular and cellular biochemistry

authors： Servant N,Marcantonio D,Th'ng JP,Chalifour LE

更新日期：2004-04-01 00:00:00

abstract：:Hypermethylation of promoter CpG islands represents an alternative mechanism to inactivate tumor suppressor genes. This study was to detect promoter methylation status and mRNA expression levels of ARRDC3, ELP3, GATA5, and PAX6, and to explore the association between methylation and expression in invasive ductal carci...

journal_title：Molecular and cellular biochemistry

authors： Wang D,Yang PN,Chen J,Zhou XY,Liu QJ,Li HJ,Li CL

更新日期：2014-11-01 00:00:00

abstract：:A liver cytochrome P-450 isozyme has been purified to homogeneity from protein-energy malnourished rats induced with beta-naphthoflavone (beta-NF). The purification steps included chromatography on DEAE-Sephadex-A-25, DEAE-cellulose (DE-53), hydroxylapatite (HA) and carboxymethyl-sephadex (CM) columns. The reduced car...

journal_title：Molecular and cellular biochemistry

authors： Gil L,Vasquez H,Orellana M,Selkirk J,Wold F,Strobel H

更新日期：1988-01-01 00:00:00

abstract：:Etomoxir, an inhibitor of mitochondrial carnitine palmitoyltransferase-1, is known to attenuate the changes in myosin isoforms and sarcoplasmic reticular function that occur in diabetic rat hearts. In the present study, we tested the hypothesis that etomoxir also prevents the diabetes-induced depression of sarcolemmal...

journal_title：Molecular and cellular biochemistry

authors： Kato K,Lukas A,Chapman DC,Rupp H,Dhalla NS

更新日期：2002-03-01 00:00:00

abstract：:As a m6A methylation modifier, METTL3 is functionally involved in various biological processes. Nevertheless, the role of METTL3 in osteogenesis is not determined up to date. In the current study, METTL3 is identified as a crucial regulator in the progression of osteogenic differentiation. Loss of METTL3 significantly...

journal_title：Molecular and cellular biochemistry

authors： Yu J,Shen L,Liu Y,Ming H,Zhu X,Chu M,Lin J

更新日期：2020-01-01 00:00:00

abstract：:The purpose of this investigation was to determine whether fibronectin preparations from both chicken plasma and cell surface of fibroblasts can promote phagocytosis of gelatin-coated latex particles. Chicken plasma fibronectin was isolated (a) by ammonium sulfate fractionation, chromatography on Sepharose-4B followed...

journal_title：Molecular and cellular biochemistry

authors： Marquette D,Molnar J,Yamada K,Schlesinger D,Darby S,Van Alten P

更新日期：1981-05-26 00:00:00

abstract：:The genome sequence of Mycobacterium tuberculosis revealed the presence of several hydrolases involved in lipid metabolism including the members of Lip gene family. Rv0646c (LipG) is one of them. It is annotated as putative esterase/lipase because of the presence of consensus sequence 'GXSXG.' The gene was cloned, exp...

journal_title：Molecular and cellular biochemistry

authors： Rastogi R,Kumar A,Kaur J,Saini V,Kaur J,Bhatnagar A

更新日期：2018-10-01 00:00:00

abstract：:Antecedent studies have suggested that lipid composition and fluidity of cellular membranes of various organs are altered in response to thyroid hormone status. To date, the effects of thyroid hormone status on these parameters have not been examined in rat renal apical membrane in regard to sodium-dependent phosphate...

journal_title：Molecular and cellular biochemistry

authors： Prasad R,Kumar V

更新日期：2005-01-01 00:00:00

abstract：:Free fatty acids (FFA)-induced proliferation and apoptosis was studied in human umbilical vein endothelial cells (HUVECs). A recombinant adenovirus containing a RNAi cassette targeting the GSK-3beta gene was produced and its silencing effect on GSK-3beta gene was detected by Western blot analysis and immunohistochemis...

journal_title：Molecular and cellular biochemistry

authors： Zhu P,Chen G,You T,Yao J,Jiang Q,Lin X,Shen X,Qiao Y,Lin L

更新日期：2010-05-01 00:00:00

abstract：:Calcineurin inhibitors are used in immunosuppressive therapy applied after transplantation, but they are associated with major metabolic side effects including the development of new onset diabetes. Previously, we have shown that the calcineurin inhibiting drugs tacrolimus and cyclosporin A reduce adipocyte and myocyt...

journal_title：Molecular and cellular biochemistry

authors： Fonseca ACRG,Carvalho E,Eriksson JW,Pereira MJ

更新日期：2018-08-01 00:00:00

abstract：:Cell proliferation and migration are crucial in many physiological processes including development, cancer, tissue repair, and wound healing. Cell migration is regulated by several signaling molecules. Identification of genes related to cell migration is required to understand molecular mechanism of non-healing chroni...

journal_title：Molecular and cellular biochemistry

authors： Demirci S,Doğan A,Apdik H,Tuysuz EC,Gulluoglu S,Bayrak OF,Şahin F

更新日期：2018-01-01 00:00:00

abstract：:The rat uterine secretory enzyme glycerylphosphorylcholine (GPC) diesterase (EC 3.1.4.2) had been purified and characterized previously with respect to its mol. wt., size, amino acid, carbohydrate composition and estrogen inducible properties. This enzyme is observed to have exclusive specificity for GPC and exhibits ...

journal_title：Molecular and cellular biochemistry

authors： Mitra J,Chowdhury M

更新日期：1994-10-26 00:00:00

abstract：:A calcium activated photoprotein, termed mnemiopsin, which emits bioluminescence upon the addition of calcium ion, has been isolated from the Ctenophore, Memiopsis leidyi, and purified by hollow fiber techniques. The system is similar to aequorin, from the jellyfish Aequorea, except that mnemiopsin can be light-inacti...

journal_title：Molecular and cellular biochemistry

authors： Girsch SJ,Hastings JW

更新日期：1978-04-11 00:00:00

abstract：:Thioredoxin (Trx) is a small ubiquitous protein, which has been shown to be involved in redox-dependent cellular functions. In this article, we demonstrate that the increased level of Trx induces AP-1 DNA binding in a redox-dependent manner by activating JNK subgroup of MAPKs. The majority of AP-1 DNA binding complex ...

journal_title：Molecular and cellular biochemistry

authors： Das KC,Muniyappa H

更新日期：2010-04-01 00:00:00

abstract：:Bipolar disorder (BD) is a psychiatric disorder characterized by alternating episodes of mania and depression. The intracerebroventricular (i.c.v) administration of ouabain (a Na(+)/K(+)-ATPase inhibitor) in rats has been used as an animal model of mania, because present face, construct and predictive validities. Seve...

journal_title：Molecular and cellular biochemistry

authors： Freitas TP,Rezin GT,Gonçalves CL,Jeremias GC,Gomes LM,Scaini G,Teodorak BP,Valvassori SS,Quevedo J,Streck EL

更新日期：2010-08-01 00:00:00

abstract：:The present study is to investigate the effect and mechanism of action of interleukin (IL)-17A and its receptor IL-17RA on non-small cell lung cancer (NSCLC). A total of 139 NSCLC patients were included in the study. NSCLC tissues and tumor-adjacent tissues were collected from the patients. Human NSCLC cell lines H157...

journal_title：Molecular and cellular biochemistry

authors： Wu Z,He D,Zhao S,Wang H

更新日期：2019-05-01 00:00:00

abstract：:The interaction between dipalmitoyl lecithin and egg lecithin with insulin was studied in a non-aqueous solvent such as dioxane-chloroform (1:1) by dielectric constant measurements and absorption spectra. The electrostatic character of the interaction results from the dielectric measurements and the effect of an exter...

journal_title：Molecular and cellular biochemistry

authors： Galzigna L,Garbin L,Rigoni F,Siliprandi N

更新日期：1980-03-20 00:00:00

abstract：:The results of our previous studies demonstrated that acute streptozotocin-induced diabetes in rats evoked a decrease in skin collagen content with little effect on glycosaminoglycans (GAG) content. In our present study we employed the model of chronic diabetes in order to check its effect on skin GAG content. It was ...

journal_title：Molecular and cellular biochemistry

authors： Cechowska-Pasko M,Pałka J,Bańkowski E

更新日期：1996-01-12 00:00:00