Abstract:
:Recent reports have suggested that variability in the alpha2-macroglobulin gene is a genetic risk factor for Alzheimer's disease. Here we have both tested a common polymorphism in the gene (I1000V) for association with the disease in a four-site case control study design, and tested the locus for linkage in a large series of sibpairs afflicted with late onset disease. Our results fail to show an association between this polymorphism and disease.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Wavrant-DeVrièze F,Rudrasingham V,Lambert JC,Chakraverty S,Kehoe P,Crook R,Amouyel P,Wu W,Holmans P,Rice F,Pérez-Tur J,Frigard B,Morris JC,Carty S,Cottel D,Tunstall N,Lovestone S,Petersen RC,Chartier-Harlin MC,Goatedoi
10.1016/s0304-3940(99)00035-xkeywords:
subject
Has Abstractpub_date
1999-03-05 00:00:00pages
137-9issue
2eissn
0304-3940issn
1872-7972pii
S030439409900035Xjournal_volume
262pub_type
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2005.01.035
更新日期:2005-05-20 00:00:00
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2004-09-23 00:00:00
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journal_title:Neuroscience letters
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更新日期:2013-06-17 00:00:00