Abstract：
:The phenomenon of chromosome, or genomic, imprinting indicates the relevance of parental origin in determining functional differences between alleles, homologous chromosomes, or haploid sets. In mealybug males (Homoptera, Coccoidea), the haploid set of paternal origin undergoes heterochromatization at midcleavage and remains so in most of the tissues. This different behavior of the two haploid sets, which depends on their parental origin, represents one of the most striking examples of chromosome imprinting. In mammals, DNA methylation has been postulated as a possible molecular mechanism to differentially imprint DNA sequences during spermatogenesis or oogenesis. In the present article we addressed the role of DNA methylation in the imprinting of whole haploid sets as it occurs in Coccids. We investigated the DNA methylation patterns at both the molecular and chromosomal level in the mealybug Planococcus citri. We found that in both males and females the paternally derived haploid set is hypomethylated with respect to the maternally derived one. Therefore, in males, it is the paternally derived hypomethylated haploid set that is heterochromatized. Our data suggest that the two haploid sets are imprinted by parent-of-origin-specific DNA methylation with no correlation with the known gene-silencing properties of this base modification.
journal_name
Geneticsjournal_title
Geneticsauthors
Bongiorni S,Cintio O,Prantera Gkeywords:
subject
Has Abstractpub_date
1999-04-01 00:00:00pages
1471-8issue
4eissn
0016-6731issn
1943-2631journal_volume
151pub_type
杂志文章相关文献
GENETICS文献大全abstract：:Restriction fragment length polymorphisms in mitochondrial DNA (mtDNA) were used to reconstruct evolutionary relationships of conspecific populations in four species of freshwater fish-Amia calva, Lepomis punctatus, L. gulosus, and L. microlophus. A suite of 14-17 endonucleases was employed to assay mtDNAs from 305 sp...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1986-08-01 00:00:00
abstract：:We examined the effect of a single variant repeat on the stability of a 51-base pair (bp) microsatellite (poly GT). We found that the insertion stabilizes the microsatellite about fivefold in wild-type strains. The stabilizing effect of the variant base was also observed in strains with mutations in the DNA mismatch r...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
abstract：:The agouti locus on mouse chromosome 2 encodes a secreted cysteine-rich protein of 131 amino acids that acts as a molecular switch to instruct the melanocyte to make either yellow pigment (phaeomelanin) or black pigment (eumelanin). Mutations that up-regulate agouti expression are dominant to those causing decreased e...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1995-05-01 00:00:00
abstract：:Sequence divergence among the mitochondrial (mt) DNA of nine Lycopersicon and two closely related Solanum species was estimated using the shared fragment method. A portion of each mt genome was highlighted by probing total DNA with a series of plasmid clones containing mt-specific DNA fragments from Lycopersicon penne...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：:Regulatory networks provide control over complex cell behavior in all kingdoms of life. Here we describe a statistical model, based on representing proteins as collections of domains or motifs, which predicts unknown molecular interactions within these biological networks. Using known protein-protein interactions of S...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：2001-11-01 00:00:00
abstract：:Studies of multifactorial inheritance in man have ignored nonadditive gene action or attributed it entirely to dominance. Reanalyses of dermatoglyphic data on monozygotic and dizygotic twins, siblings and parents and offspring suggest that a substantial proportion of variation in total finger pattern intensity is due ...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1984-04-01 00:00:00
abstract：:Estimating the fixation probability of a beneficial mutation has a rich history in theoretical population genetics. Typically, to attain mathematical tractability, we assume that generation times are fixed, while the number of offspring per individual is stochastic. However, fixation probabilities are extremely sensit...
journal_title：Genetics
pub_type： 杂志文章
doi：10.1534/genetics.107.072009
更新日期：2007-07-01 00:00:00
abstract：:A consensus map for loblolly pine (Pinus taeda L.) was constructed from the integration of linkage data from two unrelated three-generation outbred pedigrees. The progeny segregation data from restriction fragment length polymorphism, random amplified polymorphic DNA, and isozyme genetic markers from each pedigree wer...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:To understand the role of Los1p in pre-tRNA splicing, we sought los1 multicopy suppressors. We found SOL1 that suppresses both point and null LOS1 mutations. Since, when fused to the Ga14p DNA-binding domain, Los1p activates transcription, we tested whether Los1p regulates SOL1. We found that las1 mutants have deplete...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:High baselines of transcription factor activities represent fundamental obstacles to regulated signaling. Here we show that in Drosophila, quenching of basal activator protein 1 (AP-1) transcription factor activity serves as a prerequisite to its tight spatial and temporal control by the JNK (Jun N-terminal kinase) si...
journal_title：Genetics
pub_type： 杂志文章
doi：10.1534/genetics.107.086298
更新日期：2008-04-01 00:00:00
abstract：:We present methods for estimating the parameters of inheritance and selection that appear in a quantitative genetic model for the evolution growth trajectories and other "infinite-dimensional" traits that we recently introduced. Two methods for estimating the additive genetic covariance function are developed, a "full...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:Genes at the SerH locus of the ciliated protist Tetrahymena thermophila specify the major (H) surface protein on cells grown at 20-36 degrees. Alternative proteins L, T, S and I are expressed under different conditions of temperature and culture media. Mutants unable to express SerH genes were examined for expression ...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Stem cells have a fascinating biology and offer great prospects for therapeutic applications, stimulating intense research on what controls their properties and behavior. Although there have been significant advances in our understanding of how local microenvironments, or niches, control the maintenance and activity o...
journal_title：Genetics
pub_type： 杂志文章,评审
doi：10.1534/genetics.108.098244
更新日期：2008-12-01 00:00:00
abstract：:Microsatellites are tandemly repeated short DNA sequences that are favored as molecular-genetic markers due to their high polymorphism index. Plant genomes characterized to date exhibit taxon-specific differences in frequency, genomic location, and motif structure of microsatellites, indicating that extant microsatell...
journal_title：Genetics
pub_type： 杂志文章
doi：10.1534/genetics.105.054791
更新日期：2006-04-01 00:00:00
abstract：:A gene encoding a Ustilago maydis Rad51 orthologue has been isolated, rad51-1, a mutant constructed by disrupting the gene, was as sensitive to killing by ultraviolet light and gamma radiation as the rec2-1 mutant and slightly more sensitive to killing by methyl methanesulfonate. There was no suppression of killing by...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：:Phosphatidylinositol catabolism in Saccharomyces cerevisiae cells cultured in media containing inositol results in the release of glycerophosphoinositol (GroPIns) into the medium. As the extracellular concentration of inositol decreases with growth, the released GroPIns is transported back into the cell. Exploiting th...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：:Clinal variation is common for enzymes in the glycolytic pathway for Drosophila melanogaster and is generally accepted as an adaptive response to different climates. Although the enzyme phosphoglucomutase (PGM) possesses several allozyme polymorphisms, it is unique in that it had been reported to show no clinal variat...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：:Much of the material taken into cells by endocytosis is rapidly returned to the plasma membrane by the endocytic recycling pathway. Although recycling is vital for the correct localization of cell membrane receptors and lipids, the molecular mechanisms that regulate recycling are only partially understood. Here we sho...
journal_title：Genetics
pub_type： 杂志文章
doi：10.1534/genetics.108.087247
更新日期：2008-05-01 00:00:00
abstract：:On the basis of interallelic recombination frequencies measured in diallelic crosses of the 5 amylose-extender alleles in maize, ae, B1, B3, M2 and i1, it was possible to construct a unique linear genetic map ordering all 5 alleles within the locus. The reciprocal diallelic crosses each gave comparable frequency estim...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1972-04-01 00:00:00
abstract：:Laterality is believed to have genetic components, as has been deduced from family studies in humans and responses to artificial selection in mice, but these genetic components are unknown and the underlying physiological mechanisms are still a subject of dispute. We measured direction of laterality (preferential use ...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:RNA transcribed from the Saccharomyces cerevisiae retrotransposon Ty1 accumulates to a high level in mitotically growing haploid cells, yet transposition occurs at very low frequencies. The product of reverse transcription is a linear double-stranded DNA molecule that reenters the genome by either Ty1-integrase-mediat...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：2000-02-01 00:00:00
abstract：:Despite its importance to agriculture, the genetic basis of heterosis is still not well understood. The main competing hypotheses include dominance, overdominance, and epistasis. NC design III is an experimental design that has been used for estimating the average degree of dominance of quantitative trait loci (QTL) a...
journal_title：Genetics
pub_type： 杂志文章
doi：10.1534/genetics.107.082867
更新日期：2008-11-01 00:00:00
abstract：:Microsatellites have been widely used as tools for population studies. However, inference about population processes relies on the specification of mutation parameters that are largely unknown and likely to differ across loci. Here, we use data on somatic mutations to investigate the mutation process at 14 tetranucleo...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：2000-04-01 00:00:00
abstract：:Using conditional probabilities and moment-generating matrices, I derived approximate algebraic equations that give expectations of gene frequency, population mean, gene frequency variance within lines, or heterozygosity, and gene frequency variance between lines, or drift, for repeated cycles of recurrent selection i...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1980-07-01 00:00:00
abstract：:We present a two-part system for conditional FLP-out of FRT-flanked sequences in Caenorhabditis elegans to control gene activity in a spatially and/or temporally regulated manner. Using reporters, we assess the system for efficacy and demonstrate its use as a cell lineage marking tool. In addition, we construct and te...
journal_title：Genetics
pub_type： 杂志文章
doi：10.1534/genetics.108.090274
更新日期：2008-09-01 00:00:00
abstract：:The homeotic genes of the Drosophila bithorax complex are controlled by a large cis-regulatory region that ensures their segmentally restricted pattern of expression. A deletion that removes the Frontabdominal-7 cis-regulatory region (Fab-7') dominantly transforms parasegment 11 into parasegment 12. Previous studies s...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1997-08-01 00:00:00
abstract：:A series of clear mutants of the temperate phage 16-3 of Rhizobium meliloti were isolated that included various point and deletion mutants of the C cistron, coding for the phage repressor. It was observed that recombinant genotypes, such as c(+) and ti (temperature-sensitive allele), which form turbid plaques, can be ...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1980-02-01 00:00:00
abstract：:Thirty-four independent nonviable c-locus mutations (types cal, albino lethal and cas, albino subvital), derived from radiation experiments, were tested for involvement of nearby markers tp, Mod-2, sh-1, and Hbb: 10, 22, and 2 involved, respectively, none of these markers, Mod-2 alone, and Mod-2 plus sh-1. When classi...
journal_title：Genetics
pub_type： 杂志文章
doi：
更新日期：1982-03-01 00:00:00
abstract：:Neurospora crassa has been a model organism for the study of circadian clocks for the past four decades. Among natural accessions of Neurospora crassa, there is significant variation in clock phenotypes. In an attempt to investigate natural allelic variants contributing to quantitative variation, we used a quantitativ...
journal_title：Genetics
pub_type： 杂志文章
doi：10.1534/genetics.107.077958
更新日期：2007-12-01 00:00:00
abstract：:The challenges of breeding autotetraploid potato (Solanum tuberosum) have motivated the development of alternative breeding strategies. A common approach is to obtain uniparental dihaploids from a tetraploid of interest through pollination with S. tuberosum Andigenum Group (formerly S. phureja) cultivars. The mechanis...
journal_title：Genetics
pub_type： 杂志文章
doi：10.1534/genetics.119.302843
更新日期：2020-02-01 00:00:00
