Abstract：
:Cells expressing interleukin-1 (IL-1) were examined in rat periapical lesions using immunohistochemical methods. During the acute phase, both IL-1 alpha- and IL-1 beta-expressing cells were observed adjacent to many osteoclasts that contained large cytoplasms, and consequently the periapical lesions tended to expand. However, the number of IL-1 beta-expressing cells was about twice that of IL-1 alpha-expressing cells during the same period. On the other hand, there were significantly less IL-1 beta-expressing cells during the chronic phase and consequently a significant expansion of the periapical lesions was not seen. Furthermore, IL-1 alpha- and IL-1 beta-expressing cells were located far from the bone surfaces, whereas a fibroblastic cell layer lay between the IL-1-expressing cells and the bone surfaces. Both IL-1 alpha and IL-1 beta were mainly expressed by macrophages. In addition, after the percolated application of formocresol to experimentally induced periapical lesions, numerous macrophages expressing IL-1 beta became conspicuous within the vicinity of the extensive bone resorption sites. These results suggest that macrophages expressing IL-1 beta may play an important role in the activation and recrudescence of osteoclastic bone resorption, and this may be due to their localization close to the bone resorption sites noted within experimental periapical lesions.
journal_name
J Endodjournal_title
Journal of endodonticsauthors
Matsumoto A,Anan H,Maeda Kdoi
10.1016/S0099-2399(98)80008-3keywords:
subject
Has Abstractpub_date
1998-12-01 00:00:00pages
811-6issue
12eissn
0099-2399issn
1878-3554pii
S0099-2399(98)80008-3journal_volume
24pub_type
杂志文章abstract：:The purpose of this study was to evaluate the number of canals and isthmuses obturated after Cr, Er: YSGG laser treatment. Fifty-two canals were instrumented to a size 40 Profile 0.06 file combined with RC-Prep and sodium hypochlorite, or sterile water. The teeth were divided into 3 groups: (I) canals were flooded wit...
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2007.05.012
更新日期：2007-09-01 00:00:00
abstract：INTRODUCTION:Apical root resection is a biologically essential component in endodontic microsurgery. However, because it reduces the total root length and supported root surface, it changes the biomechanical response of the tooth. The purpose of this study was to analyze the biomechanical effect of apical root resectio...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.03.006
更新日期：2014-09-01 00:00:00
abstract：:A case study is presented that described an acute flare-up of a tooth following a vital bleaching procedure. The case illustrates (a) the importance of assessing the pulpal and periradicular status of a tooth prior to any vital bleaching procedure; and (b) the alteration of the local adaptation syndrome by the bleachi...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)80488-7
更新日期：1992-07-01 00:00:00
abstract：:This article describes how to construct and use a simplified model to demonstrate the operation of electronic root canal measuring devices. The model is effective, more economical than those previously described, and uses readily available materials. ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)81292-6
更新日期：1993-11-01 00:00:00
abstract：:This report documents the case of a patient who developed neuropathy that presented as dental pain and was later diagnosed with Lyme disease. A healthy female patient presented to the endodontist with toothache symptoms. Her symptoms included intense pain in the left mandible irradiating into the temporalis area and t...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2020.06.011
更新日期：2020-09-01 00:00:00
abstract：INTRODUCTION:The outcome of periapical surgery has been directly improved with the introduction of novel material formulations. The aim of the study was to compare the retrograde obturation quality of the following materials: calcium silicate (Biodentine; Septodont, Saint-Maur-des-Fosses, France), mineral trioxide aggr...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2017.09.022
更新日期：2018-05-01 00:00:00
abstract：:Many root canal instruments with several different designs have been introduced during recent years. This article evaluates the machining properties of four such instruments: the Flex-R, K-Flex, Trio-Cut, and S file. There are large variations in the machining properties of these instruments. The results are comparabl...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/s0099-2399(07)80200-7
更新日期：1990-12-01 00:00:00
abstract：:The purpose of this in vitro study was to evaluate the accuracy of Root ZX apex locator to determine the working length in teeth with simulated apical root resorption. Fifty extracted, single-rooted, human teeth with mature apices were used in this study. An irregular cavity defect was drilled at the apex of each toot...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200206000-00011
更新日期：2002-06-01 00:00:00
abstract：INTRODUCTION:This clinical study was conducted to measure the endotoxin levels in infected root canals (RCs) and exudates related to acute apical abscesses (AAAs). In addition, the effectiveness of RC procedures in reducing the endotoxin levels in RCs was monitored. METHODS:Paired samples of infected RCs and exudates ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2013.10.008
更新日期：2014-02-01 00:00:00
abstract：:A method is proposed for a three-dimensional visualization of the root canal system before and after the cleaning and shaping procedure to analyze the relationships of the root canal walls. The first part of the study provided cross-sections of the root perpendicular to the root canal. A system for remounting the sect...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)81298-7
更新日期：1993-05-01 00:00:00
abstract：INTRODUCTION:Apical surgery is frequently indicated in maxillary first molars. Occasionally, a vascular anastomosis in the lateral maxillary sinus wall can be observed during surgery. The aim of this study was to examine the distance between the vascular bone channel (VBC) and the root apices of maxillary first molars ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.09.004
更新日期：2019-12-01 00:00:00
abstract：INTRODUCTION:Various materials have been advocated for use as root-end filling materials. The purpose of the present in vitro study was to compare the cytotoxicity of 4 root-end filling materials: glass ionomer cement (GIC; Fuji II, GC Corp, Tokyo, Japan), reinforced zinc oxide-eugenol cement (IRM; Dentsply Tulsa Denta...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2012.09.004
更新日期：2012-12-01 00:00:00
abstract：INTRODUCTION:We performed a micro-computed tomographic assessment of the preparation of moderately single- and double-curved root canals using 3 single-file reciprocating nickel-titanium systems: S1 Plus Standard (Sendoline, Täby, Sweden), WaveOne Gold Primary (Dentsply Sirona, Ballaigues, Switzerland), and Reciproc R2...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2020.05.005
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:To evaluate in vitro the solubility of the Epiphany endodontic filling material Epiphany (Pentron Clinical Technologies, Wallingford, CT) prepared with its resinous solvent. METHODS:The specimens were prepared in the following experimental conditions: (1) GI, epiphany without photoactivation; (2) GII, Epiphany...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.01.021
更新日期：2009-05-01 00:00:00
abstract：:Aspirating the unknown contents of a bony cavity and saline irrigation of a body wound are both basic surgical techniques. These two techniques have been combined in treating persistent periradicular pathosis in two cases. The cases demonstrate significant bony healing of extensive periradicular defects after the use ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)81968-0
更新日期：1990-04-01 00:00:00
abstract：:Amalgam cores with cemented dowels are commonly used to restore endodontically treated teeth. These restorations were widely studied for their mechanical properties; however, less is known about their sealing ability. The effect of the cement type used for the dowel and that of a bonding agent application were studied...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200104000-00015
更新日期：2001-04-01 00:00:00
abstract：:In this study the sealing ability of a new urethane methacrylate resin-based sealer, EndoRez, was evaluated using a fluid-filtration model. Sixty-four single-rooted lower bicuspids were decoronated, instrumented, and divided into 3 groups of 20 each with 4 teeth used as controls. In group A, the roots were obturated w...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200310000-00011
更新日期：2003-10-01 00:00:00
abstract：INTRODUCTION:Dental pulp has limited capability to regenerate, which happens in the early stage of pulpitis. An ambiguous relationship exists; inflammation may impair or support pulp regeneration. Epigenetics, which is involved in cell proliferation and inflammation, could regulate human dental pulp cell (HDPCs) regene...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.01.031
更新日期：2014-08-01 00:00:00
abstract：:This randomized, double-blind trial tested the null hypothesis that speed of deposition has no influence on the injection discomfort, efficacy, distribution, and duration of pulp anesthesia after incisive/mental nerve block in adult volunteers. Thirty-eight subjects received incisive/mental nerve blocks of 2.0 mL lido...
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2007.07.016
更新日期：2007-10-01 00:00:00
abstract：:Coconut water is biologically pure and sterile, with a rich presence of amino acids, proteins, vitamins, and minerals. The purpose of this study was to use a collagenase-dispase assay to investigate the potential of a new storage medium, coconut water, in comparison with propolis, Hank's balanced salt solution (HBSS),...
journal_title：Journal of endodontics
pub_type： 杂志文章,收录出版
doi：10.1016/j.joen.2008.01.018
更新日期：2008-05-01 00:00:00
abstract：INTRODUCTION:This in vitro study compared the performance of the XP-endo Shaper (XP; FKG, La Chaux-de-Fonds, Switzerland) in curved canals when used with a higher speed (3000 rpm) without a glide path with the manufacturer's protocol. METHODS:Twenty extracted mandibular molars with separate mesial curved canals were m...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.10.014
更新日期：2020-01-01 00:00:00
abstract：:The putative hazardous nature of chloroform and xylene implies that safer substitutes should be considered. Standard cylindrical gutta-percha samples were immersed in Hemo-De, a xylene substitute, for 60 s at 37 degrees C. Weight loss of a sample, after drying, was used as a measure of its solubility. Master and acces...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200007000-00001
更新日期：2000-07-01 00:00:00
abstract：INTRODUCTION:Sphingosine-1-phosphate receptor 1 (S1P1) is crucial for regulation of immunity and bone metabolism. This study aimed to investigate the expression of S1P1 in rat periapical lesions and its relationship with receptor activator of nuclear factor kappa B ligand (RANKL) and regulatory T (Treg) cells. METHODS...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.10.010
更新日期：2015-04-01 00:00:00
abstract：INTRODUCTION:The objective of this study was to investigate the association between chronic apical periodontitis (CAP) and low-birth-weight preterm births (LBWPB). METHODS:Sixty-three women in postpartum period were included in this case-control study. The case group consisted of mothers of LBWPB infants (n = 33), and...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.11.018
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to evaluate the radiopacity of calcium aluminate cement (EndoBinder) with 3 different radiopacifiers (bismuth oxide, zinc oxide, or zirconium oxide) in comparison with gray mineral trioxide aggregate (GMTA), white MTA, and dental structures (enamel and dentin). METHODS:Eighteen t...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.10.001
更新日期：2011-01-01 00:00:00
abstract：:The cytotoxicity of four different calcium hydroxide-based root canal sealers (Sealapex, Apexit, CRCS, and Endoflas FS) was tested using human gingiva fibroblasts. The fibroblasts were acquired from the attached gingiva of apparently healthy patients. The sealers were allowed to set for 24 and 48 h before being covere...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)81309-9
更新日期：1992-03-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to evaluate the effects of different curing units and 2 luting cements on the push-out bond strength of a translucent fiber post. METHODS:Thirty maxillary incisor roots were endodontically treated. Post spaces were prepared, and the smear layers were removed. Posts (FRC Postec Pl...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.04.026
更新日期：2010-09-01 00:00:00
abstract：INTRODUCTION:Endodontic claims are the most frequently filed malpractice claims in dentistry. The aim of this study was to categorize and review errors and complications related to endodontic procedures that resulted in legal actions against the treating practitioner. METHODS:All dental malpractice complaints reported...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.03.030
更新日期：2010-06-01 00:00:00
abstract：INTRODUCTION:Neuropeptides play an important role in inflammation and repair and have been implicated in mediating angiogenesis. Pulp fibroblasts express neuropeptide receptors, and the aim of this research was to investigate whether neuropeptides could regulate angiogenic growth factor expression in vitro METHODS:An ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.03.005
更新日期：2009-06-01 00:00:00
abstract：:The aim of this study was to determine the relationship between histologic and radiologic signs of inflammation in human root-filled teeth. In addition, other factors with possible importance for apical inflammation were assessed. Fifty-three block sections of root-filled teeth were gathered from human cadavers. The b...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200402000-00003
更新日期：2004-02-01 00:00:00
