The prognostic value of the suPARnostic ELISA in HIV-1 infected individuals is not affected by uPAR promoter polymorphisms.

abstract：BACKGROUND:The Middle East respiratory syndrome (MERS) is proposed to be a zoonotic disease. Dromedary camels have been implicated due to reports that some confirmed cases were exposed to camels. Risk factors for MERS coronavirus (MERS-CoV) infections in humans are incompletely understood. This study aimed to describe ...

journal_title：BMC infectious diseases

authors： Aleanizy FS,Mohmed N,Alqahtani FY,El Hadi Mohamed RA

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:Prion diseases are caused by the accumulation of an aberrantly folded isoform of the prion protein, designated PrPSc. In a cell-based assay, quinacrine inhibits the conversion of normal host prion protein (PrPC) to PrPSc at a half-maximal concentration of 300 nM. While these data suggest that quinacrine may ...

journal_title：BMC infectious diseases

authors： Yung L,Huang Y,Lessard P,Legname G,Lin ET,Baldwin M,Prusiner SB,Ryou C,Guglielmo BJ

更新日期：2004-11-29 00:00:00

abstract：BACKGROUND:Escherichia coli infections are frequent in ICU patients. The increased resistance to fluoroquinolones and amoxicillin/clavulanate of this pathogen mandates the prescription of broad-spectrum antibiotics such as piperacillin/tazobactam (PIP-TAZ) or third generation cephalosporins (3GC). METHODS:To assess in...

journal_title：BMC infectious diseases

authors： Meybeck A,Ricard JD,Barnaud G,Eveillard M,Chevrel G,Mounier R,Dreyfuss D

更新日期：2008-05-17 00:00:00

abstract：BACKGROUND:Poor outcomes of invasive candidiasis (IC) are associated with the difficulty in establishing the microbiological diagnosis at an early stage. New scores and laboratory tests have been developed in order to make an early therapeutic intervention in an attempt to reduce the high mortality associated with inva...

journal_title：BMC infectious diseases

authors： Pemán J,Zaragoza R,Quindós G,Alkorta M,Cuétara MS,Camarena JJ,Ramírez P,Giménez MJ,Martín-Mazuelos E,Linares-Sicilia MJ,Pontón J,study group Candida albicans Germ Tube Antibody Detection in Critically Ill Patients.

更新日期：2011-03-09 00:00:00

abstract：BACKGROUND:Filamentous basidiomycetes are mainly considered to be respiratory tract colonizers but the clinical significance of their isolation in a specimen is debatable. Hormographiella aspergillata was first reported as a human pathogen in 1971. We discuss the role of this mold as a pathogen or colonizer and give an...

journal_title：BMC infectious diseases

authors： Moniot M,Lavergne RA,Morel T,Guieze R,Morio F,Poirier P,Nourrisson C

更新日期：2020-12-11 00:00:00

abstract：BACKGROUND:Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL). The reported association with pulmonary disease such as bronchiectasis is less certain. METHODS:A retrospective ...

journal_title：BMC infectious diseases

authors： Honarbakhsh S,Taylor GP

更新日期：2015-07-06 00:00:00

abstract：BACKGROUND:Lamivudine inhibits replication of both human immunodeficiency virus (HIV) and hepatitis B virus (HBV) and is commonly used as part of antiretroviral therapy. The main limitation in the use of lamivudine is resistant mutation selection. Most of these mutations affect the YMDD motif of the HBV DNA polymerase....

journal_title：BMC infectious diseases

authors： Santos EA,Sucupira MV,Arabe J,Gomes SA

更新日期：2004-08-31 00:00:00

abstract：BACKGROUND:In Tanzania, routine individual-level testing for HIV drug resistance (HIVDR) using laboratory genotyping and phenotyping is not feasible due to resource constraints. To monitor the prevention or emergence of HIVDR at a population level, WHO developed generic strategies to be adapted by countries, which incl...

journal_title：BMC infectious diseases

authors： Juma JM,Tiberio JK,Abuya MI,Kilama BK,Somi GR,Sambu V,Banda R,Jullu BS,Ramadhani AA

更新日期：2014-04-11 00:00:00

abstract：BACKGROUND:Pyrazinamide (PZA) plays a unique role in the treatment for multidrug-resistant tuberculosis (MDR-TB) in both first- and second-line regimens. The aim of this study was to investigate the prevalence and molecular characterization of PZA resistance among MDR-TB isolates collected in Chongqing municipality. M...

journal_title：BMC infectious diseases

authors： Pang Y,Zhu D,Zheng H,Shen J,Hu Y,Liu J,Zhao Y

更新日期：2017-11-06 00:00:00

abstract：BACKGROUND:Young people are disproportionately affected by sexually transmissible infections in Australia but face barriers to accessing sexual health services, including concerns over confidentiality and, for some, geographic remoteness. A possible innovation to increase access to services is the use of telemedicine. ...

journal_title：BMC infectious diseases

authors： Garrett CC,Hocking J,Chen MY,Fairley CK,Kirkman M

更新日期：2011-10-25 00:00:00

abstract：BACKGROUND:In Tashkent (Uzbekistan), TB treatment is provided in accordance with the DOTS strategy. Of 1087 pulmonary TB patients started on treatment in 2005, 228 (21%) defaulted. This study investigates who the defaulters in Tashkent are, when they default and why they default. METHODS:We reviewed the records of 126...

journal_title：BMC infectious diseases

authors： Hasker E,Khodjikhanov M,Usarova S,Asamidinov U,Yuldashova U,van der Werf MJ,Uzakova G,Veen J

更新日期：2008-07-22 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) is one of the most common sexually-transmitted pathogens. A number of studies in the literature have estimated the burden of HPV-related diseases by collecting data at primary care level, while a comprehensive assessment of the global burden of HPV-related diseases on hospital reso...

journal_title：BMC infectious diseases

authors： Baldo V,Cocchio S,Buja A,Baldovin T,Furlan P,Bertoncello C,Saia M

更新日期：2013-10-05 00:00:00

abstract：BACKGROUND:Several highly pathogenic avian influenza (AI) outbreaks have been reported over the past decade. South Korea recently faced AI outbreaks whose economic impact was estimated to be 6.3 billion dollars, equivalent to nearly 50% of the profit generated by the poultry-related industries in 2008. In addition, AI ...

journal_title：BMC infectious diseases

authors： Kim T,Hwang W,Zhang A,Sen S,Ramanathan M

更新日期：2010-08-10 00:00:00

abstract：BACKGROUND:For a long time, the role of CD8(+) T cells in blood-stage malaria was not considered important because erythrocytes do not express major histocompatibility complex (MHC) class I proteins. While recent evidences suggest that CD8(+) T cells may play an important role during the erythrocytic phase of infection...

journal_title：BMC infectious diseases

authors： Hojo-Souza NS,Pereira DB,Passos LS,Gazzinelli-Guimarães PH,Cardoso MS,Tada MS,Zanini GM,Bartholomeu DC,Fujiwara RT,Bueno LL

更新日期：2015-01-31 00:00:00

abstract：BACKGROUND:Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B. pertussis infection alone and those with respiratory viral coinfections. We also a...

journal_title：BMC infectious diseases

authors： Frassanito A,Nenna R,Nicolai A,Pierangeli A,Tozzi AE,Stefanelli P,Carsetti R,Concato C,Schiavoni I,Midulla F,Pertussis study group.

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:An ongoing outbreak of coronavirus disease 2019 (COVID-19) is spreading globally. Recently, several articles have mentioned that the early acute respiratory distress syndrome (ARDS) caused by COVID-19 significantly differ from those of ARDS due to other causes. Actually, we newly observed that some mechanica...

journal_title：BMC infectious diseases

authors： Xia J,Feng Y,Li M,Yu X,Zhang Y,Duan J,Zhan Q

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Infection by Staphylococcus aureus (S. aureus) is a major cause of morbidity and mortality. Colonization by S. aureus increases the risk of infection. Little is known about decolonization strategies for S. aureus beyond antibiotics, however probiotics represent a promising alternative. A randomized controlle...

journal_title：BMC infectious diseases

authors： Eggers S,Barker AK,Valentine S,Hess T,Duster M,Safdar N

更新日期：2018-03-14 00:00:00

abstract：BACKGROUND:The rapid identification of acid-fast bacilli recovered from patient specimens as Mycobacterium tuberculosis complex (MTC) is critically important for accurate diagnosis and treatment. A thin-layer immunochromatographic (TLC) assay using anti-MPB64 or anti-MPT64 monoclonal antibodies was developed to discrim...

journal_title：BMC infectious diseases

authors： Chikamatsu K,Aono A,Yamada H,Sugamoto T,Kato T,Kazumi Y,Tamai K,Yanagisawa H,Mitarai S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Models of infectious disease are increasingly utilising empirical contact data to quantify the number of potentially infectious contacts between age groups. While a growing body of data is being collected on contact patterns across many populations, less attention has been paid to the social contacts of youn...

journal_title：BMC infectious diseases

authors： Campbell PT,McVernon J,Shrestha N,Nathan PM,Geard N

更新日期：2017-09-20 00:00:00

abstract：BACKGROUND:HIV-related stigma always is major obstacles to an effective HIV response worldwide. The effect of HIV-related stigma on HIV prevention and treatment is particularly serious in China. This study was to examine stigma attitude towards people living with HIV/AIDS (PLWHA) among general individuals in Heilongjia...

journal_title：BMC infectious diseases

authors： Li X,Yuan L,Li X,Shi J,Jiang L,Zhang C,Yang X,Zhang Y,Zhao D,Zhao Y

更新日期：2017-02-17 00:00:00

abstract：BACKGROUND:Antimicrobial overuse and misuse of broad-spectrum antibiotics increases the risk for antimicrobial resistance. Investigating unwarranted variation in antibiotic prescription has therefore gained global priority. METHODS:We examined recent time trends in the utilization of narrow- and broad-spectrum antibio...

journal_title：BMC infectious diseases

authors： Kristensen PK,Johnsen SP,Thomsen RW

更新日期：2019-04-24 00:00:00

abstract：BACKGROUND:Recently we developed and validated generic quality indicators that define 'appropriate antibiotic use' in hospitalized adults treated for a (suspected) bacterial infection. Previous studies have shown that with appropriate antibiotic use a reduction of 13% of length of hospital stay can be achieved. Our mai...

journal_title：BMC infectious diseases

authors： van Daalen FV,Prins JM,Opmeer BC,Boermeester MA,Visser CE,van Hest RM,Hulscher ME,Geerlings SE

更新日期：2015-03-19 00:00:00

abstract：BACKGROUND:In the pre-vaccine era, invasive disease with Haemophilus influenzae, type b (Hib) commonly presented with osteoarticular involvement. Haemophilus influenzae, type a (Hia) sepsis is a rare but emerging problem in recent years. Here, we report a case of sepsis with concomitant osteoarthritis due to Hia that w...

journal_title：BMC infectious diseases

authors： Albrecht T,Poss K,Issaranggoon Na Ayuthaya S,Triden L,Schleiss KL,Schleiss MR

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:Early infant diagnosis of HIV infection is challenging in sub-Saharan Africa, particularly in rural areas, leading to delays in diagnosis and treatment. Use of a point-of-care test would overcome many challenges. This study evaluated the validity of a novel point-of-care p24 antigen detection test (LYNX) in ...

journal_title：BMC infectious diseases

authors： Sutcliffe CG,Mutanga J,Moyo N,Agarwal AK,Schue JL,Hamahuwa M,Palamountain KM,Fisher MJ,Elghanian R,Thuma PE,Moss WJ

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:Antiretroviral therapy dramatically reduced HIV-related morbidity and mortality, prolonging the lifespan of HIV-infected patients. Greater duration of infection and exposure to antiretroviral therapy makes these patients susceptible to traditional cardio-metabolic risk factors and pathologies. The optimal di...

journal_title：BMC infectious diseases

authors： Coelho AR,Moreira FA,Santos AC,Silva-Pinto A,Sarmento A,Carvalho D,Freitas P

更新日期：2018-07-06 00:00:00

abstract：BACKGROUND:The rate of vertical HIV transmission has decreased in Brazil, but regional inequalities suggest problems in implementing control measures during pregnancy and delivery. The aims of this study were to ascertain the coverage of HIV testing during prenatal care and estimate the prevalence of HIV infection duri...

journal_title：BMC infectious diseases

authors： Domingues RM,Szwarcwald CL,Souza PR Jr,Leal Mdo C

更新日期：2015-02-26 00:00:00

abstract：BACKGROUND:HIV affects the central nervous system resulting in HIV associated neurocognitive impairment (NCI) in approximately 50% of people living with HIV. It typically affects memory, learning, working memory, fine motor skills, speed of information processing, verbal fluency and executive functioning cognitive doma...

journal_title：BMC infectious diseases

authors： Nyamayaro P,Gouse H,Hakim J,Robbins RN,Chibanda D

更新日期：2020-05-29 00:00:00

abstract：BACKGROUND:The seasonality, clinical and radiographic features and outcome of aseptic meningitis have been described for regional outbreaks but data from a wider geographic area is necessary to delineate the epidemiology of this condition. METHODS:A retrospective chart review was completed of children presenting with ...

journal_title：BMC infectious diseases

authors： Lee BE,Chawla R,Langley JM,Forgie SE,Al-Hosni M,Baerg K,Husain E,Strong J,Robinson JL,Allen U,Law BJ,Dobson S,Davies HD

更新日期：2006-04-10 00:00:00

abstract：BACKGROUND:Carbapenem-resistant Enterobacteriaceae (CRE) represent an important global threat. The aim of this study is to describe the clinical course and outcomes of patients with CRE infections treated with ceftazidime-avibactam (CAZ-AVI) compared to patients treated with other agents. METHODS:A retrospective cohor...

journal_title：BMC infectious diseases

authors： Alraddadi BM,Saeedi M,Qutub M,Alshukairi A,Hassanien A,Wali G

更新日期：2019-09-04 00:00:00

abstract：BACKGROUND:The diagnosis of typhoid fever is confirmed by culture of Salmonella enterica serotype Typhi (S. typhi). However, a more rapid, simpler, and cheaper diagnostic method would be very useful especially in developing countries. The Widal test is widely used in Africa but little information exists about its relia...

journal_title：BMC infectious diseases

authors： Ley B,Mtove G,Thriemer K,Amos B,von Seidlein L,Hendriksen I,Mwambuli A,Shoo A,Malahiyo R,Ame SM,Kim DR,Ochiai LR,Clemens JD,Reyburn H,Wilfing H,Magesa S,Deen JL

更新日期：2010-06-22 00:00:00