Prevalence and molecular characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates from Southern China.

abstract：BACKGROUND:Within the genus Aspergillus, A. flavus is the second most important species of clinical significance. It is predominantly associated with infections involving sinuses, eye and skin, mostly in geographic regions with hot and arid climate, including the Middle East. Recent reports on emergence of resistance t...

journal_title：BMC infectious diseases

authors： Al-Wathiqi F,Ahmad S,Khan Z

更新日期：2013-03-06 00:00:00

abstract：BACKGROUND:Lateral gene transfer is the major mechanism for acquisition of new virulence genes in pathogens. Recent whole genome analyses have suggested massive gene transfer between widely divergent organisms. PRESENTATION OF THE HYPOTHESIS:Archeal-like genes acting as virulence genes are present in several pathogens...

journal_title：BMC infectious diseases

authors： Faguy DM

更新日期：2003-06-19 00:00:00

abstract：BACKGROUND:In Ethiopia a tiebreaker algorithm using 3 rapid diagnostic tests (RDTs) in series is used to diagnose HIV. Discordant results between the first 2 RDTs are resolved by a third 'tiebreaker' RDT. Médecins Sans Frontières uses an alternate serial algorithm of 2 RDTs followed by a confirmation test for all doubl...

journal_title：BMC infectious diseases

authors： Shanks L,Siddiqui MR,Kliescikova J,Pearce N,Ariti C,Muluneh L,Pirou E,Ritmeijer K,Masiga J,Abebe A

更新日期：2015-02-03 00:00:00

abstract：BACKGROUND:While cultivation of pathogens represents a foundational diagnostic approach in the study of infectious diseases, its value for the confirmation of clinical diagnosis of Buruli ulcer is limited by the fact that colonies of Mycobacterium ulcerans appear only after about eight weeks of incubation at 30°C. Howe...

journal_title：BMC infectious diseases

authors： Bratschi MW,Bolz M,Grize L,Kerber S,Minyem JC,Um Boock A,Yeboah-Manu D,Ruf MT,Pluschke G

更新日期：2014-11-30 00:00:00

abstract：BACKGROUND:There is a high incidence of diarrhea in traveling populations. Norovirus (NV) infection is a common cause of diarrhea and is associated with 7% of all diarrhea related deaths in the US. However, data on the overall prevalence of NV infection in traveling populations is limited. Furthermore, the prevalence o...

journal_title：BMC infectious diseases

authors： Apelt N,Hartberger C,Campe H,Löscher T

更新日期：2010-05-25 00:00:00

abstract：BACKGROUND:Cytopenias are the most common HIV-associated hematological abnormality. Cytopenias have been associated with several factors including sex, race/ethnicity, geographical location and comorbidities such as tuberculosis, hepatitis B infection, fever and oral candidiasis. Cytopenias become more prevalent as HIV...

journal_title：BMC infectious diseases

authors： Kyeyune R,Saathoff E,Ezeamama AE,Löscher T,Fawzi W,Guwatudde D

更新日期：2014-09-10 00:00:00

abstract：BACKGROUND:Low absolute humidity (AH) has been associated with increased influenza virus survival and transmissibility and the onset of seasonal influenza outbreaks. Humidification of indoor environments may mitigate viral transmission and may be an important control strategy, particularly in schools where viral transm...

journal_title：BMC infectious diseases

authors： Koep TH,Enders FT,Pierret C,Ekker SC,Krageschmidt D,Neff KL,Lipsitch M,Shaman J,Huskins WC

更新日期：2013-02-05 00:00:00

abstract：BACKGROUND:Compliance to anti-TB treatment is crucial in achieving cure and avoiding the emergence of drug resistance. Electronic health (eHealth) interventions are included in the strategy to end the global Tuberculosis (TB) epidemic by 2035. Evidences showed that mobile messaging systems could improve patient adheren...

journal_title：BMC infectious diseases

authors： Gashu KD,Gelaye KA,Mekonnen ZA,Lester R,Tilahun B

更新日期：2020-01-14 00:00:00

abstract：BACKGROUND:Antimicrobial resistance in Mycoplasma genitalium is rising globally with resultant clinical treatment failure. We investigated the prevalence of mutations in the macrolide and fluoroquinolone resistance-determining regions of M. genitalium in Johannesburg, South Africa, and ascertained their association wit...

journal_title：BMC infectious diseases

authors： Muller EE,Mahlangu MP,Lewis DA,Kularatne RS

更新日期：2019-02-13 00:00:00

abstract：BACKGROUND:Mycoplasmas are present worldwide in a large number of animal hosts. Due to their small genome and parasitic lifestyle, Mycoplasma spp. require complex isolation media. Nevertheless, already over 100 different species have been identified and characterized and their number increases as more hosts are sampled...

journal_title：BMC infectious diseases

authors： Stakenborg T,Vicca J,Butaye P,Maes D,De Baere T,Verhelst R,Peeters J,de Kruif A,Haesebrouck F,Vaneechoutte M

更新日期：2005-06-14 00:00:00

abstract：BACKGROUND:Regardless of chronic treatment with antiretroviral therapy (ART), the switching rate for ART regarding anchor drugs has not been articulated in real-world clinical-settings in Japan. We assessed switch rates and time-to-switch of ART regimens according to anchor drug classes (integrase strand transfer inhib...

journal_title：BMC infectious diseases

authors： Ruzicka DJ,Kuroishi N,Oshima N,Sakuma R,Naito T

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:To verify whether a daily service of Infectious Diseases consultation (ID-cons) is more effective than a weekly service in reducing antibiotic (ATB) consumption without worsening of clinical outcomes. METHODS:Two-year observational analysis of the ID-cons provided in a hospital setting in Milan, Italy. ID-c...

journal_title：BMC infectious diseases

authors： Cona A,Gazzola L,Viganò O,Bini T,Marchetti GC,d'Arminio Monforte A

更新日期：2020-11-07 00:00:00

abstract：BACKGROUND:Emerging molecular, animal model and epidemiologic evidence suggests that Shiga-toxigenic Escherichia coli O157:H7 (STEC O157) isolates vary in their capacity to cause human infection and disease. The translocated intimin receptor (tir) and intimin (eae) are virulence factors and bacterial receptor-ligand pr...

journal_title：BMC infectious diseases

authors： Bono JL,Keen JE,Clawson ML,Durso LM,Heaton MP,Laegreid WW

更新日期：2007-08-24 00:00:00

abstract：BACKGROUND:During the fifth wave of human H7N9 infections, a novel highly pathogenic (HP) H7N9 variant emerged with an insertion of multiple basic amino acids in the HA cleavage site. Moreover, a neuraminidase inhibitor (NAI) resistance (R292K in NA) mutation was found in H7N9 isolates from humans, poultry and the envi...

journal_title：BMC infectious diseases

authors： Yang Y,Li S,Wong G,Ma S,Xu Z,Zhao X,Li H,Xu W,Zheng H,Lin J,Zhao Q,Liu W,Liu Y,Gao GF,Bi Y

更新日期：2018-08-15 00:00:00

abstract：BACKGROUND:Non-adherence to tuberculosis (TB) treatment is the most important cause of poor TB outcomes, and improving support for TB patients is a primary priority for governments, but there has been little research on the effects of family, social and national policy support factors on TB treatment adherence. The cur...

journal_title：BMC infectious diseases

authors： Chen X,Du L,Wu R,Xu J,Ji H,Zhang Y,Zhu X,Zhou L

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Due to limited therapeutic options, the spread of extended-spectrum beta-lactamases (ESBLs) have become a major public health concern. We conducted a prospective, randomized, open-label comparison of the therapeutic efficacy of piperacillin-tazobactam (PTZ), cefepime, and ertapenem in febrile nosocomial urin...

journal_title：BMC infectious diseases

authors： Seo YB,Lee J,Kim YK,Lee SS,Lee JA,Kim HY,Uh Y,Kim HS,Song W

更新日期：2017-06-07 00:00:00

abstract：BACKGROUND:In resource-limited settings, such as Kenya, access to CD4 testing is limited. Therefore, evaluation of less expensive laboratory diagnostics is urgently needed to diagnose immuno-suppression in children. OBJECTIVES:To evaluate utility of total lymphocyte count (TLC) as surrogate marker for CD4 count in HIV...

journal_title：BMC infectious diseases

authors： Githinji N,Maleche-Obimbo E,Nderitu M,Wamalwa DC,Mbori-Ngacha D

更新日期：2011-09-30 00:00:00

abstract：BACKGROUND:The World Health Organization (WHO) recommends viral load (VL) measurement as the preferred monitoring strategy for HIV-infected individuals on antiretroviral therapy (ART) in resource-limited settings. The new WHO guidelines 2016 continue to define virologic failure as two consecutive VL ≥1000 copies/mL (at...

journal_title：BMC infectious diseases

authors： Amstutz A,Nsakala BL,Vanobberghen F,Muhairwe J,Glass TR,Achieng B,Sepeka M,Tlali K,Sao L,Thin K,Klimkait T,Battegay M,Labhardt ND

更新日期：2018-02-12 00:00:00

abstract：BACKGROUND:Placental malaria (PM) is associated with prenatal malaise, but many PM+ infants are born without symptoms. As malaria has powerful immunomodulatory effects, we tested the hypothesis that PM predicts reduced T-cell responses to vaccine challenge. METHODS:We recruited healthy PM+ and PM- infants at birth. At...

journal_title：BMC infectious diseases

authors： Walther B,Miles DJ,Waight P,Palmero MS,Ojuola O,Touray ES,Whittle H,van der Sande M,Crozier S,Flanagan KL

更新日期：2012-01-14 00:00:00

abstract：BACKGROUND:The use of cell culture for the diagnosis of human metapneumovirus (hMPV) infection is uncommon at present and molecular method such as reverse-transcription PCR (RT-PCR) has been widely and most commonly used as the preferred test. We aimed to compare the results of virus isolation using Vero E6 cells with ...

journal_title：BMC infectious diseases

authors： Matsuzaki Y,Mizuta K,Takashita E,Okamoto M,Itagaki T,Katsushima F,Katsushima Y,Nagai Y,Nishimura H

更新日期：2010-06-14 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) is one of the most common sexually-transmitted pathogens. A number of studies in the literature have estimated the burden of HPV-related diseases by collecting data at primary care level, while a comprehensive assessment of the global burden of HPV-related diseases on hospital reso...

journal_title：BMC infectious diseases

authors： Baldo V,Cocchio S,Buja A,Baldovin T,Furlan P,Bertoncello C,Saia M

更新日期：2013-10-05 00:00:00

abstract：BACKGROUND:The accuracy of a new optical biosensor (OB) point-of-care device for the detection of severe infections is studied. METHODS:The OB emits different wavelengths and outputs information associated with heart rate, pulse oximetry, levels of nitric oxide and kidney function. At the first phase, recordings were ...

journal_title：BMC infectious diseases

authors： Doulou S,Leventogiannis K,Tsilika M,Rodencal M,Katrini K,Antonakos N,Kyprianou M,Karofylakis E,Karageorgos A,Koufargyris P,Christopoulos G,Kassianidis G,Stamatelopoulos K,Newberry R,Giamarellos-Bourboulis EJ

更新日期：2020-11-19 00:00:00

abstract：BACKGROUND:The purpose of this study was to further characterize the immune response to Mycobacterium tuberculosis (Mtb) antigens, in order to provide new insight into host-pathogen interactions in tuberculosis (TB), and to offer tools for a more accurate diagnosis of the different stages of TB. METHODS:T-cell respons...

journal_title：BMC infectious diseases

authors： Sargentini V,Mariotti S,Carrara S,Gagliardi MC,Teloni R,Goletti D,Nisini R

更新日期：2009-06-23 00:00:00

abstract：BACKGROUND:Drug resistant tuberculosis is a major public health problem in Morocco and worldwide. Treatment outcome of drug resistant tuberculosis is poor and requires a long period of treatment with many toxic and expensive antituberculosis drugs. The aim of this study is to evaluate treatment outcomes of drug resista...

journal_title：BMC infectious diseases

authors： El Hamdouni M,Bourkadi JE,Benamor J,Hassar M,Cherrah Y,Ahid S

更新日期：2019-04-11 00:00:00

abstract：BACKGROUND:Altered fat distribution and chronic inflammation are found in both persons living with HIV (PLWH) and persons with diabetes mellitus type 2 (DM2) and are known risk factors for cardiovascular diseases (CVD). We aimed to investigate if a synergistic effect of HIV infection and DM2 was found on fat distributi...

journal_title：BMC infectious diseases

authors： Hove-Skovsgaard M,Abildgaard J,Gelpi M,Gaardbo JC,Kolte L,Ullum H,Trøseid M,Lindegaard B,Nielsen SD

更新日期：2020-11-25 00:00:00

abstract：BACKGROUND:There are few reports in the literature of invasive infection caused by Brevundimonas vesicularis in patients without immunosuppression or other predisposing factors. The choice of antimicrobial therapy for bacteremia caused by the pathogen requires more case experience to be determined. CASE PRESENTATION:T...

journal_title：BMC infectious diseases

authors： Yang ML,Chen YH,Chen TC,Lin WR,Lin CY,Lu PL

更新日期：2006-12-29 00:00:00

abstract：BACKGROUND:This epidemiological study was carried out in Sfax (south of Tunisia) and focused on genital Chlamydia trachomatis (C. trachomatis) genovar distribution. METHODS:One hundred and thirty seven genital samples from 4067 patients (4.2%) attending the Habib Bourguiba University hospital of Sfax over 12 years (fr...

journal_title：BMC infectious diseases

authors： Gharsallah H,Frikha-Gargouri O,Sellami H,Besbes F,Znazen A,Hammami A

更新日期：2012-11-30 00:00:00

abstract：BACKGROUND:Rituximab, a monoclonal antibody directed against CD20, is approved for the treatment of CD20-positive B-cell Non-Hodgkin's lymphoma and rheumatologic disorders. Due to its potent activity in depleting CD20-positive lymphocytes, the influence on opportunistic infections is still under discussion. Thus, we an...

journal_title：BMC infectious diseases

authors： Nissen JC,Hummel M,Brade J,Kruth J,Hofmann WK,Buchheidt D,Reinwald M

更新日期：2014-07-03 00:00:00

abstract：BACKGROUND:Respiratory viral diagnosis of upper respiratory tract infections has largely developed through multiplex molecular techniques. Although the sensitivity of different types of upper respiratory tract samples seems to be correlated to the number of sampled cells, this link remains largely unexplored. METHODS:...

journal_title：BMC infectious diseases

authors： Bonnin P,Miszczak F,Kin N,Resa C,Dina J,Gouarin S,Viron F,Morello R,Vabret A

更新日期：2016-08-09 00:00:00

abstract：BACKGROUND:The importance of multidrug-resistant organisms (MDRO) in Chinese hospitals is not clearly delineated. Thus we sought to assess the prevalence of MDRO in Chinese intensive care units (ICUs). METHODS:Prospective study of inpatients admitted consecutively to eight ICUs in four Chinese cities in 2009-10. Admis...

journal_title：BMC infectious diseases

authors： Ma X,Wu Y,Li L,Xu Q,Hu B,Ni Y,Wu A,Sun S,Jarlier V,Robert J

更新日期：2015-08-21 00:00:00