Maternal age and fetal loss: population based register linkage study.

abstract：OBJECTIVE:To study changes from 1969 to 1983 in the prognosis of patients with acute myocardial infarction treated in a coronary care unit. DESIGN:Mortality follow up of all patients with definite acute myocardial infarction. SETTING:The coronary care unit of the Royal Melbourne Hospital, a tertiary referral centre. ...

journal_title：BMJ (Clinical research ed.)

authors： Hopper JL,Pathik B,Hunt D,Chan WW

更新日期：1989-10-07 00:00:00

abstract：OBJECTIVE:To confirm the findings of pilot studies that interferon alfa is an effective treatment of Europid men with chronic hepatitis B virus infection. DESIGN:Randomised controlled trial of three months treatment with interferon alfa followed by 12 months of observation. SETTING:Outpatient clinic of a tertiary ref...

journal_title：BMJ (Clinical research ed.)

authors： Brook MG,Chan G,Yap I,Karayiannis P,Lever AM,Jacyna M,Main J,Thomas HC

更新日期：1989-09-09 00:00:00

abstract：OBJECTIVES:To investigate the association between four sociodemographic measures (unemployment, overcrowding, low social class, and the proportion of migrants from areas of high prevalence of tuberculosis) and average level and rate of change of notification rates for tuberculosis. DESIGN:Ecological analysis of both t...

journal_title：BMJ (Clinical research ed.)

authors： Mangtani P,Jolley DJ,Watson JM,Rodrigues LC

更新日期：1995-04-15 00:00:00

abstract：OBJECTIVE:To describe the association between epithelial cell IgM, which has previously been associated with an increased incidence of loss of renal graft in children, with a novel cutaneous eruption and unexplained native renal disease. DESIGN:Observational study on children with epithelial cell antibody presenting w...

journal_title：BMJ (Clinical research ed.)

authors： Deal JE,Groves RW,Harmer AW,Welsh KI,MacDonald DM,Rigden SP

更新日期：1991-07-20 00:00:00

abstract：OBJECTIVES:To identify the genetic determinants of fracture risk and assess the role of 15 clinical risk factors on osteoporotic fracture risk. DESIGN:Meta-analysis of genome wide association studies (GWAS) and a two-sample mendelian randomisation approach. SETTING:25 cohorts from Europe, United States, east Asia, an...

journal_title：BMJ (Clinical research ed.)

authors： Trajanoska K,Morris JA,Oei L,Zheng HF,Evans DM,Kiel DP,Ohlsson C,Richards JB,Rivadeneira F,GEFOS\/GENOMOS consortium and the 23andMe research team.

更新日期：2018-08-29 00:00:00

abstract：OBJECTIVE:To examine the impact of antenatal supplementation with multiple micronutrients or iron and folic acid compared with folic acid alone on birth weight, duration of gestation, and maternal haemoglobin concentration in the third trimester. DESIGN:Cluster randomised double blind controlled trial. SETTING:Two ru...

journal_title：BMJ (Clinical research ed.)

authors： Zeng L,Dibley MJ,Cheng Y,Dang S,Chang S,Kong L,Yan H

更新日期：2008-11-07 00:00:00

abstract：OBJECTIVE:To examine the associations of a vegetarian diet and dietary fibre intake with risk of diverticular disease. DESIGN:Prospective cohort study. SETTING:The EPIC-Oxford study, a cohort of mainly health conscious participants recruited from around the United Kingdom. PARTICIPANTS:47,033 men and women living in...

journal_title：BMJ (Clinical research ed.)

authors： Crowe FL,Appleby PN,Allen NE,Key TJ

更新日期：2011-07-19 00:00:00

abstract：OBJECTIVE:To determine the global capacity (availability, accessibility, quality, and affordability) to deliver kidney replacement therapy (dialysis and transplantation) and conservative kidney management. DESIGN:International cross sectional survey. SETTING:International Society of Nephrology (ISN) survey of 182 cou...

journal_title：BMJ (Clinical research ed.)

authors： Bello AK,Levin A,Lunney M,Osman MA,Ye F,Ashuntantang GE,Bellorin-Font E,Benghanem Gharbi M,Davison SN,Ghnaimat M,Harden P,Htay H,Jha V,Kalantar-Zadeh K,Kerr PG,Klarenbach S,Kovesdy CP,Luyckx VA,Neuen BL,O'Donoghue D

更新日期：2019-10-31 00:00:00

abstract：OBJECTIVE:To examine the predictors of long term outcome for patients with the chronic fatigue syndrome. DESIGN:Cohort study. SUBJECTS:139 subjects previously enrolled in two treatment trials; 103 (74%) were reassessed a mean of 3.2 years after start of the trials. SETTING:University hospital referral centre. MAIN ...

journal_title：BMJ (Clinical research ed.)

authors： Wilson A,Hickie I,Lloyd A,Hadzi-Pavlovic D,Boughton C,Dwyer J,Wakefield D

更新日期：1994-03-19 00:00:00

abstract：OBJECTIVE:To assess whether a late evening meal would improve nitrogen balance in patients with cirrhosis of the liver. DESIGN:Randomised crossover study of meal schedules comparing three meals a day with four or six meals a day, the four and six meal schedules both including a late evening meal (2300). SETTING:Metab...

journal_title：BMJ (Clinical research ed.)

authors： Swart GR,Zillikens MC,van Vuure JK,van den Berg JW

更新日期：1989-11-11 00:00:00

abstract：OBJECTIVES:To investigate whether the use of graduated compression stockings (GCS) offers any adjuvant benefit when pharmaco-thromboprophylaxis is used for venous thromboembolism prophylaxis in patients undergoing elective surgery. DESIGN:Open, multicentre, randomised, controlled, non-inferiority trial. SETTING:Seven...

journal_title：BMJ (Clinical research ed.)

authors： Shalhoub J,Lawton R,Hudson J,Baker C,Bradbury A,Dhillon K,Everington T,Gohel MS,Hamady Z,Hunt BJ,Stansby G,Warwick D,Norrie J,Davies AH,GAPS trial investigators.

更新日期：2020-05-13 00:00:00

abstract：:There is currently much debate about how to improve undergraduate medical education, and in particular on how best to prepare students for clinical responsibility. For 20 years a period of trainee internship has formed part of New Zealand medical students' undergraduate training, and the model could have much to offer...

journal_title：BMJ (Clinical research ed.)

authors： Allen PI,Colls BM

更新日期：1994-02-05 00:00:00

abstract：OBJECTIVE:To increase understanding of how the prison environment influences the mental health of prisoners and prison staff. DESIGN:Qualitative study with focus groups. SETTING:A local prison in southern England. PARTICIPANTS:Prisoners and prison staff. RESULTS:Prisoners reported that long periods of isolation wit...

journal_title：BMJ (Clinical research ed.)

authors： Nurse J,Woodcock P,Ormsby J

更新日期：2003-08-30 00:00:00

abstract：OBJECTIVES:To determine the relation between the HIV/AIDS epidemic and support for dependent elderly people in Africa. DESIGN:Retrospective analysis using data from Demographic and Health Surveys. SETTING:22 African countries between 1991 and 2006. PARTICIPANTS:123,176 individuals over the age of 60. MAIN OUTCOME M...

journal_title：BMJ (Clinical research ed.)

authors： Kautz T,Bendavid E,Bhattacharya J,Miller G

更新日期：2010-06-16 00:00:00

abstract：OBJECTIVE:To evaluate the effect of support with human chorionic gonadotrophin in the luteal phase in women taking part in an in vitro fertilisation programme after buserelin and human menopausal gonadotrophin were used to hyperstimulate their ovaries. DESIGN:Controlled group comparison. SETTING:Outpatient department...

journal_title：BMJ (Clinical research ed.)

authors： Smith EM,Anthony FW,Gadd SC,Masson GM

更新日期：1989-06-03 00:00:00

abstract：:Current services for those with mental disorders show two trends. Psychiatric services are becoming concentrated on the care of those with "severe mental illness," largely (but unjustifiably) synonymous with chronic psychosis. The retreat of psychiatry from the care of those with non-psychotic mental disorders has hel...

journal_title：BMJ (Clinical research ed.)

authors： Wessely S

更新日期：1996-07-20 00:00:00

abstract：:The disease management approach to patient care seeks to coordinate resources across the healthcare delivery system. The growing interest in evidence based medicine and outcomes, and a commitment to integrated care across the primary, secondary, and community care sectors, all contribute to making disease management a...

journal_title：BMJ (Clinical research ed.)

authors： Hunter DJ,Fairfield G

更新日期：1997-07-05 00:00:00

abstract：OBJECTIVE:To investigate the association of enteroviruses with motor neurone disease, also known as amyotrophic lateral sclerosis. DESIGN:Analysis by enterovirus polymerase chain reaction of wax embedded material from spinal cords taken at necropsy from subjects with motor neurone disease and from age and sex matched ...

journal_title：BMJ (Clinical research ed.)

authors： Woodall CJ,Riding MH,Graham DI,Clements GB

更新日期：1994-06-11 00:00:00

abstract：OBJECTIVE:To assess the risk of hyperglycaemia with two standard oral rehydration solutions that contain carbohydrate compared with a carbohydrate free solution during rehydration of diabetic patients with acute diarrhoea. DESIGN:Prospective randomised allocation to one of three oral rehydration solutions (World Healt...

journal_title：BMJ (Clinical research ed.)

authors： Haider R,Azad Khan AK,Roy SK,Dewan N,Alam AN,Mahalanabis D

更新日期：1994-03-05 00:00:00

abstract：OBJECTIVE:To assess the associations between different antidepressant treatments and the rates of suicide and attempted suicide or self harm in people with depression. DESIGN:Cohort study. SETTING:Patients registered with UK general practices contributing data to the QResearch database. PARTICIPANTS:238,963 patients...

journal_title：BMJ (Clinical research ed.)

authors： Coupland C,Hill T,Morriss R,Arthur A,Moore M,Hippisley-Cox J

更新日期：2015-02-18 00:00:00

abstract：OBJECTIVE:To examine the associations between neuraxial anaesthesia or general anaesthesia and clinical outcomes, length of hospital stay, and readmission in adults undergoing lower limb revascularisation surgery. DESIGN:Comparative effectiveness study using linked, validated, population based databases. SETTING:Onta...

journal_title：BMJ (Clinical research ed.)

authors： Roberts DJ,Nagpal SK,Kubelik D,Brandys T,Stelfox HT,Lalu MM,Forster AJ,McCartney CJ,McIsaac DI

更新日期：2020-11-25 00:00:00

abstract：:Environmental issues tend to greater political attention than do environmental health aspects. Therefore, when conflicts of interest occur with other environmental concerns, negative consequences for public health may result. For example, a strategy to substantially reduce indoor ventilation in many dwellings in Sca...

journal_title：BMJ (Clinical research ed.)

authors： Pershagen G

更新日期：1999-06-19 00:00:00

abstract：OBJECTIVES:To determine whether fibrinogen and lipid concentrations are risk factors for ischaemic stroke. DESIGN:Case-control study with a population based comparison within the overall study. SETTING:Oxfordshire community stroke project and a neurology clinic. SUBJECTS:105 patients who had a transient ischaemic at...

journal_title：BMJ (Clinical research ed.)

authors： Qizilbash N,Jones L,Warlow C,Mann J

更新日期：1991-09-14 00:00:00

abstract：OBJECTIVES:To identify and calculate the prevalence of spin in studies of spin. DESIGN:Meta-research analysis (research on research). SETTING:35 studies of spin in the scientific literature. MAIN OUTCOME MEASURES:Spin, categorised as: reporting practices that distort the presentation and interpretation of results, c...

journal_title：BMJ (Clinical research ed.)

authors： Bero L,Chiu K,Grundy Q

更新日期：2019-12-18 00:00:00

abstract：OBJECTIVE:To test the hypothesis that radiography of the lumbar spine in patients with low back pain is not associated with improved clinical outcomes or satisfaction with care. DESIGN:Randomised unblinded controlled trial. SETTING:73 general practices in Nottingham, north Nottinghamshire, southern Derbyshire, north ...

journal_title：BMJ (Clinical research ed.)

authors： Kendrick D,Fielding K,Bentley E,Kerslake R,Miller P,Pringle M

更新日期：2001-02-17 00:00:00

abstract：OBJECTIVE:To discover whether the wartime government evacuation of children from London and other population centres to rural districts was associated with any increase in childhood leukaemia. DESIGN:Observational study of mortality from leukaemia among the childhood population of England and Wales in relation to the ...

journal_title：BMJ (Clinical research ed.)

authors： Kinlen LJ,John SM

更新日期：1994-11-05 00:00:00

abstract：OBJECTIVE:To examine whether, according to the conclusions of a 2000 systematic review with meta-analysis on interventions to prevent pain from propofol injection that provided a research agenda to guide further research on the topic, subsequently published trials were more often optimally blinded, reported on children...

journal_title：BMJ (Clinical research ed.)

authors： Habre C,Tramèr MR,Pöpping DM,Elia N

更新日期：2014-08-26 00:00:00

abstract：OBJECTIVE:To quantify an association between acute kidney injury and use of high potency statins versus low potency statins. DESIGN:Retrospective observational analysis of administrative databases, using nine population based cohort studies and meta-analysis. We performed as treated analyses in each database with a ne...

journal_title：BMJ (Clinical research ed.)

authors： Dormuth CR,Hemmelgarn BR,Paterson JM,James MT,Teare GF,Raymond CB,Lafrance JP,Levy A,Garg AX,Ernst P,Canadian Network for Observational Drug Effect Studies.

更新日期：2013-03-18 00:00:00

abstract：OBJECTIVE:To explore geographical and sociodemographic factors associated with variation in equity in access to total hip and knee replacement surgery. DESIGN:Combining small area estimates of need and provision to explore equity in access to care. SETTING:English census wards. SUBJECTS:Patients throughout England w...

journal_title：BMJ (Clinical research ed.)

authors： Judge A,Welton NJ,Sandhu J,Ben-Shlomo Y

更新日期：2010-08-11 00:00:00

abstract：OBJECTIVE:To assess the risk of pulmonary embolism, ischaemic stroke, and myocardial infarction associated with combined oral contraceptives according to dose of oestrogen (ethinylestradiol) and progestogen. DESIGN:Observational cohort study. SETTING:Data from the French national health insurance database linked with...

journal_title：BMJ (Clinical research ed.)

authors： Weill A,Dalichampt M,Raguideau F,Ricordeau P,Blotière PO,Rudant J,Alla F,Zureik M

更新日期：2016-05-10 00:00:00