Palmitoyl Protein Thioesterase 1 Is Essential for Myogenic Autophagy of C2C12 Skeletal Myoblast.

abstract：:Blidingia sp. is a green alga that has spread rapidly in Subei Shoal, China. To explore the potential beneficial effects of Blidingia sp., we investigated the anti-inflammatory activity of its water-methanol extract of Blidingia sp. in a mouse model of lipopolysaccharide (LPS)-induced intestinal inflammation. The resu...

journal_title：Frontiers in physiology

authors： Song W,Li Y,Zhang X,Wang Z

更新日期：2019-06-25 00:00:00

abstract：:The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders. In brief, the sliding movement of fluorescence-labeled actin filaments on myosin motor proteins is recorded, and the sliding velocity ...

journal_title：Frontiers in physiology

authors： Bopp N,Scheid LM,Fink RHA,Rohr K

更新日期：2019-03-27 00:00:00

abstract：:Background: Molting is a crucial physiological behavior during arthropod growth. In the past few years, molting as well as chitin biosynthesis triggered by molting, is subject to regulation by miRNAs. However, how many miRNAs are involved in insect molting at the genome-wide level remains unknown. Results: We deeply s...

journal_title：Frontiers in physiology

authors： Chen J,Li TC,Pang R,Yue XZ,Hu J,Zhang WQ

更新日期：2018-12-20 00:00:00

abstract：:Percutaneous edge-to-edge mitral valve (MV) repair using MitraClip has been recently established as a treatment option for patients with heart failure and functional mitral regurgitation (MR), which significantly expands the number of patients that can be treated with this device. This study aimed to quantify the morp...

journal_title：Frontiers in physiology

authors： Caballero A,Mao W,McKay R,Hahn RT,Sun W

更新日期：2020-05-07 00:00:00

abstract：:The earliest humans relied on large quantities of metabolic energy from the oxidation of fatty acids to develop larger brains and bodies, prevent and reduce disease risk, extend longevity, in addition to other benefits. This was enabled through the consumption of a high fat and low-carbohydrate diet (LCD). Increased f...

journal_title：Frontiers in physiology

authors： Maffetone P,Laursen PB

更新日期：2020-04-02 00:00:00

abstract：:Although interest in several areas of cephalopod research has emerged over the last decades (e.g., neurobiology, aquaculture, genetics, and welfare), especially following their 2010 inclusion in the EU Directive on the use of animals for experimental purposes, knowledge regarding the parasites of cephalopods is lackin...

journal_title：Frontiers in physiology

authors： Roumbedakis K,Drábková M,Tyml T,di Cristo C

更新日期：2018-11-20 00:00:00

abstract：:Previous studies report greater activation in the cortical motor network in controlling eccentric contraction (EC) than concentric contraction (CC) of human skeletal muscles despite lower activation level of the muscle associated with EC. It is unknown, however, whether the strength of functional coupling between the ...

journal_title：Frontiers in physiology

authors： Yao WX,Jiang Z,Li J,Jiang C,Franlin CG,Lancaster JL,Huang Y,Yue GH

更新日期：2016-11-15 00:00:00

abstract：:We examined how systemic blockade of type 1 angiotensin (AT(1)-) receptors affects reflex control of the circulation and the kidney. In conscious rabbits, the effects of candesartan on responses of systemic and renal hemodynamics and renal excretory function to acute hypoxia, mild hemorrhage, and plasma volume expansi...

journal_title：Frontiers in physiology

authors： Xu TB,Eppel GA,Head GA,Evans RG

更新日期：2011-07-19 00:00:00

abstract：:The harbor porpoise is one of the smallest and most widely spread of all toothed whales. They are found abundantly in coastal waters all around the northern hemisphere. They are among the 11 species known to use high frequency sonar of relative narrow bandwidth. Their narrow biosonar beam helps isolate echoes from pre...

journal_title：Frontiers in physiology

authors： Miller LA,Wahlberg M

更新日期：2013-04-15 00:00:00

abstract：:Background: Although endothelial cell protein C receptor (EPCR) gene Ser219Gly polymorphism has been associated with venous thromboembolism (VTE) susceptibility, no clear consensus has yet been reached. Objective and methods: A meta-analysis of 9,494 subjects from 13 individual studies was conducted to better elucidat...

journal_title：Frontiers in physiology

authors： Li YY,Wu JJ,Yang XX,Geng HY,Gong G,Kim HJ

更新日期：2017-05-26 00:00:00

abstract：:The Pacific white shrimp (Litopenaeus vannamei), a euryhaline penaeid species, can tolerate a wide range of salinities, but little is known on its strategies to cope with low salinity fluctuations from the aspect of lipidomics. Thus, in this study, L. vannamei were grown in two different salinities [3 and 30‰ (control...

journal_title：Frontiers in physiology

authors： Huang M,Dong Y,Zhang Y,Chen Q,Xie J,Xu C,Zhao Q,Li E

更新日期：2019-08-23 00:00:00

abstract：:Background: Understanding the microscopic dynamics of the beating heart has been challenging due to the technical nature of imaging with micrometer resolution while the heart moves. The development of multiphoton microscopy has made in vivo, cell-resolved measurements of calcium dynamics and vascular function possible...

journal_title：Frontiers in physiology

authors： Jones JS,Small DM,Nishimura N

更新日期：2018-07-31 00:00:00

abstract：:About 14% of veterans who suffer from Gulf war illness (GWI) complain of some form of gastrointestinal disorder but with no significant markers of clinical pathology. Our previous studies have shown that exposure to GW chemicals resulted in altered microbiome which was associated with damage associated molecular patte...

journal_title：Frontiers in physiology

authors： Kimono D,Sarkar S,Albadrani M,Seth R,Bose D,Mondal A,Li Y,Kar AN,Nagarkatti M,Nagarkatti P,Sullivan K,Janulewicz P,Lasley S,Horner R,Klimas N,Chatterjee S

更新日期：2019-10-14 00:00:00

abstract：Purpose:This study aimed to evaluate effects of remote ischemic preconditioning (RIPC) on myocardial injury in patients undergoing off-pump coronary artery bypass graft surgery (OPCABG). Methods:Sixty-five patients scheduled for the OPCABG were randomly assigned to control (n = 32) or RIPC group (n = 33). All patients...

journal_title：Frontiers in physiology

authors： Wang H,Lyu Y,Liao Q,Jin L,Xu L,Hu Y,Yu Y,Guo K

更新日期：2019-04-29 00:00:00

abstract：:Introduction: Endothelial progenitor cells (EPCs) display a unique ability to promote angiogenesis and restore endothelial function in injured blood vessels. NADPH oxidase 4 (NOX4)-derived hydrogen peroxide (H2O2) serves as a signaling molecule and promotes endothelial cell proliferation and migration as well as prote...

journal_title：Frontiers in physiology

authors： Hakami NY,Ranjan AK,Hardikar AA,Dusting GJ,Peshavariya HM

更新日期：2017-03-23 00:00:00

abstract：:With the advent of high-throughput technologies, the field of systems biology has amassed an abundance of "omics" data, quantifying thousands of cellular components across a variety of scales, ranging from mRNA transcript levels to metabolite quantities. Methods are needed to not only integrate this omics data but to ...

journal_title：Frontiers in physiology

authors： Blazier AS,Papin JA

更新日期：2012-08-06 00:00:00

abstract：:Hyperbilirubinemia (HB) occurs in 90% of preterm newborns. Moderate HB can induce acute neurological disorders while severe HB has been linked to a higher incidence of apneas of prematurity. The present study aimed to test the hypothesis that even moderate HB disrupts cardiorespiratory control in preterm lambs. Two gr...

journal_title：Frontiers in physiology

authors： Specq ML,Bourgoin-Heck M,Samson N,Corbin F,Gestreau C,Richer M,Kadhim H,Praud JP

更新日期：2016-09-30 00:00:00

abstract：:Fatigue is one of the most debilitating symptoms of multiple sclerosis (MS), and the underlying mechanisms are poorly understood. When exposed to a physical or cognitive challenge, individuals with MS tend to exhibit greater declines in task performance (performance fatigability) and increased levels of self-reported ...

journal_title：Frontiers in physiology

authors： Gould JR,Reineberg AE,Cleland BT,Knoblauch KE,Clinton GK,Banich MT,Corboy JR,Enoka RM

更新日期：2018-10-17 00:00:00

abstract：:The Proline, Glutamate, Valine and Lysine-rich (PEVK) region of titin constitutes an entropic spring that provides passive tension to striated muscle. To study the functional and structural repercussions of a small reduction in the size of the PEVK region, we investigated skeletal muscles of a mouse with the constitut...

journal_title：Frontiers in physiology

authors： van der Pijl RJ,Hudson B,Granzier-Nakajima T,Li F,Knottnerus AM,Smith J,Chung CS,Gotthardt M,Granzier HL,Ottenheijm CAC

更新日期：2020-05-29 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle. Mitochondrial dysfunction is a well-known pathological feature of DMD. However, whether mitochondrial dysfunction occurs before muscle fiber damage in DMD pathology is not well known. Furthermore, the impact upon heterozygous femal...

journal_title：Frontiers in physiology

authors： Moore TM,Lin AJ,Strumwasser AR,Cory K,Whitney K,Ho T,Ho T,Lee JL,Rucker DH,Nguyen CQ,Yackly A,Mahata SK,Wanagat J,Stiles L,Turcotte LP,Crosbie RH,Zhou Z

更新日期：2020-06-19 00:00:00

abstract：:To excrete body nitrogen waste and regulate electrolyte and fluid balance, the kidney has developed into an energy factory with only second to the heart in mitochondrial content in the body to meet the high-energy demand and regulate homeostasis. Energy supply from the renal mitochondria majorly depends on lipid metab...

journal_title：Frontiers in physiology

authors： Lin PH,Duann P

更新日期：2020-09-03 00:00:00

abstract：:We examined structural properties of the marine mammal respiratory system, and tested Scholander's hypothesis that the chest is highly compliant by measuring the mechanical properties of the respiratory system in five species of pinniped under anesthesia (Pacific harbor seal, Phoca vitulina; northern elephant seal, Mi...

journal_title：Frontiers in physiology

authors： Fahlman A,Loring SH,Johnson SP,Haulena M,Trites AW,Fravel VA,Van Bonn WG

更新日期：2014-11-10 00:00:00

abstract：:A recent experiment proves the therapeutic effect of arm-in-arm walking, showing that if an aged participant walks in close synchrony with a young companion, the complexity matching effect results in the restoration of complexity in the former. A clear manifestation of complexity restoration is a perfect synchronizati...

journal_title：Frontiers in physiology

authors： Mahmoodi K,West BJ,Grigolini P

更新日期：2020-09-30 00:00:00

abstract：:Blood pressure regulation is a prime example of homeostatic regulation. However, some characteristics of the cardiovascular system better match a non-linear self-organized system than a homeostatic one. To determine whether blood pressure regulation is self-organized, we repeated the seminal demonstration of self-orga...

journal_title：Frontiers in physiology

authors： Fortrat JO,Levrard T,Courcinous S,Victor J

更新日期：2016-03-31 00:00:00

abstract：:Being the central metabolic organ of vertebrates, the liver possesses the largest repertoire of metabolic enzymes among all tissues and organs. Almost all metabolic pathways are resident in the parenchymal cell, hepatocyte, but the pathway capacities may largely differ depending on the localization of hepatocytes with...

journal_title：Frontiers in physiology

authors： Berndt N,Holzhütter HG

更新日期：2018-12-12 00:00:00

abstract：:A moderate hypoxic stimulus is considered a promising therapeutic modality for several pathological states including obesity. There is scientific evidence suggesting that when hypoxia and physical activity are combined, they could provide benefits for the obese population. The aim of the present study was to investiga...

journal_title：Frontiers in physiology

authors： Camacho-Cardenosa A,Camacho-Cardenosa M,Burtscher M,Martínez-Guardado I,Timon R,Brazo-Sayavera J,Olcina G

更新日期：2018-02-07 00:00:00

abstract：:In our digitized society, advanced information and communication technology and highly interactive work environments impose high demands on cognitive capacity. Optimal workload conditions are important for assuring employee's health and safety of other persons. This is particularly relevant in safety-critical occupati...

journal_title：Frontiers in physiology

authors： Radüntz T,Fürstenau N,Mühlhausen T,Meffert B

更新日期：2020-04-21 00:00:00

abstract：:Recently, we reported that Dahl salt-sensitive leptin receptor mutant (SSLepRmutant) rats exhibit dyslipidemia and renal lipid accumulation independent of hyperglycemia that progresses to chronic kidney disease (CKD). Therefore, in the current study, we examined the effects of gemfibrozil, a lipid-lowering drug (200 m...

journal_title：Frontiers in physiology

authors： Shields CA,Poudel B,McPherson KC,Brown AK,Ekperikpe US,Browning E,Sutton L,Cornelius DC,Williams JM

更新日期：2020-09-18 00:00:00

abstract：:Aim: To investigate whether housing temperature influences rat adiposity, and the extent it is modified by diet and/or pregnancy. Housing temperature impacts on brown adipose tissue, that possess a unique uncoupling protein (UCP) 1, which, when activated by reduced ambient temperature, enables rapid heat generation. M...

journal_title：Frontiers in physiology

authors： Albustanji L,Perez GS,AlHarethi E,Aldiss P,Bloor I,Barreto-Medeiros JM,Budge H,Symonds ME,Dellschaft N

更新日期：2019-03-06 00:00:00

abstract：:Background: In an aging population, regular physical activity (PA) and exercise have been recognized as important factors in maintaining physical function and thereby preventing loss of independence and disability. However, (older) adults spent the majority of their day sedentary and therefore insight into the consequ...

journal_title：Frontiers in physiology

authors： van der Velde JHPM,Savelberg HHCM,van der Berg JD,Sep SJS,van der Kallen CJH,Dagnelie PC,Schram MT,Henry RMA,Reijven PLM,van Geel TACM,Stehouwer CDA,Koster A,Schaper NC

更新日期：2017-04-25 00:00:00