Data-Driven Discovery of Predictors of Virtual Reality Safety and Sense of Presence for Children With Autism Spectrum Disorder: A Pilot Study.

Abstract:

:Virtual reality (VR) offers children with autism spectrum disorder (ASD) an inexpensive and motivating medium to learn and practice skills in a personalized, controlled, and safe setting; however, outcomes of VR interventions can vary widely. In particular, there is a need to understand the predictors of VR experience in children with ASD to inform the design of these interventions. To address this gap, a sample of children with ASD (n=35, mean age: 13.0 ± 2.6 years; 10 female) participated in a pilot study involving an immersive VR experience delivered through a head-mounted display. A data-driven approach was used to discover predictors of VR safety and sense of presence among a range of demographic and phenotypic user characteristics. Our results suggest that IQ may be a key predictor of VR sense of presence and that anxiety may modify the association between IQ and sense of presence. In particular, in low-anxiety participants, IQ was linearly related to experienced spatial presence and engagement, whereas, in high-anxiety participants, this association followed a quadratic form. The results of this pilot study, when replicated in larger samples, will inform the design of future studies on VR interventions for children with ASD.

journal_name

Front Psychiatry

journal_title

Frontiers in psychiatry

authors

Malihi M,Nguyen J,Cardy RE,Eldon S,Petta C,Kushki A

doi

10.3389/fpsyt.2020.00669

subject

Has Abstract

pub_date

2020-08-04 00:00:00

pages

669

issn

1664-0640

journal_volume

11

pub_type

杂志文章
  • Efficacy of "Attachment-Based Compassion Therapy" in the Treatment of Fibromyalgia: A Randomized Controlled Trial.

    abstract:Objective:There is a growing interest in evaluating the effectiveness of compassion interventions for treating psychological disorders. The present study evaluated the effectiveness of "attachment-based compassion therapy" (ABCT) in the treatment of fibromyalgia (FM), and the role of psychological flexibility as a medi...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2017.00307

    authors: Montero-Marín J,Navarro-Gil M,Puebla-Guedea M,Luciano JV,Van Gordon W,Shonin E,García-Campayo J

    更新日期:2018-01-16 00:00:00

  • Classical Conditioning as a Distinct Mechanism of Placebo Effects.

    abstract::Classical conditioning was suggested as a mechanism of placebo effects in the 1950s. It was then challenged by response expectancy theory, which proposed that classical conditioning is just one of the means by which expectancies are acquired and changed. According to that account, placebo effects induced by classical ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00449

    authors: Bąbel P

    更新日期:2019-06-25 00:00:00

  • Hippocampal Functional Connectivity Mediates the Impact of Acceptance on Posttraumatic Stress Symptom Severity.

    abstract::Investigation in posttraumatic stress disorder (PTSD) shows a negative association between patients' degrees of acceptance (the willingness to face unwanted private experiences while pursuing one's values and goals) and those of clinical symptom severity, suggesting that experiential acceptance is a protective factor ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00753

    authors: Jung WH,Kim NH

    更新日期:2020-07-30 00:00:00

  • Analysis of the Deleterious Single-Nucleotide Polymorphisms Associated With Antidepressant Efficacy in Major Depressive Disorder.

    abstract::Major depressive disorder (MDD) is a serious mental disease with negative effects on both mental and physical health of the patient. Currently, antidepressants are among the major ways to ease or treat MDD. However, the existing antidepressants have limited efficacy in treating MDD, with a large fraction of patients e...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00151

    authors: Xin J,Yuan M,Peng Y,Wang J

    更新日期:2020-03-18 00:00:00

  • Internet- and App-Based Stress Intervention for Distance-Learning Students With Depressive Symptoms: Protocol of a Randomized Controlled Trial.

    abstract::Background: Mental disorders are highly prevalent among university students. Distance-learning students are particularly burdened and have limited access to conventional university health services. Interventions for stress are sought after in distance learners and may help increase treatment coverage. Internet-based i...

    journal_title:Frontiers in psychiatry

    pub_type:

    doi:10.3389/fpsyt.2019.00361

    authors: Harrer M,Apolinário-Hagen J,Fritsche L,Drüge M,Krings L,Beck K,Salewski C,Zarski AC,Lehr D,Baumeister H,Ebert DD

    更新日期:2019-05-21 00:00:00

  • Effects of Trazodone on Sleep Quality and Cognitive Function in Arteriosclerotic Cerebral Small Vessel Disease Comorbid With Chronic Insomnia.

    abstract:Background:Chronic insomnia is common in patients with arteriosclerotic cerebral small vessel disease (CSVD) and aggravates the cognitive impairment caused by CSVD. Low-dose trazodone is effective in treating insomnia, but it is unclear whether it can also improve cognitive function in CSVD patients. This study was per...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00620

    authors: Wang J,Liu S,Zhao C,Han H,Chen X,Tao J,Lu Z

    更新日期:2020-06-30 00:00:00

  • Exploring Mental Health Status and Syndrome Patterns Among Young Refugee Children in Germany.

    abstract::Refugee children share a large number of pre-, peri-, and post-migration risk factors, which make them vulnerable for developing mental health concerns. Within the last few years, a large number of families with young children have sought refuge in Germany. However, children's mental health status in Germany is mostly...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00212

    authors: Buchmüller T,Lembcke H,Busch J,Kumsta R,Leyendecker B

    更新日期:2018-05-25 00:00:00

  • Perceived Paternal Involvement, Relationship Satisfaction, Mothers' Mental Health and Parenting Stress: A Multi-Sample Path Analysis.

    abstract::Research has demonstrated the short- and long-term impacts of maternal mental health and well-being on children's emotional and behavioral outcomes. It is thus important to better understand the antecedents of maternal depression and stress. The aim of this study was to determine whether the contribution of perceived ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.578682

    authors: deMontigny F,Gervais C,Pierce T,Lavigne G

    更新日期:2020-11-02 00:00:00

  • Impact of Parenting Style on Clinically Significant Behavioral Problems Among Children Aged 4-11 Years Old After Disaster: A Follow-Up Study of the Great East Japan Earthquake.

    abstract::Objective: The purpose of this study was to investigate the influence of parenting style on children's behavior problems after the Great East Japan Earthquake in 2011. Methods: Participants were children exposed to the 2011 disaster at preschool age (n = 163). Data were collected from August 2012 to March 2013, and fr...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00045

    authors: Miki T,Fujiwara T,Yagi J,Homma H,Mashiko H,Nagao K,Okuyama M

    更新日期:2019-02-19 00:00:00

  • Use of Technology to Promote Child Behavioral Health in the Context of Pediatric Care: A Scoping Review and Applications to Low- and Middle-Income Countries.

    abstract::Background: The burden of mental, neurological, and substance (MNS) disorders is greater in low- and middle-income countries (LMICs). The rapid growth of digital health (i.e., eHealth) approaches offer new solutions for transforming pediatric mental health services and have the potential to address multiple resource a...

    journal_title:Frontiers in psychiatry

    pub_type:

    doi:10.3389/fpsyt.2019.00806

    authors: Huang KY,Lee D,Nakigudde J,Cheng S,Gouley KK,Mann D,Schoenthaler A,Chokshi S,Kisakye EN,Tusiime C,Mendelsohn A

    更新日期:2019-11-13 00:00:00

  • Social Attention in Autism: Neural Sensitivity to Speech Over Background Noise Predicts Encoding of Social Information.

    abstract::Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by lack of attention to social cues in the environment, including speech. Hypersensitivity to sensory stimuli, such as loud noises, is also extremely common in youth with ASD. While a link between sensory hypersensitivity and impaired social...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00343

    authors: Hernandez LM,Green SA,Lawrence KE,Inada M,Liu J,Bookheimer SY,Dapretto M

    更新日期:2020-04-24 00:00:00

  • Anti-inflammatory Effect of Ghrelin in Lymphoblastoid Cell Lines From Children With Autism Spectrum Disorder.

    abstract::The gut hormone ghrelin has been implicated in a variety of functional roles in the central nervous system through the brain-gut axis, one of which is an anti-inflammatory effect. An aberrant brain-gut axis producing immune dysfunction has been implicated in the pathobiology of autism spectrum disorder (ASD), and elev...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00152

    authors: Yamashita Y,Makinodan M,Toritsuka M,Yamauchi T,Ikawa D,Kimoto S,Komori T,Takada R,Kayashima Y,Hamano-Iwasa K,Tsujii M,Matsuzaki H,Kishimoto T

    更新日期:2019-03-26 00:00:00

  • Regional Cerebral Associations Between Psychometric Tests and Imaging Biomarkers in Alzheimer's Disease.

    abstract::Recently, imaging biomarkers have gained importance for the characterization of patients with Alzheimer's disease; however, the relationship between regional biomarker expression and cognitive function remains unclear. In our study, we investigated associations between scores on CERAD neuropsychological assessment bat...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00793

    authors: Hedderich DM,Drost R,Goldhardt O,Ortner M,Müller-Sarnowski F,Diehl-Schmid J,Zimmer C,Förstl H,Yakushev I,Jahn T,Grimmer T

    更新日期:2020-08-13 00:00:00

  • Alteration of Brain Structure With Long-Term Abstinence of Methamphetamine by Voxel-Based Morphometry.

    abstract::Background: A large portion of previous studies that have demonstrated brain gray matter reduction in individuals who use methamphetamine (MA) have focused on short-term abstinence, but few studies have focused on the effects of long-term abstinence of methamphetamine on brain structures. Materials and Methods: Our st...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00722

    authors: Zhang Z,He L,Huang S,Fan L,Li Y,Li P,Zhang J,Liu J,Yang R

    更新日期:2018-12-20 00:00:00

  • The Association of Non-obscene Socially Inappropriate Behavior With Attention-Deficit/Hyperactivity Disorder Symptoms, Conduct Problems, and Risky Decision Making in a Large Sample of Adolescents.

    abstract::Non-obscene socially inappropriate behavior (NOSI) is recognized as part of the tic disorder spectrum but has received little attention from researchers to date. A study in 87 patients with Tourette syndrome showed that comorbid attention-deficit/hyperactivity disorder (ADHD) and conduct disorder were also associated ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00660

    authors: Brandt V,Kerner Auch Koerner J,Palmer-Cooper E

    更新日期:2019-09-13 00:00:00

  • Effect of Aerobic Exercise on Improving Symptoms of Individuals With Schizophrenia: A Single Blinded Randomized Control Study.

    abstract::Introduction: Antipsychotic treatment can improve the symptoms of schizophrenia; however, residual symptoms after antipsychotic treatment are frequent. The effects of exercise on the symptoms of schizophrenic patients under antipsychotic treatment are inconclusive. The aim of this randomized case-control study was to ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2018.00167

    authors: Wang PW,Lin HC,Su CY,Chen MD,Lin KC,Ko CH,Yen CF

    更新日期:2018-05-15 00:00:00

  • Effects of Increasing the Negativity of Implicit Outcome Expectancies on Internet Gaming Impulsivity.

    abstract::Outcome expectancies have been found to play important roles in addictive behaviors. Research has shown that implicit outcome expectancies (OE) were significantly correlated with Internet gaming behaviors among players with Internet gaming disorder (IGD). However, few empirical studies have further examined the relati...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00336

    authors: Hou S,Fang X,Zhou N,Cai P

    更新日期:2020-04-29 00:00:00

  • Empathy in Females With Autism Spectrum Disorder.

    abstract::Objective: Despite the fact that autism spectrum disorder (ASD) is a common psychiatric diagnosis, knowledge about the special behavioral and neurobiological female phenotype is still scarce. The present study aimed to investigate neural correlates of empathy for physical and social pain and to assess the impact of eg...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00428

    authors: Stroth S,Paye L,Kamp-Becker I,Wermter AK,Krach S,Paulus FM,Müller-Pinzler L

    更新日期:2019-06-18 00:00:00

  • Elevated Osteopontin and Interferon Gamma Serum Levels and Increased Neutrophil-to-Lymphocyte Ratio Are Associated With the Severity of Symptoms in Schizophrenia.

    abstract::Inflammation and immune dysregulation could contribute to the pathogenesis of schizophrenia. Osteopontin (OPN) is a cytokine-like glycoprotein involved in inflammation and in modulating immune responses, and it can also directly modify the cytokine expression and survival of microglia. Furthermore, elevated gene expre...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00996

    authors: Kovács MÁ,Tényi T,Kugyelka R,Prenek L,Hau L,Magyar ÉE,Herold R,Balogh P,Simon D

    更新日期:2020-01-23 00:00:00

  • Astrocytic Regulation of Glutamate Transmission in Schizophrenia.

    abstract::According to the glutamate hypothesis of schizophrenia, the abnormality of glutamate transmission induced by hypofunction of NMDA receptors (NMDARs) is causally associated with the positive and negative symptoms of schizophrenia. However, the underlying mechanisms responsible for the changes in glutamate transmission ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2018.00544

    authors: Mei YY,Wu DC,Zhou N

    更新日期:2018-11-06 00:00:00

  • Pharmacological modulation of the short-lasting effects of antagonistic direct current-stimulation over the human motor cortex.

    abstract::Combined administration of transcranial direct current-stimulation (tDCS) with either pergolide (PER) or d-cycloserine (d-CYC) can prolong the excitability-diminishing effects of cathodal, or the excitability enhancing effect of anodal stimulation for up to 24 h poststimulation. However, it remains unclear whether the...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2012.00067

    authors: Chaieb L,Antal A,Terney D,Paulus W

    更新日期:2012-07-05 00:00:00

  • Altered Global Brain Functional Connectivity in Drug-Naive Patients With Obsessive-Compulsive Disorder.

    abstract::Abnormal functional connectivity (FC) within discrete brain networks is involved in the pathophysiology of obsessive-compulsive disorder (OCD) with inconsistent results. In the present study, we investigated the FC patterns of 40 drug-naive patients with OCD and 38 healthy controls (HCs) through an unbiased voxel-wise...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.00098

    authors: Cui G,Ou Y,Chen Y,Lv D,Jia C,Zhong Z,Yang R,Wang Y,Meng X,Cui H,Li C,Sun Z,Wang X,Guo W,Li P

    更新日期:2020-03-03 00:00:00

  • Do manual and voxel-based morphometry measure the same? A proof of concept study.

    abstract::Voxel-based morphometry (VBM) is a commonly used method to study volumetric variations on a whole brain basis. However, it is often criticized for potential confounds, mainly based on imperfect spatial registration. We therefore aimed to evaluate if VBM and "gold standard" manual volumetry are measuring the same effec...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2014.00039

    authors: Focke NK,Trost S,Paulus W,Falkai P,Gruber O

    更新日期:2014-04-08 00:00:00

  • Bibliometric and Visual Analysis of Research on the Links Between the Gut Microbiota and Depression From 1999 to 2019.

    abstract::Background: There is a crucial link between the gut microbiota and the host central nervous system, and the communication between them occurs via a bidirectional pathway termed the "microbiota-gut-brain axis." The gut microbiome in the modern environment has markedly changed in response to environmental factors. These...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.587670

    authors: Zhu X,Hu J,Deng S,Tan Y,Qiu C,Zhang M,Ni X,Lu H,Wang Z,Li L,Chen H,Huang S,Xiao T,Shang D,Wen Y

    更新日期:2021-01-08 00:00:00

  • Clozapine-Induced Pneumonitis: A Case Report.

    abstract::Introduction: Clozapine is the most effective antipsychotic used for treatment resistant schizophrenia and recurrent suicidal behavior in schizophrenia or schizoaffective disorder. However, it has been underutilized due to its adverse reaction profile. Although clozapine is typically associated with neutropenia leadin...

    journal_title:Frontiers in psychiatry

    pub_type:

    doi:10.3389/fpsyt.2020.572102

    authors: Torrico T,Crandall RO,Meza C,Abdijadid S

    更新日期:2020-10-14 00:00:00

  • Using EEG-Guided Basket and Umbrella Trials in Psychiatry: A Precision Medicine Approach for Cognitive Impairment in Schizophrenia.

    abstract::Due to advances over the last several decades, many fields of medicine are moving toward a precision medicine approach where treatments are tailored to nuanced patient factors. While in some disciplines these innovations are commonplace leading to unique biomarker-guided experimental medicine trials, there are no such...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2018.00554

    authors: Joshi YB,Light GA

    更新日期:2018-11-19 00:00:00

  • Current Challenges in Translational and Clinical fMRI and Future Directions.

    abstract::Translational neuroscience is an important field that brings together clinical praxis with neuroscience methods. In this review article, the focus will be on functional neuroimaging (fMRI) and its applicability in clinical fMRI studies. In the light of the "replication crisis," three aspects will be critically discuss...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2019.00924

    authors: Specht K

    更新日期:2020-01-08 00:00:00

  • Overview of substance use disorders and incarceration of african american males.

    abstract::Incarceration affects the lives of many African American men and often leads to poverty, ill health, violence, and a decreased quality of life. There has been an unprecedented increase in incarceration among African American males since 1970. In 2009, the incarceration rate among black males was 6.7 times that of whit...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2012.00098

    authors: Mukku VK,Benson TG,Alam F,Richie WD,Bailey RK

    更新日期:2012-11-12 00:00:00

  • Modeling Trait Anxiety: From Computational Processes to Personality.

    abstract::Computational methods are increasingly being applied to the study of psychiatric disorders. Often, this involves fitting models to the behavior of individuals with subclinical character traits that are known vulnerability factors for the development of psychiatric conditions. Anxiety disorders can be examined with ref...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章,评审

    doi:10.3389/fpsyt.2017.00001

    authors: Raymond JG,Steele JD,Seriès P

    更新日期:2017-01-23 00:00:00

  • Sleep Quality as a Mediator in the Relationship Between Perceived Stress and Job Burnout Among Chinese Nurses: A Structural Equation Modeling Analysis.

    abstract::Background: Job burnout has become an increasing prevailing phenomenon among nurses in both developed and developing countries. There is a paucity of research exploring the relationship between perceived stress (i.e., the level of one's perception or appraisal of stress rather than objective stressful events) and job ...

    journal_title:Frontiers in psychiatry

    pub_type: 杂志文章

    doi:10.3389/fpsyt.2020.566196

    authors: Song Y,Yang F,Sznajder K,Yang X

    更新日期:2020-11-13 00:00:00