Astrocytic Regulation of Glutamate Transmission in Schizophrenia.

abstract：:Alcohol is one of the leading risk factors for global disease burden and overconsumption leads to a wide variety of negative consequences in everyday life. Digital interventions have shown small positive effects in contributing to reductions in problematic use. Specific research on smartphone apps is sparse and the fe...

journal_title：Frontiers in psychiatry

authors： Berman AH,Molander O,Tahir M,Törnblom P,Gajecki M,Sinadinovic K,Andersson C

更新日期：2020-05-27 00:00:00

abstract：:Objective: Patients with schizophrenia exhibit impaired social cognition, especially in the recognition and expression of facial emotions, aspects of communication profoundly interlinked in an embodied approach of cognition. Nevertheless, many training programs have been developed that focus on either of these deficit...

journal_title：Frontiers in psychiatry

authors： Sevos J,Grosselin A,Gauthier M,Carmona F,Gay A,Massoubre C

更新日期：2018-07-23 00:00:00

abstract：:The number of people with dementia worldwide is expected to increase to approximately 1.3 billion in 2050. Almost 90% of patients diagnosed with dementia suffer from behavioral and psychological symptoms of dementia (BPSD). BPSD causes and risk factors are multiple and complex and can be responsible for hospitalizatio...

journal_title：Frontiers in psychiatry

authors： Soares WB,Silvestre IT,Lima AMO,de Almondes KM

更新日期：2020-09-15 00:00:00

abstract：:Objective: We aimed to determine the prevalence of burnout among hospital healthcare workers in Libya during the coronavirus disease (COVID-19) pandemic and civil war. Methods: A cross-sectional study was conducted from April 18 to May 2, 2020 among Libyan healthcare workers. Data on participant characteristics were c...

journal_title：Frontiers in psychiatry

authors： Elhadi M,Msherghi A,Elgzairi M,Alhashimi A,Bouhuwaish A,Biala M,Abuelmeda S,Khel S,Khaled A,Alsoufi A,Elmabrouk A,Alshiteewi FB,Hamed TB,Alhadi B,Alhaddad S,Elhadi A,Zaid A

更新日期：2020-12-11 00:00:00

abstract：:One of the fundamental questions in neuroscience is how brain activity relates to conscious experience. Even though self-consciousness is considered an emergent property of the brain network, a quantum physics-based theory assigns a momentum of consciousness to the single neuron level. In this work, we present a brain...

journal_title：Frontiers in psychiatry

authors： Sánchez-Ramón S,Faure F

更新日期：2020-09-29 00:00:00

abstract：:Butyrylcholinesterase (BChE) efficiently hydrolyzes acetylcholine (ACh) at high concentrations when acetylcholinesterase (AChE) is substrate-inhibited. Recent studies have shown that BChE also has a function that is independent of ACh, but it has not been fully explored. Low BChE expression is accompanied with higher ...

journal_title：Frontiers in psychiatry

authors： Chen S,Lin Z,Tan KL,Chen R,Su W,Zhao H,Tan Q,Tan W

更新日期：2020-09-11 00:00:00

abstract：:Depression has been associated with peripheral inflammatory processes and alterations in cellular immunity. Growing evidence suggests that immunological alterations may neither be necessary nor sufficient to induce depression in general, but seem to be associated with specific features. Using baseline data from the Ou...

journal_title：Frontiers in psychiatry

authors： Euteneuer F,Dannehl K,Del Rey A,Engler H,Schedlowski M,Rief W

更新日期：2017-11-23 00:00:00

abstract：:Magnetic seizure therapy (MST) is a potential alternative to electroconvulsive therapy (ECT), but there is currently a lack of reports about MST in Chinese patients with schizophrenia. Our objective was to investigate the feasibility and acceptability of add-on MST in the treatment of patients with schizophrenia. Eigh...

journal_title：Frontiers in psychiatry

authors： Jiang J,Li Q,Sheng J,Yang F,Cao X,Zhang T,Jia Y,Wang J,Li C

更新日期：2018-05-29 00:00:00

abstract：:Suicide is a serious public health issue worldwide, yet current clinical methods for assessing a person's risk of taking their own life remain unreliable and new methods for assessing suicide risk are being explored. The widespread adoption of electronic health records (EHRs) has opened up new possibilities for epidem...

journal_title：Frontiers in psychiatry

authors： Bittar A,Velupillai S,Downs J,Sedgwick R,Dutta R

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Research has demonstrated a reduction in olfactory functioning in patients with schizophrenia. This research has led to examination of olfactory functioning in other mental disorders, such as depression. There is a great deal of variation in the results generated from such research, and it remains unclear as...

journal_title：Frontiers in psychiatry

authors： Taalman H,Wallace C,Milev R

更新日期：2017-09-28 00:00:00

abstract：:Abnormal amplitude of low-frequency fluctuation has been implicated in heroin addiction. However, previous studies lacked consistency and didn't consider the impact of confounding factors such as methadone and alcohol. Fifty-one heroin-dependent (HD) individuals and 40 healthy controls underwent resting-state function...

journal_title：Frontiers in psychiatry

authors： Luo J,Yang R,Yang W,Duan C,Deng Y,Zhang J,Chen J,Liu J

更新日期：2020-07-03 00:00:00

abstract：:Background: Mental disorders are highly prevalent among university students. Distance-learning students are particularly burdened and have limited access to conventional university health services. Interventions for stress are sought after in distance learners and may help increase treatment coverage. Internet-based i...

journal_title：Frontiers in psychiatry

authors： Harrer M,Apolinário-Hagen J,Fritsche L,Drüge M,Krings L,Beck K,Salewski C,Zarski AC,Lehr D,Baumeister H,Ebert DD

更新日期：2019-05-21 00:00:00

abstract：:Background: Catatonia is a syndrome comprising psychomotor, behavioral, and autonomous symptoms which may occur in the context of severe schizophrenic, affective, and other mental disorders or medical conditions. Treatment options include high dose benzodiazepines (lorazepam) and electroconvulsive therapy (ECT) with s...

journal_title：Frontiers in psychiatry

authors： Zilles D

更新日期：2019-02-27 00:00:00

abstract：:The progress of developing effective interventions against psychiatric disorders has been limited due to a lack of understanding of the underlying cellular and functional mechanisms. Recent research findings focused on exploring novel causes of psychiatric disorders have highlighted the importance of the axonal initia...

journal_title：Frontiers in psychiatry

authors： Hsu WC,Nilsson CL,Laezza F

更新日期：2014-08-21 00:00:00

abstract：Objectives:Many studies reported structural brain changes in patients with alcohol dependence (PADs). However, no studies identified structural correlates of apathy that might aggravate alcohol misuse. Here, we explored regional differences in cortical thickness in PADs relative to healthy controls (HCs), and examined ...

journal_title：Frontiers in psychiatry

authors： Yang K,Yang Q,Niu Y,Fan F,Chen S,Luo X,Tan S,Wang Z,Tong J,Yang F,Le TM,Li CR,Tan Y

更新日期：2020-05-05 00:00:00

abstract：:Prenatal infections have been linked to the development of schizophrenia (SCZ) and other neurodevelopmental disorders in the offspring, and work in animal models indicates that this is to occur through the maternal inflammatory response triggered by infection. Several studies in animal models demonstrated that acute i...

journal_title：Frontiers in psychiatry

authors： Aguilar-Valles A,Rodrigue B,Matta-Camacho E

更新日期：2020-08-21 00:00:00

abstract：:Background: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for psychiatric disorders, including major depressive disorder (MDD). Bacterial transplantation from MDD patients to rodents produces depression-like behaviors. In humans, case-control studies have exa...

journal_title：Frontiers in psychiatry

authors： Cheung SG,Goldenthal AR,Uhlemann AC,Mann JJ,Miller JM,Sublette ME

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:Several lines of evidence implicate dysfunctional neuronal plasticity in the pathophysiology of schizophrenia (SCZ). Aberrant glutamatergic and gamma amino--butyric acid neurotransmission are thought to underlie core cognitive deficits and negative symptoms of SCZ. Non-invasive brain stimulation (NIBS) allow...

journal_title：Frontiers in psychiatry

authors： Bhandari A,Voineskos D,Daskalakis ZJ,Rajji TK,Blumberger DM

更新日期：2016-03-29 00:00:00

abstract：:We use auditory verbal hallucinations (AVH) to illustrate the challenges in defining and assessing target engagement in the context of transcranial direct current stimulation (tDCS) for psychiatric disorders. We defined the target network as the cluster of regions of interest (ROIs) that are consistently implicated in...

journal_title：Frontiers in psychiatry

authors： Lee WH,Kennedy NI,Bikson M,Frangou S

更新日期：2018-02-22 00:00:00

abstract：Objective:Insomnia is associated with suicidality, although the mechanisms of this association are unclear. This study sought to replicate previous findings showing that insomnia symptoms but not sleep duration are associated with frequency of suicidal ideation in adults. We further investigated whether depression or s...

journal_title：Frontiers in psychiatry

authors： Simmons Z,Erickson LD,Hedges D,Kay DB

更新日期：2020-09-18 00:00:00

abstract：:Tourette syndrome (TS) is a developmental neuropsychiatric disorder with onset during childhood. Because of its complex spectrum of phenotypes, the underlying pathophysiology of TS is still unclear. Resting-state functional magnetic resonance imaging demonstrated aberrant spontaneous neural synchronization in conventi...

journal_title：Frontiers in psychiatry

authors： Lou YT,Li XL,Wang Y,Ji GJ,Zang YF,Wang J,Feng JH

更新日期：2020-12-17 00:00:00

abstract：:Elevation of the blood ethanol concentration (BEC) to > 80 mg/dL (17.4 mM) after binge drinking enhances inflammation in brain and neuroimmune signaling pathways. Morphine abuse is frequently linked to excessive drinking. Morphine exerts its actions mainly via the seven transmembrane G-protein-coupled mu opioid recept...

journal_title：Frontiers in psychiatry

authors： Chang SL,Huang W,Han H,Sariyer IK

更新日期：2019-01-22 00:00:00

abstract：:With the opioid crisis in North America, opioid addiction has come in the spotlight and reveals the weakness of the current treatments. Two main opioid substitution therapies (OST) exist: buprenorphine and methadone. These two molecules are mu opioid receptor agonists but with different pharmacodynamic and pharmacokin...

journal_title：Frontiers in psychiatry

authors： Noble F,Marie N

更新日期：2019-01-18 00:00:00

abstract：:Background: Young adults regularly using cannabis represent a uniquely vulnerable yet heterogeneous cohort. Few studies have examined user profiles using cannabis use motives and expectations. The association between user profiles and psychosocial functioning among only regular users remains unexplored. This explorati...

journal_title：Frontiers in psychiatry

authors： Amiet D,Youssef GJ,Hagg LJ,Lorenzetti V,Parkes L,Solowij N,Yücel M

更新日期：2020-12-15 00:00:00

abstract：:This study examined parental recognition of bullying victimization and associated factors among evacuated children after the 2011 Fukushima Daiichi Nuclear Power Plant accident, using a 3-year follow-up data (wave 1: January 2012; wave 2: January 2013; wave 3: February 2014). The sample included the caregivers of 2,61...

journal_title：Frontiers in psychiatry

authors： Oe M,Maeda M,Ohira T,Itagaki S,Harigane M,Suzuki Y,Yabe H,Yasumura S,Kamiya K,Ohto H

更新日期：2019-05-03 00:00:00

abstract：:The high rate of comorbidity between insomnia and anxiety disorders have been confirmed by previous studies. However, the underlying neurobiological correlates of the relationship between insomnia and anxiety disorders are largely unknown. The aim of the present study was to investigate the effect of insomnia on corti...

journal_title：Frontiers in psychiatry

authors： Huang Z,Zhan S,Chen C,Li N,Ding Y,Hou Y,Wang L,Wang Y

更新日期：2019-01-10 00:00:00

abstract：:While psychological treatments have been shown to be effective in treating psychiatric disorders, the mechanism of their therapeutic effect is less well understood. An improved mechanistic understanding of psychiatric disorders and their treatments would enable refinement of existing interventions, and more targeted i...

journal_title：Frontiers in psychiatry

authors： Griffin B,Saunders KEA

更新日期：2020-01-17 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fpsyt.2020.00202.]. ...

journal_title：Frontiers in psychiatry

authors： Martin R,Benoit JP,Moro MR,Benoit L

更新日期：2020-04-23 00:00:00

abstract：:Background: People who receive involuntary treatment are some of the most vulnerable in psychiatric services. They are more likely to have poorer social and clinical outcomes and to be disillusioned with and disengaged from care. Research indicates that patients' experience in the first week of involuntary treatment i...

journal_title：Frontiers in psychiatry

authors： Burn E,Conneely M,Leverton M,Giacco D

更新日期：2019-07-04 00:00:00

abstract：:The evolution of the contemporary Therapeutic Community (TC) for addictions over the past 50 years may be characterized as a movement from the marginal to the mainstream of substance abuse treatment and human services. TCs currently serve a wide array of clients and their diverse problems; through advances in research...

journal_title：Frontiers in psychiatry

authors： De Leon G,Unterrainer HF

更新日期：2020-08-06 00:00:00