Ginsenoside Rg1 Performs Anti-Aging Functions by Suppressing Mitochondrial Pathway-Mediated Apoptosis and Activating Sirtuin 3 (SIRT3)/Superoxide Dismutase 2 (SOD2) Pathway in Sca-1⁺ HSC/HPC Cells of an Aging Rat Model.

abstract：BACKGROUND:Tumor growth in multiple myeloma (MM) is regulated by the cytokine networks which are produced by myeloma cells and the microenvironment of the bone marrow. Interleukin-17 (IL-17) is implicated in the increased angiogenesis in the bone marrow of MM. Recent studies reported elevated levels of interleukin 17A ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lemancewicz D,Bolkun L,Jablonska E,Czeczuga-Semeniuk E,Kostur A,Kloczko J,Dzieciol J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Giardiasis is caused by the intestinal protozoan parasite Giardia duodenalis (synonyms: G. lamblia, G. intestinalis), which is one of the most frequent parasites that infect Turkish children. However, molecular characterization of G. duodenalis in Turkey is relatively scarce. The present work aimed at genoty...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tamer GS,Kasap M,Er DK

更新日期：2015-02-18 00:00:00

abstract：BACKGROUND:Psychological disturbances are frequent in Crohn's disease (CD) patients. However, epidemiological studies of non-western CD populations are limited and may be confounded by genetic and disease-related influences. The aim of this study was to assess the prevalence and risk factors for depression and symptoms...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Brandi MT,Ribeiro MS,Chebli LA,Franco MB,Pinto AL,Gaburri PD,Zanini A,Chebli JM

更新日期：2009-08-01 00:00:00

abstract：:Febrile seizures are a common occurrence in young children with incidence rates varying from 3-14%, depending on the geographic region. Studies have suggested that an elevated temperature is a factor in their development, though other factors may synergistically lower the seizure threshold. While it is recognized that...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hoption Cann SA

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:The aim of the study was to compare a computer assessment of carotid plaques with the quantity and distribution of inflammatory cells in the plaques and to find correlation with the incidence of cerebral stroke. MATERIAL/METHODS:The material consisted of 20 carotid plaques causing stenoses of internal carot...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Falkowski A,Parafiniuk M,Poncyljusz W,Kaczmarczyk M,Wilk G

更新日期：2007-05-01 00:00:00

abstract：:BACKGROUND This study aimed to investigate the role of miRNA-339-5p in pancreatic cancer cell invasion and migration. MATERIAL AND METHODS The differences between exosomal miRNAs of PANC02 and PANC02-H7 were studied by microarray analysis. We measured miRNA-339-5p expression in different groups; differences in cell in...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yu Z,Zhao S,Wang L,Wang J,Zhou J

更新日期：2019-10-07 00:00:00

abstract：:BACKGROUND Gliomas are the most common primary tumors of the brain and spinal cord. The tumor microenvironment (TME) is the cellular environment in which tumors exist. This study aimed to identify the role of the TME and the effects of genes involved in the TME of malignant glioma. MATERIAL AND METHODS The ESTIMATE al...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li Y,Deng G,Qi Y,Zhang H,Gao L,Jiang H,Ye Z,Liu B,Chen Q

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Peroxidases are widely distributed and have been isolated from many higher-order plants, animal tissues, yeast and microorganisms. During measurements of peroxidase activities in samples of human plasma, we noticed the presence of a compound in the plasma which was interfering with the peroxidase assay. In t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Padiglia A,Medda R,Longu S,Pedersen JZ,Floris G

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The past 100 years has revealed a controversial history around the menstrual and contraceptive management of women with intellectual disability in residential care settings. The present study was conducted to examine the trends of contraceptive methods for females with intellectual disability in residential ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Morad M,Kandel I,Merrick J

更新日期：2009-06-01 00:00:00

abstract：:BACKGROUND In an atherosclerotic artery wall, monocyte-derived macrophages are the principal mediators that respond to pathogens and inflammation. The present study aimed to investigate potential genetic changes in gene expression between normal tissue-resident macrophages and atherosclerotic macrophages in the human ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang W,Zhang K,Zhang H,Li M,Zhao Y,Wang B,Xin W,Yang W,Zhang J,Yue S,Yang X

更新日期：2019-12-25 00:00:00

abstract：:BACKGROUND Traditional diagnostic methods for tuberculosis (TB) cannot be reliably applied to tuberculous pleurisy. Therefore, this prospective, randomized, controlled trial was performed to compare the diagnostic sensitivity and safety of ultrasound-guided cutting-needle pleural biopsy versus thoracoscopic pleural bi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhou X,Jiang P,Huan X,Li W,Chen Y,Gao H,Qi X,Wu J,Wang X,Ou Y,Jia X

更新日期：2018-10-10 00:00:00

abstract：BACKGROUND:Despite high efficiency of magnetic resonance (MR) imaging in degenerative disease of lumbar spine (DDLS), in many cases its appearance is ambiguous or not compatible with clinical findings. Therefore, different new techniques have been proposed to improve the quality of MR images. One of them is CBASS (Comp...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Maksymowicz H,Sasiadek M,Dusza B,Filarski J

更新日期：2004-06-01 00:00:00

abstract：:BACKGROUND Er-Miao-San (EMS) is used in traditional Chinese medicine. This study aimed to investigate the effect of different elution fractions of EMS on acute inflammation induced by carrageenan in the rat paw and the possible mechanisms of action. MATERIAL AND METHODS Different aqueous fractions of EMS added to an A...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dai X,Ding M,Zhang W,Xuan Z,Liang J,Yang D,Zhang Q,Su B,Zhu H,Jia X

更新日期：2019-10-23 00:00:00

abstract：:BACKGROUND Long non-coding RNAs (lncRNAs) have been implicated in various human cancer types. However, the underlying mechanisms involved in hepatocellular carcinoma (HCC) progression remain poorly understood. MATERIAL AND METHODS In this study, lncRNA array was used to identify HCC related lncRNAs. RNA immunoprecipit...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li O,Li Z,Tang Q,Li Y,Yuan S,Shen Y,Zhang Z,Li N,Chu K,Lei G

更新日期：2018-11-25 00:00:00

abstract：BACKGROUND:This study presents a systematic analysis of atherothrombotic lesions taken by percutaneous atherectomy and post mortem examination from coronary arteries, in order to identify: a) the topographic occurrence of fibrinogen and smooth muscle cells (SMCs), b) their independent expression in stable and unstable ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Loukas M,Dabrowski M,Wagner T,Walczak E,Witkowski A,Ruzyłło W

更新日期：2002-04-01 00:00:00

abstract：:BACKGROUND This population study aimed to investigate the demographic and clinical characteristics and outcome of cases of coronavirus disease 2019 in Lu'an City, China between January 22, 2020 and February 18, 2020 identified from the China Information System for Disease Control and Prevention (CISDCP). MATERIAL AND ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jiang Z,Sun J,Li X,Lyu Y

更新日期：2020-08-14 00:00:00

abstract：BACKGROUND:The aim of this study was to analyze the effects of obesity and leptin levels on patients with migraine, and to observe the change of leptin levels in migraineurs. MATERIAL AND METHODS:We enrolled 52 migraine patients from the Headache Clinic in Shandong Provincial Hospital into a randomized controlled tria...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ligong Z,Jinjin Q,Chunfu C,Congcong L,Xiaojun D

更新日期：2015-10-28 00:00:00

abstract：BACKGROUND:Up to now there have been few reports about hematological alterations induced by Giardia lamblia infection. The aim of this study was to evaluate the effects of giardiasis treatment on hematological indices in children in the Khuzestan area by comparing these indices before and after treatment with metronida...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Monajemzadeh SM,Monajemzadeh M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Interstitial irradiation therapy using radionuclides is a slow and continual process in which the effect is exerted gradually, thus improvement of the hypoxic status of the tumor will also take a long time. It has been known that carbogen delivery of 5-15 min increases tumor oxygenation. However, the long-te...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhan HW,Liu HB,Bao CK,Ye XJ,Zhang H,He GQ

更新日期：2010-01-01 00:00:00

abstract：:BACKGROUND Serum hepatitis B virus (HBV) DNA and hepatitis B e antigen (HBeAg) liver function in patients with chronic hepatitis B (CHB) are significantly associated. A comparison of clinical significance of fecal HBV DNA and serum HBV DNA has not yet been reported. MATERIAL AND METHODS Stool and serum samples were co...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zheng JS,Chen MM,Yang HF,Zhou XT,Liu YY,Li JB

更新日期：2015-12-09 00:00:00

abstract：:BACKGROUND Endometriosis is a common gynecologic disorder with enigmatic etiopathogenesis and is characterized by tumor-like biological behaviors. Recently, circular RNAs (circRNAs) have attracted considerable attention because they exert very important functions in the progression of human cancers. However, little is...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang M,Ren C,Xiao Y,Xia X,Fang X

更新日期：2018-12-19 00:00:00

abstract：:BACKGROUND The fast pace of life, promoting fast food consumption and low physical activity, has resulted in obesity and/or diabetes as being serious social problems. The aim of the present study was to evaluate concentrations of selected adipokines (leptin, adiponectin, resistin, and visfatin) and to assess the lepti...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Kocot J,Dziemidok P,Kiełczykowska M,Hordyjewska A,Szcześniak G,Musik I

更新日期：2017-10-19 00:00:00

abstract：:BACKGROUND The objective of the present study was to identify the association between miR-15a-5p and CDKN2B, and their roles in regulating the development of abdominal aortic aneurysm (AAA). MATERIAL AND METHODS We searched the miRNA database online (www.mirdb.org) and used a luciferase reporter assay system to study ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Gao P,Si J,Yang B,Yu J

更新日期：2017-02-18 00:00:00

abstract：:BACKGROUND Liver cancer is the third leading cause of tumor-related deaths worldwide. Stomatin-like protein 2 (STOML2) is obviously upregulated in various tumors. In this study, we explored the potential roles and mechanisms of si-STOML2 in the migration and invasion of human hepatoma LM3 cells. MATERIAL AND METHODS T...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu W,Li W,Geng Q,Wang X,Sun W,Jiang H,Pu X

更新日期：2018-10-25 00:00:00

abstract：:BACKGROUND The aim of this study was to discuss the possible roles and clinical value of 2 circRNAs (hsa_circ_0049224 and has_circ_0049220) in SLE patients. MATERIAL AND METHODS Reverse-transcription real-time polymerase chain reaction (RT-PCR) was conducted to detect the expressions of hsa_circ_0049224, has_circ_0049...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang C,Huang J,Chen Y,Shi W

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:The placebo effect describes the mind-body process of altering the body's physiological state as well as the brain's neurological state. Catalyzed by the mind's believing in a certain drug, ritual, and/or treatment, it generally refers to the phenomenon of an ill individual recovering to health. Subsequent t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Slingsby BT

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:It is well known that peroxisome proliferator-activated receptor gamma (PPARγ), a ligand-activated transcription factor, plays a protective role in anti-inflammatory responses in both acute and chronic central nerve system (CNS) insults. Emerging evidence in rats suggests that vagus nerve stimulation (VNS), ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jiang Y,Li L,Liu B,Zhang Y,Chen Q,Li C

更新日期：2015-01-21 00:00:00

abstract：:BACKGROUND Inflammatory responses in utero and in neonates have been involved in the development of white matter lesions. This study aimed to investigate the role of tumor necrosis factor-alpha (TNF-α) in spastic cerebral palsy. MATERIAL AND METHODS Plasma TNF-α was measured by ELISA in 54 children with spastic cerebr...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wu J,Li X

更新日期：2015-12-11 00:00:00

abstract：BACKGROUND:There is evidence that myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by activation of immune, inflammatory, oxidative and nitrosative stress (IO&NS) pathways. The present study was carried out in order to examine whether ME/CFS is accompanied by increased levels of plasma perox...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Maes M,Kubera M,Uytterhoeven M,Vrydags N,Bosmans E

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Hemicellulose containing nutritional supplements demonstrate benefits to the immune system in vitro and in vivo. Here we show that Natramune (PDS-2865) stimulates phagocytosis, nitric oxide production and boosts viability in J774A.1 murine machrophages. We also show that dietary supplementation with Natramun...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Weeks BS,Perez PP

更新日期：2009-02-01 00:00:00