Probiotics for treatment of acute diarrhoea in children: randomised clinical trial of five different preparations.

abstract：OBJECTIVE:To evaluate the effectiveness and costs of a multifaceted flexible educational programme aimed at reducing antibiotic dispensing at the practice level in primary care. DESIGN:Randomised controlled trial with general practices as the unit of randomisation and analysis. Clinicians and researchers were blinded ...

journal_title：BMJ (Clinical research ed.)

authors： Butler CC,Simpson SA,Dunstan F,Rollnick S,Cohen D,Gillespie D,Evans MR,Alam MF,Bekkers MJ,Evans J,Moore L,Howe R,Hayes J,Hare M,Hood K

更新日期：2012-02-02 00:00:00

abstract：OBJECTIVE:To assess treatment related changes in quality of life up to 15 years after diagnosis of localised prostate cancer. DESIGN:Population based, prospective cohort study with follow-up over 15 years. SETTING:New South Wales, Australia. PARTICIPANTS:1642 men with localised prostate cancer, aged less than 70, an...

journal_title：BMJ (Clinical research ed.)

authors： Mazariego CG,Egger S,King MT,Juraskova I,Woo H,Berry M,Armstrong BK,Smith DP

更新日期：2020-10-07 00:00:00

abstract：OBJECTIVE:To develop and refine a complex intervention for diabetes support and education in minority ethnic groups, delivered through bilingual health advocates. DESIGN:Action research framework-a variety of methods used in an emergent and developmental manner, in partnership with clinicians, managers, and service us...

journal_title：BMJ (Clinical research ed.)

authors： Greenhalgh T,Collard A,Begum N

更新日期：2005-03-19 00:00:00

abstract：OBJECTIVE:To assess and compare the accuracy of visual inspection with acetic acid (VIA), visual inspection with Lugol's iodine (VILI), and human papillomavirus (HPV) testing as alternative standalone methods for primary cervical cancer screening in sub-Saharan Africa. DESIGN:Systematic review and meta-analysis of dia...

journal_title：BMJ (Clinical research ed.)

authors： Fokom-Domgue J,Combescure C,Fokom-Defo V,Tebeu PM,Vassilakos P,Kengne AP,Petignat P

更新日期：2015-07-03 00:00:00

abstract：:Two patients with acute major, disabling cerebral infarction with presumed middle cerebral artery occlusion were treated with the clot specific thrombolytic agent tissue plasminogen activator roughly three and a half hours after the onset of symptoms. Both patients had a normal computed tomography (CT) scan before tre...

journal_title：BMJ (Clinical research ed.)

authors： Koudstaal PJ,Stibbe J,Vermeulen M

更新日期：1988-12-17 00:00:00

abstract：:The UN has reported that five multinational pharmaceutical companies would cut down HIV drug prices in the developing world. One of these drug companies is GlaxoWellcome, which has promised to reduce the price of zidovudine and lamivudine to US$2 in the poorest nations, a fifth of its price in the US. Although Peter ...

journal_title：BMJ (Clinical research ed.)

authors： Yamey G

更新日期：2000-05-20 00:00:00

abstract：OBJECTIVES:To investigate the consequences of longstanding obesity on left ventricular mass and structure and to examine the effects of weight loss on these variables. DESIGN:Cross sectional survey and controlled intervention study. SETTING:City of Gothenburg and surrounding areas. Sweden. SUBJECTS:41 obese patients...

journal_title：BMJ (Clinical research ed.)

authors： Karason K,Wallentin I,Larsson B,Sjöström L

更新日期：1997-10-11 00:00:00

abstract：OBJECTIVES:To measure the prevalence of domestic violence among women attending general practice; test the association between experience of domestic violence and demographic factors; evaluate the extent of recording of domestic violence in records held by general practices; and assess acceptability to women of screeni...

journal_title：BMJ (Clinical research ed.)

authors： Richardson J,Coid J,Petruckevitch A,Chung WS,Moorey S,Feder G

更新日期：2002-02-02 00:00:00

abstract：OBJECTIVE:To assess the effects of preventive home visits to elderly people living in the community. DESIGN:Systematic review. SETTING:15 trials retrieved from Medline, Embase, and the Cochrane controlled trial register. MAIN OUTCOME MEASURES:Physical function, psychosocial function, falls, admissions to institution...

journal_title：BMJ (Clinical research ed.)

authors： van Haastregt JC,Diederiks JP,van Rossum E,de Witte LP,Crebolder HF

更新日期：2000-03-18 00:00:00

abstract：OBJECTIVE:To examine doctors' perspectives about their experiences with handheld computers in clinical practice. DESIGN:Qualitative study of eight focus groups consisting of doctors with diverse training and practice patterns. SETTING:Six practice settings across the United States and two additional focus group sessi...

journal_title：BMJ (Clinical research ed.)

authors： McAlearney AS,Schweikhart SB,Medow MA

更新日期：2004-05-15 00:00:00

abstract：OBJECTIVE:To examine variations in teenage pregnancy rates in Trent region and to determine possible associations with local general practice characteristics such as the age and sex of the doctors. DESIGN:Cross sectional survey. SETTING:All 826 general practices in Trent region in existence between 1994 and 1997. SU...

journal_title：BMJ (Clinical research ed.)

authors： Hippisley-Cox J,Allen J,Pringle M,Ebdon D,McPhearson M,Churchill D,Bradley S

更新日期：2000-03-25 00:00:00

abstract：:A sample of 106 senior house officers who had graduated from Nottingham University in 1987 was surveyed about their experience of and need for careers guidance, performance appraisal, and stress counselling. Of the 80 who replied, a quarter had received no careers guidance and a quarter no feedback about their work pe...

journal_title：BMJ (Clinical research ed.)

authors： Garrud P

更新日期：1990-02-17 00:00:00

abstract：OBJECTIVE:To describe the characteristics at birth of children conceived by in vitro fertilisation (IVF) or by gamete intrafallopian transfer (GIFT) and to assess whether they differ from those of children conceived naturally. DESIGN:Survey of children resulting from IVF or GIFT and comparison of their characteristics...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1990-05-12 00:00:00

abstract：OBJECTIVES:To measure, in a service setting, the effect of magnetic resonance imaging on diagnosis, diagnostic certainty, and patient management in the neurosciences; to measure the cost per patient scanned; to estimate the marginal cost of imaging and compare this with its diagnostic impact; to measure changes in pati...

journal_title：BMJ (Clinical research ed.)

authors： Szczepura AK,Fletcher J,Fitz-Patrick JD

更新日期：1991-12-07 00:00:00

abstract：OBJECTIVE:To analyse the relation between treated blood pressure and concomitant risk factor and morbidity from acute myocardial infarction. DESIGN:Prospective longitudinal study. Treated blood pressures and other variables were used to predict acute myocardial infarction. SETTING:Primary health care in Skaraborg, Sw...

journal_title：BMJ (Clinical research ed.)

authors： Lindblad U,Råstam L,Rydén L,Ranstam J,Isacsson SO,Berglund G

更新日期：1994-03-12 00:00:00

abstract：:An association between vasectomy and the development of testicular tumors, and the importance of testicular examinations both before and after a vasectomy is discussed. Patients diagnosed with testicular tumors within the last ten years were examined at Bangour General Hospital in Scotland. From 1977-87, 37 patients...

journal_title：BMJ (Clinical research ed.)

authors： Cale AR,Farouk M,Prescott RJ,Wallace IW

更新日期：1990-02-10 00:00:00

abstract：OBJECTIVES:To see whether telling peer reviewers that their signed reviews of original research papers might be posted on the BMJ's website would affect the quality of their reviews. DESIGN:Randomised controlled trial. SETTING:A large international general medical journal based in the United Kingdom. PARTICIPANTS:54...

journal_title：BMJ (Clinical research ed.)

authors： van Rooyen S,Delamothe T,Evans SJ

更新日期：2010-11-16 00:00:00

abstract：:Hepatitis B virus (HBV) is a global health problem that can lead to cirrhosis and hepatocellular carcinoma (HCC). Although HBV vaccination has reduced the prevalence Of HBV infection, the burden of disease remains high. Treatment with antiviral drugs reduces the risk of liver disease and the development of HCC, and it...

journal_title：BMJ (Clinical research ed.)

authors： Sundaram V,Kowdley K

更新日期：2015-10-21 00:00:00

abstract：OBJECTIVES:To examine the incidence of suicides due to co-proxamol compared with tricyclic antidepressants and paracetamol, and to compare fatality rates for self poisonings with these drugs. DESIGN:Analysis of routinely collected national and local data on suicides and self poisonings. SETTING:Records of suicides in...

journal_title：BMJ (Clinical research ed.)

authors： Hawton K,Simkin S,Deeks J

更新日期：2003-05-10 00:00:00

abstract：OBJECTIVE:To assess the risk of pulmonary embolism, ischaemic stroke, and myocardial infarction associated with combined oral contraceptives according to dose of oestrogen (ethinylestradiol) and progestogen. DESIGN:Observational cohort study. SETTING:Data from the French national health insurance database linked with...

journal_title：BMJ (Clinical research ed.)

authors： Weill A,Dalichampt M,Raguideau F,Ricordeau P,Blotière PO,Rudant J,Alla F,Zureik M

更新日期：2016-05-10 00:00:00

abstract：OBJECTIVE:To determine the clinical and cost effectiveness of booklet based vestibular rehabilitation with and without telephone support for chronic dizziness, compared with routine care. DESIGN:Single blind, parallel group, pragmatic, randomised controlled trial. SETTING:35 general practices across southern England ...

journal_title：BMJ (Clinical research ed.)

authors： Yardley L,Barker F,Muller I,Turner D,Kirby S,Mullee M,Morris A,Little P

更新日期：2012-06-06 00:00:00

abstract：OBJECTIVES:To assess the performance of a panel of common single nucleotide polymorphisms (genotypes) associated with type 2 diabetes in distinguishing incident cases of future type 2 diabetes (discrimination), and to examine the effect of adding genetic information to previously validated non-genetic (phenotype based)...

journal_title：BMJ (Clinical research ed.)

authors： Talmud PJ,Hingorani AD,Cooper JA,Marmot MG,Brunner EJ,Kumari M,Kivimäki M,Humphries SE

更新日期：2010-01-14 00:00:00

abstract：:Objective To characterize the prospective controlled clinical studies for all novel drugs that were initially approved by the Food and Drug Administration on the basis of limited evidence.Design Systematic review.Data sources Drugs@FDA database and PubMed.Study inclusion All prospective controlled clinical studies pub...

journal_title：BMJ (Clinical research ed.)

authors： Pease AM,Krumholz HM,Downing NS,Aminawung JA,Shah ND,Ross JS

更新日期：2017-05-03 00:00:00

abstract：OBJECTIVE:To describe temporal trends in the time interval between first and second attempts at defibrillation and the association between this time interval and outcomes in patients with persistent ventricular tachycardia or ventricular fibrillation (VT/VF) arrest in hospital. DESIGN:Retrospective cohort study SETTI...

journal_title：BMJ (Clinical research ed.)

authors： Bradley SM,Liu W,Chan PS,Nallamothu BK,Grunwald GK,Self A,Sasson C,Varosy PD,Anderson ML,Schneider PM,Ho PM,American Heart Association’s Get With The Guidelines-Resuscitation Investigators.

更新日期：2016-04-06 00:00:00

abstract：OBJECTIVES:To gain insight into people's thoughts on stroke and to inform the development of educational strategies in the community. DESIGN:Focus group discussions: two groups of people who had a stroke and their carers, and two groups of members of the general public. SETTING:New South Wales, Australia. PARTICIPAN...

journal_title：BMJ (Clinical research ed.)

authors： Yoon SS,Byles J

更新日期：2002-05-04 00:00:00

abstract：OBJECTIVE:To establish the extent to which systematic reviews and meta-analyses of individual participant data (IPD) are being used to inform the recommendations included in published clinical guidelines. DESIGN:Descriptive study. SETTING:Database maintained by the Cochrane IPD Meta-analysis Methods Group, supplement...

journal_title：BMJ (Clinical research ed.)

authors： Vale CL,Rydzewska LH,Rovers MM,Emberson JR,Gueyffier F,Stewart LA,Cochrane IPD Meta-analysis Methods Group.

更新日期：2015-03-06 00:00:00

abstract：OBJECTIVE:To compare the effect on prevalence of diarrhoea and mortality of household based treatment of drinking water with flocculant-disinfectant, sodium hypochlorite, and standard practices in areas with turbid water source in Africa. DESIGN:Cluster randomised controlled trial over 20 weeks. SETTING:Family compou...

journal_title：BMJ (Clinical research ed.)

authors： Crump JA,Otieno PO,Slutsker L,Keswick BH,Rosen DH,Hoekstra RM,Vulule JM,Luby SP

更新日期：2005-09-03 00:00:00

abstract：OBJECTIVES:To estimate the prevalence and incidence of divorce among US physicians compared with other healthcare professionals, lawyers, and non-healthcare professionals, and to analyze factors associated with divorce among physicians. DESIGN:Retrospective analysis of nationally representative surveys conducted by th...

journal_title：BMJ (Clinical research ed.)

authors： Ly DP,Seabury SA,Jena AB

更新日期：2015-02-18 00:00:00

abstract：OBJECTIVES:To explore why cancer patients do not want or seek information about their condition beyond that volunteered by their physicians at times during their illness. DESIGN:Qualitative study based on in-depth interviews. SETTING:Outpatient oncology clinics at a London cancer centre. PARTICIPANTS:17 patients wit...

journal_title：BMJ (Clinical research ed.)

authors： Leydon GM,Boulton M,Moynihan C,Jones A,Mossman J,Boudioni M,McPherson K

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To compare the clinical effectiveness of local corticosteroid injection, standard non-steroidal anti-inflammatory drugs, and simple analgesics for the early treatment of lateral epicondylitis in primary care. DESIGN:Multicentre pragmatic randomised controlled trial. SETTING:23 general practices in North Sta...

journal_title：BMJ (Clinical research ed.)

authors： Hay EM,Paterson SM,Lewis M,Hosie G,Croft P

更新日期：1999-10-09 00:00:00