Abstract：
:Resistance training with blood flow restriction is typically performed during single exercises for the lower- or upper-body, which may not replicate real world programming. The present study examined the change in muscle strength and mass in a young healthy population during an 8-week whole body resistance training program, as well as monitoring these adaptations following a 4-week detraining period. Thirty-nine participants (27 males, 12 females) were allocated into four groups: blood flow restriction training (BFR-T); moderate-heavy load training (HL-T), light-load training (LL-T) or a non-exercise control (CON). Testing measurements were taken at Baseline, during mid-point of training (week 4), end of training (week 8) and following four weeks of detraining (week 12) and included anthropometrics, body composition, muscle thickness (MTH) at seven sites, and maximal dynamic strength (1RM) for six resistance exercises. Whole body resistance training with BFR significantly improved lower- and upper-body strength (overall; 11% increase in total tonnage), however, this was similar to LL-T (12%), but both groups were lower in comparison with HL-T (21%) and all groups greater than CON. Some markers of body composition (e.g., lean mass) and MTH significantly increased over the course of the 8-week training period, but these were similar across all groups. Following detraining, whole body strength remained significantly elevated for both BFR-T (6%) and HL-T (14%), but only the HL-T group remained higher than all other groups. Overall, whole body resistance training with blood flow restriction was shown to be an effective training mode to increase muscular strength and mass. However, traditional moderate-heavy load resistance training resulted in greater adaptations in muscle strength and mass as well as higher levels of strength maintenance following detraining.
journal_name
Front Physioljournal_title
Frontiers in physiologyauthors
Brandner CR,Clarkson MJ,Kidgell DJ,Warmington SAdoi
10.3389/fphys.2019.01099subject
Has Abstractpub_date
2019-09-10 00:00:00pages
1099issn
1664-042Xjournal_volume
10pub_type
杂志文章abstract：:The sterile insect technique (SIT) may reduce pest populations by allowing sufficient amount of irradiation-induced sterile males to mate with wild females whilst maintaining mating ability comparable to wild males. Although the SIT methods are well understood, the optimal sterilizing dose and processing development s...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2018.00118
更新日期：2018-02-20 00:00:00
abstract：:There are animal species that have adapted to life at high altitude and hypobaric hypoxia conditions in the Andean highlands. One such species is the llama (Lama glama), which seem to have developed efficient protective mechanisms to avoid maladaptation resulting from chronic hypoxia, such as a resistance to the devel...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2018.00606
更新日期：2018-05-29 00:00:00
abstract：:Hyperbilirubinemia (HB) occurs in 90% of preterm newborns. Moderate HB can induce acute neurological disorders while severe HB has been linked to a higher incidence of apneas of prematurity. The present study aimed to test the hypothesis that even moderate HB disrupts cardiorespiratory control in preterm lambs. Two gr...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2016.00437
更新日期：2016-09-30 00:00:00
abstract：:The free-fall of orbital spaceflight effectively removes the gravitational vector used as a primary spatial orientation reference on Earth. Sustained absence of this reference drives adaptive changes in the internal perception-action models of the central nervous system (CNS), most notably in the processing of the ves...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2018.01680
更新日期：2018-11-27 00:00:00
abstract：:The transient receptor potential vanilloid member 1 (TRPV1) in the central nervous system may contribute to homeostatic plasticity by regulating intracellular Ca2+, which becomes unbalanced in age-related neurodegenerative diseases, including Alzheimer's and Huntington's. Glaucomatous optic neuropathy - the world's le...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2020.00249
更新日期：2020-03-26 00:00:00
abstract：Introduction:Hypothermia has notable effects on platelets, platelet function, fibrinogen, and coagulation factors. Common laboratory techniques cannot identify those effects, because blood samples are usually warmed to 37°C before analysis and do not fully reflect the in vivo situation. Multiple aspects of the pathophy...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2020.00843
更新日期：2020-07-14 00:00:00
abstract：:The mitochondrial oxidative stress theory of aging posits that membrane susceptibility to peroxidation and the organization of the electron transport system (ETS) linked with reactive oxygen species (ROS) generation are two main drivers of lifespan. While a clear correlation has been established from species comparati...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2019.00946
更新日期：2019-07-26 00:00:00
abstract：:To understand dynamic changes in polyamines (PAs) forms and components of polyamine metabolism in zoysiagrass (Zoysia japonica Steud.) response to salt stress with exogenous spermidine (Spd) application, two Chinese zoysia cultivars, z081 and z057, were exposed to sodium chloride stress for 2, 4, 6, and 8 days. The z0...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2017.00208
更新日期：2017-04-06 00:00:00
abstract：:Aim: The current study aimed to examine the effects of resistance exercise with concomitant consumption of high vs. low daily doses of non-steroidal anti-inflammatory drugs (NSAIDs) on mitochondrial oxidative phosphorylation in skeletal muscle. As a secondary aim, we compared the effects of eccentric overload with con...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2017.01074
更新日期：2017-12-19 00:00:00
abstract：:The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders. In brief, the sliding movement of fluorescence-labeled actin filaments on myosin motor proteins is recorded, and the sliding velocity ...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2019.00289
更新日期：2019-03-27 00:00:00
abstract：:Respiratory sensory gating function has been found decreased by induced negative emotion in healthy adults. The increased ratio of the respiratory-related evoked potential (RREP) N1 peak amplitude for the second occlusion (S2) vs. the first occlusion (S1), S2/S1, is indicative of such decreased respiratory sensory gat...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2016.00019
更新日期：2016-02-16 00:00:00
abstract：:Endothelial cells have emerged as key players in SARS-CoV-2 infection and COVID-19 inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation and disease processes like thrombosis, atherosclerosis, and lung injury. In endothelial cells, mitochondria regulate these inflammatory pathways ...
journal_title：Frontiers in physiology
pub_type： 杂志文章,评审
doi：10.3389/fphys.2020.605908
更新日期：2021-01-15 00:00:00
abstract：:Pulmonary edema (PE) is an issue widely noted in acute exposure to hypoxia as seen in high altitude climbers, yet the etiology of this is not defined. Previous studies in rats showed that both hypoxia and strong sympathetic activation may induce PE. As acute exposure to hypoxia is accompanied by sympathetic activation...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2019.00860
更新日期：2019-07-05 00:00:00
abstract：:Background and Objective: It is widely accepted that there is an association between chronic obstructive pulmonary disease (COPD) and periodontitis. However, whether the periodontal status of the COPD patients is worse than that of the non-COPD subjects is seldom assessed. The findings currently available are inconsis...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2018.00033
更新日期：2018-01-25 00:00:00
abstract：:This study aims to present complex network models which analyze professional swimmers of 50-m freestyle Olympic competitions, comparing characteristics and variables that are considered performance determinants. This comparative research includes Olympic medalists' versus non-medalists' behavior. Using data from 40 at...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2019.01134
更新日期：2019-09-03 00:00:00
abstract：:Mitochondrial redox imbalance has been implicated in mechanisms of aging, various degenerative diseases and drug-induced toxicity. Statins are safe and well-tolerated therapeutic drugs that occasionally induce myotoxicity such as myopathy and rhabdomyolysis. Previous studies indicate that myotoxicity caused by statins...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2013.00103
更新日期：2013-05-15 00:00:00
abstract：Objective:Varicose veins are a common problem worldwide and can cause significant impairments in health-related quality of life, but the etiology and pathogenesis remain not well defined. This study aims to elucidate transcriptomic regulations of varicose veins by detecting differentially expressed genes, pathways and ...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2019.00278
更新日期：2019-03-19 00:00:00
abstract：:Before they develop competent endothermy, mammals and birds are sensitive to fluctuating temperature. It follows that early life thermal environment can trigger changes to the ontogeny of thermoregulatory control. At the ecological level, we have incomplete knowledge of how such responses affect temperature tolerance ...
journal_title：Frontiers in physiology
pub_type： 杂志文章,评审
doi：10.3389/fphys.2020.00419
更新日期：2020-05-25 00:00:00
abstract：:Aquaculture is a growing industry that is increasingly providing a sizable proportion of fishery products for human consumption. Dietary energy and temperature fluctuations affect fish health and may even trigger mortality, causing great losses in fish production during winter. To better understand this unproductive w...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2018.00923
更新日期：2018-07-17 00:00:00
abstract：INTRODUCTION:Recently, three independent, intercorrelated biophysical measures have provided the first quantitative measures of a binary form of behavioral laterality called "Hemisity," a term referring to inherent opposite right or left brain-oriented differences in thinking and behavioral styles. Crucially, the right...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2012.00407
更新日期：2012-11-02 00:00:00
abstract：Background/Aims:Enterochromaffin cells (EC cells) constitute the largest population of enteroendocrine cells and release serotonin (5-HT) in response to mechanical and chemical cues of the gastrointestinal tract (GIT). How EC cells respond to altered microbiota such as due to antibiotic treatments remain poorly underst...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2020.605982
更新日期：2020-12-23 00:00:00
abstract：:While it is widely known that marine mammals possess adaptations which allow them to make repetitive and extended dives to great depths without suffering ill effects seen in humans, the response of marine mammal immune cells to diving is unknown. Renewed interest in marine mammal dive physiology has arisen due to repo...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2015.00128
更新日期：2015-05-06 00:00:00
abstract：:Expiratory muscle strength training (EMST) is a rehabilitative program that has been tested for outcomes related to respiratory muscle strength, cough, swallow, and voice function in healthy young adult, elderly individuals, and in patients with progressive neurodegenerative disease. Because EMST has been used in pati...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2012.00048
更新日期：2012-03-13 00:00:00
abstract：:Nicotinamide nucleotide transhydrogenase (TH) is an enzyme complex in animal mitochondria and bacteria that utilizes the electrochemical proton gradient across membranes to drive the production of NADPH. The enzyme plays an important role in maintaining the redox balance of cells with implications in aging and a numbe...
journal_title：Frontiers in physiology
pub_type： 杂志文章,评审
doi：10.3389/fphys.2017.01089
更新日期：2017-12-19 00:00:00
abstract：:Finding an optimum for the cycling performance is not a trivial matter, since the literature shows the presence of many controversial aspects. In order to quantify different levels of performance, several indexes have been defined and used in many studies, reflecting variations in physiological and biomechanical facto...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2013.00116
更新日期：2013-05-21 00:00:00
abstract：:The human brain is constantly active and even small limitations to cerebral blood flow (CBF) may be critical for preserving oxygen and substrate supply, e.g., during exercise and hypoxia. Exhaustive exercise evokes a competition for the supply of oxygenated blood between the brain and the working muscles, and inabilit...
journal_title：Frontiers in physiology
pub_type： 杂志文章,评审
doi：10.3389/fphys.2020.583155
更新日期：2021-01-15 00:00:00
abstract：:Circulating microRNAs have proven to be reliable biomarkers, due to their high stability, both in vivo in the circulation, and ex vivo during sample preparation and storage. Small nucleolar RNAs (snoRNAs) are a different type of small non-coding RNAs that can also be reliably measured in plasma, but have only been stu...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2018.01136
更新日期：2018-08-22 00:00:00
abstract：:Octopuses (Octopus vulgaris) are generally considered to possess extraordinary cognitive abilities including the ability to successfully perform in a serial reversal learning task. During reversal learning, an animal is presented with a discrimination problem and after reaching a learning criterion, the signs of the s...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2017.00054
更新日期：2017-02-07 00:00:00
abstract：:Chronic kidney disease (CKD) caused by renal fibrosis is an important public health concern. It is therefore necessary to understand the molecular pathogenesis of renal fibrosis in order to develop novel therapeutic strategies. KLF4 is the most extensively studied factor among the various members of the Krüppel-like f...
journal_title：Frontiers in physiology
pub_type： 杂志文章,评审
doi：10.3389/fphys.2015.00327
更新日期：2015-11-12 00:00:00
abstract：:Comparison of genomic sequences from diverse vertebrate species has revealed numerous highly conserved regions that do not appear to encode proteins or functional RNAs. Often these "conserved non-coding elements," or CNEs, can direct gene expression to specific tissues in transgenic models, demonstrating they have reg...
journal_title：Frontiers in physiology
pub_type： 杂志文章
doi：10.3389/fphys.2014.00007
更新日期：2014-01-21 00:00:00
