Mitochondrial Traits Previously Associated With Species Maximum Lifespan Do Not Correlate With Longevity Across Populations of the Bivalve Arctica islandica.

abstract：:Adipose tissue, dietary lipids and de novo lipogenesis are sources of hepatic free fatty acids (FFAs) that are stored in lipid droplets (LDs) as triacylglycerols (TAGs). Destiny of TAGs stored in LDs is determined by LD proteomic equipment. When adipose triglyceride lipase (ATGL) localizes at LD surface the lipid mobi...

journal_title：Frontiers in physiology

authors： Grasselli E,Voci A,Demori I,Vecchione G,Compalati AD,Gallo G,Goglia F,De Matteis R,Silvestri E,Vergani L

更新日期：2016-01-12 00:00:00

abstract：:The large amount of energy expended during flapping flight is associated with heat generated through the increased work of the flight muscles. This increased muscle work rate can manifest itself in core body temperature (Tb) increase of 1-2°C in birds during flight. Therefore, episodic body cooling may be mandatory in...

journal_title：Frontiers in physiology

authors： Guillemette M,Polymeropoulos ET,Portugal SJ,Pelletier D

更新日期：2017-07-25 00:00:00

abstract：:We describe a new nonlinear dynamic model of insect phototransduction using a NLN (nonlinear, linear, nonlinear) block structure. The first nonlinear stage provides a single exponential decline in gain and mean following the start of light stimulation. The linear stage uses a two-parameter log-normal convolution model...

journal_title：Frontiers in physiology

authors： French AS,Immonen EV,Frolov RV

更新日期：2016-10-25 00:00:00

abstract：:Insufficient oxygen availability (hypoxia) is a precursor to numerous cardiovascular diseases, including atherosclerosis, pulmonary hypertension, and heart failure. The main site of hypoxic injury in the human body is the mitochondria, where oxygen acts as the final electron acceptor in the process of oxidative phosph...

journal_title：Frontiers in physiology

authors： Liu M,Galli G,Wang Y,Fan Q,Wang Z,Wang X,Xiao W

更新日期：2020-07-15 00:00:00

abstract：:Accurate evaluation of the appearance of QTc sex differences during childhood and adolescence is intricate. Inter-subject differences of individual QT/RR patterns make generic heart rate corrections inaccurate because of fast resting heart rates in children. The study investigated 527 healthy children and adolescents ...

journal_title：Frontiers in physiology

authors： Andršová I,Hnatkova K,Helánová K,Šišáková M,Novotný T,Kala P,Malik M

更新日期：2019-08-02 00:00:00

abstract：:Lactic acid and short chain fatty acids (SCFAs) produced by vaginal microbiota have reported antimicrobial and immune modulatory activities indicating their potential as biomarkers of disease and/or disease susceptibility. In asymptomatic women of reproductive-age the vaginal microbiota is comprised of lactic acid-pro...

journal_title：Frontiers in physiology

authors： Aldunate M,Srbinovski D,Hearps AC,Latham CF,Ramsland PA,Gugasyan R,Cone RA,Tachedjian G

更新日期：2015-06-02 00:00:00

abstract：UNLABELLED:Limitations of current methods: Normalization of resting energy expenditure (REE) for body composition using the 2-compartment model fat mass (FM), and fat-free mass (FFM) has inherent limitations for the interpretation of REE and may lead to erroneous conclusions when comparing people with a wide range of a...

journal_title：Frontiers in physiology

authors： Bosy-Westphal A,Braun W,Schautz B,Müller MJ

更新日期：2013-03-25 00:00:00

abstract：:The central dogma of molecular biology has come under scrutiny in recent years. Here, we reviewed high-throughput mRNA and protein expression data of Escherichia coli, Saccharomyces cerevisiae, and several mammalian cells. At both single cell and population scales, the statistical comparisons between the entire transc...

journal_title：Frontiers in physiology

authors： Piras V,Tomita M,Selvarajoo K

更新日期：2012-11-23 00:00:00

abstract：:It is commonly believed that higher values of heart rate variability (HRV) indices account for better organization of the network of feedback reflexes driving an organism's response to actual bodily needs. In order to evaluate this organization in heart transplant (HTX) recipients, 58 nocturnal Holter signals of 14 HT...

journal_title：Frontiers in physiology

authors： Wdowczyk J,Makowiec D,Gruchała M,Wejer D,Struzik ZR

更新日期：2018-04-09 00:00:00

abstract：:Current cardiac drug safety assessments focus on hERG channel block and QT prolongation for evaluating arrhythmic risks, whereas the optogenetic approach focuses on the action potential (AP) waveform generated by a monolayer of human cardiomyocytes beating synchronously, thus assessing the contribution of several ion ...

journal_title：Frontiers in physiology

authors： Björk S,Ojala EA,Nordström T,Ahola A,Liljeström M,Hyttinen J,Kankuri E,Mervaala E

更新日期：2017-11-02 00:00:00

abstract：:Most sense organs of arthropods are ensconced in small exoskeletal compartments that hinder direct access to plasma membranes. We have developed a method for exposing live sensory and supporting cells in such structures. The technique uses a viscous light cured resin to embed and support the structure, which is then s...

journal_title：Frontiers in physiology

authors： Kay AR,Raccuglia D,Scholte J,Sivan-Loukianova E,Barwacz CA,Armstrong SR,Guymon CA,Nitabach MN,Eberl DF

更新日期：2016-09-12 00:00:00

abstract：:Domestic pig molars provide an interesting system to study the biomineralization process. The large size, thick enamel and complex crown morphology make pig molars relatively similar to human molars. However, compared to human molars, pig molars develop considerably faster. Here we use microCT to image the developing ...

journal_title：Frontiers in physiology

authors： Sova SS,Tjäderhane L,Heikkilä PA,Jernvall J

更新日期：2018-02-09 00:00:00

abstract：:Excitatory and inhibitory junction potentials of circular smooth muscle cells in guinea pig ileum and colon are suppressed 30-90 min after setting up in vitro preparations. We have previously shown this "unresponsive" period is associated with a transient loss of dye coupling between smooth muscle cells, which subsequ...

journal_title：Frontiers in physiology

authors： Carbone SE,Wattchow DA,Spencer NJ,Hibberd TJ,Brookes SJ

更新日期：2014-08-22 00:00:00

abstract：:Many cell division processes have been conserved throughout evolution and are being revealed by studies on model organisms such as bacteria, yeasts, and protozoa. Cellular membrane constriction is one of these processes, observed almost universally during cell division. It happens similarly in all organisms through a ...

journal_title：Frontiers in physiology

authors： Beltrán-Heredia E,Almendro-Vedia VG,Monroy F,Cao FJ

更新日期：2017-05-19 00:00:00

abstract：:Bioenergetic profiling of cancer cells is of great potential because it can bring forward new and effective therapeutic strategies along with early diagnosis. Metabolic Control Analysis (MCA) is a methodology that enables quantification of the flux control exerted by different enzymatic steps in a metabolic network th...

journal_title：Frontiers in physiology

authors： Kaambre T,Chekulayev V,Shevchuk I,Tepp K,Timohhina N,Varikmaa M,Bagur R,Klepinin A,Anmann T,Koit A,Kaldma A,Guzun R,Valvere V,Saks V

更新日期：2013-06-28 00:00:00

abstract：:To date, there has been no study on the long-term effects of resistance exercise on sarcopenia and obesity indices for people with sarcopenia. The present study thus aimed to determine the effect of 18 months of periodized, high-velocity/intensity/effort progressive resistance training (HIT-RT) on body composition and...

journal_title：Frontiers in physiology

authors： Kemmler W,Kohl M,Fröhlich M,Engelke K,von Stengel S,Schoene D

更新日期：2020-08-27 00:00:00

abstract：:High-intensity interval training (HIT) is an effective approach for improving a range of physiological markers associated with physical fitness. A considerable body of work has demonstrated substantial improvements in cardiorespiratory fitness following short-term training programmes, while emerging evidence suggests ...

journal_title：Frontiers in physiology

authors： Hurst C,Scott JPR,Weston KL,Weston M

更新日期：2019-05-22 00:00:00

abstract：:Periodontal ligament contains periodontal ligament stem cells that maintain tissue homeostasis. Targeting hPDLSCs (human periodontal ligament cells) is a promising strategy for repair and regeneration of bone tissue destroyed by periodontal diseases. However, the mechanisms by which PDLSCs differentiate into osteoblas...

journal_title：Frontiers in physiology

authors： Merkel A,Chen Y,George A

更新日期：2019-09-12 00:00:00

abstract：:The Proline, Glutamate, Valine and Lysine-rich (PEVK) region of titin constitutes an entropic spring that provides passive tension to striated muscle. To study the functional and structural repercussions of a small reduction in the size of the PEVK region, we investigated skeletal muscles of a mouse with the constitut...

journal_title：Frontiers in physiology

authors： van der Pijl RJ,Hudson B,Granzier-Nakajima T,Li F,Knottnerus AM,Smith J,Chung CS,Gotthardt M,Granzier HL,Ottenheijm CAC

更新日期：2020-05-29 00:00:00

abstract：:The arterial baroreflexes, located in the carotid sinus and along the arch of the aorta, are essential for the rapid short term autonomic regulation of blood pressure. In the past, they were believed to be inactivated during exercise because blood pressure, heart rate, and sympathetic activity were radically changed f...

journal_title：Frontiers in physiology

authors： Schwartz CE,Stewart JM

更新日期：2012-12-07 00:00:00

abstract：:Coenzyme Q (CoQ) is an essential component of the mitochondrial electron transport chain and an antioxidant in plasma membranes and lipoproteins. It is endogenously produced in all cells by a highly regulated pathway that involves a mitochondrial multiprotein complex. Defects in either the structural and/or regulatory...

journal_title：Frontiers in physiology

authors： Hernández-Camacho JD,Bernier M,López-Lluch G,Navas P

更新日期：2018-02-05 00:00:00

abstract：:Uridine diphosphate (UDP)-glycosyltransferases (UGTs) are major phase II enzymes that conjugate a variety of small lipophilic molecules with UDP sugars and alter them into more water-soluble metabolites. Therefore, glucosidation plays a major role in the inactivation and excretion of a great variety of both endogenous...

journal_title：Frontiers in physiology

authors： Pan Y,Tian F,Wei X,Wu Y,Gao X,Xi J,Shang Q

更新日期：2018-04-03 00:00:00

abstract：:The recognition of invading pathogens and endogenous molecules from damaged tissues by toll-like receptors (TLRs) triggers protective self-defense mechanisms. However, excessive TLR activation disrupts the immune homeostasis by sustained pro-inflammatory cytokines and chemokines production and consequently contributes...

journal_title：Frontiers in physiology

authors： Gao W,Xiong Y,Li Q,Yang H

更新日期：2017-07-19 00:00:00

abstract：:Respiratory sensory gating function has been found decreased by induced negative emotion in healthy adults. The increased ratio of the respiratory-related evoked potential (RREP) N1 peak amplitude for the second occlusion (S2) vs. the first occlusion (S1), S2/S1, is indicative of such decreased respiratory sensory gat...

journal_title：Frontiers in physiology

authors： Chan PY,Cheng CH,Jhu YJ,Chen CL,von Leupoldt A

更新日期：2016-02-16 00:00:00

abstract：:In this paper we develop a novel mathematical model of the insulin-TOR-MAPK signaling network that controls growth. Most data on the properties of the insulin and MAPK signaling networks are static and the responses to experimental interventions, such as knockouts, overexpression, and hormonal input are typically repo...

journal_title：Frontiers in physiology

authors： Nijhout HF,Callier V

更新日期：2013-09-12 00:00:00

abstract：AIM:The signaling pathways involved in the regulation of cardiac GLUT4 translocation/glucose uptake and CD36 translocation/long-chain fatty acid uptake are not fully understood. We compared in heart/muscle-specific PKC-λ knockout mice the roles of atypical PKCs (PKC-ζ and PKC-λ) in regulating cardiac glucose and fatty ...

journal_title：Frontiers in physiology

authors： Habets DD,Luiken JJ,Ouwens M,Coumans WA,Vergouwe M,Maarbjerg SJ,Leitges M,Bonen A,Richter EA,Glatz JF

更新日期：2012-09-11 00:00:00

abstract：:Prescribing the proper resistance training (RT) program is critical to optimize skeletal muscle hypertrophy and strength. Periodization is a strategy that entails planned manipulations of training variables to maximize fitness adaptations while minimizing the risk of overtraining. Multiple meta-analyses have shown per...

journal_title：Frontiers in physiology

authors： Evans JW

更新日期：2019-01-23 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fphys.2019.00621.]. ...

journal_title：Frontiers in physiology

authors： Russo R,Marra R,Andolfo I,De Rosa G,Rosato BE,Manna F,Gambale A,Raia M,Unal S,Barella S,Iolascon A

更新日期：2020-08-11 00:00:00

abstract：:Background: An amount of cognition decline is normal with aging; however, intrinsic and extrinsic risk factors may exacerbate it, affecting social and occupational tasks. Masticatory dysfunction (MD), as a general term, refers to an impairment in the masticatory function triggered by a structural factor, such as tooth...

journal_title：Frontiers in physiology

authors： Alvarenga MOP,Ferreira RO,Magno MB,Fagundes NCF,Maia LC,Lima RR

更新日期：2019-07-03 00:00:00

abstract：:Purpose: To provide insights into the energy requirements as well as the physiological adaptations of an experienced 50-year-old ultra-marathon male athlete during the world's most challenging mountain ultra-marathon (MUM). Methods: The international race supporting the study was the Tor des Geants®, characterized by ...

journal_title：Frontiers in physiology

authors： Savoldelli A,Fornasiero A,Trabucchi P,Limonta E,La Torre A,Degache F,Pellegrini B,Millet GP,Vernillo G,Schena F

更新日期：2017-12-05 00:00:00