Triglyceride Mobilization from Lipid Droplets Sustains the Anti-Steatotic Action of Iodothyronines in Cultured Rat Hepatocytes.

abstract：:A new concept of non-rapid eye movement (NREM) and rapid eye movement (REM) sleep is proposed, that of multi-component integrative states that define stable and unstable sleep, respectively, NREMS, NREMUS REMS, and REMUS. Three complementary data sets are used: obstructive sleep apnea (20), healthy subjects (11), and ...

journal_title：Frontiers in physiology

authors： Wood C,Bianchi MT,Yun CH,Shin C,Thomas RJ

更新日期：2020-12-03 00:00:00

abstract：:Prone position can reduce mortality in acute respiratory distress syndrome (ARDS), but several studies found variable effects on oxygenation and lung mechanics. It is unclear whether different positive end-expiratory pressure (PEEP) titration techniques modify the effect of prone position. We tested, in an animal mode...

journal_title：Frontiers in physiology

authors： Scaramuzzo G,Ball L,Pino F,Ricci L,Larsson A,Guérin C,Pelosi P,Perchiazzi G

更新日期：2020-03-12 00:00:00

abstract：:Glucagon counterregulation (GCR) protects against hypoglycemia, but is impaired in type 1 diabetes (T1DM). A model-based analysis of in vivo animal data predicts that the GCR defects are linked to basal hyperglucagonemia. To test this hypothesis we studied the relationship between basal glucagon (BasG) and the GCR res...

journal_title：Frontiers in physiology

authors： Farhy LS,Chan A,Breton MD,Anderson SM,Kovatchev BP,McCall AL

更新日期：2012-02-28 00:00:00

abstract：:This work investigates the effect of arterial bifurcation angulation on atherosclerosis development through in-silico simulations of coupled cell dynamics. The computational model presented here combines cellular pathways, fluid dynamics, and physiologically-realistic vessel geometries as observed in the human vascula...

journal_title：Frontiers in physiology

authors： Dowding S,Zakkaroff C,Moore S,David T

更新日期：2018-10-31 00:00:00

abstract：:Periodontal ligament contains periodontal ligament stem cells that maintain tissue homeostasis. Targeting hPDLSCs (human periodontal ligament cells) is a promising strategy for repair and regeneration of bone tissue destroyed by periodontal diseases. However, the mechanisms by which PDLSCs differentiate into osteoblas...

journal_title：Frontiers in physiology

authors： Merkel A,Chen Y,George A

更新日期：2019-09-12 00:00:00

abstract：:Prior peripheral hypoxia induced via remote ischemic preconditioning (IPC) can improve physical performance in male athletes through improved O2 delivery and utilization. Since females may have an innate protective mechanism against ischemia-reperfusion injury, and since muscle metabolism during contraction differs be...

journal_title：Frontiers in physiology

authors： Paradis-Deschênes P,Joanisse DR,Billaut F

更新日期：2017-01-05 00:00:00

abstract：:Gut microbiota has been reported to contribute to reduced diet-induced obesity upon cold exposure. Furthermore, gut microbiome fermentation determines the efficacy of exercise for diabetes prevention and enhances exercise performance. However, there have been no systematic examinations of changes in gut microbiome com...

journal_title：Frontiers in physiology

authors： Meng Y,Chen L,Lin W,Wang H,Xu G,Weng X

更新日期：2020-05-04 00:00:00

abstract：:This review details the manner in which the central nervous system regulates metabolic homeostasis in normal weight and obese rodents and humans. It includes a review of the homeostatic contributions of neurons located in the hypothalamus, the midbrain and limbic structures, the pons and the medullary area postrema, n...

journal_title：Frontiers in physiology

authors： Smith JK

更新日期：2018-05-17 00:00:00

abstract：:Chronic pressure overload can result in ventricular hypertrophy and eventually diastolic dysfunction. In normal myocardium, the time from peak tension to 50% relaxation of isolated cardiac myocardium is not directly determined by the time for calcium decline. This study aims to determine whether the time for calcium d...

journal_title：Frontiers in physiology

authors： Monasky MM,Torres CAA,Janssen PML

更新日期：2017-12-04 00:00:00

abstract：:Eccentric loading is an effective stimulus for muscle hypertrophy and strength gains, however, the effect of lengthening velocity is under debate. The purpose of the current study was to investigate the influence of muscle lengthening velocity during eccentric training on muscle hypertrophy and strength gains at a giv...

journal_title：Frontiers in physiology

authors： Marzilger R,Bohm S,Mersmann F,Arampatzis A

更新日期：2019-07-31 00:00:00

abstract：:Circulating mitochondrial DNA (mtDNA) is receiving increasing attention as a danger-associated molecular pattern in conditions such as autoimmunity or trauma. In the context of decompression sickness (DCS), the course of which is sometimes erratic, we hypothesize that mtDNA plays a not insignificant role particularly ...

journal_title：Frontiers in physiology

authors： Blatteau JE,Gaillard S,De Maistre S,Richard S,Louges P,Gempp E,Druelles A,Lehot H,Morin J,Castagna O,Abraini JH,Risso JJ,Vallée N

更新日期：2018-11-29 00:00:00

abstract：:Basketball is a team sport, where fundamental skills - fundamentals - are key determinants for success. Jump-shot (JS) is a basketball fundamental used frequently during game. It is interesting to spread light on the relationship between effort intensity and JS ability. Study aim was to investigate different heart rat...

journal_title：Frontiers in physiology

authors： Padulo J,Nikolaidis PT,Cular D,Dello Iacono A,Vando S,Galasso M,Lo Storto D,Ardigò LP

更新日期：2018-08-03 00:00:00

abstract：:Infants born premature are at increased risk for development of bronchopulmonary dysplasia (BPD), pulmonary hypertension (PH), and ultimately right ventricular (RV) dysfunction, which together carry a high risk of neonatal mortality. However, the role alveolar simplification and abnormal pulmonary microvascular develo...

journal_title：Frontiers in physiology

authors： Patel JR,Barton GP,Braun RK,Goss KN,Haraldsdottir K,Hopp A,Diffee G,Hacker TA,Moss RL,Eldridge MW

更新日期：2017-10-25 00:00:00

abstract：:Perfluorooctanoic acid (PFOA) has been detected in various water bodies and caused harm to aquatic organisms. The aim of this study was to investigate the cytotoxicity and mechanism associated with autophagy and oxidative stress after exposure to PFOA (0, 1, 10, 100 μg/L) for 12 h on lymphocytes, which was isolated fr...

journal_title：Frontiers in physiology

authors： Tang J,Lu X,Chen F,Ye X,Zhou D,Yuan J,He J,Chen B,Shan X,Jiang J,Liu W,Zhang H

更新日期：2018-12-05 00:00:00

abstract：:While isolation of the pulmonary veins is firmly established as effective treatment for the majority of paroxysmal atrial fibrillation (AF) patients, there is recognition that patients with persistent AF have substrate for perpetuation of arrhythmia existing outside of the pulmonary veins. Various computational approa...

journal_title：Frontiers in physiology

authors： Stiles MK,Sanders P,Lau DH

更新日期：2018-09-18 00:00:00

abstract：:Renal fibrosis is characterized by progressive accumulation of extracellular matrix (ECM) proteins, resulting in loss of organ function and eventually requiring renal replacement therapy. Unfortunately, no efficacious treatment options are available to halt renal fibrosis and translational models to test pharmacologic...

journal_title：Frontiers in physiology

authors： Stribos EGD,Seelen MA,van Goor H,Olinga P,Mutsaers HAM

更新日期：2017-12-12 00:00:00

abstract：:Previous studies assessing effect of ischemia on ventricular repolarization are mostly directed toward patients with coronary artery disease (CAD); however, similar reports on cardiac syndrome X (CSX) are scarce. Whether microvascular dysfunction of CSX and ischemia induced by CAD produce comparable effect on ventricu...

journal_title：Frontiers in physiology

authors： Lutfi MF

更新日期：2016-09-21 00:00:00

abstract：:Molar hypomineralisation (MH) is becoming globally recognised as a significant public health problem linked to childhood tooth decay. However, with causation and pathogenesis unclear after 100 years of investigation, better pathological understanding is needed if MH is to become preventable. Our studies have implicate...

journal_title：Frontiers in physiology

authors： Perez VA,Mangum JE,Hubbard MJ

更新日期：2020-09-30 00:00:00

abstract：:Domestic pig molars provide an interesting system to study the biomineralization process. The large size, thick enamel and complex crown morphology make pig molars relatively similar to human molars. However, compared to human molars, pig molars develop considerably faster. Here we use microCT to image the developing ...

journal_title：Frontiers in physiology

authors： Sova SS,Tjäderhane L,Heikkilä PA,Jernvall J

更新日期：2018-02-09 00:00:00

abstract：:Defining variations in skeletal muscle passive mechanical properties at different size scales ranging from single muscle fibers to whole muscles is required in order to understand passive muscle function. It is also of interest from a muscle structural point-of-view to identify the source(s) of passive tension that fu...

journal_title：Frontiers in physiology

authors： Ward SR,Winters TM,O'Connor SM,Lieber RL

更新日期：2020-03-20 00:00:00

abstract：:Sudden cardiac death caused by ventricular arrhythmias is among the leading causes of mortality, with approximately half of all deaths attributed to heart disease worldwide. Periodic repolarization dynamics (PRD) is a novel marker of repolarization instability and strong predictor of death in patients post-myocardial ...

journal_title：Frontiers in physiology

authors： Ang R,Marina N

更新日期：2020-03-18 00:00:00

abstract：:Accurate evaluation of the appearance of QTc sex differences during childhood and adolescence is intricate. Inter-subject differences of individual QT/RR patterns make generic heart rate corrections inaccurate because of fast resting heart rates in children. The study investigated 527 healthy children and adolescents ...

journal_title：Frontiers in physiology

authors： Andršová I,Hnatkova K,Helánová K,Šišáková M,Novotný T,Kala P,Malik M

更新日期：2019-08-02 00:00:00

abstract：:Voltage-gated potassium (Kv) channels shape the action potentials of excitable cells and regulate membrane potential and ion homeostasis in excitable and non-excitable cells. With 40 known members in the human genome and a variety of homomeric and heteromeric pore-forming α subunit interactions, post-translational mod...

journal_title：Frontiers in physiology

authors： Kanda VA,Abbott GW

更新日期：2012-06-28 00:00:00

abstract：:We investigate analytically the production of entropy during a breathing cycle in healthy and diseased lungs. First, we calculate entropy production in healthy lungs by applying the laws of thermodynamics to the well-known transpulmonary pressure-volume (P-V) curves of the lung under the assumption that lung tissue be...

journal_title：Frontiers in physiology

authors： Oliveira CL,Araújo AD,Bates JH,Andrade JS Jr,Suki B

更新日期：2016-03-01 00:00:00

abstract：:Loss of skeletal muscle myofibrillar protein with disease and/or inactivity can severely deteriorate muscle strength and function. Strategies to counteract wasting of muscle myofibrillar protein are therefore desirable and invite for considerations on the potential superiority of specific modes of resistance exercise ...

journal_title：Frontiers in physiology

authors： Rindom E,Vissing K

更新日期：2016-11-17 00:00:00

abstract：:Octopamine (OA) is a prominent neuromodulator of invertebrate nervous systems, influencing multiple physiological processes. Among its many roles in insects are the initiation and maintenance of various rhythmic behaviors. Here, the neuromodulatory effects of OA on the components of the locust stomatogastric nervous s...

journal_title：Frontiers in physiology

authors： Rand D,Knebel D,Ayali A

更新日期：2012-07-20 00:00:00

abstract：:Left ventricular hypertrophy (LVH) is a major contributor to the development of heart failure (HF). Alterations in cyclic adenosine monophosphate (cAMP)-dependent signaling pathways participate in cardiomyocyte hypertrophy and mitochondrial dysfunction occurring in LVH and HF. cAMP signals are received and integrated ...

journal_title：Frontiers in physiology

authors： Schiattarella GG,Boccella N,Paolillo R,Cattaneo F,Trimarco V,Franzone A,D'Apice S,Giugliano G,Rinaldi L,Borzacchiello D,Gentile A,Lombardi A,Feliciello A,Esposito G,Perrino C

更新日期：2018-05-28 00:00:00

abstract：:Lepidopteran species detect CO2 via a specialized organ located on the peripheral segment of the labial palps, the labial palp pit organ (LPO). Based on tracing of LPO sensory neurons targeting one distinct antennal-lobe glomerulus, Kent and her colleagues described the projections originating from the LPO in the sphi...

journal_title：Frontiers in physiology

authors： Kc P,Chu X,Kvello P,Zhao XC,Wang GR,Berg BG

更新日期：2020-03-17 00:00:00

abstract：:Respiratory sensory gating function has been found decreased by induced negative emotion in healthy adults. The increased ratio of the respiratory-related evoked potential (RREP) N1 peak amplitude for the second occlusion (S2) vs. the first occlusion (S1), S2/S1, is indicative of such decreased respiratory sensory gat...

journal_title：Frontiers in physiology

authors： Chan PY,Cheng CH,Jhu YJ,Chen CL,von Leupoldt A

更新日期：2016-02-16 00:00:00

abstract：:The Subolesin/Akirin constitutes a good model for the study of functional evolution because these proteins have been conserved throughout the metazoan and play a role in the regulation of different biological processes. Here, we investigated the evolutionary history of Subolesin/Akirin with recent results on their str...

journal_title：Frontiers in physiology

authors： Artigas-Jerónimo S,Villar M,Cabezas-Cruz A,Valdés JJ,Estrada-Peña A,Alberdi P,de la Fuente J

更新日期：2018-11-13 00:00:00