Reduction in the Level of Plasma Mitochondrial DNA in Human Diving, Followed by an Increase in the Event of an Accident.

abstract：:Being the central metabolic organ of vertebrates, the liver possesses the largest repertoire of metabolic enzymes among all tissues and organs. Almost all metabolic pathways are resident in the parenchymal cell, hepatocyte, but the pathway capacities may largely differ depending on the localization of hepatocytes with...

journal_title：Frontiers in physiology

authors： Berndt N,Holzhütter HG

更新日期：2018-12-12 00:00:00

abstract：:The management of cancer patients is frequently complicated by the occurrence of cachexia. This is a complex syndrome that markedly impacts on quality of life as well as on tolerance and response to anticancer treatments. Loss of body weight, wasting of both adipose tissue and skeletal muscle and reduced survival rate...

journal_title：Frontiers in physiology

authors： Penna F,Ballarò R,Beltrà M,De Lucia S,García Castillo L,Costelli P

更新日期：2019-02-18 00:00:00

abstract：:Background: In chronic hypoxia (CH) and short-term chronic intermittent hypoxia (CIH) exposure, glycemia and insulin levels decrease and insulin sensitivity increases, which can be explained by changes in glucose transport at skeletal muscles involving GLUT1, GLUT4, Akt, and AMPK, as well as GLUT4 translocation to cel...

journal_title：Frontiers in physiology

authors： Siques P,Brito J,Flores K,Ordenes S,Arriaza K,Pena E,León-Velarde F,López de Pablo ÁL,Gonzalez MC,Arribas S

更新日期：2018-06-28 00:00:00

abstract：:Our understanding of the etiological mechanisms leading up to epilepsy has undergone radical changes over time due to more insights into the complexity of the disease. The traditional hypothesis emphasized network hyperexcitability and an imbalance of inhibition and excitation, eventually leading to seizures. In this ...

journal_title：Frontiers in physiology

authors： Baruah J,Vasudevan A,Köhling R

更新日期：2020-01-22 00:00:00

abstract：:In the last three decades, all efforts in bone tissue engineering were driven by the dogma that the ideal pore size in bone substitutes lies between 0.3 and 0.5 mm in diameter. Newly developed additive manufacturing methodologies for ceramics facilitate the total control over pore size, pore distribution, bottleneck s...

journal_title：Frontiers in physiology

authors： Ghayor C,Weber FE

更新日期：2018-07-19 00:00:00

abstract：AIM:The signaling pathways involved in the regulation of cardiac GLUT4 translocation/glucose uptake and CD36 translocation/long-chain fatty acid uptake are not fully understood. We compared in heart/muscle-specific PKC-λ knockout mice the roles of atypical PKCs (PKC-ζ and PKC-λ) in regulating cardiac glucose and fatty ...

journal_title：Frontiers in physiology

authors： Habets DD,Luiken JJ,Ouwens M,Coumans WA,Vergouwe M,Maarbjerg SJ,Leitges M,Bonen A,Richter EA,Glatz JF

更新日期：2012-09-11 00:00:00

abstract：:Pulmonary edema (PE) is an issue widely noted in acute exposure to hypoxia as seen in high altitude climbers, yet the etiology of this is not defined. Previous studies in rats showed that both hypoxia and strong sympathetic activation may induce PE. As acute exposure to hypoxia is accompanied by sympathetic activation...

journal_title：Frontiers in physiology

authors： Bölter C,Gabriel P,Appelt P,Salameh A,Schierle K,Rassler B

更新日期：2019-07-05 00:00:00

abstract：:The spinal cord demonstrates several forms of plasticity that resemble brain-dependent learning and memory. Among the most studied form of spinal plasticity is spinal memory for noxious (nociceptive) stimulation. Numerous papers have described central pain as a spinally-stored memory that enhances future responses to ...

journal_title：Frontiers in physiology

authors： Ferguson AR,Huie JR,Crown ED,Grau JW

更新日期：2012-10-04 00:00:00

abstract：:Cardiac arrest is a prevalent condition with a poor prognosis, attributable in part to persistent myocardial dysfunction following resuscitation. The molecular basis of this dysfunction remains unclear. We induced cardiac arrest in a porcine model of acute sudden death and assessed the impact of ischemia and reperfusi...

journal_title：Frontiers in physiology

authors： Woodward M,Previs MJ,Mader TJ,Debold EP

更新日期：2015-07-16 00:00:00

abstract：:The extensive literature dealing with the Golgi system emphasizes its role in protein secretion and modification, usually without specifying from which evolutionary ancient cell physiological necessity such secretion originated. Neither does it specify which functional requirements the secreted proteins must meet. Fro...

journal_title：Frontiers in physiology

authors： De Loof A,Schoofs L

更新日期：2020-10-15 00:00:00

abstract：:Hemoglobin (Hb) is a highly conserved molecule present in all life forms and functionally tied to the complexity of aerobic organisms on earth in utilizing oxygen from the atmosphere and delivering to cells and tissues. This primary function sustains the energy requirements of cells and maintains cellular homeostasis....

journal_title：Frontiers in physiology

authors： Quaye IK

更新日期：2015-04-20 00:00:00

abstract：:Glutathione (GSH) deficits have been observed in several mental or degenerative illness, and so has the metabolic syndrome. The impact of a decreased glucose metabolism on the GSH system is well-known, but the effect of decreased GSH levels on the energy metabolism is unclear. The aim of the present study was to inves...

journal_title：Frontiers in physiology

authors： Lavoie S,Steullet P,Kulak A,Preitner F,Do KQ,Magistretti PJ

更新日期：2016-04-21 00:00:00

abstract：:For many model organisms traditionally in use for cardiac electrophysiological studies, characterization of ion channel genes is lacking. We focused here on two genes encoding the inward rectifier current, KCNJ2 and KCNJ12, in the dog heart. A combination of RT-PCR, 5'-RACE, and 3'-RACE demonstrated the status of KCNJ...

journal_title：Frontiers in physiology

authors： Houtman MJ,Takanari H,Kok BG,van Eck M,Montagne DR,Vos MA,de Boer TP,van der Heyden MA

更新日期：2012-01-30 00:00:00

abstract：:The knowledge of possible acute and long-term health effects of aerosols inhaled from electronic cigarettes (ECs) is still limited partially due to incomplete awareness of physical phenomena related to EC-aerosol dynamics. This short review discusses the basic processes of aerosol transformation (dynamics) upon inhala...

journal_title：Frontiers in physiology

authors： Sosnowski TR,Odziomek M

更新日期：2018-07-09 00:00:00

abstract：:Ginseng, the root of Panax ginseng C.A. Meyer, is one of the oldest traditional medicines and is thought to be a tonic. It has been claimed that ginseng may improve vitality and health. Recent studies have advanced ginseng pharmacology and shown that ginseng has various pharmacological effects in the nervous system. G...

journal_title：Frontiers in physiology

authors： Nah SY

更新日期：2014-03-19 00:00:00

abstract：:Regular physical exercise provides many health benefits, protecting against the development of chronic diseases, and improving quality of life. Some of the mechanisms by which exercise provides these effects are the promotion of an anti-inflammatory state, reinforcement of the neuromuscular function, and activation of...

journal_title：Frontiers in physiology

authors： Cerdá B,Pérez M,Pérez-Santiago JD,Tornero-Aguilera JF,González-Soltero R,Larrosa M

更新日期：2016-02-18 00:00:00

abstract：:To determine the level of hypoxia from which muscle activation (MA) is reduced during incremental exercise to exhaustion (IE), and the role played by PIO2 in this process, ten volunteers (21 ± 2 years) performed four IE in severe acute hypoxia (SAH) (PIO2 = 73 mmHg). Upon exhaustion, subjects were asked to continue ex...

journal_title：Frontiers in physiology

authors： Torres-Peralta R,Losa-Reyna J,Morales-Alamo D,González-Izal M,Pérez-Suárez I,Ponce-González JG,Izquierdo M,Calbet JA

更新日期：2016-08-17 00:00:00

abstract：:This review details the manner in which the central nervous system regulates metabolic homeostasis in normal weight and obese rodents and humans. It includes a review of the homeostatic contributions of neurons located in the hypothalamus, the midbrain and limbic structures, the pons and the medullary area postrema, n...

journal_title：Frontiers in physiology

authors： Smith JK

更新日期：2018-05-17 00:00:00

abstract：:Octopamine (OA) is a prominent neuromodulator of invertebrate nervous systems, influencing multiple physiological processes. Among its many roles in insects are the initiation and maintenance of various rhythmic behaviors. Here, the neuromodulatory effects of OA on the components of the locust stomatogastric nervous s...

journal_title：Frontiers in physiology

authors： Rand D,Knebel D,Ayali A

更新日期：2012-07-20 00:00:00

abstract：:Background: Nrg4 expression has been linked to brown adipose tissue activity and browning of white adipocytes in mice. Here, we aimed to investigate whether these observations could be translated to humans by investigating NRG4 mRNA and markers of brown/beige adipocytes in human visceral (VAT) and subcutaneous adipose...

journal_title：Frontiers in physiology

authors： Comas F,Martínez C,Sabater M,Ortega F,Latorre J,Díaz-Sáez F,Aragonés J,Camps M,Gumà A,Ricart W,Fernández-Real JM,Moreno-Navarrete JM

更新日期：2019-01-31 00:00:00

abstract：:The multifunctional CD36 scavenger receptor facilitates fatty acid (FA) uptake and oxidation and it has been involved in the pathophysiology related to dysfunctional FA metabolism. The common variant in the CD36 gene, rs1761667 (A/G), whose allele A is characterized by a reduced protein expression, has been associated...

journal_title：Frontiers in physiology

authors： Melis M,Carta G,Pintus S,Pintus P,Piras CA,Murru E,Manca C,Di Marzo V,Banni S,Tomassini Barbarossa I

更新日期：2017-12-06 00:00:00

abstract：:Mild normobaric hypoxia (NH) and modest exercise have multiple beneficial effects on health, but the changes in physiological function induced by NH and/or exercise remain unclear. The purpose of this investigation was to examine the specific effects of NH and/or exercise on cardiac function and myocardial structure a...

journal_title：Frontiers in physiology

authors： Li QF,Wang H,Zheng L,Yang F,Li HZ,Li JX,Cheng D,Lu K,Liu Y

更新日期：2020-01-21 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is the most common mendelian heart disease, with a prevalence of 1/500. HCM is a primary cause of sudden death, due to an heightened risk of ventricular tachyarrhythmias that often occur in young asymptomatic patients. HCM can slowly progress toward heart failure, either with preserve...

journal_title：Frontiers in physiology

authors： Coppini R,Ferrantini C,Mugelli A,Poggesi C,Cerbai E

更新日期：2018-10-16 00:00:00

abstract：:The aim of this study was to examine the effects of Lactobacillus brevis on the microbial community and serum metabolome in colitis induced by dextran sulfate sodium (DSS). ICR mice were randomly distributed into three treatment groups: (i) L. brevis treatment alone (control), (ii) DSS administration alone, and (iii) ...

journal_title：Frontiers in physiology

authors： Ding S,Ma Y,Liu G,Yan W,Jiang H,Fang J

更新日期：2019-09-18 00:00:00

abstract：:Regulation of energy homeostasis is fundamental for life. In animal species and humans, the Central Nervous System (CNS) plays a critical role in such regulation by integrating peripheral signals and modulating behavior and the activity of peripheral organs. A precise interplay between CNS and peripheral signals is ne...

journal_title：Frontiers in physiology

authors： Kim JD,Leyva S,Diano S

更新日期：2014-12-09 00:00:00

abstract：:In an emerging bioelectronics era, there is a clinical need for physiological devices incorporating biofeedback that permits natural and demand-dependent control in real time. Here, we describe a novel device termed a central pattern generator (CPG) that uses cutting edge analog circuitry producing temporally controll...

journal_title：Frontiers in physiology

authors： O'Callaghan EL,Chauhan AS,Zhao L,Lataro RM,Salgado HC,Nogaret A,Paton JF

更新日期：2016-02-04 00:00:00

abstract：:The aim of this study is to detect the effects of C60 fullerenes, which possess pronounced antioxidant properties, in comparison with the actions of the known exogenous antioxidants N-acetylcysteine (NAC) and β-Alanine in terms of exercise tolerance and contractile property changes of the m. triceps surae (TS) during ...

journal_title：Frontiers in physiology

authors： Vereshchaka IV,Bulgakova NV,Maznychenko AV,Gonchar OO,Prylutskyy YI,Ritter U,Moska W,Tomiak T,Nozdrenko DM,Mishchenko IV,Kostyukov AI

更新日期：2018-05-15 00:00:00

abstract：:Arrhythmogenic cardiomyopathy (AC) has originally been described as a disorder characterized by fibrofatty replacement of the myocardium, primarily of the right ventricle (RV), and ventricular tachyarrhythmias, sudden death, and at a late stage progressive heart failure. Arrhythmogenic right ventricular dysplasia or c...

journal_title：Frontiers in physiology

authors： Hauer RN,Cox MG,Groeneweg JA

更新日期：2012-09-17 00:00:00

abstract：:Fractal phenomena can be found in numerous scientific areas including neuroscience. Fractals are structures, in which the whole has the same shape as its parts. A specific structure known as pink noise (also called fractal or 1/f noise) is one key fractal manifestation, exhibits both stability and adaptability, and ca...

journal_title：Frontiers in physiology

authors： Akhrif A,Romanos M,Domschke K,Schmitt-Boehrer A,Neufang S

更新日期：2018-10-04 00:00:00

abstract：:Single-channel kinetics has proven a powerful tool to reveal information about the gating mechanisms that control the opening and closing of ion channels. This introductory review focuses on the gating of large conductance Ca(2+)- and voltage-activated K(+) (BK or Slo1) channels at the single-channel level. It starts ...

journal_title：Frontiers in physiology

authors： Geng Y,Magleby KL

更新日期：2015-01-21 00:00:00