The arterial baroreflex resets with orthostasis.

abstract：:The mitochondrial oxidative stress theory of aging posits that membrane susceptibility to peroxidation and the organization of the electron transport system (ETS) linked with reactive oxygen species (ROS) generation are two main drivers of lifespan. While a clear correlation has been established from species comparati...

journal_title：Frontiers in physiology

authors： Rodríguez E,Dégletagne C,Hagen TM,Abele D,Blier PU

更新日期：2019-07-26 00:00:00

abstract：:The knowledge of possible acute and long-term health effects of aerosols inhaled from electronic cigarettes (ECs) is still limited partially due to incomplete awareness of physical phenomena related to EC-aerosol dynamics. This short review discusses the basic processes of aerosol transformation (dynamics) upon inhala...

journal_title：Frontiers in physiology

authors： Sosnowski TR,Odziomek M

更新日期：2018-07-09 00:00:00

abstract：:Alzheimer's disease (AD) is a major neurodegenerative disease and is one of the most common cause of dementia in older adults. Among several factors, neuroinflammation is known to play a critical role in the pathogenesis of chronic neurodegenerative diseases. In particular, studies of brains affected by AD show a clea...

journal_title：Frontiers in physiology

authors： Ravichandran S,Michelucci A,Del Sol A

更新日期：2018-03-02 00:00:00

abstract：:Recent progress in high-throughput data acquisition has shifted the focus from data generation to processing and understanding of how to integrate collected information. Context specific reconstruction based on generic genome scale models like ReconX or HMR has the potential to become a diagnostic and treatment tool t...

journal_title：Frontiers in physiology

authors： Pacheco MP,Pfau T,Sauter T

更新日期：2016-01-22 00:00:00

abstract：:Coenzyme Q (CoQ) is an essential component of the mitochondrial electron transport chain and an antioxidant in plasma membranes and lipoproteins. It is endogenously produced in all cells by a highly regulated pathway that involves a mitochondrial multiprotein complex. Defects in either the structural and/or regulatory...

journal_title：Frontiers in physiology

authors： Hernández-Camacho JD,Bernier M,López-Lluch G,Navas P

更新日期：2018-02-05 00:00:00

abstract：:3-iodothyronamine (T1AM) is an endogenous amine, that has been detected in many rodent tissues, and in human blood. It has been hypothesized to derive from thyroid hormone metabolism, but this hypothesis still requires validation. T1AM is not a ligand for nuclear thyroid hormone receptors, but stimulates with nanomola...

journal_title：Frontiers in physiology

authors： Zucchi R,Accorroni A,Chiellini G

更新日期：2014-10-16 00:00:00

abstract：:Aim: The current study aimed to examine the effects of resistance exercise with concomitant consumption of high vs. low daily doses of non-steroidal anti-inflammatory drugs (NSAIDs) on mitochondrial oxidative phosphorylation in skeletal muscle. As a secondary aim, we compared the effects of eccentric overload with con...

journal_title：Frontiers in physiology

authors： Cardinale DA,Lilja M,Mandić M,Gustafsson T,Larsen FJ,Lundberg TR

更新日期：2017-12-19 00:00:00

abstract：:Systems biology approaches provide means to study the interplay between biological processes leading to the mechanistic understanding of the properties of complex biological systems. Here, we developed a vector format rule-based Boolean logic model of the yeast S. cerevisiae cAMP-PKA, Snf1, and the Snf3-Rgt2 pathway t...

journal_title：Frontiers in physiology

authors： Welkenhuysen N,Schnitzer B,Österberg L,Cvijovic M

更新日期：2019-01-21 00:00:00

abstract：:Cardiac autonomic function can be quantified through mean heart rate (HR) or heart rate variability (HRV). Numerous studies have supported the utility of different HRV parameters as indicators of cardiorespiratory fitness (CRF). However, HR has recently shown to be a stronger predictor of CRF than HRV in healthy young...

journal_title：Frontiers in physiology

authors： Plaza-Florido A,Migueles JH,Mora-Gonzalez J,Molina-Garcia P,Rodriguez-Ayllon M,Cadenas-Sanchez C,Esteban-Cornejo I,Solis-Urra P,de Teresa C,Gutiérrez Á,Michels N,Sacha J,Ortega FB

更新日期：2019-05-07 00:00:00

abstract：:Background: Acute mountain sickness (AMS) is a common disabling condition in individuals experiencing high altitudes, which may progress to life-threatening high altitude cerebral edema. Today, no established biomarkers are available for prediction the susceptibility of AMS. MicroRNAs emerge as promising sensitive and...

journal_title：Frontiers in physiology

authors： Liu B,Huang H,Wu G,Xu G,Sun BD,Zhang EL,Chen J,Gao YQ

更新日期：2017-02-08 00:00:00

abstract：:Inflammation-induced impaired function of vascular endothelium may cause leakage of plasma proteins that can lead to edema. Proteins may leave the vascular lumen through two main paracellular and transcellular pathways. As the first involves endothelial cell (EC) junction proteins and the second caveolae formation, th...

journal_title：Frontiers in physiology

authors： Muradashvili N,Tyagi R,Lominadze D

更新日期：2012-05-31 00:00:00

abstract：:Developing new methods to treat heart diseases is always a focus for basic research and clinical applications. Existing drugs have strong side-effects and also require lifetime administration for patients. Recent attempts of using nanoparticles (NPs) in treating atherosclerosis in animals and some heart diseases such ...

journal_title：Frontiers in physiology

authors： Zhang J,Ma A,Shang L

更新日期：2018-05-29 00:00:00

abstract：:Respiratory sensory gating function has been found decreased by induced negative emotion in healthy adults. The increased ratio of the respiratory-related evoked potential (RREP) N1 peak amplitude for the second occlusion (S2) vs. the first occlusion (S1), S2/S1, is indicative of such decreased respiratory sensory gat...

journal_title：Frontiers in physiology

authors： Chan PY,Cheng CH,Jhu YJ,Chen CL,von Leupoldt A

更新日期：2016-02-16 00:00:00

abstract：:Bioenergetic profiling of cancer cells is of great potential because it can bring forward new and effective therapeutic strategies along with early diagnosis. Metabolic Control Analysis (MCA) is a methodology that enables quantification of the flux control exerted by different enzymatic steps in a metabolic network th...

journal_title：Frontiers in physiology

authors： Kaambre T,Chekulayev V,Shevchuk I,Tepp K,Timohhina N,Varikmaa M,Bagur R,Klepinin A,Anmann T,Koit A,Kaldma A,Guzun R,Valvere V,Saks V

更新日期：2013-06-28 00:00:00

abstract：:The Paramisgurnus dabryanus was exposed to air to assess the changes in plasma, liver and muscle free amino acid (FAA) contents. The FAA concentrations in plasma, liver and muscle of P. dabryanus were significantly affected by aerial exposure (P < 0.05). After 12 h of aerial exposure, the plasma glutamate contents inc...

journal_title：Frontiers in physiology

authors： Zhang YL,Wang GY,Zhang ZH,Xie YY,Jin H,Dong ZR

更新日期：2019-01-29 00:00:00

abstract：:Adaptation of arm reaching in a novel force field involves co-contraction of upper limb muscles, but it is not known how the co-ordination of multiple muscle activation is orchestrated. We have used intermuscular coherence (IMC) to test whether a coherent intermuscular coupling between muscle pairs is responsible for ...

journal_title：Frontiers in physiology

authors： Pizzamiglio S,De Lillo M,Naeem U,Abdalla H,Turner DL

更新日期：2017-01-09 00:00:00

abstract：:Defects in mitochondrial ribosomal proteins (MRPs) cause various diseases in humans. Because of the essential role of MRPs in synthesizing the essential subunits of oxidative phosphorylation (OXPHOS) complexes, identifying all of the protein components involved in the mitochondrial translational machinery is critical....

journal_title：Frontiers in physiology

authors： Koc EC,Cimen H,Kumcuoglu B,Abu N,Akpinar G,Haque ME,Spremulli LL,Koc H

更新日期：2013-07-30 00:00:00

abstract：:Background: Tissue availability of polyunsaturated fatty acids (PUFA) depends on several factors, including dietary intake, physical exercise, genetic variation, and metabolic turnover. However, there is limited evidence whether running training activity per se may influence indices associated with PUFA metabolism suc...

journal_title：Frontiers in physiology

authors： Davinelli S,Corbi G,Righetti S,Casiraghi E,Chiappero F,Martegani S,Pina R,De Vivo I,Simopoulos AP,Scapagnini G

更新日期：2019-04-26 00:00:00

abstract：:Catheter ablation therapy for persistent atrial fibrillation (AF) typically includes pulmonary vein isolation (PVI) and may include additional ablation lesions that target patient-specific anatomical, electrical, or structural features. Clinical centers employ different ablation strategies, which use imaging data toge...

journal_title：Frontiers in physiology

authors： Roney CH,Beach ML,Mehta AM,Sim I,Corrado C,Bendikas R,Solis-Lemus JA,Razeghi O,Whitaker J,O'Neill L,Plank G,Vigmond E,Williams SE,O'Neill MD,Niederer SA

更新日期：2020-09-16 00:00:00

abstract：:The detection of error information is an essential prerequisite of a feedback-based movement. This study investigated the differential behavior and neurophysiological mechanisms of a cyclic force-tracking task using error-reducing and error-enhancing feedback. The discharge patterns of a relatively large number of mot...

journal_title：Frontiers in physiology

authors： Chen YC,Lin YT,Chang GC,Hwang IS

更新日期：2017-03-13 00:00:00

abstract：:The extracellular tooth enamel matrix is a unique, protein-rich environment that provides the structural basis for the growth of long and parallel oriented enamel crystals. Here we have conducted a series of in vivo and in vitro studies to characterize the changes in matrix shape and organization that take place durin...

journal_title：Frontiers in physiology

authors： Pandya M,Lin T,Li L,Allen MJ,Jin T,Luan X,Diekwisch TGH

更新日期：2017-10-17 00:00:00

abstract：:Background: Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) is highly effective in alleviating motor symptoms of Parkinson's disease (PD) which are not optimally controlled by dopamine replacement therapy. Clinical studies and reports suggest that STN-DBS may result in increased impulsivity and de novo impulse co...

journal_title：Frontiers in physiology

authors： Mandali A,Chakravarthy VS,Rajan R,Sarma S,Kishore A

更新日期：2016-11-29 00:00:00

abstract：:Tubular aggregates (TAs) in skeletal muscle fibers are unusual accumulation of sarcoplasmic reticulum (SR) tubes that are found in different disorders including TA myopathy (TAM). TAM is a muscular disease characterized by muscle pain, cramping, and weakness that has been recently linked to mutations in STIM1 and ORAI...

journal_title：Frontiers in physiology

authors： Boncompagni S,Pecorai C,Michelucci A,Pietrangelo L,Protasi F

更新日期：2021-01-05 00:00:00

abstract：:The multifunctional CD36 scavenger receptor facilitates fatty acid (FA) uptake and oxidation and it has been involved in the pathophysiology related to dysfunctional FA metabolism. The common variant in the CD36 gene, rs1761667 (A/G), whose allele A is characterized by a reduced protein expression, has been associated...

journal_title：Frontiers in physiology

authors： Melis M,Carta G,Pintus S,Pintus P,Piras CA,Murru E,Manca C,Di Marzo V,Banni S,Tomassini Barbarossa I

更新日期：2017-12-06 00:00:00

abstract：:We previously demonstrated that ureteral obstruction is associated with a urinary concentrating defect and reduced expression of renal aquaporins (AQPs), in which the renin-angiotensin system (RAS) may play an important role. The aims of the present study were to examine whether the renin inhibitor aliskiren could pre...

journal_title：Frontiers in physiology

authors： Hu S,Xie H,Luo R,Feng P,Liu Q,Han M,Kong Y,Zou X,Wang W,Li C

更新日期：2019-09-13 00:00:00

abstract：:Moonlighting proteins are a subset of multifunctional proteins characterized by their multiple, independent, and unrelated biological functions. We recently set up a large-scale identification of moonlighting proteins using a protein-protein interaction (PPI) network approach. We established that 3% of the current hum...

journal_title：Frontiers in physiology

authors： Zanzoni A,Chapple CE,Brun C

更新日期：2015-06-23 00:00:00

abstract：:The age at which women experience their first pregnancy has increased throughout the decades. Pregnancy has an important influence on maternal short- and long-term cardiovascular outcomes. Pregnancy at an advanced maternal age increases maternal risk of gestational diabetes, preeclampsia, placenta previa and caesarian...

journal_title：Frontiers in physiology

authors： Morton JS,Care AS,Kirschenman R,Cooke CL,Davidge ST

更新日期：2017-06-30 00:00:00

abstract：:In order to investigate protective roles of dietary selenium yeast (SY) and tea polyphenols (TPs) on growth of juvenile Wuchang bream (Megalobrama amblycephala) and its resistance under ammonia stress, juvenile Wuchang bream were randomly assigned into four groups: a control group fed basal diets and three treatment g...

journal_title：Frontiers in physiology

authors： Guo H,Lin W,Hou J,Wang L,Zhang D,Wu X,Li L,Li D

更新日期：2018-10-02 00:00:00

abstract：:Voltage-gated potassium (Kv) channels shape the action potentials of excitable cells and regulate membrane potential and ion homeostasis in excitable and non-excitable cells. With 40 known members in the human genome and a variety of homomeric and heteromeric pore-forming α subunit interactions, post-translational mod...

journal_title：Frontiers in physiology

authors： Kanda VA,Abbott GW

更新日期：2012-06-28 00:00:00

abstract：:Whether mouse models of chronic asthma can be used to investigate the relationship between airway inflammation/remodeling and airway hyper-responsiveness (AHR) is a vexed question. It raises issues about the extent to which such models replicate key features of the human disease. Here, we review some of the characteri...

journal_title：Frontiers in physiology

authors： Kumar RK,Foster PS

更新日期：2012-07-31 00:00:00