Metabolic control analysis of respiration in human cancer tissue.

abstract：:The mDurance® system is an innovative digital tool that combines wearable surface electromyography (sEMG), mobile computing and cloud analysis to streamline and automatize the assessment of muscle activity. The tool is particularly devised to support clinicians and sport professionals in their daily routines, as an as...

journal_title：Frontiers in physiology

authors： Molina-Molina A,Ruiz-Malagón EJ,Carrillo-Pérez F,Roche-Seruendo LE,Damas M,Banos O,García-Pinillos F

更新日期：2020-11-27 00:00:00

abstract：:Airway hyperresponsiveness (AHR), a characteristic of asthma that involves an excessive reduction in airway caliber, is a complex mechanism reflecting multiple processes that manifest over a large range of length and time scales. At one extreme, molecular interactions determine the force generated by airway smooth mus...

journal_title：Frontiers in physiology

authors： Lauzon AM,Bates JH,Donovan G,Tawhai M,Sneyd J,Sanderson MJ

更新日期：2012-06-11 00:00:00

abstract：:Neuromuscular training in young athletes improves performance and decreases the risk of injuries during sports activities. These effects are primarily ascribed to the enhancement of muscle strength and power but also balance, speed and agility. However, most studies have failed to demonstrate significant improvement i...

journal_title：Frontiers in physiology

authors： Zemková E,Hamar D

更新日期：2018-04-11 00:00:00

abstract：:There are animal species that have adapted to life at high altitude and hypobaric hypoxia conditions in the Andean highlands. One such species is the llama (Lama glama), which seem to have developed efficient protective mechanisms to avoid maladaptation resulting from chronic hypoxia, such as a resistance to the devel...

journal_title：Frontiers in physiology

authors： López V,Moraga FA,Llanos AJ,Ebensperger G,Taborda MI,Uribe E

更新日期：2018-05-29 00:00:00

abstract：:Many studies have investigated the physiological response to microgravity in both astronauts and animals. However, while space agencies have sought to deploy more women on their missions; animal models rarely include females studies or comparisons between males and females. Therefore, we exposed adult female rats to 2...

journal_title：Frontiers in physiology

authors： Semple C,Riveros D,Nagy JA,Rutkove SB,Mortreux M

更新日期：2020-04-03 00:00:00

abstract：:Background: Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) is highly effective in alleviating motor symptoms of Parkinson's disease (PD) which are not optimally controlled by dopamine replacement therapy. Clinical studies and reports suggest that STN-DBS may result in increased impulsivity and de novo impulse co...

journal_title：Frontiers in physiology

authors： Mandali A,Chakravarthy VS,Rajan R,Sarma S,Kishore A

更新日期：2016-11-29 00:00:00

abstract：Background:Spontaneously Hypertensive Rats (SHR) have chronically elevated blood pressures at 30 weeks of age (systolic: 191.0 ± 1.0, diastolic: 128.8 ± 0.9). However, despite this chronic malignant hypertension, SHR kidneys remain relatively free of pathology due to having an augmented myogenic constriction (MC). We h...

journal_title：Frontiers in physiology

authors： Nademi S,Lu C,Dickhout JG

更新日期：2020-07-22 00:00:00

abstract：:Although motor output of the postural function clearly influences postural performance in young and older subjects, no relationship has been formally established between them. However, the relationship between lower-extremity muscle strength/power and postural performance is often pointed out, especially in older subj...

journal_title：Frontiers in physiology

authors： Paillard T

更新日期：2017-08-15 00:00:00

abstract：:[This corrects the article on p. 165 in vol. 7, PMID: 27242539.]. ...

journal_title：Frontiers in physiology

authors： Nielsen AL,Chen S,Fleischer SJ

更新日期：2017-08-11 00:00:00

abstract：:While isolation of the pulmonary veins is firmly established as effective treatment for the majority of paroxysmal atrial fibrillation (AF) patients, there is recognition that patients with persistent AF have substrate for perpetuation of arrhythmia existing outside of the pulmonary veins. Various computational approa...

journal_title：Frontiers in physiology

authors： Stiles MK,Sanders P,Lau DH

更新日期：2018-09-18 00:00:00

abstract：:Ameloblasts are ectoderm-derived cells that produce an extracellular enamel matrix that mineralizes to form enamel. The development and use of immortalized cell lines, with a stable phenotype, is an important contribution to biological studies as it allows for the investigation of molecular activities without the cont...

journal_title：Frontiers in physiology

authors： Sarkar J,Simanian EJ,Tuggy SY,Bartlett JD,Snead ML,Sugiyama T,Paine ML

更新日期：2014-07-25 00:00:00

abstract：:Fatigue is one of the most debilitating symptoms of multiple sclerosis (MS), and the underlying mechanisms are poorly understood. When exposed to a physical or cognitive challenge, individuals with MS tend to exhibit greater declines in task performance (performance fatigability) and increased levels of self-reported ...

journal_title：Frontiers in physiology

authors： Gould JR,Reineberg AE,Cleland BT,Knoblauch KE,Clinton GK,Banich MT,Corboy JR,Enoka RM

更新日期：2018-10-17 00:00:00

abstract：:In our digitized society, advanced information and communication technology and highly interactive work environments impose high demands on cognitive capacity. Optimal workload conditions are important for assuring employee's health and safety of other persons. This is particularly relevant in safety-critical occupati...

journal_title：Frontiers in physiology

authors： Radüntz T,Fürstenau N,Mühlhausen T,Meffert B

更新日期：2020-04-21 00:00:00

abstract：:Coronary microembolization (CME) is an important clinical problem, and it is related to poor outcome. The specific molecular mechanisms of CME are not fully understood. In the present study, we established a mice model of CME. Isobaric tags for relative and absolute quantitation (iTRAQ) and liquid chromatography coupl...

journal_title：Frontiers in physiology

authors： Chen A,Chen Z,Xia Y,Lu D,Jia J,Hu K,Sun A,Zou Y,Qian J,Ge J

更新日期：2018-09-19 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is a genetic disorder caused by mutations in different genes mainly encoding myofilament proteins and therefore called a "disease of the sarcomere." Despite the discovery of sarcomere protein mutations linked to HCM almost 30 years ago, the cellular mechanisms responsible for the deve...

journal_title：Frontiers in physiology

authors： Chowdhury SAK,Warren CM,Simon JN,Ryba DM,Batra A,Varga P,Kranias EG,Tardiff JC,Solaro RJ,Wolska BM

更新日期：2020-03-10 00:00:00

abstract：:Exhaled breath carbon monoxide (eCO) is a candidate biomarker for non-invasive assessment of oxidative stress and respiratory diseases. Standard end-tidal CO analysis, however, cannot distinguish, whether eCO reflects endogenous CO production, lung diffusion properties or exogenous sources, and is unable to resolve a ...

journal_title：Frontiers in physiology

authors： Ghorbani R,Blomberg A,Schmidt FM

更新日期：2018-07-30 00:00:00

abstract：:Mitochondrial redox imbalance has been implicated in mechanisms of aging, various degenerative diseases and drug-induced toxicity. Statins are safe and well-tolerated therapeutic drugs that occasionally induce myotoxicity such as myopathy and rhabdomyolysis. Previous studies indicate that myotoxicity caused by statins...

journal_title：Frontiers in physiology

authors： La Guardia PG,Alberici LC,Ravagnani FG,Catharino RR,Vercesi AE

更新日期：2013-05-15 00:00:00

abstract：:The liver was among the first organs in which connexin proteins have been identified. Hepatocytes harbor connexin32 and connexin26, while non-parenchymal liver cells typically express connexin43. Connexins give rise to hemichannels, which dock with counterparts on adjacent cells to form gap junctions. Both hemichannel...

journal_title：Frontiers in physiology

authors： Maes M,Decrock E,Cogliati B,Oliveira AG,Marques PE,Dagli ML,Menezes GB,Mennecier G,Leybaert L,Vanhaecke T,Rogiers V,Vinken M

更新日期：2014-01-10 00:00:00

abstract：:Melanization reflects not only body color variation but also environmental plasticity. It is a strategy that helps insects adapt to environmental change. Different color morphs may have distinct life history traits, e.g., development time, growth rate, and body weight. The green slender planthopper Saccharosydne proce...

journal_title：Frontiers in physiology

authors： Yin H,Shi Q,Shakeel M,Kuang J,Li J

更新日期：2016-09-12 00:00:00

abstract：:Circulating microRNAs have proven to be reliable biomarkers, due to their high stability, both in vivo in the circulation, and ex vivo during sample preparation and storage. Small nucleolar RNAs (snoRNAs) are a different type of small non-coding RNAs that can also be reliably measured in plasma, but have only been stu...

journal_title：Frontiers in physiology

authors： Håkansson KEJ,Sollie O,Simons KH,Quax PHA,Jensen J,Nossent AY

更新日期：2018-08-22 00:00:00

abstract：:Elderly healthy individuals have a reduced exercise tolerance and a decreased left ventricle inotropic reserve related to increased vascular afterload, arterial-ventricular load mismatching, physical deconditioning and impaired autonomic regulation (the so called "β-adrenergic desensitization"). Adrenergic responsiven...

journal_title：Frontiers in physiology

authors： Ferrara N,Komici K,Corbi G,Pagano G,Furgi G,Rengo C,Femminella GD,Leosco D,Bonaduce D

更新日期：2014-01-09 00:00:00

abstract：:Hypoxia has important effects on biological activity in crustaceans, and modulation of energy metabolism is a crucial aspect of crustaceans' ability to respond to hypoxia. The adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) enzyme is very important in cellular energy homeostasis; however, little infor...

journal_title：Frontiers in physiology

authors： Sun S,Gu Z,Fu H,Zhu J,Ge X,Wu X

更新日期：2018-06-14 00:00:00

abstract：:Background: The severity of wildland fires is increasing due to continually hotter and drier summers. Firefighters are required to make life altering decisions on the fireground, which requires analytical thinking, problem solving, and situational awareness. This study aimed to determine the effects of very hot (45°C;...

journal_title：Frontiers in physiology

authors： Williams-Bell FM,Aisbett B,Murphy BA,Larsen B

更新日期：2017-10-24 00:00:00

abstract：:Acute kidney injury (AKI), which involves the loss of kidney function caused by damage to renal tubular cells, is an important public health concern. We previously showed that sirtuin (SIRT)3 protects the kidneys against mitochondrial damage by inhibiting the nucleotide-binding domain (NOD)-like receptor protein 3 (NL...

journal_title：Frontiers in physiology

authors： Zhao W,Zhang L,Chen R,Lu H,Sui M,Zhu Y,Zeng L

更新日期：2018-11-14 00:00:00

abstract：:Ischemia/reperfusion (I/R) injury induces irreversible oxidative stress damage to the cardiac myocytes. Many studies have revealed that propofol alleviates the important organelle-mediated injury from oxidative stress in vitro. However, it remains unclear whether propofol prevents I/R-induced DNA damage in cardiomyocy...

journal_title：Frontiers in physiology

authors： Zhou D,Zhuang J,Wang Y,Zhao D,Zhao L,Zhu S,Pu J,Yin M,Zhang H,Wang Z,Hong J

更新日期：2019-03-15 00:00:00

abstract：:Electronic cigarettes (ECs) are a modern nicotine delivery system that rapidly grew in widespread use, particularly in younger populations. Given the long history of the comorbidity of alcohol and nicotine use, the rising prevalence of ECs raises the question as to their role in the consumption of alcohol. Of the nume...

journal_title：Frontiers in physiology

authors： Wetzel TJ,Wyatt TA

更新日期：2020-11-02 00:00:00

abstract：:Background: The results from animal and human research indicate that acute intermittent hypoxia can enhance brain-derived neurotrophic factor (BDNF) plasma levels and gene expression. As BDNF is known to promote the differentiation of new neurons and the formation of synapses, it has been proposed to mediate adult neu...

journal_title：Frontiers in physiology

authors： Becke A,Müller P,Dordevic M,Lessmann V,Brigadski T,Müller NG

更新日期：2018-10-01 00:00:00

abstract：:Fibrosis is intimately linked to wound healing and is one of the largest causes of wound-related morbidity. While scar formation is the normal and inevitable outcome of adult mammalian cutaneous wound healing, scarring varies widely between different anatomical sites. The spectrum of craniofacial wound healing spans a...

journal_title：Frontiers in physiology

authors： desJardins-Park HE,Mascharak S,Chinta MS,Wan DC,Longaker MT

更新日期：2019-03-29 00:00:00

abstract：:The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders. In brief, the sliding movement of fluorescence-labeled actin filaments on myosin motor proteins is recorded, and the sliding velocity ...

journal_title：Frontiers in physiology

authors： Bopp N,Scheid LM,Fink RHA,Rohr K

更新日期：2019-03-27 00:00:00

abstract：:Arboviruses are emerging/reemerging infectious agents worldwide. The factors within this scenario include vector and host population fluctuations, climatic changes, anthropogenic activities that disturb ecosystems, an increase in international flights, human mobility, and genetic mutations that allow spill-over phenom...

journal_title：Frontiers in physiology

authors： Diaz LA,Flores FS,Quaglia A,Contigiani MS

更新日期：2013-01-11 00:00:00