Proteomics Analysis of Myocardial Tissues in a Mouse Model of Coronary Microembolization.

abstract：:Despite vast improvement in perinatal care during the 30 years, the incidence rate of neonatal encephalopathy remains unchanged without any further Progress towards preventive strategies for the clinical impasse. Antenatal brain injury including fetal intracranial hemorrhage caused by ischemia/reperfusion is known as ...

journal_title：Frontiers in physiology

authors： Funamoto K,Ito T,Funamoto K,Velayo CL,Kimura Y

更新日期：2017-05-24 00:00:00

abstract：:Preeclampsia, a pregnancy-specific disorder, presents a major health problem during gestation, but is also associated with increased risk for cardiovascular complications in later life. We aimed to investigate whether chronic stress experience and preeclampsia may have additive adverse effects on the cardiac ability t...

journal_title：Frontiers in physiology

authors： Lackner HK,Moertl MG,Schmid-Zalaudek K,Lucovnik M,Weiss EM,Kolovetsiou-Kreiner V,Papousek I

更新日期：2018-09-03 00:00:00

abstract：:Preterm birth complications are the leading cause of child death worldwide and a top global health priority. Among the survivors, the risk of life-long disabilities is high, including cerebral palsy and impairment of movement, cognition, and behavior. Understanding the molecular mechanisms of preterm brain injuries is...

journal_title：Frontiers in physiology

authors： Pregnolato S,Chakkarapani E,Isles AR,Luyt K

更新日期：2019-04-24 00:00:00

abstract：:The management of cancer patients is frequently complicated by the occurrence of cachexia. This is a complex syndrome that markedly impacts on quality of life as well as on tolerance and response to anticancer treatments. Loss of body weight, wasting of both adipose tissue and skeletal muscle and reduced survival rate...

journal_title：Frontiers in physiology

authors： Penna F,Ballarò R,Beltrà M,De Lucia S,García Castillo L,Costelli P

更新日期：2019-02-18 00:00:00

abstract：:Immunity and cellular metabolism are tightly interconnected but it is not clear whether different pathogens elicit specific metabolic responses. To address this issue, we studied differential metabolic regulation in peripheral blood mononuclear cells (PBMCs) of healthy volunteers challenged by Candida albicans, Borrel...

journal_title：Frontiers in physiology

authors： Zhang X,Mardinoglu A,Joosten LAB,Kuivenhoven JA,Li Y,Netea MG,Groen AK

更新日期：2018-02-27 00:00:00

abstract：:Hallucinations - compelling perceptions of stimuli that aren't really there - occur in many psychiatric and neurological disorders, and are triggered by certain drugs of abuse. Despite their clinical importance, the neuronal mechanisms giving rise to hallucinations are poorly understood, in large part due to the absen...

journal_title：Frontiers in physiology

authors： Lee AH,Brandon CL,Wang J,Frost WN

更新日期：2018-06-25 00:00:00

abstract：:Introduction: Baroreflex sensitivity (BRS) is essential to ensure rapid adjustment to variations in blood pressure (BP). Little is known concerning the adaptive responses of BRS during acclimatization to high altitude at rest and during exercise. Methods: Twenty-one healthy sea-level residents were tested near sea lev...

journal_title：Frontiers in physiology

authors： Bourdillon N,Yazdani S,Subudhi AW,Lovering AT,Roach RC,Vesin JM,Kayser B

更新日期：2018-06-21 00:00:00

abstract：:Actual theaters of operations require fast actions from special operations units with a high level of readiness and survival. Mission accomplishment depends on their psychological and physiological performance. The aim of the present study was to analyze: (1) the physical parameters related with success in a special o...

journal_title：Frontiers in physiology

authors： Hormeño-Holgado AJ,Nikolaidis PT,Clemente-Suárez VJ

更新日期：2019-07-10 00:00:00

abstract：:Background: Understanding the microscopic dynamics of the beating heart has been challenging due to the technical nature of imaging with micrometer resolution while the heart moves. The development of multiphoton microscopy has made in vivo, cell-resolved measurements of calcium dynamics and vascular function possible...

journal_title：Frontiers in physiology

authors： Jones JS,Small DM,Nishimura N

更新日期：2018-07-31 00:00:00

abstract：:This study aimed to evaluate the effect of the stretch-shortening cycle (SSC) on different portions of the force-velocity (F-V) relationship in older adults with and without chronic obstructive pulmonary disease (COPD), and to assess its association with physical function. The participants were 26 older adults with CO...

journal_title：Frontiers in physiology

authors： Navarro-Cruz R,Alcazar J,Rodriguez-Lopez C,Losa-Reyna J,Alfaro-Acha A,Ara I,García-García FJ,Alegre LM

更新日期：2019-03-26 00:00:00

abstract：:[This corrects the article on p. 354 in vol. 10, PMID: 30984032.]. ...

journal_title：Frontiers in physiology

authors： Clos P,Laroche D,Stapley PJ,Lepers R

更新日期：2020-08-12 00:00:00

abstract：:Neuromuscular training in young athletes improves performance and decreases the risk of injuries during sports activities. These effects are primarily ascribed to the enhancement of muscle strength and power but also balance, speed and agility. However, most studies have failed to demonstrate significant improvement i...

journal_title：Frontiers in physiology

authors： Zemková E,Hamar D

更新日期：2018-04-11 00:00:00

abstract：:Connexin hemichannels, which are plasma membrane hexameric channels (connexons) composed of connexin protein protomers, have been implicated in a host of physiological processes and pathological conditions. A number of single point pathological mutations impart a "leaky" character to the affected hemichannels, i.e., m...

journal_title：Frontiers in physiology

authors： Ziraldo G,Buratto D,Kuang Y,Xu L,Carrer A,Nardin C,Chiani F,Salvatore AM,Paludetti G,Lerner RA,Yang G,Zonta F,Mammano F

更新日期：2019-06-11 00:00:00

abstract：:The bicuspid aortic valve, a kind of heart disease that comes from parents, has been paid attention around the world. Although most bicuspid aortic valve (BAV) patients will suffer from some complications including aortic stenosis, aortic regurgitation, endocarditis, and heart dysfunction in the late stage of the dise...

journal_title：Frontiers in physiology

authors： Liu T,Xie M,Lv Q,Li Y,Fang L,Zhang L,Deng W,Wang J

更新日期：2019-01-30 00:00:00

abstract：:Activation of autonomic neural pathways by chronic hypertensive stimuli plays a significant role in pathogenesis of hypertension. Here, we proposed that even a single acute hypertensive stimulus will activate neural and immune pathways that may be important in initiation of memory imprinting seen in chronic hypertensi...

journal_title：Frontiers in physiology

authors： Zubcevic J,Santisteban MM,Perez PD,Arocha R,Hiller H,Malphurs WL,Colon-Perez LM,Sharma RK,de Kloet A,Krause EG,Febo M,Raizada MK

更新日期：2017-08-31 00:00:00

abstract：:Hyperglycemia is the main feature of diabetes and may increase the risk of vascular calcification (VC), which is an independent predictor for cardiovascular and cerebrovascular diseases (CCD). Selenium (Se) may decrease the risk of CCD, and previous studies confirmed that Se-containing protein from Se-enriched Spiruli...

journal_title：Frontiers in physiology

authors： Lin C,Zhang LJ,Li B,Zhang F,Shen QR,Kong GQ,Wang XF,Cui SH,Dai R,Cao WQ,Zhang P

更新日期：2020-07-09 00:00:00

abstract：:Recently, we reported that Dahl salt-sensitive leptin receptor mutant (SSLepRmutant) rats exhibit dyslipidemia and renal lipid accumulation independent of hyperglycemia that progresses to chronic kidney disease (CKD). Therefore, in the current study, we examined the effects of gemfibrozil, a lipid-lowering drug (200 m...

journal_title：Frontiers in physiology

authors： Shields CA,Poudel B,McPherson KC,Brown AK,Ekperikpe US,Browning E,Sutton L,Cornelius DC,Williams JM

更新日期：2020-09-18 00:00:00

abstract：:The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to the challenging field of virtual design and testing of technologies in a patient-specific environment. Given the recent advances in medical imaging, computational power and mathematical algorithms, patient-specific cardiac models ...

journal_title：Frontiers in physiology

authors： Zhong L,Zhang JM,Su B,Tan RS,Allen JC,Kassab GS

更新日期：2018-06-26 00:00:00

abstract：:Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture. The effect of hypoxia on cilia length is still controversial in cultured cells, and no corre...

journal_title：Frontiers in physiology

authors： Shamloo K,Chen J,Sardar J,Sherpa RT,Pala R,Atkinson KF,Pearce WJ,Zhang L,Nauli SM

更新日期：2017-09-20 00:00:00

abstract：:Molecular chaperones are stress proteins that allow the correct folding or unfolding as well as the assembly or disassembly of macromolecular cellular components. Changes in expression and post-translational modifications of chaperones have been linked to a number of age- and stress-related diseases including cancer, ...

journal_title：Frontiers in physiology

authors： Penna C,Sorge M,Femminò S,Pagliaro P,Brancaccio M

更新日期：2018-03-16 00:00:00

abstract：:Perfluorooctanoic acid (PFOA) has been detected in various water bodies and caused harm to aquatic organisms. The aim of this study was to investigate the cytotoxicity and mechanism associated with autophagy and oxidative stress after exposure to PFOA (0, 1, 10, 100 μg/L) for 12 h on lymphocytes, which was isolated fr...

journal_title：Frontiers in physiology

authors： Tang J,Lu X,Chen F,Ye X,Zhou D,Yuan J,He J,Chen B,Shan X,Jiang J,Liu W,Zhang H

更新日期：2018-12-05 00:00:00

abstract：:Studies have revealed a robust and independent correlation between chronic kidney disease (CKD) and cardiovascular (CV) events, including death, heart failure, and myocardial infarction. Recent clinical trials extend this range of adverse CV events, including malignant ventricular arrhythmias and sudden cardiac death ...

journal_title：Frontiers in physiology

authors： Kiuchi MG,Ho JK,Nolde JM,Gavidia LML,Carnagarin R,Matthews VB,Schlaich MP

更新日期：2020-01-14 00:00:00

abstract：:Objective: This study aims to investigate the effect of astragaloside IV on adipose lipolysis and hepatic gluconeogenesis. Methods: High-fat diet (HFD) feeding induced adipose dysfunction with enhanced endogenous glucose production in mice. The effects of Astragaloside IV on lipolysis and hepatic glucose production we...

journal_title：Frontiers in physiology

authors： Du Q,Zhang S,Li A,Mohammad IS,Liu B,Li Y

更新日期：2018-01-23 00:00:00

abstract：:Laodelphax striatellus is naturally infected with the Wolbachia strain wStri, which induces strong cytoplasmic incompatibility of its host. MicroRNAs (miRNAs) are a class of endogenous non-coding small RNAs that play a critical role in the regulation of gene expression at post-transcriptional level in various biologic...

journal_title：Frontiers in physiology

authors： Liu L,Zhang KJ,Rong X,Li YY,Liu H

更新日期：2019-07-24 00:00:00

abstract：:This study aims to present complex network models which analyze professional swimmers of 50-m freestyle Olympic competitions, comparing characteristics and variables that are considered performance determinants. This comparative research includes Olympic medalists' versus non-medalists' behavior. Using data from 40 at...

journal_title：Frontiers in physiology

authors： Pereira-Ferrero VH,Lewis TG,Ferrero LGP,Duarte LT

更新日期：2019-09-03 00:00:00

abstract：:Early afterdepolarization (EAD) is known to cause lethal ventricular arrhythmias in long QT syndrome (LQTS). In this study, dynamical mechanisms of EAD formation in human ventricular myocytes (HVMs) were investigated using the mathematical model developed by ten Tusscher and Panfilov (Am J Physiol Heart Circ Physiol 2...

journal_title：Frontiers in physiology

authors： Kurata Y,Tsumoto K,Hayashi K,Hisatome I,Kuda Y,Tanida M

更新日期：2020-01-10 00:00:00

abstract：:The earliest humans relied on large quantities of metabolic energy from the oxidation of fatty acids to develop larger brains and bodies, prevent and reduce disease risk, extend longevity, in addition to other benefits. This was enabled through the consumption of a high fat and low-carbohydrate diet (LCD). Increased f...

journal_title：Frontiers in physiology

authors： Maffetone P,Laursen PB

更新日期：2020-04-02 00:00:00

abstract：:Background: Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) is highly effective in alleviating motor symptoms of Parkinson's disease (PD) which are not optimally controlled by dopamine replacement therapy. Clinical studies and reports suggest that STN-DBS may result in increased impulsivity and de novo impulse co...

journal_title：Frontiers in physiology

authors： Mandali A,Chakravarthy VS,Rajan R,Sarma S,Kishore A

更新日期：2016-11-29 00:00:00

abstract：:Objective: Ventricular remodeling is considered the basis of heart failure and is involved in myocardial fibrosis. This study aimed to assess perindopril and a galectin-3 inhibitor (modified citrus pectin, MCP) for their effects on ventricular remodeling and myocardial fibrosis in rabbits with ischemic heart failure. ...

journal_title：Frontiers in physiology

authors： Li S,Li S,Hao X,Zhang Y,Deng W

更新日期：2019-03-22 00:00:00

abstract：:While isolation of the pulmonary veins is firmly established as effective treatment for the majority of paroxysmal atrial fibrillation (AF) patients, there is recognition that patients with persistent AF have substrate for perpetuation of arrhythmia existing outside of the pulmonary veins. Various computational approa...

journal_title：Frontiers in physiology

authors： Stiles MK,Sanders P,Lau DH

更新日期：2018-09-18 00:00:00