Identification of Wolbachia-Responsive miRNAs in the Small Brown Planthopper, Laodelphax striatellus.

abstract：:Recently, we reported that Dahl salt-sensitive leptin receptor mutant (SSLepRmutant) rats exhibit dyslipidemia and renal lipid accumulation independent of hyperglycemia that progresses to chronic kidney disease (CKD). Therefore, in the current study, we examined the effects of gemfibrozil, a lipid-lowering drug (200 m...

journal_title：Frontiers in physiology

authors： Shields CA,Poudel B,McPherson KC,Brown AK,Ekperikpe US,Browning E,Sutton L,Cornelius DC,Williams JM

更新日期：2020-09-18 00:00:00

abstract：:Many studies have investigated the physiological response to microgravity in both astronauts and animals. However, while space agencies have sought to deploy more women on their missions; animal models rarely include females studies or comparisons between males and females. Therefore, we exposed adult female rats to 2...

journal_title：Frontiers in physiology

authors： Semple C,Riveros D,Nagy JA,Rutkove SB,Mortreux M

更新日期：2020-04-03 00:00:00

abstract：:Surface electromyography (sEMG) is a popular research tool in sport and rehabilitation sciences. Common study designs include the comparison of sEMG amplitudes collected from different muscles as participants perform various exercises and techniques under different loads. Based on such comparisons, researchers attempt...

journal_title：Frontiers in physiology

authors： Vigotsky AD,Halperin I,Lehman GJ,Trajano GS,Vieira TM

更新日期：2018-01-04 00:00:00

abstract：:There are animal species that have adapted to life at high altitude and hypobaric hypoxia conditions in the Andean highlands. One such species is the llama (Lama glama), which seem to have developed efficient protective mechanisms to avoid maladaptation resulting from chronic hypoxia, such as a resistance to the devel...

journal_title：Frontiers in physiology

authors： López V,Moraga FA,Llanos AJ,Ebensperger G,Taborda MI,Uribe E

更新日期：2018-05-29 00:00:00

abstract：:Background and Objective: It is widely accepted that there is an association between chronic obstructive pulmonary disease (COPD) and periodontitis. However, whether the periodontal status of the COPD patients is worse than that of the non-COPD subjects is seldom assessed. The findings currently available are inconsis...

journal_title：Frontiers in physiology

authors： Shi Q,Zhang B,Xing H,Yang S,Xu J,Liu H

更新日期：2018-01-25 00:00:00

abstract：:Coral reef communities are undergoing marked declines due to a variety of stressors including disease. The sea fan coral, Gorgonia ventalina, is a tractable study system to investigate mechanisms of immunity to a naturally occurring pathogen. Functional studies in Gorgonia ventalina immunity indicate that several key ...

journal_title：Frontiers in physiology

authors： Burge CA,Mouchka ME,Harvell CD,Roberts S

更新日期：2013-07-25 00:00:00

abstract：:Spinal muscular atrophy (SMA), amyotrophic lateral sclerosis (ALS), and spinal-bulbar muscular atrophy (SBMA) are devastating diseases characterized by the degeneration of motor neurons. Although the molecular causes underlying these diseases differ, recent findings have highlighted the contribution of intrinsic skele...

journal_title：Frontiers in physiology

authors： Boyer JG,Ferrier A,Kothary R

更新日期：2013-12-18 00:00:00

abstract：:A variety of biological networks can be modeled as logical or Boolean networks. However, a simplification of the reality to binary states of the nodes does not ease the difficulty of analyzing the dynamics of large, complex networks, such as signal transduction networks, due to the exponential dependence of the state ...

journal_title：Frontiers in physiology

authors： Pentzien T,Puniya BL,Helikar T,Matache MT

更新日期：2018-08-31 00:00:00

abstract：BACKGROUND:Recent findings strongly promoted the hypothesis that common pelvic gynecological diseases including endometriosis and ovarian neoplasia may develop de novo from ectopic endometrial-like glands and/or embryonic epithelial remnants. To verify the frequency, the anatomical localization and the phenotype of mis...

journal_title：Frontiers in physiology

authors： Bouquet de Jolinière J,Ayoubi JM,Lesec G,Validire P,Goguin A,Gianaroli L,Dubuisson JB,Feki A,Gogusev J

更新日期：2012-12-03 00:00:00

abstract：:The ubiquitin proteasome system (UPS) is a highly regulated mechanism of intracellular protein degradation and turnover. To evaluate the effect of crowding stress on the UPS in fish, grass carp (Ctenopharyngodon idellus) were randomly reared at low stocking density (LSD, 0.9 kg m-2) or high stocking density (HSD, 5.9 ...

journal_title：Frontiers in physiology

authors： Sun Y,Liang X,Chen J,Tang R,Li L,Li D

更新日期：2018-07-05 00:00:00

abstract：:Today, in silico studies and trial simulations already complement experimental approaches in pharmaceutical R&D and have become indispensable tools for decision making and communication with regulatory agencies. While biology is multiscale by nature, project work, and software tools usually focus on isolated aspects o...

journal_title：Frontiers in physiology

authors： Eissing T,Kuepfer L,Becker C,Block M,Coboeken K,Gaub T,Goerlitz L,Jaeger J,Loosen R,Ludewig B,Meyer M,Niederalt C,Sevestre M,Siegmund HU,Solodenko J,Thelen K,Telle U,Weiss W,Wendl T,Willmann S,Lippert J

更新日期：2011-02-24 00:00:00

abstract：:The goal here is to describe our current understanding of heme metabolism and the deleterious effects of "free" heme on immunological processes, endothelial function, systemic inflammation, and various end-organ tissues (e.g., kidney, lung, liver, etc.), with particular attention paid to the role of hemopexin (HPX). B...

journal_title：Frontiers in physiology

authors： Smith A,McCulloh RJ

更新日期：2015-06-30 00:00:00

abstract：:This review details the manner in which the central nervous system regulates metabolic homeostasis in normal weight and obese rodents and humans. It includes a review of the homeostatic contributions of neurons located in the hypothalamus, the midbrain and limbic structures, the pons and the medullary area postrema, n...

journal_title：Frontiers in physiology

authors： Smith JK

更新日期：2018-05-17 00:00:00

abstract：:Large-conductance calcium-activated potassium (BK) channels are currently considered as vital players in a variety of renal physiological processes. In podocytes, BK channels become active in response to stimuli that increase local cytosolic Ca(2+), possibly secondary to activation of slit diaphragm TRPC6 channels by ...

journal_title：Frontiers in physiology

authors： Tao J,Lan Z,Wang Y,Hei H,Tian L,Pan W,Zhang X,Peng W

更新日期：2016-06-21 00:00:00

abstract：:Carbon monoxide (CO) that is produced in a number of different mammalian tissues is now known to have significant effects on the cardiovascular system. These include: (i) vasodilation, (ii) changes in heart rate and strength of contractions, and (iii) modulation of autonomic nervous system input to both the primary pa...

journal_title：Frontiers in physiology

authors： Trenor B,Cardona K,Saiz J,Rajamani S,Belardinelli L,Giles WR

更新日期：2013-10-17 00:00:00

abstract：:Heart failure and frailty are clinical syndromes that present with overlapping phenotypic characteristics. Importantly, their co-presence is associated with increased mortality and morbidity. While mechanical and electrical device therapies for heart failure are vital for select patients with advanced stage disease, t...

journal_title：Frontiers in physiology

authors： Fung E,Hui E,Yang X,Lui LT,Cheng KF,Li Q,Fan Y,Sahota DS,Ma BHM,Lee JSW,Lee APW,Woo J

更新日期：2018-04-24 00:00:00

abstract：:Yellow genes are thought to be involved in the melanin biosynthetic pathway and play a crucial role in pigmentation reactions in insects. However, little research has been done on yellow genes in lepidopteran pests. To clarify the function of one of the yellow genes (yellow-y) in Spodoptera litura, we cloned the full-...

journal_title：Frontiers in physiology

authors： Liu XL,Han WK,Ze LJ,Peng YC,Yang YL,Zhang J,Yan Q,Dong SL

更新日期：2020-12-17 00:00:00

abstract：:A wide range of adipokines identified over the past years has allowed considering the white adipose tissue as a secretory organ closely integrated into overall physiological and metabolic control. Apelin, a ubiquitously expressed peptide was known to exert different physiological effects mainly on the cardiovascular s...

journal_title：Frontiers in physiology

authors： Bertrand C,Valet P,Castan-Laurell I

更新日期：2015-04-10 00:00:00

abstract：:Directed cell migration is essential all along an individual's life, from embryogenesis to tissue repair and cancer metastasis. Thus, due to its biomedical relevance, directed cell migration is currently under intense research. Directed cell migration has been shown to be driven by an assortment of external biasing cu...

journal_title：Frontiers in physiology

authors： Barriga EH,Theveneau E

更新日期：2020-11-25 00:00:00

abstract：:The main purpose of the present study was to investigate the effect of frequency, thereby increasing training volume, of resistance training on body composition, inflammation markers, lipid and glycemic profile in healthy older individuals (age range 65-75 year). Ninety-two healthy participants were randomly assigned ...

journal_title：Frontiers in physiology

authors： Ihalainen JK,Inglis A,Mäkinen T,Newton RU,Kainulainen H,Kyröläinen H,Walker S

更新日期：2019-02-01 00:00:00

abstract：:Finding an optimum for the cycling performance is not a trivial matter, since the literature shows the presence of many controversial aspects. In order to quantify different levels of performance, several indexes have been defined and used in many studies, reflecting variations in physiological and biomechanical facto...

journal_title：Frontiers in physiology

authors： Castronovo AM,Conforto S,Schmid M,Bibbo D,D'Alessio T

更新日期：2013-05-21 00:00:00

abstract：BACKGROUND:During caesarean section spinal anesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine. Phenylephrine is however reported to reduce the near infrared spectroscopy-determined frontal lobe oxygenation (ScO2) but whether that is the case for patients expo...

journal_title：Frontiers in physiology

authors： Foss VT,Christensen R,Rokamp KZ,Nissen P,Secher NH,Nielsen HB

更新日期：2014-03-03 00:00:00

abstract：:Immunity and cellular metabolism are tightly interconnected but it is not clear whether different pathogens elicit specific metabolic responses. To address this issue, we studied differential metabolic regulation in peripheral blood mononuclear cells (PBMCs) of healthy volunteers challenged by Candida albicans, Borrel...

journal_title：Frontiers in physiology

authors： Zhang X,Mardinoglu A,Joosten LAB,Kuivenhoven JA,Li Y,Netea MG,Groen AK

更新日期：2018-02-27 00:00:00

abstract：:A moderate hypoxic stimulus is considered a promising therapeutic modality for several pathological states including obesity. There is scientific evidence suggesting that when hypoxia and physical activity are combined, they could provide benefits for the obese population. The aim of the present study was to investiga...

journal_title：Frontiers in physiology

authors： Camacho-Cardenosa A,Camacho-Cardenosa M,Burtscher M,Martínez-Guardado I,Timon R,Brazo-Sayavera J,Olcina G

更新日期：2018-02-07 00:00:00

abstract：AIM:The aim of the present study was to analyze the response of vascular circulating microRNAs (miRNAs; miR-16, miR-21, miR-126) and the VEGF mRNA following an acute bout of HIIT and HVT in children. METHODS:Twelve healthy competitive young male cyclists (14.4 ± 0.8 years; 57.9 ± 9.4 ml·min(-1)·kg(-1) peak oxygen upta...

journal_title：Frontiers in physiology

authors： Kilian Y,Wehmeier UF,Wahl P,Mester J,Hilberg T,Sperlich B

更新日期：2016-03-14 00:00:00

abstract：Background:Spontaneously Hypertensive Rats (SHR) have chronically elevated blood pressures at 30 weeks of age (systolic: 191.0 ± 1.0, diastolic: 128.8 ± 0.9). However, despite this chronic malignant hypertension, SHR kidneys remain relatively free of pathology due to having an augmented myogenic constriction (MC). We h...

journal_title：Frontiers in physiology

authors： Nademi S,Lu C,Dickhout JG

更新日期：2020-07-22 00:00:00

abstract：:Drosophila melanogaster has served as an excellent genetic model to decipher the molecular basis of the circadian clock. Two key proteins, PERIOD (PER) and TIMELESS (TIM), are particularly well explored and a number of various arrhythmic, slow, and fast clock mutants have been identified in classical genetic screens. ...

journal_title：Frontiers in physiology

authors： Singh S,Giesecke A,Damulewicz M,Fexova S,Mazzotta GM,Stanewsky R,Dolezel D

更新日期：2019-12-03 00:00:00

abstract：:Regular exercise prevents lipid abnormalities and conditions such as diabetes mellitus, hypertension, and obesity; it considerably benefits sedentary individuals. However, individuals exhibit highly variable responses to exercise, probably due to genetic variations. Animal models are typically used to investigate the ...

journal_title：Frontiers in physiology

authors： Tung YT,Hsu YJ,Liao CC,Ho ST,Huang CC,Huang WC

更新日期：2019-09-18 00:00:00

abstract：:Severely affected patients with autonomic failure require pressor agents to counteract the blood pressure fall and improve presyncopal symptoms upon standing. Previous studies suggest that combination ergotamine and caffeine may be effective in the treatment of autonomic failure, but the efficacy of this drug has not ...

journal_title：Frontiers in physiology

authors： Arnold AC,Ramirez CE,Choi L,Okamoto LE,Gamboa A,Diedrich A,Raj SR,Robertson D,Biaggioni I,Shibao CA

更新日期：2014-07-24 00:00:00

abstract：:Giant clams live in symbiosis with extracellular zooxanthellae and display high rates of growth and shell formation (calcification) in light. Light-enhanced calcification requires an increase in the supply of Ca2+ to, and simultaneously an augmented removal of H+ from, the extrapallial fluid where shell formation occu...

journal_title：Frontiers in physiology

authors： Ip YK,Hiong KC,Goh EJK,Boo MV,Choo CYL,Ching B,Wong WP,Chew SF

更新日期：2017-10-10 00:00:00