Application of Patient-Specific Computational Fluid Dynamics in Coronary and Intra-Cardiac Flow Simulations: Challenges and Opportunities.

abstract：:Carbon monoxide (CO) that is produced in a number of different mammalian tissues is now known to have significant effects on the cardiovascular system. These include: (i) vasodilation, (ii) changes in heart rate and strength of contractions, and (iii) modulation of autonomic nervous system input to both the primary pa...

journal_title：Frontiers in physiology

authors： Trenor B,Cardona K,Saiz J,Rajamani S,Belardinelli L,Giles WR

更新日期：2013-10-17 00:00:00

abstract：:Aquaculture is a growing industry that is increasingly providing a sizable proportion of fishery products for human consumption. Dietary energy and temperature fluctuations affect fish health and may even trigger mortality, causing great losses in fish production during winter. To better understand this unproductive w...

journal_title：Frontiers in physiology

authors： Sánchez-Nuño S,Sanahuja I,Fernández-Alacid L,Ordóñez-Grande B,Fontanillas R,Fernández-Borràs J,Blasco J,Carbonell T,Ibarz A

更新日期：2018-07-17 00:00:00

abstract：:A sedentary lifestyle is associated with increased cardiovascular risk factors and reduced cardiac compliance when compared to a lifestyle that includes exercise training. Exercise training increases cardiac compliance in humans, but the mechanisms underlying this improvement are unknown. A major determinant of cardia...

journal_title：Frontiers in physiology

authors： Chung CS,Hiske MA,Chadha A,Mueller PJ

更新日期：2020-02-05 00:00:00

abstract：:The paired cranial sensory organs and peripheral nervous system of vertebrates arise from a thin strip of cells immediately adjacent to the developing neural plate. The neural plate border region comprises progenitors for four key populations of cells: neural plate cells, neural crest cells, the cranial placodes, and ...

journal_title：Frontiers in physiology

authors： Thawani A,Groves AK

更新日期：2020-12-07 00:00:00

abstract：:Glutathione (GSH) deficits have been observed in several mental or degenerative illness, and so has the metabolic syndrome. The impact of a decreased glucose metabolism on the GSH system is well-known, but the effect of decreased GSH levels on the energy metabolism is unclear. The aim of the present study was to inves...

journal_title：Frontiers in physiology

authors： Lavoie S,Steullet P,Kulak A,Preitner F,Do KQ,Magistretti PJ

更新日期：2016-04-21 00:00:00

abstract：:We examined how systemic blockade of type 1 angiotensin (AT(1)-) receptors affects reflex control of the circulation and the kidney. In conscious rabbits, the effects of candesartan on responses of systemic and renal hemodynamics and renal excretory function to acute hypoxia, mild hemorrhage, and plasma volume expansi...

journal_title：Frontiers in physiology

authors： Xu TB,Eppel GA,Head GA,Evans RG

更新日期：2011-07-19 00:00:00

abstract：:A Boolean model is a simple, discrete and dynamic model without the need to consider the effects at the intermediate levels. However, little effort has been made into constructing activation, inhibition, and protein decay networks, which could indicate the direct roles of a gene (or its synthesized protein) as an acti...

journal_title：Frontiers in physiology

authors： Chen L,Kulasiri D,Samarasinghe S

更新日期：2018-09-25 00:00:00

abstract：:[This corrects the article on p. 165 in vol. 7, PMID: 27242539.]. ...

journal_title：Frontiers in physiology

authors： Nielsen AL,Chen S,Fleischer SJ

更新日期：2017-08-11 00:00:00

abstract：PURPOSE:We investigated if oral ingestion of ibuprofen influenced leucocyte recruitment and infiltration following an acute bout of traditional resistance exercise Methods: Sixteen male subjects were divided into two groups that received the maximum over-the-counter dose of ibuprofen (1200mg d(-1)) or a similarly admin...

journal_title：Frontiers in physiology

authors： Vella L,Markworth JF,Paulsen G,Raastad T,Peake JM,Snow RJ,Cameron-Smith D,Russell AP

更新日期：2016-03-29 00:00:00

abstract：:The non-linear stress-strain behavior of uniaxially-stretched lung parenchyma is thought to be an emergent phenomenon arising from the ensemble behavior of its microscopic constituents. Such behavior includes the alignment and elongation of randomly oriented alveolar walls with initially flaccid fibers in the directio...

journal_title：Frontiers in physiology

authors： Bou Jawde S,Takahashi A,Bates JHT,Suki B

更新日期：2020-02-25 00:00:00

abstract：Introduction:Obstructive sleep apnea (OSA) has been associated with non-dipping blood pressure (BP). The precise mechanism is still under investigation, but repetitive oxygen desaturation and arousal induced sleep fragmentation are considered the main contributors. Methods:We analyzed beat-to-beat measurements of hemo...

journal_title：Frontiers in physiology

authors： Staats R,Barros I,Fernandes D,Grencho D,Reis C,Matos F,Valença J,Marôco J,de Almeida AB,Bárbara C

更新日期：2020-03-13 00:00:00

abstract：:In Bombyx mori, polar body nuclei are observed until 9 h after egg lying, however, the fate of polar body nuclei remains unclear. To examine the fate of polar body nuclei, we employed a mutation of serosal cell pigmentation, pink-eyed white egg (pe). The heterozygous pe/+ (pe) females produced black serosal cells in w...

journal_title：Frontiers in physiology

authors： Sakai H,Yokoyama T,Abe H,Fujii T,Suzuki MG

更新日期：2013-09-03 00:00:00

abstract：:The aim of this study was to investigate the effects of two consecutive Crossfit® training sessions (24 h apart) designed to enhance work-capacity that involved both cardiovascular and muscular exercises on cytokines, muscle power, blood lactate and glucose. Nine male members of the CrossFit® community (age 26.7 ± 6.6...

journal_title：Frontiers in physiology

authors： Tibana RA,de Almeida LM,Frade de Sousa NM,Nascimento Dda C,Neto IV,de Almeida JA,de Souza VC,Lopes Mde F,Nobrega Ode T,Vieira DC,Navalta JW,Prestes J

更新日期：2016-06-28 00:00:00

abstract：:Sepsis is a systemic inflammatory disease with infection, and autophagy has been shown to play an important role in sepsis. This review summarizes the main regulatory mechanisms of autophagy in sepsis and its latest research. Recent studies have shown that autophagy can regulate innate immune processes and acquired im...

journal_title：Frontiers in physiology

authors： Yin X,Xin H,Mao S,Wu G,Guo L

更新日期：2019-08-23 00:00:00

abstract：:We have been able to reduce substantially patient pool heterogeneity by identifying phenotypic markers that allow the researcher to stratify chronic fatigue syndrome (CFS) patients into subgroups. To date, we have shown that stratifying based on the presence or absence of comorbid psychiatric diagnosis leads to a grou...

journal_title：Frontiers in physiology

authors： Natelson BH

更新日期：2013-05-20 00:00:00

abstract：:Background: Pressure unloading induces the regression of left ventricular myocardial hypertrophy (LVH). Recent findings indicate that pharmacological activation of the soluble guanylate cyclase (sGC) - cyclic guanosine monophosphate (cGMP) pathway may also exert reverse-remodeling properties in the myocardium. Therefo...

journal_title：Frontiers in physiology

authors： Ruppert M,Korkmaz-Icöz S,Li S,Brlecic P,Németh BT,Oláh A,Horváth EM,Veres G,Pleger S,Grabe N,Merkely B,Karck M,Radovits T,Szabó G

更新日期：2019-01-08 00:00:00

abstract：:Patients undergoing hyperbaric oxygen therapy and divers engaged in underwater activity are at risk of central nervous system oxygen toxicity. An algorithm for predicting CNS oxygen toxicity in active underwater diving has been published previously, but not for humans at rest. Using a procedure similar to that employe...

journal_title：Frontiers in physiology

authors： Aviner B,Arieli R,Yalov A

更新日期：2020-08-17 00:00:00

abstract：:The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders. In brief, the sliding movement of fluorescence-labeled actin filaments on myosin motor proteins is recorded, and the sliding velocity ...

journal_title：Frontiers in physiology

authors： Bopp N,Scheid LM,Fink RHA,Rohr K

更新日期：2019-03-27 00:00:00

abstract：:Adaptation of arm reaching in a novel force field involves co-contraction of upper limb muscles, but it is not known how the co-ordination of multiple muscle activation is orchestrated. We have used intermuscular coherence (IMC) to test whether a coherent intermuscular coupling between muscle pairs is responsible for ...

journal_title：Frontiers in physiology

authors： Pizzamiglio S,De Lillo M,Naeem U,Abdalla H,Turner DL

更新日期：2017-01-09 00:00:00

abstract：:The purpose of this study was to compare the effects of two similar high-intensity intermittent exercises (HIIE) but different volume 1.25 km (HIIE1.25) and 2.5 km (HIIE2.5) on inflammatory and BDNF responses. Ten physically active male subjects (age 25.22 ± 1.74 years, body mass 78.98 ± 7.31 kg, height 1.78 ± 0.06 m,...

journal_title：Frontiers in physiology

authors： Cabral-Santos C,Castrillón CI,Miranda RA,Monteiro PA,Inoue DS,Campos EZ,Hofmann P,Lira FS

更新日期：2016-11-04 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) not only play essential roles in bone development but also are involved in embryonic growth, organogenesis cell proliferation and differentiation. However, the previous studies on the functions of shellfish BMPs genes are still very limited. To better understand its molecular structu...

journal_title：Frontiers in physiology

authors： Zhao J,Cui B,Yao H,Lin Z,Dong Y

更新日期：2020-08-28 00:00:00

abstract：:The present study aims (1) to evaluate ratings of perceived exertion (RPE) and corresponding intensities during a maximal graded cycling test and (2) to determine the effects of 6 weeks of supramaximal cycling exercise (SCE) intervention on RPE and associated physiological factors in young and older sedentary groups. ...

journal_title：Frontiers in physiology

authors： Jabbour G,Majed L

更新日期：2018-10-25 00:00:00

abstract：UNLABELLED:Limitations of current methods: Normalization of resting energy expenditure (REE) for body composition using the 2-compartment model fat mass (FM), and fat-free mass (FFM) has inherent limitations for the interpretation of REE and may lead to erroneous conclusions when comparing people with a wide range of a...

journal_title：Frontiers in physiology

authors： Bosy-Westphal A,Braun W,Schautz B,Müller MJ

更新日期：2013-03-25 00:00:00

abstract：:To understand dynamic changes in polyamines (PAs) forms and components of polyamine metabolism in zoysiagrass (Zoysia japonica Steud.) response to salt stress with exogenous spermidine (Spd) application, two Chinese zoysia cultivars, z081 and z057, were exposed to sodium chloride stress for 2, 4, 6, and 8 days. The z0...

journal_title：Frontiers in physiology

authors： Li S,Cui L,Zhang Y,Wang Y,Mao P

更新日期：2017-04-06 00:00:00

abstract：:Alpine skiing has been an Olympic event since the first Winter Games in 1936. Nowadays, skiers compete in four main events: slalom, giant slalom, super-G and downhill. Here, we present an update on the biomechanics of alpine ski racers and their equipment. The technical and tactical ability of today's world-class skie...

journal_title：Frontiers in physiology

authors： Supej M,Holmberg HC

更新日期：2019-02-20 00:00:00

abstract：:There are two primary components that produce pulmonary arterial hypertension (PAH); aberrant structural changes (smooth muscle cell proliferation, smooth muscle cell hypertrophy, and the deposition of matrix proteins within the media of pulmonary arterial vessels), and excess vasoconstriction. However, in PAH, the ta...

journal_title：Frontiers in physiology

authors： Lyle MA,Davis JP,Brozovich FV

更新日期：2017-08-23 00:00:00

abstract：:The senescence of vascular smooth muscle cells (VSMCs) has been implicated as a causal pro-inflammatory mechanism for cardiovascular disease development and progression of atherosclerosis, the instigator of ischemic heart disease. Contemporary limitations related to studying this cellular population and senescence-rel...

journal_title：Frontiers in physiology

authors： Stojanović SD,Fuchs M,Kunz M,Xiao K,Just A,Pich A,Bauersachs J,Fiedler J,Sedding D,Thum T

更新日期：2020-05-25 00:00:00

abstract：Introduction:Adenosine is an ATP derivative that is strongly implicated in the cardiovascular adaptive response to exercise. In this study, we hypothesized that during exercise the hyperemia, commonly observed during exercise in air, was counteracted by the downregulation of the adenosinergic pathway during hyperoxic e...

journal_title：Frontiers in physiology

authors： Boussuges A,Rives S,Marlinge M,Chaumet G,Vallée N,Guieu R,Gavarry O

更新日期：2020-02-11 00:00:00

abstract：:Background: Chronic infection with HBV (CHB) or HCV (CHC) is the most common chronic viral hepatitis that can lead to cirrhosis and hepatocellular carcinoma in humans, their infections have distinct pathogenic processes, however, little is known about the difference of glycoprotein glycopatterns in serum between hepat...

journal_title：Frontiers in physiology

authors： Qin X,Guo Y,Du H,Zhong Y,Zhang J,Li X,Yu H,Zhang Z,Jia Z,Li Z

更新日期：2017-08-21 00:00:00

abstract：:The pre-occlusal eruption brings the molars into functional occlusion and initiates tensional strains during mastication. We hypothesized that upon establishment of occlusal contact, the periodontal ligament (PDL) undergoes cell and extracellular matrix maturation to adapt to this mechanical function. The PDL of 12 Wi...

journal_title：Frontiers in physiology

authors： Denes BJ,Ait-Lounis A,Wehrle-Haller B,Kiliaridis S

更新日期：2020-03-05 00:00:00