β-adrenergic receptor responsiveness in aging heart and clinical implications.

abstract：:Control of cell-cell coordination and communication is regulated by several factors, including paracrine and autocrine release of biomolecules, and direct exchange of soluble factors between cells through gap junction channels. Additionally, hemichannels also participate in cell-cell coordination through the release o...

journal_title：Frontiers in physiology

authors： Calderón JF,Retamal MA

更新日期：2016-11-25 00:00:00

abstract：:Cycling test such Wingate anaerobic test (WAnT) is used to measure anaerobic power (AP), but not anaerobic capacity (AC, i.e., the metabolic energy demand). However, in sports that do not involve cycling movements (Karate), the continuous jump for 30 s (vertical jumps for 30 s) has been extensively used to measure ana...

journal_title：Frontiers in physiology

authors： Čular D,Ivančev V,Zagatto AM,Milić M,Beslija T,Sellami M,Padulo J

更新日期：2018-05-15 00:00:00

abstract：:The effect of training status on post-exercise flow-mediated dilation (FMD) is not well characterized. We tested the hypothesis that the more trained the subjects, the lower the reduction in FMD after an acute bout of aerobic exercise. Forty-seven men (mean ± SD, age: 20.1 ± 1.2 years, body mass: 75.5 ± 5.1 kg, height...

journal_title：Frontiers in physiology

authors： Kapilevich LV,Kologrivova VV,Zakharova AN,Mourot L

更新日期：2020-05-08 00:00:00

abstract：:As arteries become stiffer with aging, reflected waves move faster and augment late systolic pressure. Few studies have described the age-related changes in both peripheral and central systolic blood pressures in populations. We investigated the age dependency of peripheral (pSBP) and central (cSBP) systolic pressure ...

journal_title：Frontiers in physiology

authors： Wojciechowska W,Li Y,Stolarz-Skrzypek K,Kawecka-Jaszcz K,Staessen JA,Wang JG,European Project on Genes in Hypertension and the JingNing Study Investigators.

更新日期：2012-06-15 00:00:00

abstract：:As part of the ZOOMICS project, we set out to investigate common and diverging metabolic traits in the blood metabolome across various species by taking advantage of recent developments in high-throughput metabolomics. Here we provide the first comparative metabolomics analysis of fresh and stored human (n = 21, 10 ma...

journal_title：Frontiers in physiology

authors： Bertolone L,Shin HK,Stefanoni D,Baek JH,Gao Y,Morrison EJ,Nemkov T,Thomas T,Francis RO,Hod EA,Zimring JC,Yoshida T,Karafin M,Schwartz J,Hudson KE,Spitalnik SL,Buehler PW,D'Alessandro A

更新日期：2020-10-23 00:00:00

abstract：:Cigarette smoking causes chronic lung inflammation that is mainly regulated by redox-sensitive pathways. Our previous studies have demonstrated that cigarette smoke (CS) activates reactive oxygen species (ROS)-sensitive mitogen-activated protein kinases (MAPKs)/nuclear factor-κB (NF-κB) signaling resulting in inductio...

journal_title：Frontiers in physiology

authors： Liu MH,Lin AH,Lu SH,Peng RY,Lee TS,Kou YR

更新日期：2014-11-14 00:00:00

abstract：:Singlet oxygen generated in a type II photodynamic action, due to its limited lifetime (1 μs) and reactive distance (<10 nm), could regulate live cell function nanoscopically. The genetically-encoded protein photosensitizers (engineered fluorescent proteins such as KillerRed, TagRFP, and flavin-binding proteins such a...

journal_title：Frontiers in physiology

authors： Jiang HN,Li Y,Cui ZJ

更新日期：2017-04-04 00:00:00

abstract：:Antibiotic resistance is a major issue in animal industries and antibiotic-free alternatives are needed to treat infectious diseases and improve performance of pigs. Plant extracts have been suggested as a potential solution. The present study was conducted to investigate the effects of Astragalus polysaccharides (Aps...

journal_title：Frontiers in physiology

authors： Yang CM,Han QJ,Wang KL,Xu YL,Lan JH,Cao GT

更新日期：2019-04-12 00:00:00

abstract：:Leucine-rich repeat containing protein 10 (LRRC10) is a cardiomyocyte-specific member of the Leucine-rich repeat containing (LRRC) protein superfamily with critical roles in cardiac function and disease pathogenesis. Recent studies have identified LRRC10 mutations in human idiopathic dilated cardiomyopathy (DCM) and L...

journal_title：Frontiers in physiology

authors： Brody MJ,Lee Y

更新日期：2016-08-03 00:00:00

abstract：:Voltage gated potassium channels (KV) are membrane proteins that allow selective flow of K+ ions in a voltage-dependent manner. These channels play an important role in several excitable cells as neurons, cardiomyocytes, and vascular smooth muscle. Over the last 20 years, it has been shown that omega-3 polyunsaturated...

journal_title：Frontiers in physiology

authors： Moreno C,de la Cruz A,Valenzuela C

更新日期：2016-11-24 00:00:00

abstract：:γ-Aminobutyric Acid (GABA) and its receptors, GABAA,B,C, are expressed in several locations along the gastrointestinal tract. Nevertheless, a role for GABA in enteric synaptic transmission remains elusive. In this study, we characterized the expression and function of GABA in the myenteric plexus of the mouse ileum. A...

journal_title：Frontiers in physiology

authors： Koussoulas K,Swaminathan M,Fung C,Bornstein JC,Foong JPP

更新日期：2018-02-13 00:00:00

abstract：:Sarcopenia is the age-related progressive loss of skeletal muscle mass and strength finally leading to poor physical performance. Impaired myogenesis contributes to the pathogenesis of sarcopenia, while mitochondrial dysfunctions are thought to play a primary role in skeletal muscle loss during aging. Here we studied ...

journal_title：Frontiers in physiology

authors： Belli R,Bonato A,De Angelis L,Mirabilii S,Ricciardi MR,Tafuri A,Molfino A,Leigheb M,Costelli P,Caruso M,Muscaritoli M,Ferraro E

更新日期：2019-07-10 00:00:00

abstract：:Fractal phenomena can be found in numerous scientific areas including neuroscience. Fractals are structures, in which the whole has the same shape as its parts. A specific structure known as pink noise (also called fractal or 1/f noise) is one key fractal manifestation, exhibits both stability and adaptability, and ca...

journal_title：Frontiers in physiology

authors： Akhrif A,Romanos M,Domschke K,Schmitt-Boehrer A,Neufang S

更新日期：2018-10-04 00:00:00

abstract：:The free-fall of orbital spaceflight effectively removes the gravitational vector used as a primary spatial orientation reference on Earth. Sustained absence of this reference drives adaptive changes in the internal perception-action models of the central nervous system (CNS), most notably in the processing of the ves...

journal_title：Frontiers in physiology

authors： Ozdemir RA,Goel R,Reschke MF,Wood SJ,Paloski WH

更新日期：2018-11-27 00:00:00

abstract：:The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders. In brief, the sliding movement of fluorescence-labeled actin filaments on myosin motor proteins is recorded, and the sliding velocity ...

journal_title：Frontiers in physiology

authors： Bopp N,Scheid LM,Fink RHA,Rohr K

更新日期：2019-03-27 00:00:00

abstract：:Left ventricular (LV) myocardial dysfunction occurs after myocardial infarction (MI) is associated with the location, infarct size, and transmurality degrees of MI. The myocardial strain is a sensitive index used for the quantification of myocardium dysfunction. This study used Tissue-Tracking to evaluate whether the ...

journal_title：Frontiers in physiology

authors： Li S,Zhao L,Lu A,Tian J,Gong L,Ma X

更新日期：2020-12-10 00:00:00

abstract：:To determine the level of hypoxia from which muscle activation (MA) is reduced during incremental exercise to exhaustion (IE), and the role played by PIO2 in this process, ten volunteers (21 ± 2 years) performed four IE in severe acute hypoxia (SAH) (PIO2 = 73 mmHg). Upon exhaustion, subjects were asked to continue ex...

journal_title：Frontiers in physiology

authors： Torres-Peralta R,Losa-Reyna J,Morales-Alamo D,González-Izal M,Pérez-Suárez I,Ponce-González JG,Izquierdo M,Calbet JA

更新日期：2016-08-17 00:00:00

abstract：:Finding an optimum for the cycling performance is not a trivial matter, since the literature shows the presence of many controversial aspects. In order to quantify different levels of performance, several indexes have been defined and used in many studies, reflecting variations in physiological and biomechanical facto...

journal_title：Frontiers in physiology

authors： Castronovo AM,Conforto S,Schmid M,Bibbo D,D'Alessio T

更新日期：2013-05-21 00:00:00

abstract：:The purpose of this study was to examine the effects of a short-term ketogenic diet (KD) on body composition and cardiorespiratory fitness (CRF) in overweight/obese Chinese females. Twenty young females [age: 21.0 ± 3.7 years, weight: 65.5 ± 7.7 kg, body mass index (BMI): 24.9 ± 2.7 kg⋅m-2] consumed 4 weeks of a norma...

journal_title：Frontiers in physiology

authors： Kong Z,Sun S,Shi Q,Zhang H,Tong TK,Nie J

更新日期：2020-07-28 00:00:00

abstract：:Surface electromyography (sEMG) is a popular research tool in sport and rehabilitation sciences. Common study designs include the comparison of sEMG amplitudes collected from different muscles as participants perform various exercises and techniques under different loads. Based on such comparisons, researchers attempt...

journal_title：Frontiers in physiology

authors： Vigotsky AD,Halperin I,Lehman GJ,Trajano GS,Vieira TM

更新日期：2018-01-04 00:00:00

abstract：:The fluid transport and mixing induced by beating cilia, present in the bronchial airways, are studied using a coupled lattice Boltzmann-Immersed Boundary solver. This solver allows the simulation of both single and multi-component fluid flows around moving solid boundaries. The cilia are modeled by a set of Lagrangia...

journal_title：Frontiers in physiology

authors： Chateau S,D'Ortona U,Poncet S,Favier J

更新日期：2018-03-06 00:00:00

abstract：:Distal arthrogryposis (DA) is a skeletal muscle disorder which can be classified under a broader term as Arthrogryposis multiplex contractures. DA is characterized by the presence of joint contractures at various parts of the body, particularly in distal extremities. It is identified as an autosomal dominant and a rar...

journal_title：Frontiers in physiology

authors： Desai D,Stiene D,Song T,Sadayappan S

更新日期：2020-06-25 00:00:00

abstract：:In this paper, we computationally generate hypotheses for dose-finding studies in the context of desynchronizing neuromodulation techniques. Abnormally strong neuronal synchronization is a hallmark of several brain disorders. Coordinated Reset (CR) stimulation is a spatio-temporally patterned stimulation technique tha...

journal_title：Frontiers in physiology

authors： Manos T,Zeitler M,Tass PA

更新日期：2018-04-12 00:00:00

abstract：:Increasing water CO2, aquatic hypercapnia, leads to higher physiological pCO2 levels in fish, resulting in an acidosis and compensatory acid-base regulatory response. Senegalese sole is currently farmed in super-intensive recirculating water systems where significant accumulation of CO2 in the water may occur. Moreove...

journal_title：Frontiers in physiology

authors： Machado M,Arenas F,Svendsen JC,Azeredo R,Pfeifer LJ,Wilson JM,Costas B

更新日期：2020-01-31 00:00:00

abstract：:Aim: The aim of the present study was to determine the validity of position, distance traveled and instantaneous speed of team sport players as measured by a commercially available local positioning system (LPS) during indoor use. In addition, the study investigated how the placement of the field of play relative to t...

journal_title：Frontiers in physiology

authors： Luteberget LS,Spencer M,Gilgien M

更新日期：2018-04-04 00:00:00

abstract：:Background: Atherosclerotic carotid intima-media thickness (IMT) may be associated with alterations in the sensitivity of carotid baroreceptors. The aim of this study was to investigate the association between carotid IMT and the autonomic modulation of heart rate variability (HRV). Methods: A total of 101 subjects we...

journal_title：Frontiers in physiology

authors： Pereira VL Jr,Dobre M,Dos Santos SG,Fuzatti JS,Oliveira CR,Campos LA,Brateanu A,Baltatu OC

更新日期：2017-04-26 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle. Mitochondrial dysfunction is a well-known pathological feature of DMD. However, whether mitochondrial dysfunction occurs before muscle fiber damage in DMD pathology is not well known. Furthermore, the impact upon heterozygous femal...

journal_title：Frontiers in physiology

authors： Moore TM,Lin AJ,Strumwasser AR,Cory K,Whitney K,Ho T,Ho T,Lee JL,Rucker DH,Nguyen CQ,Yackly A,Mahata SK,Wanagat J,Stiles L,Turcotte LP,Crosbie RH,Zhou Z

更新日期：2020-06-19 00:00:00

abstract：:Being the central metabolic organ of vertebrates, the liver possesses the largest repertoire of metabolic enzymes among all tissues and organs. Almost all metabolic pathways are resident in the parenchymal cell, hepatocyte, but the pathway capacities may largely differ depending on the localization of hepatocytes with...

journal_title：Frontiers in physiology

authors： Berndt N,Holzhütter HG

更新日期：2018-12-12 00:00:00

abstract：:Mild normobaric hypoxia (NH) and modest exercise have multiple beneficial effects on health, but the changes in physiological function induced by NH and/or exercise remain unclear. The purpose of this investigation was to examine the specific effects of NH and/or exercise on cardiac function and myocardial structure a...

journal_title：Frontiers in physiology

authors： Li QF,Wang H,Zheng L,Yang F,Li HZ,Li JX,Cheng D,Lu K,Liu Y

更新日期：2020-01-21 00:00:00

abstract：:Eccentric loading is an effective stimulus for muscle hypertrophy and strength gains, however, the effect of lengthening velocity is under debate. The purpose of the current study was to investigate the influence of muscle lengthening velocity during eccentric training on muscle hypertrophy and strength gains at a giv...

journal_title：Frontiers in physiology

authors： Marzilger R,Bohm S,Mersmann F,Arampatzis A

更新日期：2019-07-31 00:00:00