High-Intensity Interval Training: A Potential Exercise Countermeasure During Human Spaceflight.

abstract：:Neointimal hyperplasia is amongst the major causes of failure of bypass grafts. The disease progression varies from patient to patient due to a range of different factors. In this paper, a mathematical model will be used to understand neointimal hyperplasia in individual patients, combining information from biological...

journal_title：Frontiers in physiology

authors： Donadoni F,Pichardo-Almarza C,Bartlett M,Dardik A,Homer-Vanniasinkam S,Díaz-Zuccarini V

更新日期：2017-04-18 00:00:00

abstract：:Skeletal muscle is a main target of insulin action that plays a pivotal role in postprandial glucose disposal. Importantly, skeletal muscle insulin sensitivity relates inversely with pancreatic insulin secretion, which prompted the hypothesis of the existence of a skeletal muscle-pancreas crosstalk mediated through an...

journal_title：Frontiers in physiology

authors： Mizgier ML,Fernández-Verdejo R,Cherfan J,Pinget M,Bouzakri K,Galgani JE

更新日期：2019-08-08 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fphys.2020.00302.]. ...

journal_title：Frontiers in physiology

authors： Semple C,Riveros D,Nagy JA,Rutkove SB,Mortreux M

更新日期：2020-07-03 00:00:00

abstract：:The luminal endoplasmic reticulum (ER) protein of 29 kDa (ERp29) is a ubiquitously expressed cellular agent with multiple critical roles. ERp29 regulates the biosynthesis and trafficking of several transmembrane and secretory proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR), the epith...

journal_title：Frontiers in physiology

authors： Brecker M,Khakhina S,Schubert TJ,Thompson Z,Rubenstein RC

更新日期：2020-09-08 00:00:00

abstract：Background:Sickle cell disease (SCD) patients with asthma have an increased rate of vaso-occlusive crisis (VOC) and acute chest syndrome (ACS) episodes when compared to those without asthma. We hypothesized that either asthma diagnosis or bronchodilator treatment might aggravate SCD via their modulating effect on the a...

journal_title：Frontiers in physiology

authors： Bokov P,El Jurdi H,Denjoy I,Peiffer C,Medjahdi N,Holvoet L,Benkerrou M,Delclaux C

更新日期：2020-02-26 00:00:00

abstract：:Background: RNase A (the bovine equivalent to human RNase 1) and RNase 5 (angiogenin) are two closely related ribonucleases. RNase 5 is described as a powerful angiogenic factor. Whether RNase A shares the same angiogenic characteristic, or interferes with vessel growth as demonstrated for arteriogenesis, has never be...

journal_title：Frontiers in physiology

authors： Lasch M,Kumaraswami K,Nasiscionyte S,Kircher S,van den Heuvel D,Meister S,Ishikawa-Ankerhold H,Deindl E

更新日期：2020-11-06 00:00:00

abstract：:Fibrosis is intimately linked to wound healing and is one of the largest causes of wound-related morbidity. While scar formation is the normal and inevitable outcome of adult mammalian cutaneous wound healing, scarring varies widely between different anatomical sites. The spectrum of craniofacial wound healing spans a...

journal_title：Frontiers in physiology

authors： desJardins-Park HE,Mascharak S,Chinta MS,Wan DC,Longaker MT

更新日期：2019-03-29 00:00:00

abstract：:An early event in atherogenesis is the recruitment and infiltration of circulating monocytes and macrophage activation in the subendothelial space. Atherosclerosis subsequently progresses as a unresolved inflammatory disease, particularly in hypercholesterolemic conditions. Although physical exercise training has been...

journal_title：Frontiers in physiology

authors： Rentz T,Wanschel ACBA,de Carvalho Moi L,Lorza-Gil E,de Souza JC,Dos Santos RR,Oliveira HCF

更新日期：2020-11-23 00:00:00

abstract：:Genetically modified mice provide a number of models for studying cardiac channelopathies related to cardiac Na(+) channel (SCN5A) abnormalities. We review key pathophysiological features in these murine models that may underlie clinical features observed in sinus node dysfunction and progressive cardiac conduction di...

journal_title：Frontiers in physiology

authors： Huang CL,Lei L,Matthews GD,Zhang Y,Lei M

更新日期：2012-07-06 00:00:00

abstract：:Human diseases have been investigated in the context of single genes as well as complex networks of genes. Though single gene approaches have been extremely successful in the past, most human diseases are complex and better characterized by multiple interacting genes commonly known as networks or pathways. With the ad...

journal_title：Frontiers in physiology

authors： Sahoo D

更新日期：2012-07-23 00:00:00

abstract：:A variety of biological networks can be modeled as logical or Boolean networks. However, a simplification of the reality to binary states of the nodes does not ease the difficulty of analyzing the dynamics of large, complex networks, such as signal transduction networks, due to the exponential dependence of the state ...

journal_title：Frontiers in physiology

authors： Pentzien T,Puniya BL,Helikar T,Matache MT

更新日期：2018-08-31 00:00:00

abstract：:Prior peripheral hypoxia induced via remote ischemic preconditioning (IPC) can improve physical performance in male athletes through improved O2 delivery and utilization. Since females may have an innate protective mechanism against ischemia-reperfusion injury, and since muscle metabolism during contraction differs be...

journal_title：Frontiers in physiology

authors： Paradis-Deschênes P,Joanisse DR,Billaut F

更新日期：2017-01-05 00:00:00

abstract：:Muscle quality and the physiological condition of fish are affected greatly by the culture environment. In aquaculture ponds, a bio-floating bed planted with vegetation is often used to improve water quality. This study investigated the growth and muscle quality of grass carp (Ctenopharyngodon idellus) cultured in pon...

journal_title：Frontiers in physiology

authors： Zhang X,Wang J,Tang R,He X,Li L,Takagi Y,Li D

更新日期：2019-05-31 00:00:00

abstract：:In addition to its roles in the maintenance of interstitial fluid homeostasis and immunosurveillance, the lymphatic system has a critical role in regulating transport of dietary lipids to the blood circulation. Recent work within the past two decades has identified an important relationship between lymphatic dysfuncti...

journal_title：Frontiers in physiology

authors： Norden PR,Kume T

更新日期：2020-05-05 00:00:00

abstract：Introduction:Obstructive sleep apnea (OSA) has been associated with non-dipping blood pressure (BP). The precise mechanism is still under investigation, but repetitive oxygen desaturation and arousal induced sleep fragmentation are considered the main contributors. Methods:We analyzed beat-to-beat measurements of hemo...

journal_title：Frontiers in physiology

authors： Staats R,Barros I,Fernandes D,Grencho D,Reis C,Matos F,Valença J,Marôco J,de Almeida AB,Bárbara C

更新日期：2020-03-13 00:00:00

abstract：:The in vitro motility assay (IVMA) is a powerful tool commonly used in basic muscle research and for drug screenings with the aim to find treatment options for neuromuscular disorders. In brief, the sliding movement of fluorescence-labeled actin filaments on myosin motor proteins is recorded, and the sliding velocity ...

journal_title：Frontiers in physiology

authors： Bopp N,Scheid LM,Fink RHA,Rohr K

更新日期：2019-03-27 00:00:00

abstract：:Background: The possibility of non-invasively assessing load-independent parameters characterizing cardiac function is of high clinical value. Typically, these parameters are assessed during resting conditions. However, for diagnostic purposes, the parameter behavior across a physiologically relevant range of heart ra...

journal_title：Frontiers in physiology

authors： Casas B,Viola F,Cedersund G,Bolger AF,Karlsson M,Carlhäll CJ,Ebbers T

更新日期：2018-10-30 00:00:00

abstract：:Heat acclimation by post-exercise hot water immersion (HWI) on six consecutive days reduces thermal strain and improves exercise performance during heat stress. However, the retention of adaptations by this method remains unknown. Typically, adaptations to short-term, exercise-heat-acclimation (<7 heat exposures) deca...

journal_title：Frontiers in physiology

authors： Zurawlew MJ,Mee JA,Walsh NP

更新日期：2019-08-28 00:00:00

abstract：PURPOSE:Breathlessness is a complex set of symptoms that are comprised of both sensory and affective (emotional) dimensions. While ventilation is now understood to be a potential limiter to performance in highly-trained individuals, the contribution of breathlessness-anxiety in those nearing maximal ventilation during ...

journal_title：Frontiers in physiology

authors： Faull OK,Cox PJ,Pattinson KT

更新日期：2016-06-16 00:00:00

abstract：:Coronary microembolization (CME) is an important clinical problem, and it is related to poor outcome. The specific molecular mechanisms of CME are not fully understood. In the present study, we established a mice model of CME. Isobaric tags for relative and absolute quantitation (iTRAQ) and liquid chromatography coupl...

journal_title：Frontiers in physiology

authors： Chen A,Chen Z,Xia Y,Lu D,Jia J,Hu K,Sun A,Zou Y,Qian J,Ge J

更新日期：2018-09-19 00:00:00

abstract：:The discus fish (Symphysodon aequifasciatus) is an ornamental fish that is well-known around the world. In artificial reproduction, they must be matched by one male and one female, whereas phenotype investigation indicated that there are no significant differences in appearance between males and females, which causes ...

journal_title：Frontiers in physiology

authors： Fu Y,Xu Z,Wen B,Gao J,Chen Z

更新日期：2020-08-11 00:00:00

abstract：:The search for new antihypertensive drugs has grown in recent years because of high rate of morbidity among hypertensive patients and several side effects that are associated with the first-line medications. The current study sought to investigate the antihypertensive effect of a newly synthesized pyrazole derivative ...

journal_title：Frontiers in physiology

authors： Trindade NR,Lopes PR,Naves LM,Fajemiroye JO,Alves PH,Amaral NO,Lião LM,Rebelo ACS,Castro CH,Braga VA,Menegatti R,Pedrino GR

更新日期：2018-08-07 00:00:00

abstract：:Background: The short-term benefits of aerobic and resistance exercise in subjects affected by Peripheral Arterial Disease (PAD) are scarcely examined in interaction. This study aimed to identify the effects of combined aerobic and resistance exercise programs on walking performance compared with isolated aerobic exer...

journal_title：Frontiers in physiology

authors： Machado I,Sousa N,Paredes H,Ferreira J,Abrantes C

更新日期：2020-01-08 00:00:00

abstract：:The sterile insect technique (SIT) may reduce pest populations by allowing sufficient amount of irradiation-induced sterile males to mate with wild females whilst maintaining mating ability comparable to wild males. Although the SIT methods are well understood, the optimal sterilizing dose and processing development s...

journal_title：Frontiers in physiology

authors： Cai J,Yang H,Shi S,Zhong G,Yi X

更新日期：2018-02-20 00:00:00

abstract：Background:Heart transplant is the gold standard therapy for patients with advanced heart failure. Over 5,500 heart transplants are performed every year worldwide. Cardiac allograft vasculopathy (CAV) is a common complication post-heart transplant which reduces survival and often necessitates heart retransplantation. P...

journal_title：Frontiers in physiology

authors： Irion CI,Dunkley JC,John-Williams K,Condor Capcha JM,Shehadeh SA,Pinto A,Loebe M,Webster KA,Brozzi NA,Shehadeh LA

更新日期：2020-08-13 00:00:00

abstract：:Sulfur is both crucial to life and a potential threat to health. While colonic sulfur metabolism mediated by eukaryotic cells is relatively well studied, much less is known about sulfur metabolism within gastrointestinal microbes. Sulfated compounds in the colon are either of inorganic (e.g., sulfates, sulfites) or or...

journal_title：Frontiers in physiology

authors： Carbonero F,Benefiel AC,Alizadeh-Ghamsari AH,Gaskins HR

更新日期：2012-11-28 00:00:00

abstract：:Chronic kidney disease (CKD) is a significant worldwide healthcare problem. Regardless of the initial injury, renal fibrosis is the common final pathway leading to end stage renal disease. Although the underlying mechanisms are not fully defined, evidence indicates that besides inflammation, oxidative stress plays a c...

journal_title：Frontiers in physiology

authors： Lv W,Booz GW,Fan F,Wang Y,Roman RJ

更新日期：2018-02-16 00:00:00

abstract：:Obesity is characterized by an excessive increase in body mass, leading to endothelial damage that may favor the development of erectile dysfunction (ED). ED is defined as the inability to achieve or maintain a penile erection long enough to have a sexual intercourse. In this context, different ED models were develope...

journal_title：Frontiers in physiology

authors： de Souza ILL,Barros BC,de Oliveira GA,Queiroga FR,Toscano LT,Silva AS,Silva PM,Interaminense LFL,Cavalcante FA,da Silva BA

更新日期：2017-10-04 00:00:00

abstract：:Sensory receptors, including olfactory receptors (ORs), taste receptors (TRs), and opsins (Opns) have recently been found in a variety of non-sensory tissues where they have distinct physiological functions. As G protein-coupled receptors (GPCRs), these proteins can serve as important chemosensors by sensing and inter...

journal_title：Frontiers in physiology

authors： Kurtz R,Steinberg LG,Betcher M,Fowler D,Shepard BD

更新日期：2020-10-06 00:00:00

abstract：:Several Octopodidae species have a great potential for the diversification of worldwide aquaculture. Unfortunately, the lack of stress-related biomarkers in this taxon results an obstacle for its maintenance in conditions where animal welfare is of paramount relevance. In this study, we made a first approach to uncove...

journal_title：Frontiers in physiology

authors： Barragán-Méndez C,Sobrino I,Marín-Rincón A,Fernández-Boo S,Costas B,Mancera JM,Ruiz-Jarabo I

更新日期：2019-06-25 00:00:00