SARS-CoV-2 Mediated Endothelial Dysfunction: The Potential Role of Chronic Oxidative Stress.

abstract：BACKGROUND:In patients with arterial hypertension, increased blood pressure (BP) variability contributes to end organ damage independently from mean levels of arterial BP. Increased BP variability has been linked to alterations in autonomic function including sympathetic overdrive. We hypothesized that catheter-based r...

journal_title：Frontiers in physiology

authors： Zuern CS,Rizas KD,Eick C,Stoleriu C,Bunk L,Barthel P,Balletshofer B,Gawaz M,Bauer A

更新日期：2012-05-10 00:00:00

abstract：:The ubiquitin proteasome system (UPS) is a highly regulated mechanism of intracellular protein degradation and turnover. To evaluate the effect of crowding stress on the UPS in fish, grass carp (Ctenopharyngodon idellus) were randomly reared at low stocking density (LSD, 0.9 kg m-2) or high stocking density (HSD, 5.9 ...

journal_title：Frontiers in physiology

authors： Sun Y,Liang X,Chen J,Tang R,Li L,Li D

更新日期：2018-07-05 00:00:00

abstract：:Malignant hypertension develops in some cases of hypertension but not in others. We hypothesized that an impaired neovascularization and a reduced capillary supply characterizes the malignant course of experimental hypertension. Two-kidney, one-clip renovascular hypertension was induced in rats; controls (sham) were s...

journal_title：Frontiers in physiology

authors： Hartner A,Jagusch L,Cordasic N,Amann K,Veelken R,Jacobi J,Hilgers KF

更新日期：2016-08-30 00:00:00

abstract：:This study aims to present complex network models which analyze professional swimmers of 50-m freestyle Olympic competitions, comparing characteristics and variables that are considered performance determinants. This comparative research includes Olympic medalists' versus non-medalists' behavior. Using data from 40 at...

journal_title：Frontiers in physiology

authors： Pereira-Ferrero VH,Lewis TG,Ferrero LGP,Duarte LT

更新日期：2019-09-03 00:00:00

abstract：:Objective: Chronic hypoxia causes pulmonary vasoconstriction leading to pulmonary hypertension and right ventricular hypertrophy. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthesis; its level increases in hypoxia (HX) concomitantly with reduced activity of dimethylarginine dim...

journal_title：Frontiers in physiology

authors： Hannemann J,Glatzel A,Hillig J,Zummack J,Schumacher U,Lüneburg N,Harbaum L,Böger R

更新日期：2020-11-12 00:00:00

abstract：:Prescribing the proper resistance training (RT) program is critical to optimize skeletal muscle hypertrophy and strength. Periodization is a strategy that entails planned manipulations of training variables to maximize fitness adaptations while minimizing the risk of overtraining. Multiple meta-analyses have shown per...

journal_title：Frontiers in physiology

authors： Evans JW

更新日期：2019-01-23 00:00:00

abstract：:Being the central metabolic organ of vertebrates, the liver possesses the largest repertoire of metabolic enzymes among all tissues and organs. Almost all metabolic pathways are resident in the parenchymal cell, hepatocyte, but the pathway capacities may largely differ depending on the localization of hepatocytes with...

journal_title：Frontiers in physiology

authors： Berndt N,Holzhütter HG

更新日期：2018-12-12 00:00:00

abstract：:RASA3 is a Ras GTPase activating protein that plays a critical role in blood formation. The autosomal recessive mouse model scat (severe combined anemia and thrombocytopenia) carries a missense mutation in Rasa3. Homozygotes present with a phenotype characteristic of bone marrow failure that is accompanied by alternat...

journal_title：Frontiers in physiology

authors： Hartman ES,Brindley EC,Papoin J,Ciciotte SL,Zhao Y,Peters LL,Blanc L

更新日期：2018-06-05 00:00:00

abstract：:In insects, locomotion is the result of rhythm generating thoracic circuits and their modulation by sensory reflexes and by inputs from the two head ganglia, the cerebral and the gnathal ganglia (GNG), which act as higher order neuronal centers playing different functions in the initiation, goal-direction, and mainten...

journal_title：Frontiers in physiology

authors： Emanuel S,Kaiser M,Pflueger HJ,Libersat F

更新日期：2020-02-21 00:00:00

abstract：:Spodoptera exigua and S. litura are two sympatric species in China and many other countries. Both moths employ a multiple component sex pheromone blend, including a common component Z9,E12-14:OAc, and two specific components Z9-14:OH and Z11-16:OAc for S. exigua, and one specific component Z9,E11-14:OAc for S. litura....

journal_title：Frontiers in physiology

authors： Yan Q,Liu XL,Wang YL,Tang XQ,Shen ZJ,Dong SL,Deng JY

更新日期：2019-09-27 00:00:00

abstract：:The human brain is constantly active and even small limitations to cerebral blood flow (CBF) may be critical for preserving oxygen and substrate supply, e.g., during exercise and hypoxia. Exhaustive exercise evokes a competition for the supply of oxygenated blood between the brain and the working muscles, and inabilit...

journal_title：Frontiers in physiology

authors： Kim YS,van der Ster BJP,Brassard P,Secher NH,van Lieshout JJ

更新日期：2021-01-15 00:00:00

abstract：:Infants born premature are at increased risk for development of bronchopulmonary dysplasia (BPD), pulmonary hypertension (PH), and ultimately right ventricular (RV) dysfunction, which together carry a high risk of neonatal mortality. However, the role alveolar simplification and abnormal pulmonary microvascular develo...

journal_title：Frontiers in physiology

authors： Patel JR,Barton GP,Braun RK,Goss KN,Haraldsdottir K,Hopp A,Diffee G,Hacker TA,Moss RL,Eldridge MW

更新日期：2017-10-25 00:00:00

abstract：:Lactic acid and short chain fatty acids (SCFAs) produced by vaginal microbiota have reported antimicrobial and immune modulatory activities indicating their potential as biomarkers of disease and/or disease susceptibility. In asymptomatic women of reproductive-age the vaginal microbiota is comprised of lactic acid-pro...

journal_title：Frontiers in physiology

authors： Aldunate M,Srbinovski D,Hearps AC,Latham CF,Ramsland PA,Gugasyan R,Cone RA,Tachedjian G

更新日期：2015-06-02 00:00:00

abstract：:This paper introduces the use of low frequencies forced oscillation technique (FOT) in the presence of breathing signal. The hypothesis tested is to evaluate the sensitivity of FOT to various degrees of obstruction in COPD patients. The measurements were performed in the frequency range 0-2 Hz. The use of FOT to evalu...

journal_title：Frontiers in physiology

authors： Ghita M,Copot D,Ghita M,Derom E,Ionescu C

更新日期：2019-11-19 00:00:00

abstract：:Anatomical evidence in several species shows highly heterogeneous fat distribution in the atrial and ventricular myocardium. Atrial appendages have fat deposits, and more so on the posterior left atrium. Although such fat distributions are considered normal, fatty infiltration is regarded arrhythmogenic, and various c...

journal_title：Frontiers in physiology

authors： Anumonwo JMB,Herron T

更新日期：2018-01-22 00:00:00

abstract：Introduction:Hypothermia has notable effects on platelets, platelet function, fibrinogen, and coagulation factors. Common laboratory techniques cannot identify those effects, because blood samples are usually warmed to 37°C before analysis and do not fully reflect the in vivo situation. Multiple aspects of the pathophy...

journal_title：Frontiers in physiology

authors： Wallner B,Schenk B,Hermann M,Paal P,Falk M,Strapazzon G,Martini WZ,Brugger H,Fries D

更新日期：2020-07-14 00:00:00

abstract：:The physiological mechanisms related to cardio-vascular (CV), cardio-pulmonary (CP), and vasculo-pulmonary (VP) regulation may be probed through multivariate time series analysis tools. This study applied an information domain approach for the evaluation of non-linear causality to the beat-to-beat variability series o...

journal_title：Frontiers in physiology

authors： Faes L,Nollo G,Porta A

更新日期：2011-11-07 00:00:00

abstract：:Glucose metabolism is a biologically important metabolic process. Glycogen synthase kinase (GSK-3) is a key enzyme located in the middle of the sugar metabolism pathway that can regulate the energy metabolism process in the body through insulin signaling. This paper mainly explores the regulatory effect of glycogen sy...

journal_title：Frontiers in physiology

authors： Ding YJ,Li GY,Xu CD,Wu Y,Zhou ZS,Wang SG,Li C

更新日期：2020-11-25 00:00:00

abstract：:Lineage fate decisions of hematopoietic cells depend on intrinsic factors and extrinsic signals provided by the bone marrow microenvironment, where they reside. Abnormalities in composition and function of hematopoietic niches have been proposed as key contributors of acute lymphoblastic leukemia (ALL) progression. Ou...

journal_title：Frontiers in physiology

authors： Enciso J,Mayani H,Mendoza L,Pelayo R

更新日期：2016-08-19 00:00:00

abstract：:Previous studies assessing effect of ischemia on ventricular repolarization are mostly directed toward patients with coronary artery disease (CAD); however, similar reports on cardiac syndrome X (CSX) are scarce. Whether microvascular dysfunction of CSX and ischemia induced by CAD produce comparable effect on ventricu...

journal_title：Frontiers in physiology

authors： Lutfi MF

更新日期：2016-09-21 00:00:00

abstract：:Pulpitis in primary teeth, a condition caused by presence of bacteria, is highly prevalent worldwide. The use of biocompatibility materials with anti-inflammatory, anti-bacterial, and regenerative properties is critical for prognosis of this endodontic disease. This study aimed to identify expression of human β defens...

journal_title：Frontiers in physiology

authors： Zhai Y,Wang Y,Rao N,Li J,Li X,Fang T,Zhao Y,Ge L

更新日期：2019-10-22 00:00:00

abstract：:Obesity is a worldwide epidemic disease that induces important structural and functional changes to the heart and predisposes a patient to devastating cardiac complications. Sirtuin1 (SIRT1) has been found to have roles in regulating cardiac function, but whether it can help in cardioprotection is not clear. The aim o...

journal_title：Frontiers in physiology

authors： Favero G,Franco C,Stacchiotti A,Rodella LF,Rezzani R

更新日期：2020-03-11 00:00:00

abstract：BACKGROUND:During caesarean section spinal anesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine. Phenylephrine is however reported to reduce the near infrared spectroscopy-determined frontal lobe oxygenation (ScO2) but whether that is the case for patients expo...

journal_title：Frontiers in physiology

authors： Foss VT,Christensen R,Rokamp KZ,Nissen P,Secher NH,Nielsen HB

更新日期：2014-03-03 00:00:00

abstract：:RNAi is applied as a new and safe method for pest control in agriculture but efficiency and specificity of delivery of dsRNA trigger remains a critical issue. Various agents have been proposed to augment dsRNA delivery, such as engineered micro-organisms and synthetic nanoparticles, but the use of viruses has received...

journal_title：Frontiers in physiology

authors： Kolliopoulou A,Taning CNT,Smagghe G,Swevers L

更新日期：2017-06-14 00:00:00

abstract：:Reticuloendothelial macrophages engulf ∼0.2 trillion senescent erythrocytes daily in a process called erythrophagocytosis (EP). This critical mechanism preserves systemic heme-iron homeostasis by regulating red blood cell (RBC) catabolism and iron recycling. Although extensive work has demonstrated the various effects...

journal_title：Frontiers in physiology

authors： Catala A,Youssef LA,Reisz JA,Dzieciatkowska M,Powers NE,Marchetti C,Karafin M,Zimring JC,Hudson KE,Hansen KC,Spitalnik SL,D'Alessandro A

更新日期：2020-04-30 00:00:00

abstract：:Exploration of non-coding genome has recently uncovered a growing list of formerly unknown regulatory long non-coding RNAs (lncRNAs) with important functions in stem cell pluripotency, development and homeostasis of several tissues. Although thousands of lncRNAs are expressed in mammalian brain in a highly patterned m...

journal_title：Frontiers in physiology

authors： Antoniou D,Stergiopoulos A,Politis PK

更新日期：2014-04-22 00:00:00

abstract：Background:Nav1.5 cardiac Na+ channel mutations can cause arrhythmogenic syndromes. Some of these mutations exert a dominant negative effect on wild-type channels. Recent studies showed that Na+ channels can dimerize, allowing coupled gating. This leads to the hypothesis that allosteric interactions between Na+ channel...

journal_title：Frontiers in physiology

authors： Hichri E,Selimi Z,Kucera JP

更新日期：2020-11-05 00:00:00

abstract：:Regulation of cardiac physiology is well known to occur through the action of kinases that reversibly phosphorylate ion channels, calcium handling machinery, and signaling effectors. However, it is becoming increasingly apparent that palmitoylation or S-acylation, the post-translational modification of cysteines with ...

journal_title：Frontiers in physiology

authors： Essandoh K,Philippe JM,Jenkins PM,Brody MJ

更新日期：2020-02-19 00:00:00

abstract：:Aim: The hemodynamic response to mouse systemic anaphylaxis is characterized by an initial hypertension followed by sustained hypotension. However, the defense mechanisms of the sympathetic nervous system against this circulatory disturbance is not known. Here, we investigated the renal sympathetic nerve activity (RSN...

journal_title：Frontiers in physiology

authors： Zhang T,Tanida M,Uchida K,Suzuki Y,Yang W,Kuda Y,Kurata Y,Tominaga M,Shibamoto T

更新日期：2017-09-07 00:00:00

abstract：Background:The aim of presented cross-sectional study was to determine the association of different types of physical activity (PA) with metabolic control in people with type 1 diabetes. Materials and Methods:A total of 109 adult subjects with type 1 diabetes were asked to complete the non-exercise activity thermogene...

journal_title：Frontiers in physiology

authors： Štotl I,Kambič T,Hadžić V,Zdolšek A

更新日期：2019-09-24 00:00:00