Beluga (Delphinapterus leucas) granulocytes and monocytes display variable responses to in vitro pressure exposures.

abstract：:RNAi is applied as a new and safe method for pest control in agriculture but efficiency and specificity of delivery of dsRNA trigger remains a critical issue. Various agents have been proposed to augment dsRNA delivery, such as engineered micro-organisms and synthetic nanoparticles, but the use of viruses has received...

journal_title：Frontiers in physiology

authors： Kolliopoulou A,Taning CNT,Smagghe G,Swevers L

更新日期：2017-06-14 00:00:00

abstract：:The epidemics of obesity and diabetes mellitus are associated with an increased incidence of both atrial fibrillation (AF), the most common sustained arrhythmia in adults, and sudden cardiac death (SCD). Obesity and DM are known to have adverse effects on cardiac structure and function. The pathologic mechanisms are t...

journal_title：Frontiers in physiology

authors： Homan EA,Reyes MV,Hickey KT,Morrow JP

更新日期：2019-01-07 00:00:00

abstract：:Eccentric loading is an effective stimulus for muscle hypertrophy and strength gains, however, the effect of lengthening velocity is under debate. The purpose of the current study was to investigate the influence of muscle lengthening velocity during eccentric training on muscle hypertrophy and strength gains at a giv...

journal_title：Frontiers in physiology

authors： Marzilger R,Bohm S,Mersmann F,Arampatzis A

更新日期：2019-07-31 00:00:00

abstract：:Background: It is known that the respiration-modulated photoplethysmographic (PPG) signals could be used to derive respiratory frequency (RF) and that PPG signals could be measured from different body sites. However, the accuracy of RF derived from PPG signals of different body sites has not been comprehensively inves...

journal_title：Frontiers in physiology

authors： Hartmann V,Liu H,Chen F,Hong W,Hughes S,Zheng D

更新日期：2019-06-18 00:00:00

abstract：:Temperature is an important abiotic factor that drives the evolution of ectotherms owing to its pervasive effects at all levels of organization. Although a species' thermal tolerance is environmentally driven within a spatial cline, it may be constrained over time due to differential phylogenetic inheritance. At the l...

journal_title：Frontiers in physiology

authors： Faria SC,Bianchini A,Lauer MM,Zimbardi ALRL,Tapella F,Romero MC,McNamara JC

更新日期：2020-04-24 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) caused by SARS-CoV2 is associated with various comorbidities; cardiovascular diseases, hypertension, diabetes, liver, lung diseases, and neurological ailments. The majority of the dysfunctions mentioned above are often associated with endothelial deterioration, indicating that endot...

journal_title：Frontiers in physiology

authors： Jakhmola S,Indari O,Baral B,Kashyap D,Varshney N,Das A,Chatterjee S,Jha HC

更新日期：2020-08-04 00:00:00

abstract：:Trace conditioning is a form of associative learning that can be induced by presenting a conditioned stimulus (CS) and an unconditioned stimulus (US) following each other, but separated by a temporal gap. This gap distinguishes trace conditioning from classical delay conditioning, where the CS and US overlap. To bridg...

journal_title：Frontiers in physiology

authors： Dylla KV,Galili DS,Szyszka P,Lüdke A

更新日期：2013-08-23 00:00:00

abstract：:Claudin-1 is a tight junction transmembrane protein. Its localization in the maturation ameloblasts of rat incisors was examined by immunofluorescence microscopy. Distal junction area of ruffle-ended ameloblasts (RA) and the Golgi apparatus of a sub-population of smooth-ended ameloblasts (SA) and RAs stained positive ...

journal_title：Frontiers in physiology

authors： Nishikawa S,Abe M

更新日期：2010-11-16 00:00:00

abstract：:Background: The possibility of non-invasively assessing load-independent parameters characterizing cardiac function is of high clinical value. Typically, these parameters are assessed during resting conditions. However, for diagnostic purposes, the parameter behavior across a physiologically relevant range of heart ra...

journal_title：Frontiers in physiology

authors： Casas B,Viola F,Cedersund G,Bolger AF,Karlsson M,Carlhäll CJ,Ebbers T

更新日期：2018-10-30 00:00:00

abstract：:Large-conductance calcium-activated potassium (BK) channels are currently considered as vital players in a variety of renal physiological processes. In podocytes, BK channels become active in response to stimuli that increase local cytosolic Ca(2+), possibly secondary to activation of slit diaphragm TRPC6 channels by ...

journal_title：Frontiers in physiology

authors： Tao J,Lan Z,Wang Y,Hei H,Tian L,Pan W,Zhang X,Peng W

更新日期：2016-06-21 00:00:00

abstract：:Background: Dental aberrations have been mentioned in relation to non-surgical hypoparathyroidism (Ns-HypoPT) and pseudohypoparathyroidism (PHP). However, a systematic review of dental characteristics have not been performed. The present systematic review describes the dental findings in patients with Ns-HypoPT and PH...

journal_title：Frontiers in physiology

authors： Hejlesen J,Underbjerg L,Gjørup H,Bloch-Zupan A,Sikjaer T,Rejnmark L,Haubek D

更新日期：2018-06-19 00:00:00

abstract：:About 14% of veterans who suffer from Gulf war illness (GWI) complain of some form of gastrointestinal disorder but with no significant markers of clinical pathology. Our previous studies have shown that exposure to GW chemicals resulted in altered microbiome which was associated with damage associated molecular patte...

journal_title：Frontiers in physiology

authors： Kimono D,Sarkar S,Albadrani M,Seth R,Bose D,Mondal A,Li Y,Kar AN,Nagarkatti M,Nagarkatti P,Sullivan K,Janulewicz P,Lasley S,Horner R,Klimas N,Chatterjee S

更新日期：2019-10-14 00:00:00

abstract：:For early prevention of cardiovascular disease, early detection and risk factor insights are necessary. The autonomic balance reflects cardiovascular risk and can be measured by heart rate variability (HRV). Therefore, our purpose is to examine associations between HRV and the energy-related biomarkers leptin and adip...

journal_title：Frontiers in physiology

authors： Van De Wielle R,Michels N

更新日期：2017-07-12 00:00:00

abstract：:The fluid transport and mixing induced by beating cilia, present in the bronchial airways, are studied using a coupled lattice Boltzmann-Immersed Boundary solver. This solver allows the simulation of both single and multi-component fluid flows around moving solid boundaries. The cilia are modeled by a set of Lagrangia...

journal_title：Frontiers in physiology

authors： Chateau S,D'Ortona U,Poncet S,Favier J

更新日期：2018-03-06 00:00:00

abstract：:Today, in silico studies and trial simulations already complement experimental approaches in pharmaceutical R&D and have become indispensable tools for decision making and communication with regulatory agencies. While biology is multiscale by nature, project work, and software tools usually focus on isolated aspects o...

journal_title：Frontiers in physiology

authors： Eissing T,Kuepfer L,Becker C,Block M,Coboeken K,Gaub T,Goerlitz L,Jaeger J,Loosen R,Ludewig B,Meyer M,Niederalt C,Sevestre M,Siegmund HU,Solodenko J,Thelen K,Telle U,Weiss W,Wendl T,Willmann S,Lippert J

更新日期：2011-02-24 00:00:00

abstract：:The luminal endoplasmic reticulum (ER) protein of 29 kDa (ERp29) is a ubiquitously expressed cellular agent with multiple critical roles. ERp29 regulates the biosynthesis and trafficking of several transmembrane and secretory proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR), the epith...

journal_title：Frontiers in physiology

authors： Brecker M,Khakhina S,Schubert TJ,Thompson Z,Rubenstein RC

更新日期：2020-09-08 00:00:00

abstract：:Skeletal muscle is a main target of insulin action that plays a pivotal role in postprandial glucose disposal. Importantly, skeletal muscle insulin sensitivity relates inversely with pancreatic insulin secretion, which prompted the hypothesis of the existence of a skeletal muscle-pancreas crosstalk mediated through an...

journal_title：Frontiers in physiology

authors： Mizgier ML,Fernández-Verdejo R,Cherfan J,Pinget M,Bouzakri K,Galgani JE

更新日期：2019-08-08 00:00:00

abstract：:The rare opportunity to study a human fetus showing bilateral clefting of the lower lip along with other associated anomalies resembling those of the equally rare Pena-Shokeir phenotype prompts this report. The scarcity of reports on bilateral clefts of the lower lip has strengthened the conventional understanding or,...

journal_title：Frontiers in physiology

authors： Vastardis H,Spyropoulos MN,Burdi AR

更新日期：2012-08-24 00:00:00

abstract：:Muscle wasting in cancer cachexia can be alleviated by blocking activin receptor type 2 (ACVR2) ligands through changes in protein synthesis/degradation. These changes in cellular and protein metabolism may alter protein homeostasis. First, we elucidated the acute (1-2 days) and 2-week effects of blocking ACVR2 ligand...

journal_title：Frontiers in physiology

authors： Hentilä J,Nissinen TA,Korkmaz A,Lensu S,Silvennoinen M,Pasternack A,Ritvos O,Atalay M,Hulmi JJ

更新日期：2019-01-18 00:00:00

abstract：:To determine the level of hypoxia from which muscle activation (MA) is reduced during incremental exercise to exhaustion (IE), and the role played by PIO2 in this process, ten volunteers (21 ± 2 years) performed four IE in severe acute hypoxia (SAH) (PIO2 = 73 mmHg). Upon exhaustion, subjects were asked to continue ex...

journal_title：Frontiers in physiology

authors： Torres-Peralta R,Losa-Reyna J,Morales-Alamo D,González-Izal M,Pérez-Suárez I,Ponce-González JG,Izquierdo M,Calbet JA

更新日期：2016-08-17 00:00:00

abstract：:Significant progress has been made in the last decade in the development of optogenetic effectors and sensors that can be deployed to understand complex biological signaling in mammals at a molecular level, without disrupting the distributed, lineage specific signaling circuits that comprise nuanced physiological resp...

journal_title：Frontiers in physiology

authors： Shui B,Lee JC,Reining S,Lee FK,Kotlikoff MI

更新日期：2014-11-06 00:00:00

abstract：:Caveolae are membrane micro-domains enriched in cholesterol, sphingolipids and caveolins, which are transmembrane proteins with a hairpin-like structure. Caveolae participate in receptor-mediated trafficking of cell surface receptors and receptor-mediated signaling. Furthermore, caveolae participate in clathrin-indepe...

journal_title：Frontiers in physiology

authors： Navarro G,Borroto-Escuela DO,Fuxe K,Franco R

更新日期：2014-09-30 00:00:00

abstract：:An increase in calorie consumption is associated with the recent rise in obesity prevalence. However, our current understanding of the effects of nutrient excess on major metabolic pathways appears insufficient to develop safe and effective metabolic interventions to prevent obesity. Hence, we sought to identify syste...

journal_title：Frontiers in physiology

authors： Sansbury BE,Bhatnagar A,Hill BG

更新日期：2014-11-25 00:00:00

abstract：:In recent years, time-varying inhomogeneous point process models have been introduced for assessment of instantaneous heartbeat dynamics as well as specific cardiovascular control mechanisms and hemodynamics. Assessment of the model's statistics is established through the Wiener-Volterra theory and a multivariate auto...

journal_title：Frontiers in physiology

authors： Chen Z,Purdon PL,Brown EN,Barbieri R

更新日期：2012-02-01 00:00:00

abstract：:To fully unravel the ixodid ticks' role as vectors of viral pathogens, their susceptibility to new control measures, and their ability to develop acaricide resistance, acclimatization of ticks under laboratory conditions is greatly needed. However, the unique and complicated feeding behavior of these ticks compared to...

journal_title：Frontiers in physiology

authors： Talactac MR,Hernandez EP,Fujisaki K,Tanaka T

更新日期：2018-12-04 00:00:00

abstract：:Circadian rhythms are essential for health and regulate various physiological functions. These rhythms are regulated by a negative-feedback loop involving clock genes in the suprachiasmatic nucleus (SCN) and peripheral tissues. The rate of secretion of salivary substances, ions, and water follows a circadian rhythm, h...

journal_title：Frontiers in physiology

authors： Satou R,Sato M,Kimura M,Ishizuka Y,Tazaki M,Sugihara N,Shibukawa Y

更新日期：2017-05-23 00:00:00

abstract：:Liver cirrhosis (LC) is the final usual outcome of liver damage induced by various chronic liver diseases. Because of asymptomatic nature of LC, it is usually diagnosed at late and advanced stages, and patients are easy to miss the best timing for treatment. Thus, the early detection of LC is needed. In the prospectiv...

journal_title：Frontiers in physiology

authors： Yoo HJ,Jung KJ,Kim M,Kim M,Kang M,Jee SH,Choi Y,Lee JH

更新日期：2019-11-19 00:00:00

abstract：:Octopuses (Octopus vulgaris) are generally considered to possess extraordinary cognitive abilities including the ability to successfully perform in a serial reversal learning task. During reversal learning, an animal is presented with a discrimination problem and after reaching a learning criterion, the signs of the s...

journal_title：Frontiers in physiology

authors： Bublitz A,Weinhold SR,Strobel S,Dehnhardt G,Hanke FD

更新日期：2017-02-07 00:00:00

abstract：:Background: Understanding the microscopic dynamics of the beating heart has been challenging due to the technical nature of imaging with micrometer resolution while the heart moves. The development of multiphoton microscopy has made in vivo, cell-resolved measurements of calcium dynamics and vascular function possible...

journal_title：Frontiers in physiology

authors： Jones JS,Small DM,Nishimura N

更新日期：2018-07-31 00:00:00

abstract：:Spinal muscular atrophy (SMA), amyotrophic lateral sclerosis (ALS), and spinal-bulbar muscular atrophy (SBMA) are devastating diseases characterized by the degeneration of motor neurons. Although the molecular causes underlying these diseases differ, recent findings have highlighted the contribution of intrinsic skele...

journal_title：Frontiers in physiology

authors： Boyer JG,Ferrier A,Kothary R

更新日期：2013-12-18 00:00:00