Environmental Enrichment Modulates Drug Addiction and Binge-Like Consumption of Highly Rewarding Substances: A Role for Anxiety and Compulsivity Brain Systems?

abstract：:The relationship between stress and drug use is well demonstrated. Stress-induced by repeated social defeat (RSD) enhances the conditioned place preference (CPP) induced by cocaine in mice. The phenomenon of resilience understood as the ability of subjects to overcome the negative effects of stress is the focus of inc...

journal_title：Frontiers in behavioral neuroscience

authors： Calpe-López C,García-Pardo MP,Martínez-Caballero MA,Santos-Ortíz A,Aguilar MA

更新日期：2020-01-09 00:00:00

abstract：:Inbred Wistar Kyoto (WKY) rats express inhibited temperament, increased sensitivity to stress, and exaggerated expressions of avoidance. A long-standing observation for lever press escape/avoidance learning in rats is the duration of the warning signal (WS) determines whether avoidance is expressed over escape. Outbre...

journal_title：Frontiers in behavioral neuroscience

authors： Servatius RJ,Avcu P,Ko N,Jiao X,Beck KD,Minor TR,Pang KC

更新日期：2015-07-06 00:00:00

abstract：:An influential model suggests that dopamine signals the difference between predicted and experienced reward. In this way, dopamine can act as a learning signal that can shape behaviors to maximize rewards and avoid punishments. Dopamine is also thought to invigorate reward seeking behavior. Loss of dopamine signaling ...

journal_title：Frontiers in behavioral neuroscience

authors： Clark CA,Dagher A

更新日期：2014-05-30 00:00:00

abstract：:Testosterone reduces anxiety-like behaviors in rodents and increases exploration of anxiogenic parts of the environment. Effects of testosterone on innate defensive behaviors remain understudied. Here, we demonstrate that exogenous testosterone reduces aversion to cat odor in male mice. This is reflected as increased ...

journal_title：Frontiers in behavioral neuroscience

authors： Tong WH,Abdulai-Saiku S,Vyas A

更新日期：2019-02-26 00:00:00

abstract：:Nicotine use in adolescence is pervasive in the United States and, according to the Gateway Hypothesis, may lead to progression towards other addictive substances. Given the prevalence of nicotine and ethanol comorbidity, it is difficult to ascertain if nicotine is a gateway drug for ethanol. Our study investigated th...

journal_title：Frontiers in behavioral neuroscience

authors： Madayag AC,Czarnecki KS,Wangler LM,Robinson DL

更新日期：2017-08-17 00:00:00

abstract：:Animals must make constant decisions whether to respond to external sensory stimuli or not to respond. The activation of positive and/or negative reinforcers might bias the behavioral response towards approach or aversion. To analyze whether the activation of the octopaminergic neurotransmitter system can shift the de...

journal_title：Frontiers in behavioral neuroscience

authors： Claßen G,Scholz H

更新日期：2018-07-03 00:00:00

abstract：:The endocannabinoid (eCB) system possesses neuromodulatory functions by influencing the release of various neurotransmitters, including γ-aminobutyric acid (GABA) and glutamate. A functional interaction between eCBs and the serotonergic system has already been suggested. Previously, we showed that cannabinoid type-1 (...

journal_title：Frontiers in behavioral neuroscience

authors： Häring M,Enk V,Aparisi Rey A,Loch S,Ruiz de Azua I,Weber T,Bartsch D,Monory K,Lutz B

更新日期：2015-09-03 00:00:00

abstract：:"Schizotypy" is a latent organization of personality related to the genetic risk for schizophrenia. Some evidence suggests that schizophrenia and schizotypy share some biological features, including a link to dopaminergic D2 receptor signaling. A polymorphism in the D2 gene (DRD2 rs1076560, guanine > thymine (G > T)) ...

journal_title：Frontiers in behavioral neuroscience

authors： Taurisano P,Romano R,Mancini M,Giorgio AD,Antonucci LA,Fazio L,Rampino A,Quarto T,Gelao B,Porcelli A,Papazacharias A,Ursini G,Caforio G,Masellis R,Niccoli-Asabella A,Todarello O,Popolizio T,Rubini G,Blasi G,Bertolin

更新日期：2014-07-09 00:00:00

abstract：:Postpartum depression is a complex illness that often occurs in genetically predisposed individuals. Closely related inbred rat strains are a great resource to identify novel causative genes and mechanisms underlying complex traits such as postpartum behavior. We report differences in these behaviors between the inbre...

journal_title：Frontiers in behavioral neuroscience

authors： Luo W,Lim PH,Wert SL,Gacek SA,Chen H,Redei EE

更新日期：2020-10-22 00:00:00

abstract：:The dopaminergic system is known to be involved in working memory processed by several brain regions like prefrontal cortex (PFC), hippocampus, striatum. In an earlier study we could show that Levodopa but not Modafinil enhanced working memory in a T-maze only during the early phase of training (day 3), whereas the la...

journal_title：Frontiers in behavioral neuroscience

authors： Bezu M,Maliković J,Kristofova M,Engidawork E,Höger H,Lubec G,Korz V

更新日期：2017-10-13 00:00:00

abstract：:Background: Women are twice as likely as men to develop major depression. The brain mechanisms underlying this sex disparity are not clear. Disruption of the glutamate-glutamine cycle has been implicated in psychiatric disturbances. This study identifies sex-based impairments in the glutamate-glutamine cycle involving...

journal_title：Frontiers in behavioral neuroscience

authors： Rappeneau V,Blaker A,Petro JR,Yamamoto BK,Shimamoto A

更新日期：2016-12-06 00:00:00

abstract：:MANY FLYING INSECTS EXHIBIT AN ACTIVE FLIGHT AND GAZE STRATEGY: purely translational flight segments alternate with quick turns called saccades. To generate such a saccadic flight pattern, the animals decide the timing, direction, and amplitude of the next saccade during the previous translatory intersaccadic interval...

journal_title：Frontiers in behavioral neuroscience

authors： Lindemann JP,Egelhaaf M

更新日期：2013-01-11 00:00:00

abstract：:L-Kynurenine (L-KYN) is a central metabolite of tryptophan degradation through the kynurenine pathway (KP). The systemic administration of L-KYN sulfate (L-KYNs) leads to a rapid elevation of the neuroactive KP metabolite kynurenic acid (KYNA). An elevated level of KYNA may have multiple effects on the synaptic transm...

journal_title：Frontiers in behavioral neuroscience

authors： Varga D,Herédi J,Kánvási Z,Ruszka M,Kis Z,Ono E,Iwamori N,Iwamori T,Takakuwa H,Vécsei L,Toldi J,Gellért L

更新日期：2015-06-16 00:00:00

abstract：:Several lines of evidence suggest the involvement of prefrontal cortex in time interval estimation. The underlying neural processes are poorly understood, however, in part because of the paucity of physiological studies. The goal of this study was to establish an interval timing task for physiological recordings in ra...

journal_title：Frontiers in behavioral neuroscience

authors： Kim J,Jung AH,Byun J,Jo S,Jung MW

更新日期：2009-11-03 00:00:00

abstract：:Magnetoreception can play a substantial role in long distance navigation by animals. I hypothesize that locomotion guided by a magnetic compass sense could also play a role in short distance navigation. Animals identify mates, prey, or other short distance navigational goals using different sensory modalities (olfacti...

journal_title：Frontiers in behavioral neuroscience

authors： Wyeth RC

更新日期：2010-07-30 00:00:00

abstract：:Much research has recognized the general importance of maternal behavior in the early development and programing of the mammalian offspring's brain. Exclusive breastfeeding (EBF) duration, the amount of time in which breastfed meals are the only source of sustenance, plays a prominent role in promoting healthy brain a...

journal_title：Frontiers in behavioral neuroscience

authors： Krol KM,Rajhans P,Missana M,Grossmann T

更新日期：2015-01-22 00:00:00

abstract：:Many epidemiological studies have described an adolescent-related psychiatric illness and sensorimotor deficits after Glyphosate based herbicide (GBH) exposure. GBH exposure in animal models of various ages suggests that it may be neurotoxic and could impact brain development and subsequently, behavior in adulthood. H...

journal_title：Frontiers in behavioral neuroscience

authors： Ait Bali Y,Ba-Mhamed S,Bennis M

更新日期：2017-08-08 00:00:00

abstract：:Space and shape are distinct perceptual categories. In language, perceptual information can also be used to describe abstract semantic concepts like a "rising income" (space) or a "square personality" (shape). Despite being inherently concrete, co-speech gestures depicting space and shape can accompany concrete or abs...

journal_title：Frontiers in behavioral neuroscience

authors： Nagels A,Chatterjee A,Kircher T,Straube B

更新日期：2013-12-18 00:00:00

abstract：:The developing brain is vulnerable to social defeat during the juvenile period. As complements of human studies, animal models of social defeat provide a straightforward approach to investigating the functional and neurobiological consequences of social defeats. Taking advantage of agonist behavior and social defeat i...

journal_title：Frontiers in behavioral neuroscience

authors： Yu WC,Liu CY,Lai WS

更新日期：2016-06-10 00:00:00

abstract：:Context conditioning is characterized by unpredictable threat and its generalization may constitute risk factors for panic disorder (PD). Therefore, we examined differences between individuals with panic attacks (PA; N = 21) and healthy controls (HC, N = 22) in contextual learning and context generalization using a vi...

journal_title：Frontiers in behavioral neuroscience

authors： Neueder D,Andreatta M,Pauli P

更新日期：2019-07-17 00:00:00

abstract：:The tendency to make unhealthy choices is hypothesized to be related to an individual's temporal discount rate, the theoretical rate at which they devalue delayed rewards. Furthermore, a particular form of temporal discounting, hyperbolic discounting, has been proposed to explain why unhealthy behavior can occur despi...

journal_title：Frontiers in behavioral neuroscience

authors： Story GW,Vlaev I,Seymour B,Darzi A,Dolan RJ

更新日期：2014-03-12 00:00:00

abstract：:We previously developed rat experimental models based on the conditioned place preference (CPP) paradigm in which only four 15-min episodes of dyadic social interaction with a sex- and weight-matched male Sprague Dawley (SD) rat (1) reversed CPP from cocaine to social interaction despite continuing cocaine training, a...

journal_title：Frontiers in behavioral neuroscience

authors： Kummer KK,Hofhansel L,Barwitz CM,Schardl A,Prast JM,Salti A,El Rawas R,Zernig G

更新日期：2014-10-17 00:00:00

abstract：:We performed whole-cell recordings from basal forebrain (BF) cholinergic neurons in transgenic mice expressing enhanced green fluorescent protein (eGFP) under the control of the choline acetyltransferase promoter. BF cholinergic neurons can be differentiated into two electrophysiologically identifiable subtypes: early...

journal_title：Frontiers in behavioral neuroscience

authors： Unal CT,Golowasch JP,Zaborszky L

更新日期：2012-05-08 00:00:00

abstract：:Reactive and proactive controls of actions are cognitive abilities that allow one to deal with a continuously changing environment by adjusting already programmed actions. They also set forthcoming actions by evaluating the outcome of the previous ones. Earlier studies highlighted sex-related differences in the strate...

journal_title：Frontiers in behavioral neuroscience

authors： Mione V,Canterini S,Brunamonti E,Pani P,Donno F,Fiorenza MT,Ferraina S

更新日期：2015-05-19 00:00:00

abstract：:In the present review, we provide evidence indicating that although post traumatic stress disorder (PTSD) and substance use disorder (SUD) are two distinct pathologies with very different impacts on people affected by these chronic illnesses, they share numerous common characteristics, present high rates of co-morbidi...

journal_title：Frontiers in behavioral neuroscience

authors： Gisquet-Verrier P,Le Dorze C

更新日期：2019-02-13 00:00:00

abstract：:Over the past 25 years, visual processing has been discussed in the context of the dual stream hypothesis consisting of a ventral ("what") and a dorsal ("where") visual information processing pathway. Patients with brain damage of the ventral pathway typically present with signs of visual agnosia, the inability to ide...

journal_title：Frontiers in behavioral neuroscience

authors： Huberle E,Rupek P,Lappe M,Karnath HO

更新日期：2012-08-28 00:00:00

abstract：:Marijuana is a prevalent illicit substance used by adolescents, and several studies have indicated that adolescent use can lead to long-term cognitive deficits including problems with attention and memory. However, preclinical animal studies that observe cognitive deficits after cannabinoid exposure during adolescence...

journal_title：Frontiers in behavioral neuroscience

authors： Kirschmann EK,McCalley DM,Edwards CM,Torregrossa MM

更新日期：2017-07-21 00:00:00

abstract：:Animals rely on sensory feedback from their environment to guide locomotion. For instance, visually guided animals use patterns of optic flow to control their velocity and to estimate their distance to objects (e.g., Srinivasan et al., 1991, 1996). In this study, we investigated how acoustic information guides locomot...

journal_title：Frontiers in behavioral neuroscience

authors： Warnecke M,Lee WJ,Krishnan A,Moss CF

更新日期：2016-04-25 00:00:00

abstract：:One function of glucocorticoids is to restore homeostasis after an acute stress response by providing negative feedback to stress circuits in the brain. Loss of this negative feedback leads to elevated physiological stress and may contribute to depression, anxiety, and post-traumatic stress disorder. We investigated t...

journal_title：Frontiers in behavioral neuroscience

authors： Griffiths BB,Schoonheim PJ,Ziv L,Voelker L,Baier H,Gahtan E

更新日期：2012-10-11 00:00:00

abstract：:Social interactions are critically important for survival and impact overall-health, but also impose costs on animals, such as exposure to contagious agents. The immune system can play a critical role in modulating social behavior when animals are sick, as has been demonstrated within the context of "sickness behavior...

journal_title：Frontiers in behavioral neuroscience

authors： Lopes PC,Carlitz EHD,Kindel M,König B

更新日期：2020-02-05 00:00:00