Functional characterization of dopamine transporter in vivo using Drosophila melanogaster behavioral assays.

abstract：:An imbalance in the neural motivational system may underlie Social Anxiety Disorder (SAD). This study examines social reward and punishment anticipation in SAD, predicting a valence-specific effect: increased striatal activity for punishment avoidance compared to obtaining a reward. Individuals with SAD (n = 20) and a...

journal_title：Frontiers in behavioral neuroscience

authors： Cremers HR,Veer IM,Spinhoven P,Rombouts SA,Roelofs K

更新日期：2015-01-05 00:00:00

abstract：:Animals must make constant decisions whether to respond to external sensory stimuli or not to respond. The activation of positive and/or negative reinforcers might bias the behavioral response towards approach or aversion. To analyze whether the activation of the octopaminergic neurotransmitter system can shift the de...

journal_title：Frontiers in behavioral neuroscience

authors： Claßen G,Scholz H

更新日期：2018-07-03 00:00:00

abstract：:Although gene-environment interactions are known to significantly influence psychopathology-related disease states, only few animal models cover both the genetic background and environmental manipulations. Therefore, we have taken advantage of the bidirectionally inbred high (HAB) and low (LAB) anxiety-related behavio...

journal_title：Frontiers in behavioral neuroscience

authors： Chekmareva NY,Sotnikov SV,Diepold RP,Naik RR,Landgraf R,Czibere L

更新日期：2014-03-18 00:00:00

abstract：:The Supplementary Eye Field (SEF) and the Frontal Eye Field (FEF) have been described as participating in gaze shift control. Recent evidence suggests, however, that other areas of the dorsomedial prefrontal cortex also influence gaze shift. Herein, we have investigated electrically evoked ear- and eye movements from ...

journal_title：Frontiers in behavioral neuroscience

authors： Lanzilotto M,Perciavalle V,Lucchetti C

更新日期：2015-01-30 00:00:00

abstract：:Maternal exposure to infection occurring mid-gestation produces a three-fold increase in the risk of schizophrenia in the offspring. The critical initiating factor appears to be the maternal immune activation (MIA) that follows infection. This process can be induced in rodents by exposure of pregnant dams to the viral...

journal_title：Frontiers in behavioral neuroscience

authors： Dickerson DD,Bilkey DK

更新日期：2013-12-27 00:00:00

abstract：:Early life adversity increases anxiety in adult rodents and primates, and increases the risk for developing post-traumatic disorder (PTSD) in humans. We hypothesized that early adversity impairs the use of learning signals -negative, aversive prediction errors-to reduce fear in uncertainty. To test this hypothesis, we...

journal_title：Frontiers in behavioral neuroscience

authors： Wright KM,DiLeo A,McDannald MA

更新日期：2015-08-27 00:00:00

abstract：:During active tactile exploration with their whiskers (vibrissae), rodents can rapidly orient to an object even though there are very few proprioceptors in the whisker muscles. Thus a long-standing question in the study of the vibrissal system is how the rat can localize an object in head-centered coordinates without ...

journal_title：Frontiers in behavioral neuroscience

authors： Yang AE,Hartmann MJ

更新日期：2016-07-19 00:00:00

abstract：:Visual-to-auditory sensory substitution is used to convey visual information through audition, and it was initially created to compensate for blindness; it consists of software converting the visual images captured by a video-camera into the equivalent auditory images, or "soundscapes". Here, it was used by blindfolde...

journal_title：Frontiers in behavioral neuroscience

authors： Pasqualotto A,Esenkaya T

更新日期：2016-04-21 00:00:00

abstract：:Extensive evidence indicates that glucocorticoid hormones act in a variety of brain regions to enhance the consolidation of memory of emotionally motivated training experiences. We previously reported that corticosterone, the major glucocorticoid in the rat, administered into the dorsal striatum immediately after inhi...

journal_title：Frontiers in behavioral neuroscience

authors： Sánchez-Resendis O,Medina AC,Serafín N,Prado-Alcalá RA,Roozendaal B,Quirarte GL

更新日期：2012-06-22 00:00:00

abstract：:The avoidance response is present in pathological anxiety and interferes with normal daily functions. The aim of this article is to shed light on performance markers of active avoidance (AA) using two different rat strains, Sprague-Dawley (SD) and Wistar. Specifically, good and poor performers were evaluated regarding...

journal_title：Frontiers in behavioral neuroscience

authors： de Oliveira CC,Gouveia FV,de Castro MC,Kuroki MA,Dos Santos LC,Fonoff ET,Teixeira MJ,Otoch JP,Martinez RC

更新日期：2016-08-24 00:00:00

abstract：:Pyriproxyfen is one of the most used larvicides and insecticides; it acts as an analog of juvenile insect hormone (a growth regulator). It is highly toxic during all stages of mosquito development, suppresses metamorphosis, and interferes in insect reproduction and proliferation. Pyriproxyfen and its main metabolite h...

journal_title：Frontiers in behavioral neuroscience

authors： Gusso D,Reolon GK,Gonzalez JB,Altenhofen S,Kist LW,Bogo MR,Bonan CD

更新日期：2020-06-17 00:00:00

abstract：:Extensive research on humans has improved our understanding of how the brain integrates information from our different senses, and has begun to uncover the brain regions and large-scale neural activity that contributes to an observer's ability to perceive the relative timing of auditory and visual stimuli. In the pres...

journal_title：Frontiers in behavioral neuroscience

authors： Schormans AL,Scott KE,Vo AM,Tyker A,Typlt M,Stolzberg D,Allman BL

更新日期：2017-01-10 00:00:00

abstract：:Although habituation is possibly the simplest form of learning, we still do not fully understand the neurobiological basis of habituation in any organism. To advance the goal of a comprehensive understanding of habituation, we have studied long-term habituation (LTH) of the gill-withdrawal reflex (GWR) in the marine s...

journal_title：Frontiers in behavioral neuroscience

authors： Esdin J,Pearce K,Glanzman DL

更新日期：2010-11-29 00:00:00

abstract：:Recent research suggests that conceptual or emotional factors could influence the perceptual processing of stimuli. In this article, we aimed to evaluate the effect of social information (positive, negative, or no information related to the character of the target) on subjective (perceived and felt valence and arousal...

journal_title：Frontiers in behavioral neuroscience

authors： Mermillod M,Grynberg D,Pio-Lopez L,Rychlowska M,Beffara B,Harquel S,Vermeulen N,Niedenthal PM,Dutheil F,Droit-Volet S

更新日期：2018-01-09 00:00:00

abstract：:Problematic alcohol drinking and alcohol dependence are an increasing health problem worldwide. Alcohol abuse is responsible for approximately 5% of the total deaths in the world, but addictive consumption of it has a substantial impact on neurological and memory disabilities throughout the population. One of the bett...

journal_title：Frontiers in behavioral neuroscience

authors： Mira RG,Lira M,Tapia-Rojas C,Rebolledo DL,Quintanilla RA,Cerpa W

更新日期：2020-01-24 00:00:00

abstract：:Testosterone reduces anxiety-like behaviors in rodents and increases exploration of anxiogenic parts of the environment. Effects of testosterone on innate defensive behaviors remain understudied. Here, we demonstrate that exogenous testosterone reduces aversion to cat odor in male mice. This is reflected as increased ...

journal_title：Frontiers in behavioral neuroscience

authors： Tong WH,Abdulai-Saiku S,Vyas A

更新日期：2019-02-26 00:00:00

abstract：:First-line treatment of major depression includes administration of a selective serotonin reuptake inhibitor (SSRI), yet studies suggest that remission rates following two trials of an SSRI are <50%. The authors examine the putative biological substrates underlying "treatment resistant depression (TRD)" with the goal ...

journal_title：Frontiers in behavioral neuroscience

authors： Coplan JD,Gopinath S,Abdallah CG,Berry BR

更新日期：2014-05-20 00:00:00

abstract：:Distinct manifestations of sexual behavior are conceived as separate phenotypes. Each sexual phenotype is assumed to be associated with a characteristic brain. These notions have justified the phenotyping of heterosexual copulator males based upon their ejaculation's latencies (EL) or frequencies (i.e., cumulative eja...

journal_title：Frontiers in behavioral neuroscience

authors： Trejo-Sánchez I,Pérez-Monter C,Huerta-Pacheco S,Gutiérrez-Ospina G

更新日期：2020-06-26 00:00:00

abstract：:The ability to accurately integrate or bind stimuli from more than one sensory modality is highly dependent on the features of the stimuli, such as their intensity and relative timing. Previous studies have demonstrated that the ability to perceptually bind stimuli is impaired in various clinical conditions such as au...

journal_title：Frontiers in behavioral neuroscience

authors： Schormans AL,Allman BL

更新日期：2018-10-31 00:00:00

abstract：:Affective tactile stimulation plays a key role in the maturation of neural circuits, but the development of brain mechanisms processing touch is poorly understood. We therefore used functional magnetic resonance imaging (fMRI) to study brain responses to soft brush stroking of both glabrous (palm) and hairy (forearm) ...

journal_title：Frontiers in behavioral neuroscience

authors： Björnsdotter M,Gordon I,Pelphrey KA,Olausson H,Kaiser MD

更新日期：2014-02-04 00:00:00

abstract：:Inbred Wistar Kyoto (WKY) rats express inhibited temperament, increased sensitivity to stress, and exaggerated expressions of avoidance. A long-standing observation for lever press escape/avoidance learning in rats is the duration of the warning signal (WS) determines whether avoidance is expressed over escape. Outbre...

journal_title：Frontiers in behavioral neuroscience

authors： Servatius RJ,Avcu P,Ko N,Jiao X,Beck KD,Minor TR,Pang KC

更新日期：2015-07-06 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a trophic factor regulating cell survival and synaptic plasticity. Recent findings indicate that BDNF could be a potential regulatory factor for cognitive functioning in normal and/or neuropathological conditions. With regard to neurological disorders, recent data suggest th...

journal_title：Frontiers in behavioral neuroscience

authors： Costa A,Peppe A,Carlesimo GA,Zabberoni S,Scalici F,Caltagirone C,Angelucci F

更新日期：2015-09-15 00:00:00

abstract：:In a conventional view of motor control, the human brain might employ an optimization principle that leads a stereotypical motor behavior which we observe as an averaged behavioral data over subjects. In this scenario, the inter-individual motor variability is considered as an observation noise. Here, we challenged th...

journal_title：Frontiers in behavioral neuroscience

authors： Kita K,Osu R,Hosoda C,Honda M,Hanakawa T,Izawa J

更新日期：2019-03-06 00:00:00

abstract：:The gradual accumulation of sensory evidence is a crucial component of perceptual decision making, but its neural mechanisms are still poorly understood. Given the wide availability of genetic and optical tools for mice, they can be useful model organisms for the study of these phenomena; however, behavioral tools are...

journal_title：Frontiers in behavioral neuroscience

authors： Pinto L,Koay SA,Engelhard B,Yoon AM,Deverett B,Thiberge SY,Witten IB,Tank DW,Brody CD

更新日期：2018-03-06 00:00:00

abstract：:Cross-situational word learning is based on the notion that a learner can determine the referent of a word by finding something in common across many observed uses of that word. Here we propose an adaptive learning algorithm that contains a parameter that controls the strength of the reinforcement applied to associati...

journal_title：Frontiers in behavioral neuroscience

authors： Tilles PF,Fontanari JF

更新日期：2013-11-19 00:00:00

abstract：:When stepping onto a stopped escalator, we often perceive an "odd sensation" that is never felt when stepping onto stairs. The sight of an escalator provides a strong contextual cue that, in expectation of the backward acceleration when stepping on, triggers an anticipatory forward postural adjustment driven by a habi...

journal_title：Frontiers in behavioral neuroscience

authors： Gomi H,Sakurada T,Fukui T

更新日期：2014-03-20 00:00:00

abstract：:Moral decision making involves affective and cognitive functions like emotional empathy, reasoning and cognitive empathy/theory of mind (ToM), which are discussed to be subject to age-related alterations. Additionally, sex differences in moral decision making have been reported. However, age-related changes in moral d...

journal_title：Frontiers in behavioral neuroscience

authors： Rosen JB,Brand M,Kalbe E

更新日期：2016-04-12 00:00:00

abstract：:Little is known regarding inter-individual differences in attentional biases for pain-related information; more knowledge is crucial, since these biases have been associated with differences in pain processing as well as in predicting the risk of postoperative pain. The present study investigated EEG correlates of att...

journal_title：Frontiers in behavioral neuroscience

authors： van Heck CH,Oosterman JM,de Kleijn KMA,Jongsma MLA,van Rijn CM

更新日期：2017-05-12 00:00:00

abstract：:The startle response is an unconditional reflex, characterized by the rapid contraction of facial and skeletal muscles, to a sudden and intense startling stimulus. It is an especially useful tool in translational research for its consistency across species, simple neural circuitry, and sensitivity to a variety of expe...

journal_title：Frontiers in behavioral neuroscience

authors： Pantoni MM,Herrera GM,Van Alstyne KR,Anagnostaras SG

更新日期：2020-06-03 00:00:00

abstract：:The notion that epigenetics may play an important role in the establishment and maintenance of sex differences in the brain has garnered great enthusiasm but the reality in terms of actual advances has been slow. Two general approaches include the comparison of a particular epigenetic mark in males vs. females and the...

journal_title：Frontiers in behavioral neuroscience

authors： McCarthy MM,Nugent BM

更新日期：2015-08-21 00:00:00