Abstract:
:Cryptochromes (CRYs) are a class of flavoproteins that sense blue light. In animals, CRYs are expressed in the eyes and in the clock neurons that control sleep/wake cycles and are implied in the generation and/or entrainment of circadian rhythmicity. Moreover, CRYs are sensing magnetic fields in insects as well as in humans. Here, we show that in the fruit fly Drosophila melanogaster CRY plays a light-independent role as "assembling" protein in the rhabdomeres of the compound eyes. CRY interacts with actin and appears to increase light sensitivity of the eyes by keeping the "signalplex" of the phototransduction cascade close to the membrane. By this way, CRY also enhances light-responses of the circadian clock.
journal_name
Front Mol Neuroscijournal_title
Frontiers in molecular neuroscienceauthors
Schlichting M,Rieger D,Cusumano P,Grebler R,Costa R,Mazzotta GM,Helfrich-Förster Cdoi
10.3389/fnmol.2018.00238subject
Has Abstractpub_date
2018-07-18 00:00:00pages
238issn
1662-5099journal_volume
11pub_type
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