Effects of Chronic Social Stress and Maternal Intranasal Oxytocin and Vasopressin on Offspring Interferon-γ and Behavior.

abstract：:Spontaneous and oxytocin induced contractile activity was quantified in the bicornuate uteri of pregnant rabbits maintained in situ, using data from two- and uni- dimensional video spatiotemporal maps (VSTM) of linear and area strain rate and compared statistically. Spontaneous contractions occurred over a range of fr...

journal_title：Frontiers in endocrinology

authors： Hulls CM,Lentle RG,Chua WH,Suisted P,King QM,Chagas JAB,Chambers JP,Stewart L

更新日期：2019-11-21 00:00:00

abstract：:The mammalian genome contains four genes encoding GABA transporters (GAT1, slc6a1; GAT2, slc6a13; GAT3, slc6a11; BGT1, slc6a12) and five glutamate transporter genes (EAAT1, slc1a3; EAAT2, slc1a2; EAAT3, slc1a1; EAAT4, slc1a6; EAAT5, slc1a7). These transporters keep the extracellular levels of GABA and excitatory amino...

journal_title：Frontiers in endocrinology

authors： Zhou Y,Danbolt NC

更新日期：2013-11-11 00:00:00

abstract：:Intrauterine growth restriction (IUGR) is a complex global healthcare issue. Concerted research and clinical efforts have improved our knowledge of the neurodevelopmental sequelae of IUGR which has raised the profile of this complex problem. Nevertheless, there is still a lack of therapies to prevent the substantial r...

journal_title：Frontiers in endocrinology

authors： Fleiss B,Wong F,Brownfoot F,Shearer IK,Baud O,Walker DW,Gressens P,Tolcos M

更新日期：2019-03-29 00:00:00

abstract：:The neurosteroids progesterone and allopregnanolone regulate numerous neuroprotective functions in neural tissues including inhibition of epileptic seizures and cell death. Many of progesterone's actions are mediated through the nuclear progesterone receptor (PR), while allopregnanolone is widely considered to be devo...

journal_title：Frontiers in endocrinology

authors： Thomas P,Pang Y

更新日期：2020-06-24 00:00:00

abstract：Background:It is well known that adiposity is a risk factor for insulin resistance and type 2 diabetes mellitus. In the present study, we aimed to investigate the associations of measures of adiposity with indices of glycemia and of glycemic variability over a 72-h period in non-diabetic older adults. Methods:This cro...

journal_title：Frontiers in endocrinology

authors： Noordam R,Huurman NC,Wijsman CA,Akintola AA,Jansen SWM,Stassen S,Beekman M,van de Rest O,Slagboom PE,Mooijaart SP,van Heemst D

更新日期：2018-05-14 00:00:00

abstract：BACKGROUND:Monitoring blood levels of human growth hormone (hGH) in most children with short stature deficiencies is crucial for taking a decision of treatment with extended course of daily and expensive doses of recombinant hGH (rhGH or Somatropin®). Besides, misusing of rhGH by sportsmen is banned by the World Anti-D...

journal_title：Frontiers in endocrinology

authors： Murad H,Assaad JM,Al-Shemali R,Abbady AQ

更新日期：2017-05-30 00:00:00

abstract：:Background: Associations between vitiligo and thyroid disorders have been suggested, However, the prevalence of thyroid disorders in vitiligo vary widely. Purpose: To conduct a systematic review and meta-analysis assessing the prevalence of thyroid disorders in patients with vitiligo. Method: The PubMed, Cochrane Libr...

journal_title：Frontiers in endocrinology

authors： Yuan J,Sun C,Jiang S,Lu Y,Zhang Y,Gao XH,Wu Y,Chen HD

更新日期：2019-01-15 00:00:00

abstract：:Rationale: Hypoxia induces leptin gene expression in human adipocytes via hypoxia-inducible factors (HIF-α/β). Under ambient moderate hypoxia, leptin in adipocytes is elevated for at least 14 days. Leptin is supposedly involved in the reduced food intake, increased utilization of fatty acids for energy production and ...

journal_title：Frontiers in endocrinology

authors： Rausch LK,Hofer M,Pramsohler S,Kaser S,Ebenbichler C,Haacke S,Gatterer H,Netzer NC

更新日期：2018-10-18 00:00:00

abstract：Background:Many studies suggest that the small ubiquitin-like modifier 4 (SUMO4) M55V gene polymorphism (rs237025) may be associated with an increased risk of type 2 diabetes mellitus (T2DM). However, due to other conflicting results, a clear consensus is lacking in the matter. Objective and methods:A meta-analysis co...

journal_title：Frontiers in endocrinology

authors： Li YY,Wang H,Yang XX,Geng HY,Gong G,Kim HJ,Zhou YH,Wu JJ

更新日期：2017-11-02 00:00:00

abstract：:Vitamin D is important for bone health, but may also have extra-skeletal effects. Vitamin D and its binding protein DBP have immunological effects and may therefore be important in the development of type 1 diabetes (T1DM), and low serum levels of 25-hydroxyvitamin D (25(OH)D) are associated with later development of ...

journal_title：Frontiers in endocrinology

authors： Jorde R

更新日期：2019-02-19 00:00:00

abstract：:Obesity is a multifactorial metabolic disorder characterized by low-grade chronic inflammation, hyper-permeability of the gut epithelium, and perturbation of the intestinal microbiome. Despite the numerous therapeutic efficacies of Dictyophora indusiata mushroom, its biological activity in alleviating obesity through ...

journal_title：Frontiers in endocrinology

authors： Kanwal S,Aliya S,Xin Y

更新日期：2020-11-19 00:00:00

abstract：:Both males and females of heliothine moths utilize sex-pheromones during the mating process. Females produce and release a sex pheromone for the long-range attraction of males for mating. Production of sex pheromone in females is controlled by the peptide hormone (pheromone biosynthesis activating neuropeptide, PBAN)....

journal_title：Frontiers in endocrinology

authors： Jurenka R,Rafaeli A

更新日期：2011-10-10 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fendo.2018.00031.]. ...

journal_title：Frontiers in endocrinology

authors： Beattie J,Al-Khafaji H,Noer PR,Alkharobi HE,Alhodhodi A,Meade J,El-Gendy R,Oxvig C

更新日期：2018-09-04 00:00:00

abstract：:Hashimoto's thyroiditis (HT) is the most common cause of thyroid disease in children and adolescents. Along with significant modifications of thyroid function, HT in pediatric age can be accompanied by relevant thyroid structural alterations. Over time, benign thyroid nodules, carcinoma and, rarely, primary non-Hodgki...

journal_title：Frontiers in endocrinology

authors： Penta L,Cofini M,Lanciotti L,Leonardi A,Principi N,Esposito S

更新日期：2018-10-09 00:00:00

abstract：:Background: The health benefits of soy are widely reported but there are queries on the effect of soy isoflavones on thyroid function and the underlying mechanism of action. Materials and Methods: We examined the effect of soy isoflavones on reverse tri-iodothyronine (or 3,3',5'-tri-iodothyronine; rT3) in two studies ...

journal_title：Frontiers in endocrinology

authors： Sathyapalan T,Köhrle J,Rijntjes E,Rigby AS,Dargham SR,Kilpatrick ES,Atkin SL

更新日期：2018-11-22 00:00:00

abstract：:Primary small cell carcinoma of the breast (SCCB) is a rare tumor subtype comprising <0.1% of all breast carcinomas. Here we present a case of thyroid transcription factor-1 (TTF-1) positive SCCB that recurred within 3 years of diagnosis in the lung and lymph nodes. Given the small number of cases, no clear guidelines...

journal_title：Frontiers in endocrinology

authors： Boutrid H,Kassem M,Tozbikian G,Morgan E,White J,Shah M,Vandeusen J,Sardesai S,Williams N,Stover DG,Lustberg M,Wesolowski R,Pudavalli V,Williams TM,Konda B,Fortier S,Carbone D,Ramaswamy B,Cherian MA

更新日期：2020-04-29 00:00:00

abstract：:Failure of uterine vascular transformation is associated with pregnancy complications including Intra Uterine Growth Restriction (IUGR). The decidua and its immune cell populations play a key role in the earliest stages of this process. Here we investigate the hypothesis that abnormal decidualization and failure of ma...

journal_title：Frontiers in endocrinology

authors： Dunk C,Kwan M,Hazan A,Walker S,Wright JK,Harris LK,Jones RL,Keating S,Kingdom JCP,Whittle W,Maxwell C,Lye SJ

更新日期：2019-03-20 00:00:00

abstract：Background:Renal function is profoundly influenced by thyroid hormone levels. This study was designed to evaluate the association between preoperative thyroid hormones and postoperative acute kidney injury (AKI) in acute type A aortic dissection (ATAAD) patients. Methods:A total of 88 patients with ATAAD who underwent...

journal_title：Frontiers in endocrinology

authors： Liu J,Xue Y,Jiang W,Zhang H,Zhao Y

更新日期：2020-11-18 00:00:00

abstract：:Background: Previous studies have confirmed that APOE genotype is associated with lipid metabolism, but related studies are inconsistent. Therefore, we conducted this cross-sectional study to explore the associations between apolipoprotein E (APOE) genotypes and serum levels of fasting blood sugar, triglycerides, tota...

journal_title：Frontiers in endocrinology

authors： Li W,Li Y,Qiu Q,Sun L,Yue L,Li X,Xiao S

更新日期：2019-12-05 00:00:00

abstract：:Calcium and bone homeostasis are intimately related. On the one hand, bone relies on a sufficient supply of calcium to maintain its structural and mechanical properties and thus largely depends on calcium absorption in the intestine and calcium reabsorption in the kidney. On the other hand, bone serves as a calcium re...

journal_title：Frontiers in endocrinology

authors： Lieben L,Carmeliet G

更新日期：2012-08-20 00:00:00

abstract：:The p53-related gene p63 is required for epithelial cell establishment and its expression is often altered in tumor cells. Great strides have been made in understanding the pathways and mechanisms that regulate p63 levels, such as the Wnt, Hedgehog, Notch, and EGFR pathways. We discuss here the multiple signaling path...

journal_title：Frontiers in endocrinology

authors： Yoh K,Prywes R

更新日期：2015-04-28 00:00:00

abstract：:Human studies support a strong association between hypertriglyceridemia and atherosclerotic cardiovascular disease (CVD). However, whether a causal relationship exists between hypertriglyceridemia and increased CVD risk is still unclear. One plausible explanation for the difficulty establishing a clear causal role for...

journal_title：Frontiers in endocrinology

authors： Basu D,Bornfeldt KE

更新日期：2020-08-06 00:00:00

abstract：:Initially identified as monomers, G protein-coupled receptors (GPCRs) can also form functional homo- and heterodimers that act as distinct signaling hubs for cellular signal integration. We previously found that the angiotensin II (Ang II) type 1 receptor (AT1R) and the prostaglandin F2α (PGF2α) receptor (FP), both im...

journal_title：Frontiers in endocrinology

authors： Fillion D,Devost D,Sleno R,Inoue A,Hébert TE

更新日期：2019-03-18 00:00:00

abstract：:Background: Improved understanding of the pathophysiology causing diabetic kidney disease (DKD) is imperative. The aim of this study was to uncover associations between serum metabolites and renal outcomes. Methods: Non-targeted serum metabolomics analyses were performed in samples from 637 persons with type 1 diabete...

journal_title：Frontiers in endocrinology

authors： Tofte N,Suvitaival T,Trost K,Mattila IM,Theilade S,Winther SA,Ahluwalia TS,Frimodt-Møller M,Legido-Quigley C,Rossing P

更新日期：2019-11-22 00:00:00

abstract：:Osteoporosis is a metabolic skeletal disorder in which bone mass is depleted and bone structure is destroyed to the degree that bone becomes fragile and prone to fractures. Emerging evidence suggests that N6-methyladenosine (m6A) modification, a novel epitranscriptomic marker, has a significant role in bone developmen...

journal_title：Frontiers in endocrinology

authors： Chen X,Hua W,Huang X,Chen Y,Zhang J,Li G

更新日期：2020-01-10 00:00:00

abstract：:Prostate cancer (PCa) is the major cause of cancer-related death among the male population of Western society, and androgen-deprivation therapy (ADT) represents the first line in PCa treatment. However, although androgen receptor (AR) expression is maintained throughout the various stages of PCa, ADT frequently fails....

journal_title：Frontiers in endocrinology

authors： Di Donato M,Giovannelli P,Cernera G,Di Santi A,Marino I,Bilancio A,Galasso G,Auricchio F,Migliaccio A,Castoria G

更新日期：2015-01-19 00:00:00

abstract：:The brain is composed of neurons and non-neuronal cells, with the latter encompassing glial, ependymal and endothelial cells, as well as pericytes and progenitor cells. Studies aimed at understanding how the brain operates have traditionally focused on neurons, but the importance of non-neuronal cells has become incre...

journal_title：Frontiers in endocrinology

authors： Argente-Arizón P,Freire-Regatillo A,Argente J,Chowen JA

更新日期：2015-03-26 00:00:00

abstract：:Breast cancer (BC) is one of the most common malignancies and the leading cause of cancer-related mortality in women. Androgen receptor (AR) is frequently expressed in diverse BC subtypes. Accumulating evidence has revealed that AR might be a predictive or prognostic factor and a drug target in BC. AR expression and A...

journal_title：Frontiers in endocrinology

authors： Chen M,Yang Y,Xu K,Li L,Huang J,Qiu F

更新日期：2020-09-02 00:00:00

abstract：:Obesity is a prominent metabolic disease that predisposes individuals to multiple comorbidities, including type 2 diabetes mellitus, cardiovascular diseases, and cancer. Elevated circulating levels of fatty acids contribute to the development of obesity, in part, by targeting the hypothalamus. Palmitate, the most abun...

journal_title：Frontiers in endocrinology

authors： Tran A,He W,Jiang N,Chen JTC,Belsham DD

更新日期：2020-06-12 00:00:00

abstract：:Objective: Prolactin and progesterone are implicated in glucose homeostasis in and outside of pregnancy. However, their associations with gestational diabetes (GDM) risk were not well-understood. This study investigates this question in a prospective and longitudinal cohort. Methods: This is a nested case-control stud...

journal_title：Frontiers in endocrinology

authors： Li M,Song Y,Rawal S,Hinkle SN,Zhu Y,Tekola-Ayele F,Ferrara A,Tsai MY,Zhang C

更新日期：2020-02-27 00:00:00