Closed-Loop Neuromorphic Benchmarks.

abstract：:Recent intriguing evidence suggests that metabolites of amyloid precursor protein (APP), mutated in familial forms of Alzheimer's disease (AD), play critical roles in developmental and postnatal neurogenesis. Of note is soluble APPα (sAPPα) that regulates neural progenitor cell proliferation. The APP family encompasse...

journal_title：Frontiers in neuroscience

authors： Lazarov O,Demars MP

更新日期：2012-06-04 00:00:00

abstract：:The utility of premovement electroencephalography (EEG) for decoding movement intention during a reaching task has been demonstrated. However, the kind of information the brain represents regarding the intended target during movement preparation remains unknown. In the present study, we investigated which movement par...

journal_title：Frontiers in neuroscience

authors： Kim H,Yoshimura N,Koike Y

更新日期：2019-11-01 00:00:00

abstract：:The neurodegenerative disorder multiple system atrophy (MSA) is characterized by autonomic failure, cerebellar ataxia and parkinsonism in any combination associated with predominantly oligodendroglial α-synuclein (α-syn) aggregates (glial cytoplasmic inclusions = GCIs). To date, there is no effective disease modifying...

journal_title：Frontiers in neuroscience

authors： Fellner L,Kuzdas-Wood D,Levin J,Ryazanov S,Leonov A,Griesinger C,Giese A,Wenning GK,Stefanova N

更新日期：2016-03-10 00:00:00

abstract：:Although, cochlear implants (CI) traditionally have been used to treat individuals with bilateral profound sensorineural hearing loss, a recent trend is to implant individuals with residual low-frequency hearing. Notably, many of these individuals demonstrate an air-bone gap (ABG) in low-frequency, pure-tone threshold...

journal_title：Frontiers in neuroscience

authors： Koka K,Saoji AA,Attias J,Litvak LM

更新日期：2017-04-18 00:00:00

abstract：:The efficacy of neuronal function requires a well-balanced extracellular ion homeostasis and a steady supply with nutrients and metabolites. Therefore, all organisms equipped with a complex nervous system developed a so-called blood-brain barrier, protecting it from an uncontrolled entry of solutes, metabolites or pat...

journal_title：Frontiers in neuroscience

authors： Limmer S,Weiler A,Volkenhoff A,Babatz F,Klämbt C

更新日期：2014-11-14 00:00:00

abstract：:Recent non-invasive brain stimulation techniques in combination with motor training can enhance neuroplasticity and learning. It is reasonable to assume that such neuroplasticity-based interventions constitute a useful rehabilitative tool for patients with Parkinson's Disease (PD). Regarding motor skill training, many...

journal_title：Frontiers in neuroscience

authors： Horiba M,Ueki Y,Nojima I,Shimizu Y,Sahashi K,Itamoto S,Suzuki A,Yamada G,Matsukawa N,Wada I

更新日期：2019-06-19 00:00:00

abstract：:Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) mediated by T helper (h)1 and/or Th17 CD4 T cells that drive inflammatory lesion development along with demyelination and neuronal damage. Defects in immune regulatory mechanisms are thought to play a role in the pathogenesis of MS. W...

journal_title：Frontiers in neuroscience

authors： Miller NM,Wang J,Tan Y,Dittel BN

更新日期：2015-08-18 00:00:00

abstract：:Chemical communication via sex pheromones is critical for successful reproduction but the underlying neural mechanisms are not well-understood. The goldfish is a tractable model because sex pheromones have been well-characterized in this species. We used male goldfish forebrain explants in vitro and performed whole-ce...

journal_title：Frontiers in neuroscience

authors： Lado WE,Spanswick DC,Lewis JE,Trudeau VL

更新日期：2014-06-30 00:00:00

abstract：:The comprehension of fluent speech in one's native language requires that listeners integrate the detailed acoustic-phonetic information available in the sound signal with linguistic knowledge. This interplay is especially apparent in the phoneme restoration effect, a phenomenon in which a missing phoneme is "restored...

journal_title：Frontiers in neuroscience

authors： Del Tufo SN,Myers EB

更新日期：2014-06-04 00:00:00

abstract：:Cochlear implantation constitutes a successful therapy of inner ear deafness, with the majority of patients showing good outcomes. There is, however, still some unexplained variability in outcomes with a number of cochlear-implant (CI) users, showing major limitations in speech comprehension. The current study used a ...

journal_title：Frontiers in neuroscience

authors： Kessler M,Schierholz I,Mamach M,Wilke F,Hahne A,Büchner A,Geworski L,Bengel FM,Sandmann P,Berding G

更新日期：2020-08-11 00:00:00

abstract：:Background: Stroke is the second leading cause of death worldwide. Angiogenesis facilitates the formation of microvascular networks and promotes recovery after stroke. The Shh/Gli signaling pathway is implicated in angiogenesis and cerebral ischemia-reperfusion (I/R) injury. This study aimed at investigating the influ...

journal_title：Frontiers in neuroscience

authors： Peng L,Yin J,Ge M,Wang S,Xie L,Li Y,Si JQ,Ma K

更新日期：2019-04-09 00:00:00

abstract：:For safe application of exoskeletons in people with spinal cord injury at home or in the community, it is required to have completed an exoskeleton training in which users learn to perform basic and advanced skills. So far, a framework to test exoskeleton skills is lacking. The aim of this study was to develop and tes...

journal_title：Frontiers in neuroscience

authors： van Dijsseldonk RB,Rijken H,van Nes IJW,van de Meent H,Keijsers NLW

更新日期：2017-12-12 00:00:00

abstract：:Alcohol and drug dependence are serious public health problems worldwide. The prevalence of alcohol and drug dependence in the United States and other parts of the world is significant. Given the limitations in the efficacy of current pharmacotherapies to treat these disorders, research in developing alternative pharm...

journal_title：Frontiers in neuroscience

authors： Rahman S,Engleman EA,Bell RL

更新日期：2015-01-15 00:00:00

abstract：:Corticotropin-releasing factor (CRF) is a 41-amino acid neuropeptide that is involved in stress-related physiology and behavior, including control of the hypothalamic-pituitary-adrenal (HPA) axis. Members of the CRF family of neuropeptides, including urocortin 1 (UCN 1), UCN 2, and UCN 3, bind to the G protein-coupled...

journal_title：Frontiers in neuroscience

authors： Fox JH,Lowry CA

更新日期：2013-09-20 00:00:00

abstract：:Accumulation of misfolded proteins results in cellular stress, and is detected by specific sensors in the endoplasmic reticulum, collectively known as the unfolded protein response (UPR). It has been prominently proposed that the UPR is involved in the pathophysiology of Parkinson's disease (PD). In the present study,...

journal_title：Frontiers in neuroscience

authors： Baek JH,Mamula D,Tingstam B,Pereira M,He Y,Svenningsson P

更新日期：2019-07-05 00:00:00

abstract：:This paper presents a unique approach for wavelet-based MRI brain image de-noising. Adaptive soft and hard threshold functions are first proposed to improve the results of standard soft and hard threshold functions for image de-noising in the wavelet domain. Then, we applied the newly emerged improved adaptive general...

journal_title：Frontiers in neuroscience

authors： Amiri Golilarz N,Gao H,Kumar R,Ali L,Fu Y,Li C

更新日期：2020-07-22 00:00:00

abstract：:Cognitive control of emotions depends on intermodular long-distance communications. However, negative connections between connector hubs are removed by traditional hard-thresholding approach in graph-theoretical research. Using soft-thresholding approach to reserve negative links, we explore time-varying features of c...

journal_title：Frontiers in neuroscience

authors： Zhang W,Chen J,Ren G,Tang F,Liu Q,Li H

更新日期：2019-10-25 00:00:00

abstract：:The mammalian brain is characterized by orderly spatial distribution of its cellular components, commonly referred to as topographical organization. The topography of cortical and subcortical maps is thought to represent functional or computational properties. In the present investigation, we have studied map transfor...

journal_title：Frontiers in neuroscience

authors： Leergaard TB,Bjaalie JG

更新日期：2007-10-15 00:00:00

abstract：:We previously demonstrated that, in the early stages of tau processing in Alzheimer's disease, the N-terminal part of the molecule undergoes a characteristic cascade of phosphorylation and progressive misfolding of the proteins resulting in a structural conformation detected by Alz-50. In this immunohistochemical stud...

journal_title：Frontiers in neuroscience

authors： Flores-Rodríguez P,Ontiveros-Torres MA,Cárdenas-Aguayo MC,Luna-Arias JP,Meraz-Ríos MA,Viramontes-Pintos A,Harrington CR,Wischik CM,Mena R,Florán-Garduño B,Luna-Muñoz J

更新日期：2015-02-11 00:00:00

abstract：:Background: The relationship between awareness and attention is complex and controversial. A growing body of literature has shown that the neural bases of consciousness and endogenous attention (voluntary attention) are independent. The important role of exogenous attention (reflexive attention) on conscious experienc...

journal_title：Frontiers in neuroscience

authors： Chen Y,Wang X,Yu Y,Liu Y

更新日期：2017-11-13 00:00:00

abstract：:Modern high field and ultra high field magnetic resonance imaging (MRI) experiments routinely collect multi-dimensional data with high spatial resolution, whether multi-parametric structural, diffusion or functional MRI. While diffusion and functional imaging have benefited from recent advances in multi-dimensional si...

journal_title：Frontiers in neuroscience

authors： Bazin PL,Alkemade A,van der Zwaag W,Caan M,Mulder M,Forstmann BU

更新日期：2019-10-09 00:00:00

abstract：:Schizophrenia is a complex disorder about which much is still unknown. Potential treatments, such as transcranial magnetic stimulation (TMS), have not been exploited, in part because of the variability in behavioral response. This can be overcome with the use of response biomarkers. It has been however shown that repe...

journal_title：Frontiers in neuroscience

authors： Aubonnet R,Banea OC,Sirica R,Wassermann EM,Yassine S,Jacob D,Magnúsdóttir BB,Haraldsson M,Stefansson SB,Jónasson VD,Ívarsson E,Jónasson AD,Hassan M,Gargiulo P

更新日期：2020-11-20 00:00:00

abstract：:For brain-computer interfaces (BCIs) that utilize visual cues to direct the user, the neural signals extracted by the computer are representative of ongoing processes, visual evoked responses, and voluntary modulation. We proposed to use three brain signatures for predicting success on a single trial of a BCI task. Th...

journal_title：Frontiers in neuroscience

authors： Geronimo A,Kamrunnahar M,Schiff SJ

更新日期：2016-04-26 00:00:00

abstract：:Orexins are hypothalamic neuropeptides that were initially identified in the rat brain as endogenous ligands for an (previously) orphan G-protein-coupled receptor (GPCR). They are multitasking peptides involved in many physiological functions, including regulation of feeding behavior, wakefulness and autonomic/neuroen...

journal_title：Frontiers in neuroscience

authors： Soya S,Sakurai T

更新日期：2020-07-10 00:00:00

abstract：:Vagal neurocircuits are vitally important in the co-ordination and modulation of GI reflexes and homeostatic functions. 5-hydroxytryptamine (5-HT; serotonin) is critically important in the regulation of several of these autonomic gastrointestinal (GI) functions including motility, secretion and visceral sensitivity. W...

journal_title：Frontiers in neuroscience

authors： Browning KN

更新日期：2015-10-29 00:00:00

abstract：:The structural organization of cortical areas is not random, with topographic maps commonplace in sensory processing centers. This topographical organization allows optimal wiring between neurons, multimodal sensory integration, and performs input dimensionality reduction. In this work, a model of topographic map form...

journal_title：Frontiers in neuroscience

authors： Bogdan PA,Rowley AGD,Rhodes O,Furber SB

更新日期：2018-07-02 00:00:00

abstract：:We generally experience a stable visual world in spite of regular disruptions caused by our own movements (saccades, blinks) or by the visual input itself (flashes, occlusions). In trying to understand the mechanisms responsible for this stability, saccades have been particularly well-studied, and a number of peri-sac...

journal_title：Frontiers in neuroscience

authors： Chota S,McLelland D,Lavergne L,Zimmermann E,Cavanagh P,VanRullen R

更新日期：2020-03-17 00:00:00

abstract：:Data from animal models and Alzheimer's disease (AD) subjects provide clear evidence for an activation of inflammatory pathways during the pathogenetic course of such illness. Biochemical and neuropathological studies highlighted an important cause/effect relationship between inflammation and AD progression, revealing...

journal_title：Frontiers in neuroscience

authors： Steardo L Jr,Bronzuoli MR,Iacomino A,Esposito G,Steardo L,Scuderi C

更新日期：2015-07-29 00:00:00

abstract：:Neurologic Music Therapy (NMT) is a novel impairment-focused behavioral intervention system whose techniques are based on the clinical neuroscience of music perception, cognition, and production. Auditory Stimulation (RAS) is one of the NMT techniques, which aims to develop and maintain a physiological rhythmic motor ...

journal_title：Frontiers in neuroscience

authors： Buard I,Dewispelaere WB,Thaut M,Kluger BM

更新日期：2019-02-19 00:00:00

abstract：:Brain functional connectivity network (BFCN) analysis has been widely used in the diagnosis of mental disorders, such as schizophrenia. In BFCN methods, brain network construction is one of the core tasks due to its great influence on the diagnosis result. Most of the existing BFCN construction methods only consider t...

journal_title：Frontiers in neuroscience

authors： Zhu Q,Li H,Huang J,Xu X,Guan D,Zhang D

更新日期：2019-06-14 00:00:00