GRP78 Level Is Altered in the Brain, but Not in Plasma or Cerebrospinal Fluid in Parkinson's Disease Patients.

abstract：:High angular resolution diffusion imaging (HARDI)-based tractography has been increasingly used in longitudinal studies on white matter macro- and micro-structural changes in the language network during language acquisition and in language impairments. However, test-retest reliability measurements are essential to asc...

journal_title：Frontiers in neuroscience

authors： Boukadi M,Marcotte K,Bedetti C,Houde JC,Desautels A,Deslauriers-Gauthier S,Chapleau M,Boré A,Descoteaux M,Brambati SM

更新日期：2019-01-14 00:00:00

abstract：:Opioid abuse is now the primary cause of accidental deaths in the United States. Studies over several decades established the cyclical nature of abused drugs of choice, with a current resurgence of heroin abuse and, more recently, fentanyl's emergence as a major precipitant of drug-related deaths. To better understand...

journal_title：Frontiers in neuroscience

authors： Saad MH,Savonen CL,Rumschlag M,Todi SV,Schmidt CJ,Bannon MJ

更新日期：2018-10-23 00:00:00

abstract：:The habenular neural circuit is attracting increasing attention from researchers in fields as diverse as neuroscience, medicine, behavior, development, and evolution. Recent studies have revealed that this part of the limbic system in the dorsal diencephalon is involved in reward, addiction, and other behaviors and it...

journal_title：Frontiers in neuroscience

authors： Beretta CA,Dross N,Guiterrez-Triana JA,Ryu S,Carl M

更新日期：2012-04-23 00:00:00

abstract：:The prevalence of depressive disorders is growing worldwide, notably due to stagnation in the development of drugs with greater antidepressant efficacy, the continuous large proportion of patients who do not respond to conventional antidepressants, and the increasing rate of chronic medical conditions associated with ...

journal_title：Frontiers in neuroscience

authors： Vancassel S,Capuron L,Castanon N

更新日期：2018-07-24 00:00:00

abstract：:Alzheimer's disease (AD) is a neurocognitive disorder that impacts both the brain and behavior. Metal ions, including zinc (Zn), have been seen to play an important role in AD-related pathology. In this study, we show alterations in wheel-running behavior both early and late in disease progression in a novel dual Tg m...

journal_title：Frontiers in neuroscience

authors： Lippi SLP,Kakalec PA,Smith ML,Flinn JM

更新日期：2020-08-14 00:00:00

abstract：:Neuromorphic systems are gaining increasing importance in an era where CMOS digital computing techniques are reaching physical limits. These silicon systems mimic extremely energy efficient neural computing structures, potentially both for solving engineering applications as well as understanding neural computation. T...

journal_title：Frontiers in neuroscience

authors： Hasler J,Marr B

更新日期：2013-09-10 00:00:00

abstract：:While neuromorphic systems may be the ultimate platform for deploying spiking neural networks (SNNs), their distributed nature and optimization for specific types of models makes them unwieldy tools for developing them. Instead, SNN models tend to be developed and simulated on computers or clusters of computers with s...

journal_title：Frontiers in neuroscience

authors： Knight JC,Nowotny T

更新日期：2018-12-12 00:00:00

abstract：:Increasingly, neuroimaging researchers are exploring the use of real-time functional magnetic resonance imaging (rt-fMRI) as a way to access a participant's ongoing brain function throughout a scan. This approach presents novel and exciting experimental applications ranging from monitoring data quality in real time, t...

journal_title：Frontiers in neuroscience

authors： MacInnes JJ,Adcock RA,Stocco A,Prat CS,Rao RPN,Dickerson KC

更新日期：2020-09-15 00:00:00

abstract：:Chronic glial activation is characterized by an increased number of activated microglia and astroglia; these secrete free radicals and cytotoxic cytokines, subsequently causing neuronal damage. This study investigated the hypothesis that a soy-lecithin based phytosomal curcumin formulation can decrease glial activatio...

journal_title：Frontiers in neuroscience

authors： Ullah F,Liang H,Niedermayer G,Münch G,Gyengesi E

更新日期：2020-03-12 00:00:00

abstract：:Social memory, including the ability to recognize faces and voices, is essential for social relationships. It has a large heritable component, but the knowledge about the contributing genes is sparse. The genetic variation underlying inter-individual differences in social memory was investigated in an exploratory samp...

journal_title：Frontiers in neuroscience

authors： Henningsson S,Zettergren A,Hovey D,Jonsson L,Svärd J,Cortes DS,Melke J,Ebner NC,Laukka P,Fischer H,Westberg L

更新日期：2015-10-21 00:00:00

abstract：:Experiment was carried out to study the proprioception accuracy of elderly (61-83 years old) and young (22-36 years old) subjects during contralateral elbow matching in sagittal plane. The subjects performed the task under ordinary condition and under experimental condition (matching forearm attached to the rocking cy...

journal_title：Frontiers in neuroscience

authors： Talis VL,Levik YS

更新日期：2016-11-16 00:00:00

abstract：:Silver nano-particles (Ag-NPs) are becoming increasingly prevalent in consumer products as antibacterial agents. The increased use of Ag NP-enhanced products will almost certainly increase environmental silver levels, resulting in increased exposures and the potential for increased adverse reactions including neurotox...

journal_title：Frontiers in neuroscience

authors： Liu F,Mahmood M,Xu Y,Watanabe F,Biris AS,Hansen DK,Inselman A,Casciano D,Patterson TA,Paule MG,Slikker W Jr,Wang C

更新日期：2015-04-08 00:00:00

abstract：:Identifying the multiple contributors to the audiometric loss of a hearing impaired (HI) listener at a particular frequency is becoming gradually more useful as new treatments are developed. Here, we infer the contribution of inner (IHC) and outer hair cell (OHC) dysfunction to the total audiometric loss in a sample o...

journal_title：Frontiers in neuroscience

authors： Johannesen PT,Pérez-González P,Lopez-Poveda EA

更新日期：2014-07-23 00:00:00

abstract：:We review the role of oscillations in the brain and in the auditory system showing that the ability of humans to distinguish changes in pitch can be explained as a precise analysis of temporal information in auditory signals by neural oscillations. The connections between auditory brain stem chopper neurons construct ...

journal_title：Frontiers in neuroscience

authors： Bahmer A,Gupta DS

更新日期：2018-10-31 00:00:00

abstract：:In order to characterize the genetic architecture of epilepsy in a pediatric population from the Iberian Peninsula (including the Canary Islands), we conducted targeted exome sequencing of 246 patients with infantile-onset seizures with or without neurodevelopmental delay. We detected 107 variants in 48 different gene...

journal_title：Frontiers in neuroscience

authors： Fernández-Marmiesse A,Roca I,Díaz-Flores F,Cantarín V,Pérez-Poyato MS,Fontalba A,Laranjeira F,Quintans S,Moldovan O,Felgueroso B,Rodríguez-Pedreira M,Simón R,Camacho A,Quijada P,Ibanez-Mico S,Domingno MR,Benito C,Calvo

更新日期：2019-11-08 00:00:00

abstract：:Electroencephalography (EEG) is perhaps the most widely used brain-imaging technique for pediatric populations. However, EEG signals are prone to distortion by motion. Compared to adults, infants' motion is both more frequent and less stereotypical yet motion effects on the infant EEG signal are largely undocumented. ...

journal_title：Frontiers in neuroscience

authors： Georgieva S,Lester S,Noreika V,Yilmaz MN,Wass S,Leong V

更新日期：2020-04-28 00:00:00

abstract：:We previously demonstrated that, in the early stages of tau processing in Alzheimer's disease, the N-terminal part of the molecule undergoes a characteristic cascade of phosphorylation and progressive misfolding of the proteins resulting in a structural conformation detected by Alz-50. In this immunohistochemical stud...

journal_title：Frontiers in neuroscience

authors： Flores-Rodríguez P,Ontiveros-Torres MA,Cárdenas-Aguayo MC,Luna-Arias JP,Meraz-Ríos MA,Viramontes-Pintos A,Harrington CR,Wischik CM,Mena R,Florán-Garduño B,Luna-Muñoz J

更新日期：2015-02-11 00:00:00

abstract：:In the past, determination of absolute values of cerebral metabolic rate of glucose (CMRGlc) in clinical routine was rarely carried out due to the invasive nature of arterial sampling. With the advent of combined PET/MR imaging technology, CMRGlc values can be obtained non-invasively, thereby providing the opportunity...

journal_title：Frontiers in neuroscience

authors： Shiyam Sundar LK,Baajour S,Beyer T,Lanzenberger R,Traub-Weidinger T,Rausch I,Pataraia E,Hahn A,Rischka L,Hienert M,Klebermass EM,Muzik O

更新日期：2020-03-25 00:00:00

abstract：:The linearity and stationarity of fMRI time series need to be understood due to their important roles in the choice of approach for brain network analysis. In this paper, we investigated the stationarity and linearity of resting-state fMRI (rs-fMRI) time-series data from the Midnight Scan Club datasets. The degree of ...

journal_title：Frontiers in neuroscience

authors： Guan S,Jiang R,Bian H,Yuan J,Xu P,Meng C,Biswal B

更新日期：2020-06-11 00:00:00

abstract：:Musical training has recently gained additional interest in education as increasing neuroscientific research demonstrates its positive effects on brain development. Neuroimaging revealed plastic changes in the brains of adult musicians but it is still unclear to what extent they are the product of intensive music trai...

journal_title：Frontiers in neuroscience

authors： Miendlarzewska EA,Trost WJ

更新日期：2014-01-20 00:00:00

abstract：:Induction of lordosis as typical female sexual behavior in rodents is dependent on a mount stimulus from males and blood levels of estrogen. Periaqueductal gray (PAG) efferent neurons have been suggested to be important for lordosis behavior; however, the neurochemical basis remains to be understood. In this study, we...

journal_title：Frontiers in neuroscience

authors： Yamada S,Kawata M

更新日期：2014-12-18 00:00:00

abstract：BACKGROUND:With the advent of the GeneChip Exon Arrays, it is now possible to extract "exon-level" expression estimates, allowing for detection of alternative splicing events, one of the primary mechanisms of transcript diversity. In the context of (1) a complex trait use case and (2) a human cerebellum vs. heart compa...

journal_title：Frontiers in neuroscience

authors： Laderas TG,Walter NA,Mooney M,Vartanian K,Darakjian P,Buck K,Harrington CA,Belknap J,Hitzemann R,McWeeney SK

更新日期：2011-05-13 00:00:00

abstract：:Ever since the modern rediscovery of psychedelic substances by Western society, several authors have independently proposed that their effects bear a high resemblance to the dreams and dreamlike experiences occurring naturally during the sleep-wake cycle. Recent studies in humans have provided neurophysiological evide...

journal_title：Frontiers in neuroscience

authors： Sanz C,Zamberlan F,Erowid E,Erowid F,Tagliazucchi E

更新日期：2018-01-22 00:00:00

abstract：:Self-control exertion on an initial task has been associated with impaired performance on subsequent physical tasks also requiring self-control; an effect suggested to be mediated by changes in perceptions of pain and motivation. However, the effects of spending longer on the initial self-control task are unknown. Thi...

journal_title：Frontiers in neuroscience

authors： Boat R,Hunte R,Welsh E,Dunn A,Treadwell E,Cooper SB

更新日期：2020-10-08 00:00:00

abstract：Background:Cochlear implants (CIs), which have been designed primarily to support spoken communication of persons with severe to profound hearing loss, are highly effective in supporting speech perception in quiet listening conditions. CI users as a group achieve significantly poorer perception and appraisal of music, ...

journal_title：Frontiers in neuroscience

authors： Gfeller K,Driscoll V,Schwalje A

更新日期：2019-11-21 00:00:00

abstract：:Dopamine system plays a pivotal role in specific kinds of substance use disorders (SUD, i. e., cocaine and methamphetamine use disorders). Many studies addressed whether dopamine-involved craving could be alleviated by non-invasive brain stimulation (NIBS) techniques. Nevertheless, the outcomes were highly inconsisten...

journal_title：Frontiers in neuroscience

authors： Ma T,Sun Y,Ku Y

更新日期：2019-10-18 00:00:00

abstract：Objective:Magnetic resonance-guided focused ultrasound surgery (MRgFUS) lesioning is a new treatment for brain disorders. However, the skull is a major barrier of ultrasound sonication in MRgFUS because it has an irregular surface and varies its size and shape among individuals. We recently developed the concept of sku...

journal_title：Frontiers in neuroscience

authors： Chang KW,Rachmilevitch I,Chang WS,Jung HH,Zadicario E,Prus O,Chang JW

更新日期：2021-01-12 00:00:00

abstract：:Up to now relatively little is known about interlimb reflexes (ILR). Especially it is not well known whether ILR may habituate or not to subsequent stimuli. The main aim of the present investigation was to explore the short term habituation behavior of ILR. The electromyogram was recorded over the tonically active bic...

journal_title：Frontiers in neuroscience

authors： Alaid S,Emmer A,Kornhuber ME

更新日期：2019-10-23 00:00:00

abstract：:Diffusion magnetic resonance imaging (dMRI) is a compelling tool for investigating the structure and geometry of brain tissue based on indirect measurement of the diffusion anisotropy of water. Recent developments in global top-down tractogram optimizations enable the estimation of streamline weights, which characteri...

journal_title：Frontiers in neuroscience

authors： Sommer S,Kozerke S,Seifritz E,Staempfli P

更新日期：2017-12-22 00:00:00

abstract：:Frontotemporal Dementia (FTD) is a focal neurodegenerative disease, with a strong genetic background, that causes early onset dementia. The present knowledge about the risk loci and causative mutations of FTD mainly derives from genetic linkage analysis, studies of candidate genes, Genome-Wide Association Studies (GWA...

journal_title：Frontiers in neuroscience

authors： Ciani M,Benussi L,Bonvicini C,Ghidoni R

更新日期：2019-05-16 00:00:00