RXFP1 is Targeted by Complement C1q Tumor Necrosis Factor-Related Factor 8 in Brain Cancer.

Abstract:

:The relaxin-like RXFP1 ligand-receptor system has important functions in tumor growth and tissue invasion. Recently, we have identified the secreted protein, CTRP8, a member of the C1q/tumor necrosis factor-related protein (CTRP) family, as a novel ligand of the relaxin receptor, RXFP1, with functions in brain cancer. Here, we review the role of CTRP members in cancers cells with particular emphasis on CTRP8 in glioblastoma.

authors

Thanasupawat T,Glogowska A,Burg M,Wong GW,Hoang-Vu C,Hombach-Klonisch S,Klonisch T

doi

10.3389/fendo.2015.00127

subject

Has Abstract

pub_date

2015-08-13 00:00:00

pages

127

issn

1664-2392

journal_volume

6

pub_type

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