Relationship between L-DOPA-induced reduction in motor and exploratory activity and degree of DAT binding in the rat.

abstract：:The last two decades of research provided evidence for a substantial heterogeneity among feeding-related neurons (FRNs) in the hypothalamus. However, it remains unclear how FRNs differ in their firing patterns during food intake. Here, we investigated the relationship between the activity of neurons in mouse hypothala...

journal_title：Frontiers in behavioral neuroscience

authors： Tang Y,Benusiglio D,Grinevich V,Lin L

更新日期：2016-05-18 00:00:00

abstract：:Environmental enrichment (EE) is an experimental setting broadly used for investigating the effects of complex social, cognitive, and sensorimotor stimulations on brain structure and function. Recent studies point out that parental EE experience, even occurring in the pre-reproductive phase, affects neural development...

journal_title：Frontiers in behavioral neuroscience

authors： Cutuli D,Berretta E,Pasqualini G,De Bartolo P,Caporali P,Laricchiuta D,Sampedro-Piquero P,Gelfo F,Pesoli M,Foti F,Begega A,Petrosini L

更新日期：2017-05-09 00:00:00

abstract：:Major advances in the past decade have led a better understanding of the pathophysiology of narcolepsy with cataplexy (NC) caused by the early loss of hypothalamic hypocretin neurons. Although a role for hypocretin in the regulation of sleep/wakefulness state is widely recognized, other functions, not necessarily rela...

journal_title：Frontiers in behavioral neuroscience

authors： Bayard S,Dauvilliers YA

更新日期：2013-05-23 00:00:00

abstract：:Emotional events gain special priority in how they are remembered, with emotionally arousing events typically recalled more vividly and with greater confidence than non-emotional events. In dementia, memory and emotion processing are affected to varying degrees, however, whether emotional enhancement of memory for com...

journal_title：Frontiers in behavioral neuroscience

authors： Kumfor F,Irish M,Hodges JR,Piguet O

更新日期：2014-06-24 00:00:00

abstract：:Interactions between social experiences at different stages of development (e.g., with parents as juveniles and peers as subadults) can profoundly shape the expression of social behavior. Rarely are the influences of more than one stage of developmental sensitivity to social environment investigated simultaneously. Fu...

journal_title：Frontiers in behavioral neuroscience

authors： Prounis GS,Ophir AG

更新日期：2019-09-13 00:00:00

abstract：:In the present review, we provide evidence indicating that although post traumatic stress disorder (PTSD) and substance use disorder (SUD) are two distinct pathologies with very different impacts on people affected by these chronic illnesses, they share numerous common characteristics, present high rates of co-morbidi...

journal_title：Frontiers in behavioral neuroscience

authors： Gisquet-Verrier P,Le Dorze C

更新日期：2019-02-13 00:00:00

abstract：:To gain further knowledge on the preclinical phase of Alzheimer's disease (AD), we sought to characterize cognitive performance, neuroimaging and plasma-based AD biomarkers in a cohort of non-demented adults with down syndrome (DS). The goal of the down syndrome biomarker Initiative (DSBI) pilot is to test feasibility...

journal_title：Frontiers in behavioral neuroscience

authors： Rafii MS,Wishnek H,Brewer JB,Donohue MC,Ness S,Mobley WC,Aisen PS,Rissman RA

更新日期：2015-09-14 00:00:00

abstract：:Aggressive behavior is thought to divide into two motivational elements: The first being a self-defensively motivated aggression against threat and a second, hedonically motivated "appetitive" aggression. Appetitive aggression is the less understood of the two, often only researched within abnormal psychology. Our app...

journal_title：Frontiers in behavioral neuroscience

authors： Moran JK,Weierstall R,Elbert T

更新日期：2014-12-09 00:00:00

abstract：:Stress disturbs the balance of the gut microbiota and stimulates inflammation-to-brain mechanisms. Moreover, stress leads to anxiety and depressive disorders. Bifidobacterium adolescentis displays distinct anti-inflammatory effects. However, no report has focused on the anxiolytic and antidepressant effects of B. adol...

journal_title：Frontiers in behavioral neuroscience

authors： Guo Y,Xie JP,Deng K,Li X,Yuan Y,Xuan Q,Xie J,He XM,Wang Q,Li JJ,Luo HR

更新日期：2019-06-18 00:00:00

abstract：:One function of glucocorticoids is to restore homeostasis after an acute stress response by providing negative feedback to stress circuits in the brain. Loss of this negative feedback leads to elevated physiological stress and may contribute to depression, anxiety, and post-traumatic stress disorder. We investigated t...

journal_title：Frontiers in behavioral neuroscience

authors： Griffiths BB,Schoonheim PJ,Ziv L,Voelker L,Baier H,Gahtan E

更新日期：2012-10-11 00:00:00

abstract：:Glutamatergic dysregulation is known to contribute to altered emotional regulation. Astrocytic glutamate transporter 1 (GLT1) is responsible for the majority of glutamate clearance from synapse. However, the role of astrocytic GLT1 in affective processes such as anxiety- and depression-like behavior is not fully under...

journal_title：Frontiers in behavioral neuroscience

authors： Jia YF,Wininger K,Ho AM,Peyton L,Baker M,Choi DS

更新日期：2020-04-22 00:00:00

abstract：:PAOPA, a potent analog of prolyl-leucyl-glycinamide, has shown therapeutic potential at the preclinical stage for dopaminergic related illnesses, including animal models of schizophrenia, Parkinson's disease and haloperidol-induced extrapyramidal movement disorders. PAOPA's unique allosteric mechanism and dopamine D2 ...

journal_title：Frontiers in behavioral neuroscience

authors： Daya RP,Bhandari J,Kooner SK,Ho J,Rowley CD,Bock NA,Farncombe T,Mishra RK

更新日期：2018-12-12 00:00:00

abstract：:Darwin (1872) postulated that emotional expressions contain universals that are retained across species. We recently showed that human rating responses were strongly affected by a listener's familiarity with vocalization types, whereas evidence for universal cross-taxa emotion recognition was limited. To disentangle t...

journal_title：Frontiers in behavioral neuroscience

authors： Scheumann M,Hasting AS,Zimmermann E,Kotz SA

更新日期：2017-10-24 00:00:00

abstract：:During perinatal life, sex steroids, such as estradiol, have marked effects on the development and function of the nervous system. Environmental estrogens or xenoestrogens are man-made chemicals, which animal and human population encounter in the environment and which are able to disrupt the functioning of the endocri...

journal_title：Frontiers in behavioral neuroscience

authors： Martini M,Calandreau L,Jouhanneau M,Mhaouty-Kodja S,Keller M

更新日期：2014-06-16 00:00:00

abstract：THIS STUDY HAD THE FOLLOWING TWO AIMS:First, to explore the effects of acute resistance exercise (RE, i.e., using exercise machines to contract and stretch muscles) on behavioral and electrophysiological performance when performing a cognitive task involving executive functioning in young male adults; Second, to invest...

journal_title：Frontiers in behavioral neuroscience

authors： Tsai CL,Wang CH,Pan CY,Chen FC,Huang TH,Chou FY

更新日期：2014-08-01 00:00:00

abstract：:Dysregulations in the brain serotonergic system and exposure to environmental stressors have been implicated in the development of major depressive disorder. Here, we investigate the interactions between the stress and serotonergic systems by characterizing the behavioral and biochemical effects of chronic stress appl...

journal_title：Frontiers in behavioral neuroscience

authors： Wong P,Sze Y,Gray LJ,Chang CC,Cai S,Zhang X

更新日期：2015-04-27 00:00:00

abstract：:Somatostatin (SOM) and somatostatin receptors (SSTR1-4) are present in all olfactory structures, including the olfactory bulb (OB), where SOM modulates physiological gamma rhythms and olfactory discrimination responses. In this work, histological, viral tracing and transgenic approaches were used to characterize SOM c...

journal_title：Frontiers in behavioral neuroscience

authors： Nocera S,Simon A,Fiquet O,Chen Y,Gascuel J,Datiche F,Schneider N,Epelbaum J,Viollet C

更新日期：2019-04-09 00:00:00

abstract：:The avoidance response is present in pathological anxiety and interferes with normal daily functions. The aim of this article is to shed light on performance markers of active avoidance (AA) using two different rat strains, Sprague-Dawley (SD) and Wistar. Specifically, good and poor performers were evaluated regarding...

journal_title：Frontiers in behavioral neuroscience

authors： de Oliveira CC,Gouveia FV,de Castro MC,Kuroki MA,Dos Santos LC,Fonoff ET,Teixeira MJ,Otoch JP,Martinez RC

更新日期：2016-08-24 00:00:00

abstract：Background:Brain investigations identified salience network (SN) comprising the dorsal Anterior Cingulate Cortex (dACC) and the Anterior Insula (AI). Magnetic resonance spectroscopy (MRS) studies revealed the link between the glutamate concentration in the ACC and alterations in attentional scope. Hence, we investigate...

journal_title：Frontiers in behavioral neuroscience

authors： von Düring F,Ristow I,Li M,Denzel D,Colic L,Demenescu LR,Li S,Borchardt V,Liebe T,Vogel M,Walter M

更新日期：2019-10-02 00:00:00

abstract：:Immediate early and constitutively expressed products of the Homer1 gene regulate the functional assembly of post-synaptic density proteins at glutamatergic synapses to influence excitatory neurotransmission and synaptic plasticity. Earlier studies of Homer1 gene knock-out (KO) mice indicated active, but distinct, rol...

journal_title：Frontiers in behavioral neuroscience

authors： Datko MC,Hu JH,Williams M,Reyes CM,Lominac KD,von Jonquieres G,Klugmann M,Worley PF,Szumlinski KK

更新日期：2017-11-01 00:00:00

abstract：:In humans, optimism is a cognitive construct related to motivation; optimists exert effort, whereas pessimists disengage from effort. In this study, using a recently developed ambiguous-cue interpretation (ACI) paradigm we took the unique opportunity to investigate whether "optimism" as a trait is correlated with moti...

journal_title：Frontiers in behavioral neuroscience

authors： Rygula R,Golebiowska J,Kregiel J,Kubik J,Popik P

更新日期：2015-02-25 00:00:00

abstract：:Over the last years, there has been a resurge in the interest to study the relationship between interoception and emotion. By now, it is well established that interoception contributes to the experience of emotions. However, it may also be possible that interoception contributes to the regulation of emotions. To test ...

journal_title：Frontiers in behavioral neuroscience

authors： Lischke A,Pahnke R,Mau-Moeller A,Jacksteit R,Weippert M

更新日期：2020-06-23 00:00:00

abstract：:Dscam2, a cell surface protein that mediates cellular repulsion, plays a crucial role in the development of the Drosophila melanogaster visual system. Dscam2 generates boundaries between neighboring modules in the fly optic lobe; in Dscam2 mutants this visual system modularity is compromised. Although developmental wi...

journal_title：Frontiers in behavioral neuroscience

authors： Bosch DS,van Swinderen B,Millard SS

更新日期：2015-06-09 00:00:00

abstract：:Evidence regarding the association between early drinking (ED) and later dependence is controversial. It has been alternately hypothesized that ED either plays a causal role in the development of dependence or that it is an early marker of increased psychosocial vulnerabilities. Despite a clear rationale for delaying ...

journal_title：Frontiers in behavioral neuroscience

authors： Conde K,Peltzer RI,Gimenez PV,Cremonte M

更新日期：2020-03-05 00:00:00

abstract：:As a model of anxiety disorder vulnerability, male Wistar-Kyoto (WKY) rats acquire lever-press avoidance behavior more readily than outbred Sprague-Dawley rats, and their acquisition is enhanced by the presence of a discrete signal presented during the inter-trial intervals (ITIs), suggesting that it is perceived as a...

journal_title：Frontiers in behavioral neuroscience

authors： Beck KD,Jiao X,Smith IM,Myers CE,Pang KC,Servatius RJ

更新日期：2014-11-21 00:00:00

abstract：:L-Kynurenine (L-KYN) is a central metabolite of tryptophan degradation through the kynurenine pathway (KP). The systemic administration of L-KYN sulfate (L-KYNs) leads to a rapid elevation of the neuroactive KP metabolite kynurenic acid (KYNA). An elevated level of KYNA may have multiple effects on the synaptic transm...

journal_title：Frontiers in behavioral neuroscience

authors： Varga D,Herédi J,Kánvási Z,Ruszka M,Kis Z,Ono E,Iwamori N,Iwamori T,Takakuwa H,Vécsei L,Toldi J,Gellért L

更新日期：2015-06-16 00:00:00

abstract：:DARPP-32 (PPP1R1B) was discovered as a substrate of cAMP-dependent protein kinase (PKA) enriched in dopamine-innervated brain areas. It is one of three related, PKA-regulated inhibitors of protein phosphatase-1 (PP1). These inhibitors seem to have appeared in early vertebrate ancestors, possibly Gnathostomes. DARPP-32...

journal_title：Frontiers in behavioral neuroscience

authors： Yger M,Girault JA

更新日期：2011-09-08 00:00:00

abstract：:Postpartum depression is a complex illness that often occurs in genetically predisposed individuals. Closely related inbred rat strains are a great resource to identify novel causative genes and mechanisms underlying complex traits such as postpartum behavior. We report differences in these behaviors between the inbre...

journal_title：Frontiers in behavioral neuroscience

authors： Luo W,Lim PH,Wert SL,Gacek SA,Chen H,Redei EE

更新日期：2020-10-22 00:00:00

abstract：:We study how the ratio between the length of the second and fourth digit (2D:4D) correlates with choices in social and risk preferences elicitation tasks by building a large dataset from five experimental projects with more than 800 subjects. Our results confirm the recent literature that downplays the link between 2D...

journal_title：Frontiers in behavioral neuroscience

authors： Alonso J,Di Paolo R,Ponti G,Sartarelli M

更新日期：2018-02-13 00:00:00

abstract：:An influential model suggests that dopamine signals the difference between predicted and experienced reward. In this way, dopamine can act as a learning signal that can shape behaviors to maximize rewards and avoid punishments. Dopamine is also thought to invigorate reward seeking behavior. Loss of dopamine signaling ...

journal_title：Frontiers in behavioral neuroscience

authors： Clark CA,Dagher A

更新日期：2014-05-30 00:00:00