Cardiac surgery in the elderly patient.

abstract：BACKGROUND:Participation rates in colorectal cancer screening in Germany are low. We therefore investigated the effectiveness of different invitation models for immunological stool blood tests (fecal immunological tests, FITs). METHODS:A randomized controlled trial in 50- to 54-year-old clients of the health insurance...

journal_title：Deutsches Arzteblatt international

authors： Gruner LF,Hoffmeister M,Ludwig L,Meny S,Brenner H

更新日期：2020-06-19 00:00:00

abstract：BACKGROUND:The German Standing Committee on Vaccination (STIKO) recommends vaccination against human papillomaviruses (HPV) of the high-risk types 16 and 18. The duration of protection afforded by HPV vaccines has been reported in multiple studies to date but has not been systematically evaluated. METHOD:Systematic li...

journal_title：Deutsches Arzteblatt international

authors： Deleré Y,Wichmann O,Klug SJ,van der Sande M,Terhardt M,Zepp F,Harder T

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Systematic reviews provide a structured summary of the results of trials that have been carried out on any particular subject. If the data from multiple trials are sufficiently homogenous, a meta-analysis can be performed to calculate pooled effect estimates. Traditional meta-analysis involves groups of tria...

journal_title：Deutsches Arzteblatt international

authors： Kiefer C,Sturtz S,Bender R

更新日期：2015-11-20 00:00:00

abstract：BACKGROUND:When reading reports of medical research findings, one is usually confronted with p-values. Publications typically contain not just one p-value, but an abundance of them, mostly accompanied by the word "significant." This article is intended to help readers understand the problem of multiple p-values and how...

journal_title：Deutsches Arzteblatt international

authors： Victor A,Elsässer A,Hommel G,Blettner M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The treatment of pregnant women who have illnesses unrelated to pregnancy can cause uncertainty among physicians. METHODS:We searched the PubMed database and specialty guidelines from Germany and abroad (the guidelines of the German Society for Gynecology and Obstetrics, the American Congress of Obstetri ci...

journal_title：Deutsches Arzteblatt international

authors： Bolz M,Körber S,Reimer T,Buchmann J,Schober HC,Briese V

更新日期：2017-09-15 00:00:00

abstract：BACKGROUND:Few reliable data are available on the epidemiology and treatment of spontaneous pneumothorax. We studied the sex and age distribution, frequency of hospitalization, mortality, and conservative versus surgical care of this condition in Germany in order to draw well-founded conclusions about its in-hospital d...

journal_title：Deutsches Arzteblatt international

authors： Schnell J,Koryllos A,Lopez-Pastorini A,Lefering R,Stoelben E

更新日期：2017-11-03 00:00:00

abstract：BACKGROUND:Patients with acquired brain injury who have been discharged from inpatient neurological rehabilitation often continue to suffer from limited independence, participation, and quality of life. Participation-focused outpatient treatment (in German: teilhabeorientierte ambulan. METHODS:In a randomized, control...

journal_title：Deutsches Arzteblatt international

authors： Bender A,Adrion C,Fischer L,Huber M,Jawny K,Straube A,Mansmann U

更新日期：2016-09-23 00:00:00

abstract：BACKGROUND:High-altitude travel, for mountain climbing, trekking, or sightseeing, has become very popular. Therefore, the awareness of its dangers has increased, and many prospective travelers seek medical advice before setting forth on their trip. METHODS:We selectively searched the literature for relevant original a...

journal_title：Deutsches Arzteblatt international

authors： Schommer K,Bärtsch P

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The neuropsychiatric symptoms of dementia, including aggressiveness, agitation, depression, and apathy are often treated with psychotropic drugs and are a frequent reason for hospitalization, placing an economic burden on the health care system. International guidelines recommend syndrome-specific pharmacoth...

journal_title：Deutsches Arzteblatt international

authors： Majic T,Pluta JP,Mell T,Aichberger MC,Treusch Y,Gutzmann H,Heinz A,Rapp MA

更新日期：2010-05-01 00:00:00

abstract：INTRODUCTION:The choice of type of heart valve prosthesis is determined by the patient's age since bioprostheses have a limited lifespan. This article reviews current recommendations and the literature on cardiac valve replacement. METHODS:Selective literature search in Medline/PubMed back to 1996 and review of curren...

journal_title：Deutsches Arzteblatt international

authors： Hoffmann G,Lutter G,Cremer J

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:Crohn's disease and ulcerative colitis are chronic inflammatory diseases resulting from an inappropriate immune response, in genetically susceptible individuals, to microbial antigens of commensal microorganisms. This inappropriate response is promoted by certain environmental factors. Both diseases manife...

journal_title：Deutsches Arzteblatt international

authors： Baumgart DC

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The long-term use of opioid analgesic drugs to treat chronic non-cancer pain (CNCP) is a major component of pain pharmacotherapy. The interpretation of the evidence concerning its efficacy and risks is currently debated. METHODS:An interdisciplinary evidence- and consensus-based S3 guideline was updated on ...

journal_title：Deutsches Arzteblatt international

authors： Häuser W,Bock F,Engeser P,Tölle T,Willweber-Strumpfe A,Petzke F

更新日期：2014-10-24 00:00:00

abstract：BACKGROUND:Avulsed frontal teeth often cannot be saved because of improper or lack of initial treatment. The result is a need for multiple interventions over the patient's lifetime, which also carry a high financial cost. METHODS:We explored the subject of lost anterior teeth in young patients with a PubMed search bas...

journal_title：Deutsches Arzteblatt international

authors： Brüllmann D,Schulze RK,d'Hoedt B

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The prevalence of abdominal aortic aneurysms (AAA) with a maximal diameter of 3 cm or more is age-dependent; among persons over age 65, it lies between 4% and 8% in men and between 0.5% and 1.5% in women. About 10% of all AAAs have a maximum diameter of 5 cm or more. The prognosis of ruptured AAA (rAAA) is d...

journal_title：Deutsches Arzteblatt international

authors： Eckstein HH,Böckler D,Flessenkämper I,Schmitz-Rixen T,Debus S,Lang W

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Adverse drug events (ADE) are a common cause of hospital admission as well as a common complication of inpatient care. The current reporting systems in Germany are of only limited use for the identification of ADE. The aim of this study is to examine the potential usefulness of ICD-10 coded diagnoses in rout...

journal_title：Deutsches Arzteblatt international

authors： Stausberg J,Hasford J

更新日期：2010-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.3238/arztebl.2017.0661.]. ...

journal_title：Deutsches Arzteblatt international

authors：

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The treatment of Hodgkin's disease (HD; also called Hodgkin's lymphoma) in children and adolescents with radiotherapy and chemotherapy leads to high survival rates but has a number of late effects. The most serious one is the development of a secondary malignant tumor, usually in the field that was irradiate...

journal_title：Deutsches Arzteblatt international

authors： Schellong G,Riepenhausen M,Ehlert K,Brämswig J,Dörffel W,German Working Group on the Long-Term Sequelae of Hodgkin's Disease.,Schmutzler RK,Rhiem K,Bick U,German Consortium for Hereditary Breast and Ovarian Cancer.

更新日期：2014-01-06 00:00:00

abstract：BACKGROUND:Some hematological malignancies arise in persons with a hereditary predisposition. The hereditary nature of these diseases often goes unrecognized, particularly when symptoms begin in adulthood. METHODS:This review is based on pertinent publications retrieved by a selective search in PubMed. RESULTS:Many r...

journal_title：Deutsches Arzteblatt international

authors： Bochtler T,Haag GM,Schott S,Kloor M,Krämer A,Müller-Tidow C

更新日期：2018-12-14 00:00:00

abstract：BACKGROUND:The diagnosis of soft-tissue sarcomas of the limbs is often delayed, sometimes markedly so, even though prompt and appropriate treatment improves survival and lowers the amputation rate. METHODS:On the basis of a selective literature review and consideration of the relevant guidelines, we developed an algor...

journal_title：Deutsches Arzteblatt international

authors： Bannasch H,Eisenhardt SU,Grosu AL,Heinz J,Momeni A,Stark GB

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Proper infant nutrition promotes healthy growth and development and lowers the risk of disease in later life. METHODS:This review is based on pertinent articles retrieved by a selective search, including guidelines, meta-analyses, and systematic reviews. RESULTS:Infants should be exclusively breast-fed unt...

journal_title：Deutsches Arzteblatt international

authors： Prell C,Koletzko B

更新日期：2016-06-24 00:00:00

abstract：BACKGROUND:Most women of child-bearing age want a safe method of contraception. Numerous methods are available, with different modes of application. In situations involving particular risks, the selection of the right method poses a special challenge. METHODS:Contraceptive methods for use in various situations with in...

journal_title：Deutsches Arzteblatt international

authors： Römer T

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:The past decade has seen much progress in intrauterine surgery. Randomized trials have documented the benefit of some procedures of this type for the unborn child. METHOD:Selective literature review RESULTS:Randomized trials have demonstrated the benefit of fetoscopic laser coagulation of placental anastom...

journal_title：Deutsches Arzteblatt international

authors： Diemert A,Diehl W,Glosemeyer P,Deprest J,Hecher K

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Isolated non-compaction cardiomyopathy (NCCM) was first described in 1984. This disorder, a primary genetic cardiomyopathy, is now attracting increased attention. METHOD:The current state of the epidemiology, pathogenesis, pathophysiology, clinical features, diagnosis, treatment, and prognosis of NCCM are d...

journal_title：Deutsches Arzteblatt international

authors： Engberding R,Stöllberger C,Ong P,Yelbuz TM,Gerecke BJ,Breithardt G

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:With improved cure rates of cancer in children and adolescents, the long-term effects of oncological treatment, including impaired fertility, have become an important clinical issue. METHODS:In 2008, we conducted a nationwide survey in Germany in which we asked 4689 female and male patients who had been tre...

journal_title：Deutsches Arzteblatt international

authors： Balcerek M,Reinmuth S,Hohmann C,Keil T,Borgmann-Staudt A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Women over age 65 with breast cancer are often not treated in accordance with current guidelines as far as adjuvant therapy is concerned, because of the lack of adequate scientific evidence. METHODS:This article is based on a selective review of pertinent literature retrieved by a PubMed search, as well as ...

journal_title：Deutsches Arzteblatt international

authors： Sautter-Bihl ML,Souchon R,Gerber B

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Atraumatic necrosis of the femoral head is a common cause of hip arthrosis in middle age. In Germany, it affects 5000-7000 patients per year, corresponding to an incidence of 0.01%. Though rarer than primary hip arthrosis, it is still of major clinical and socio-economic significance. Patients with this prob...

journal_title：Deutsches Arzteblatt international

authors： Arbab D,König DP

更新日期：2016-01-22 00:00:00

abstract：BACKGROUND:International studies show that aggressive behavior against primary care physicians is not an uncommon occurrence. There has been no systematic study to date of the nature and frequency of such occurrences in Germany. METHODS:A four-page questionnaire was sent to a nationwide random sample of 1500 primary c...

journal_title：Deutsches Arzteblatt international

authors： Vorderwülbecke F,Feistle M,Mehring M,Schneider A,Linde K

更新日期：2015-03-06 00:00:00

abstract：BACKGROUND:Acne is the most common skin disease in adolescence, with a prevalence of nearly 100%. About 60% of affected adolescents have mild acne for which they use non-prescription preparations without consulting a physician. The remaining 40% constitute the population of acne patients seen in medical practice. The c...

journal_title：Deutsches Arzteblatt international

authors： Gollnick HP,Zouboulis CC

更新日期：2014-04-25 00:00:00

abstract：BACKGROUND:Because of the changing dietary habits of an aging population, hyperuricemia is frequently found in combination with other metabolic disorders. Longstanding elevation of the serum uric acid level can lead to the deposition of monosodium urate crystals, causing gout (arthritis, urate nephropathy, tophi). In G...

journal_title：Deutsches Arzteblatt international

authors： Tausche AK,Jansen TL,Schröder HE,Bornstein SR,Aringer M,Müller-Ladner U

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Recent years have seen a further decline in the nationwide case fatality rate after major trauma in Germany, but it has not been clear until now whether all centers providing trauma care achieve comparable results. We have attempted to answer this question using data from the trauma registry of the German So...

journal_title：Deutsches Arzteblatt international

authors： Hilbert P,Lefering R,Stuttmann R

更新日期：2010-07-01 00:00:00