The Treatment of Illnesses Arising in Pregnancy.

abstract：BACKGROUND:Medication reviews and medication management are being used more and more around the world to improve medication safety. Both of these tools were originally conceived as pharmaceutical care activities and have recently been developed into interdisciplinary approaches. We studied the efficacy of interprofessi...

journal_title：Deutsches Arzteblatt international

authors： Köberlein-Neu J,Mennemann H,Hamacher S,Waltering I,Jaehde U,Schaffert C,Rose O

更新日期：2016-11-04 00:00:00

abstract：BACKGROUND:The N-methyl-D-aspartate (NMDA) antagonist dextromethorphan has been available in pharmacies without a prescription since 1954 as an antitussive agent. There is an alarming increase in reports of its abuse. Dextromethorphan is avidly taken, mainly by young people, as a psychoactive drug. The currently availa...

journal_title：Deutsches Arzteblatt international

authors： Mutschler J,Koopmann A,Grosshans M,Hermann D,Mann K,Kiefer F

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:In peripheral arterial occlusive disease (PAOD), arterial stenosis or occlusion impairs perfusion in the territory of the distal portion of the aorta and the iliac and leg arteries. In Germany, the prevalence of PAOD rises with age, reaching 20% among persons over age 70. METHODS:This guideline was prepared...

journal_title：Deutsches Arzteblatt international

authors： Lawall H,Huppert P,Espinola-Klein C,Rümenapf G

更新日期：2016-10-28 00:00:00

abstract：BACKGROUND:The estimated prevalence of fetal alcohol syndrome (FAS) is 8 for every 1000 live births. FAS has serious, lifelong consequences for the affected children and their families. A variety of professionals deal with persons who have FAS, including pediatricians, general practitioners, neurologists, gynecologists...

journal_title：Deutsches Arzteblatt international

authors： Landgraf MN,Nothacker M,Kopp IB,Heinen F

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Patients with acquired brain injury who have been discharged from inpatient neurological rehabilitation often continue to suffer from limited independence, participation, and quality of life. Participation-focused outpatient treatment (in German: teilhabeorientierte ambulan. METHODS:In a randomized, control...

journal_title：Deutsches Arzteblatt international

authors： Bender A,Adrion C,Fischer L,Huber M,Jawny K,Straube A,Mansmann U

更新日期：2016-09-23 00:00:00

abstract：BACKGROUND:High-altitude travel, for mountain climbing, trekking, or sightseeing, has become very popular. Therefore, the awareness of its dangers has increased, and many prospective travelers seek medical advice before setting forth on their trip. METHODS:We selectively searched the literature for relevant original a...

journal_title：Deutsches Arzteblatt international

authors： Schommer K,Bärtsch P

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Abdominal and thoracic aortic aneurysms are diagnosed in 40 and 10 to 15 out of 100 000 persons per year, respectively. Fenestrated (fEVAR) and branched (bEVAR) stent grafts have been developed for abdominal juxtarenal and thoracoabdominal aneurysms. We discuss the patency and complication rates of fEVAR and...

journal_title：Deutsches Arzteblatt international

authors： Rylski B,Czerny M,Südkamp M,Russe M,Siep M,Beyersdorf F

更新日期：2015-11-27 00:00:00

abstract：BACKGROUND:Direct (non-vitamin-K-dependent) oral anticoagulants (DOAC) are given as an alternative to vitamin K antagonists (VKA) to prevent stroke and embolic disease in patients with atrial fibrillation that is not due to pathology of the heart valves. Fatal hemorrhage is rarer when DOACs are given (nonvalvular atria...

journal_title：Deutsches Arzteblatt international

authors： Maegele M,Grottke O,Schöchl H,Sakowitz OA,Spannagl M,Koscielny J

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:Few reliable data are available on the epidemiology and treatment of spontaneous pneumothorax. We studied the sex and age distribution, frequency of hospitalization, mortality, and conservative versus surgical care of this condition in Germany in order to draw well-founded conclusions about its in-hospital d...

journal_title：Deutsches Arzteblatt international

authors： Schnell J,Koryllos A,Lopez-Pastorini A,Lefering R,Stoelben E

更新日期：2017-11-03 00:00:00

abstract：BACKGROUND:Because the course of Legg-Calvé-Perthes disease (LCPD) is highly variable, its appropriate diagnostic evaluation and treatment are still debated. METHODS:The authors selectively review the literature, present their own study findings, and discuss the guidelines of the German Society for Orthopedics and Ort...

journal_title：Deutsches Arzteblatt international

authors： Nelitz M,Lippacher S,Krauspe R,Reichel H

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Surgical site infections (SSI) are among the most common healthcare- associated infections. The aim of our explorative study was to determine how selected climatic factors are associated with SSI rates. METHODS:SSI rates were calculated for operative procedures included in the surgi- cal site infection surv...

journal_title：Deutsches Arzteblatt international

authors： Aghdassi SJS,Schwab F,Hoffmann P,Gastmeier P

更新日期：2019-08-05 00:00:00

abstract：BACKGROUND:The prevalence of abdominal aortic aneurysms (AAA) with a maximal diameter of 3 cm or more is age-dependent; among persons over age 65, it lies between 4% and 8% in men and between 0.5% and 1.5% in women. About 10% of all AAAs have a maximum diameter of 5 cm or more. The prognosis of ruptured AAA (rAAA) is d...

journal_title：Deutsches Arzteblatt international

authors： Eckstein HH,Böckler D,Flessenkämper I,Schmitz-Rixen T,Debus S,Lang W

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The conservative treatment of traumatic thoracolumbar vertebral fractures is often not clearly defined. METHODS:This review is based on articles retrieved by a systematic search in the PubMed and Web of Science databases for publications up to February 2018 dealing with the conservative treatment of traumat...

journal_title：Deutsches Arzteblatt international

authors： Spiegl UJ,Fischer K,Schmidt J,Schnoor J,Delank S,Josten C,Schulte T,Heyde CE

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:Nail disorders can arise at any age. About half of all nail disorders are of infectious origin, 15% are due to inflammatory or metabolic conditions, and 5% are due to malignancies and pigment disturbances. The differential diagnosis of nail disorders is often an area of uncertainty. METHODS:This review is b...

journal_title：Deutsches Arzteblatt international

authors： Wollina U,Nenoff P,Haroske G,Haenssle HA

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Infections with multidrug-resistant gram-negative bacteria are hard to treat and cause high morbidity and mortality. The direct transmission of such pathogens is well documented, and measures to protect other patients would seem indicated. Nonetheless, evidence-based recommendations are not yet available bec...

journal_title：Deutsches Arzteblatt international

authors： Mattner F,Bange FC,Meyer E,Seifert H,Wichelhaus TA,Chaberny IF

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Studies from multiple countries have shown that acute kidney injury (AKI) in hospitalized patients is associated with mortality and morbidity. There are no reliable data at present on the incidence and mortality of AKI episodes among hospitalized patients in Germany. The utility of administrative codings of ...

journal_title：Deutsches Arzteblatt international

authors： Khadzhynov D,Schmidt D,Hardt J,Rauch G,Gocke P,Eckardt KU,Schmidt-Ott KM

更新日期：2019-05-31 00:00:00

abstract：BACKGROUND:Multi-center observational studies in surgery can yield important findings, as long as they are appropriately designed and monitored and employ modern methods of statistical analysis. METHODS:In a multi-center quality assurance study carried out in 346 German hospitals from 2000 to 2004, data were collected...

journal_title：Deutsches Arzteblatt international

authors： Kube R,Gastinger I,Mroczkowski P,Ptok H,Wolff S,Lippert H

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The percentage of organ donors among the German population is very low, and the supply of organs does not meet the demand. Relatively few organ explantations are performed in Germany, compared to other countries. The central element leading up to organ explantation is the donor's consent. This can be express...

journal_title：Deutsches Arzteblatt international

authors： Küpers M,Dudda M,Kauther MD,Schwarz B,Hausen SA,Jöckel KH

更新日期：2020-03-13 00:00:00

abstract：BACKGROUND:5% to 8% of 70-year-olds and some 10% of persons over age 80 have atrial fibrillation (AF). METHODS:Selective literature review. RESULTS:New scoring schemes (CHA(2)DS(2)-VASc score, HAS-BLED score) have been introduced to enable more accurate estimation of the risk of stroke and hemorrhage in patients with...

journal_title：Deutsches Arzteblatt international

authors： Trappe HJ

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Epilepsy is the third most common disease affecting the brain in the elderly. Current demographic trends will lead to an increased prevalence of epilepsy in the general population. METHOD:A selective literature search revealed 102 relevant publications as of September 2008, 50 of which were original article...

journal_title：Deutsches Arzteblatt international

authors： Werhahn KJ

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Monoclonal antibodies (mAb) and fusion proteins (FP) are increasingly being used in children and adolescents. In this review, we analyze the evidence for their safety and efficacy in the treatment of the most common chronic inflammatory diseases. METHODS:We systematically searched PubMed, AWMF.org, and othe...

journal_title：Deutsches Arzteblatt international

authors： Niehues T,Özgür TT

更新日期：2019-10-18 00:00:00

abstract：BACKGROUND:As of 1 April 2007, pharmacists in Germany filling prescriptions covered by the statutory health insurance system (Gesetzliche Krankenversicherung, GKV) are required, whenever possible, to dispense a preparation that contains the same active substance and for which a rebate contract is in effect. The physici...

journal_title：Deutsches Arzteblatt international

authors： Hoffmann F,Glaeske G,Pfannkuche MS

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:The German Standing Committee on Vaccination Recommendations (Ständige Impfkommission, STIKO) recommends standard vaccination against pneumococcal infections for all persons aged 60 or older, and for all persons of any age with an increased health risk. It is not known how many persons in the target group in...

journal_title：Deutsches Arzteblatt international

authors： Theidel U,Kuhlmann A,Braem A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Urinary tract infections (UTI) are among the leading reasons for treatment in adult primary care medicine, accounting for a considerable percentage of antibiotic prescriptions. Because this problem is so common and so significant in routine clinical practice, a high level of diagnostic accuracy is essential....

journal_title：Deutsches Arzteblatt international

authors： Schmiemann G,Kniehl E,Gebhardt K,Matejczyk MM,Hummers-Pradier E

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:One-third of all patients with epilepsy have persistent seizures despite medical treatment. If the origin of the seizures can be localized to a particular site in the brain, epilepsy surgery is a treatment option that addresses the cause of the problem. METHOD:The presurgical assessment and surgical treatme...

journal_title：Deutsches Arzteblatt international

authors： Schulze-Bonhage A,Zentner J

更新日期：2014-05-02 00:00:00

abstract：BACKGROUND:When gunshot and blast injuries affect only a single person, first aid can always be delivered in conformity with the relevant guidelines. In contrast, when there is a dynamic casualty situation affecting many persons, such as after a terrorist attack, treatment may need to be focused on immediately life-thr...

journal_title：Deutsches Arzteblatt international

authors： Franke A,Bieler D,Friemert B,Schwab R,Kollig E,Güsgen C

更新日期：2017-04-07 00:00:00

abstract：BACKGROUND:Many patients in German hospitals complain of inadequate treatment of their postoperative pain. Hospital-related structural and procedural variables may affect pain perception and patient satisfaction. We studied the association of individual variables with outcome quality. METHODS:Data from the years 2011 ...

journal_title：Deutsches Arzteblatt international

authors： Meißner W,Komann M,Erlenwein J,Stamer U,Scherag A

更新日期：2017-03-10 00:00:00

abstract：BACKGROUND:With improved cure rates of cancer in children and adolescents, the long-term effects of oncological treatment, including impaired fertility, have become an important clinical issue. METHODS:In 2008, we conducted a nationwide survey in Germany in which we asked 4689 female and male patients who had been tre...

journal_title：Deutsches Arzteblatt international

authors： Balcerek M,Reinmuth S,Hohmann C,Keil T,Borgmann-Staudt A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:The long-term use of opioid analgesic drugs to treat chronic non-cancer pain (CNCP) is a major component of pain pharmacotherapy. The interpretation of the evidence concerning its efficacy and risks is currently debated. METHODS:An interdisciplinary evidence- and consensus-based S3 guideline was updated on ...

journal_title：Deutsches Arzteblatt international

authors： Häuser W,Bock F,Engeser P,Tölle T,Willweber-Strumpfe A,Petzke F

更新日期：2014-10-24 00:00:00

abstract：BACKGROUND:Treatment with checkpoint inhibitors such as anti-programmed death-1 (anti-PD-1), anti-PD-ligand 1 (anti-PD-L1), and anti-cytotoxic T-lymphocyte antigen-4 (anti-CTLA-4) antibodies can prolong the survival of cancer patients, but it also induces autoimmune side effects in 86-96% of patients by activating the ...

journal_title：Deutsches Arzteblatt international

authors： Heinzerling L,de Toni EN,Schett G,Hundorfean G,Zimmer L

更新日期：2019-02-22 00:00:00