The diagnosis and treatment of Crohn's disease and ulcerative colitis.

abstract：BACKGROUND:5% to 8% of 70-year-olds and some 10% of persons over age 80 have atrial fibrillation (AF). METHODS:Selective literature review. RESULTS:New scoring schemes (CHA(2)DS(2)-VASc score, HAS-BLED score) have been introduced to enable more accurate estimation of the risk of stroke and hemorrhage in patients with...

journal_title：Deutsches Arzteblatt international

authors： Trappe HJ

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Most women of child-bearing age want a safe method of contraception. Numerous methods are available, with different modes of application. In situations involving particular risks, the selection of the right method poses a special challenge. METHODS:Contraceptive methods for use in various situations with in...

journal_title：Deutsches Arzteblatt international

authors： Römer T

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:When gunshot and blast injuries affect only a single person, first aid can always be delivered in conformity with the relevant guidelines. In contrast, when there is a dynamic casualty situation affecting many persons, such as after a terrorist attack, treatment may need to be focused on immediately life-thr...

journal_title：Deutsches Arzteblatt international

authors： Franke A,Bieler D,Friemert B,Schwab R,Kollig E,Güsgen C

更新日期：2017-04-07 00:00:00

abstract：BACKGROUND:With improved cure rates of cancer in children and adolescents, the long-term effects of oncological treatment, including impaired fertility, have become an important clinical issue. METHODS:In 2008, we conducted a nationwide survey in Germany in which we asked 4689 female and male patients who had been tre...

journal_title：Deutsches Arzteblatt international

authors： Balcerek M,Reinmuth S,Hohmann C,Keil T,Borgmann-Staudt A

更新日期：2012-02-01 00:00:00

abstract：INTRODUCTION:This study analyzes the prevalence and associated factors for smoking and passive smoking among young people. METHODS:The data are derived from a subsample of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS), carried out by the Robert Koch Institute between May 2003 ...

journal_title：Deutsches Arzteblatt international

authors： Lampert T

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Studies from multiple countries have shown that acute kidney injury (AKI) in hospitalized patients is associated with mortality and morbidity. There are no reliable data at present on the incidence and mortality of AKI episodes among hospitalized patients in Germany. The utility of administrative codings of ...

journal_title：Deutsches Arzteblatt international

authors： Khadzhynov D,Schmidt D,Hardt J,Rauch G,Gocke P,Eckardt KU,Schmidt-Ott KM

更新日期：2019-05-31 00:00:00

abstract：BACKGROUND:The N-methyl-D-aspartate (NMDA) antagonist dextromethorphan has been available in pharmacies without a prescription since 1954 as an antitussive agent. There is an alarming increase in reports of its abuse. Dextromethorphan is avidly taken, mainly by young people, as a psychoactive drug. The currently availa...

journal_title：Deutsches Arzteblatt international

authors： Mutschler J,Koopmann A,Grosshans M,Hermann D,Mann K,Kiefer F

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Age-related macular degeneration (AMD) is a common retinal disease in older people. In Europe, about 1.6% of persons over age 65 and more than 13% of persons over age 85 have late-stage AMD, which can severely impair vision. The development of AMD is influenced both by environmental factors and by a strong h...

journal_title：Deutsches Arzteblatt international

authors： Weber BH,Charbel Issa P,Pauly D,Herrmann P,Grassmann F,Holz FG

更新日期：2014-02-21 00:00:00

abstract：BACKGROUND:The conservative treatment of traumatic thoracolumbar vertebral fractures is often not clearly defined. METHODS:This review is based on articles retrieved by a systematic search in the PubMed and Web of Science databases for publications up to February 2018 dealing with the conservative treatment of traumat...

journal_title：Deutsches Arzteblatt international

authors： Spiegl UJ,Fischer K,Schmidt J,Schnoor J,Delank S,Josten C,Schulte T,Heyde CE

更新日期：2018-10-19 00:00:00

abstract：BACKGROUND:Clostridium difficile infections are becoming more common, more severe, and more likely to recur. Conventional treatment with antibiotics often fails to eradicate the infection; even when it succeeds, recurrent infection is common. Complementary treatment with probiotic agents to reconstitute the physiologic...

journal_title：Deutsches Arzteblatt international

authors： Kleger A,Schnell J,Essig A,Wagner M,Bommer M,Seufferlein T,Härter G

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Abdominal and thoracic aortic aneurysms are diagnosed in 40 and 10 to 15 out of 100 000 persons per year, respectively. Fenestrated (fEVAR) and branched (bEVAR) stent grafts have been developed for abdominal juxtarenal and thoracoabdominal aneurysms. We discuss the patency and complication rates of fEVAR and...

journal_title：Deutsches Arzteblatt international

authors： Rylski B,Czerny M,Südkamp M,Russe M,Siep M,Beyersdorf F

更新日期：2015-11-27 00:00:00

abstract：INTRODUCTION:Many psychotropic drugs can delay cardiac repolarization and thereby prolong the rate-corrected QT interval (QTc). A prolonged QTc often arouses concern in clinical practice, as it can be followed, in rare cases, by the life-threatening polymorphic ventricular tachyarrhythmia called torsade de pointes (TdP...

journal_title：Deutsches Arzteblatt international

authors： Wenzel-Seifert K,Wittmann M,Haen E

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel diseases are common in Europe, with prevalences as high as 1 in 198 persons (ulcerative colitis) and 1 in 310 persons (Crohn's disease). METHODS:This review is based on pertinent articles retrieved by a search in PubMed and in German and European guidelines and Cochrane reviews of control...

journal_title：Deutsches Arzteblatt international

authors： Wehkamp J,Götz M,Herrlinger K,Steurer W,Stange EF

更新日期：2016-02-05 00:00:00

abstract：BACKGROUND:An estimated 1.4 to 2.6 million people in German suffer from drug dependence. Most of them are long-term users of benzodiazepines (BZD), Z drugs (ZD), or opioid analgesics (OA). METHODS:This analysis is based on prescription data from patients of the national statutory health insurance system in the German ...

journal_title：Deutsches Arzteblatt international

authors： Buth S,Holzbach R,Martens MS,Neumann-Runde E,Meiners O,Verthein U

更新日期：2019-09-13 00:00:00

abstract：BACKGROUND:Eliminating measles in Europe by 2015 is a WHO health goal. In Germany, physicians are legally required to report measles cases, yet it seems likely that reporting is less than universal. The goal of this study is to compare the number of measles cases that are reflected by data from the statutory health ins...

journal_title：Deutsches Arzteblatt international

authors： Mette A,Reuss AM,Feig M,Kappelmayer L,Siedler A,Eckmanns T,Poggensee G

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The German Federal Law on Radiation Control contains no special provisions for X-ray studies in children and adolescents, even though exposure to ionizing radiation must be kept especially low in young persons, because their tissues are highly radiosensitive. Children, who have many years left to live, are m...

journal_title：Deutsches Arzteblatt international

authors： Alzen G,Benz-Bohm G

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The randomized, controlled trial (RCT) is the gold standard of scientific evidence for the attribution of clinical effects (benefits and harms) to medical interventions. Many different designs for RCTs have been developed in order to counter legitimate critical objections and to better adapt the trials to th...

journal_title：Deutsches Arzteblatt international

authors： Lange S,Sauerland S,Lauterberg J,Windeler J

更新日期：2017-09-22 00:00:00

abstract：BACKGROUND:The long-term use of opioid analgesic drugs to treat chronic non-cancer pain (CNCP) is a major component of pain pharmacotherapy. The interpretation of the evidence concerning its efficacy and risks is currently debated. METHODS:An interdisciplinary evidence- and consensus-based S3 guideline was updated on ...

journal_title：Deutsches Arzteblatt international

authors： Häuser W,Bock F,Engeser P,Tölle T,Willweber-Strumpfe A,Petzke F

更新日期：2014-10-24 00:00:00

abstract：BACKGROUND:The many varieties of cystic pancreatic tumor, and especially intraductal papillary mucinous neoplasia (IPMN), have attracted increased attention recently. Their incidence may be rising, and their histopathological evaluation and classification have become more precise than before. METHODS:We discuss the cu...

journal_title：Deutsches Arzteblatt international

authors： Grützmann R,Post S,Saeger HD,Niedergethmann M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Sepsis, the most severe manifestation of acute infection, poses a major challenge to health care systems around the world. To date, adequate data on the incidence and mortality of sepsis in Germany have been lacking. METHODS:Nationwide case-related hospital DRG statistics for the years 2007-2013 were used t...

journal_title：Deutsches Arzteblatt international

authors： Fleischmann C,Thomas-Rueddel DO,Hartmann M,Hartog CS,Welte T,Heublein S,Dennler U,Reinhart K

更新日期：2016-03-11 00:00:00

abstract：BACKGROUND:The German Standing Committee on Vaccination (STIKO) recommends vaccination against human papillomaviruses (HPV) of the high-risk types 16 and 18. The duration of protection afforded by HPV vaccines has been reported in multiple studies to date but has not been systematically evaluated. METHOD:Systematic li...

journal_title：Deutsches Arzteblatt international

authors： Deleré Y,Wichmann O,Klug SJ,van der Sande M,Terhardt M,Zepp F,Harder T

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Current guidelines recommend using aspirin, clopidogrel, beta-blockers, statins, and angiotensin converting enzyme (ACE) inhibitors after acute myocardial infarction (AMI). Although there is evidence that patients often stop taking these medications prematurely, long-term data reflecting the actual reality o...

journal_title：Deutsches Arzteblatt international

authors： Mangiapane S,Busse R

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The German Standing Committee on Vaccination Recommendations (Ständige Impfkommission, STIKO) recommends standard vaccination against pneumococcal infections for all persons aged 60 or older, and for all persons of any age with an increased health risk. It is not known how many persons in the target group in...

journal_title：Deutsches Arzteblatt international

authors： Theidel U,Kuhlmann A,Braem A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Although the number of elderly patients with fractures is increasing, there have been only a few studies to date of the efficacy of collaborative treatment by trauma surgeons and geriatricians. METHODS:Data on patients over age 75 with femoral neck, trochanteric, proximal humeral, and pelvic ring fractures ...

journal_title：Deutsches Arzteblatt international

authors： Grund S,Roos M,Duchene W,Schuler M

更新日期：2015-02-13 00:00:00

abstract：BACKGROUND:Pulsatile tinnitus, unlike idiopathic tinnitus, usually has a specific, identifiable cause. Nonetheless, uncertainty often arises in clinical practice about the findings to be sought and the strategy for work-up. METHODS:Selective literature review and evaluation of our own series of patients. RESULTS:Puls...

journal_title：Deutsches Arzteblatt international

authors： Hofmann E,Behr R,Neumann-Haefelin T,Schwager K

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Some hematological malignancies arise in persons with a hereditary predisposition. The hereditary nature of these diseases often goes unrecognized, particularly when symptoms begin in adulthood. METHODS:This review is based on pertinent publications retrieved by a selective search in PubMed. RESULTS:Many r...

journal_title：Deutsches Arzteblatt international

authors： Bochtler T,Haag GM,Schott S,Kloor M,Krämer A,Müller-Tidow C

更新日期：2018-12-14 00:00:00

abstract：INTRODUCTION:Military missions abroad carry a high risk of psychological traumatization. In this study, we examined the reasons for increased utilization of the treatments offered to soldiers by the German armed forces' psychiatric services. METHOD:We analyzed trends in initial contacts with psychiatrists and psychoth...

journal_title：Deutsches Arzteblatt international

authors： Kowalski JT,Hauffa R,Jacobs H,Höllmer H,Gerber WD,Zimmermann P

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Sunlight induces a wide variety of dermatoses. Their differential diagnosis is problematic not only because of similar phenotypes, but also because of confusing nomenclature and classification. METHODS:We selectively reviewed the literature of the past 20 years and describe the modern nosology of photoderma...

journal_title：Deutsches Arzteblatt international

authors： Lehmann P,Schwarz T

更新日期：2011-03-01 00:00:00

abstract：INTRODUCTION:Autopsy studies of persons who died of cancer have shown the lungs to be the sole site of metastasis in about 20% of cases. The resection of pulmonary metastases is indicated for palliative purposes if they contain a large volume of necrotic tumor, infiltrate the thoracic wall to produce pain, or cause hem...

journal_title：Deutsches Arzteblatt international

authors： Pfannschmidt J,Egerer G,Bischof M,Thomas M,Dienemann H

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Cerebral amyloid angiopathy (CAA) is a degenerative vasculopathy that is classically associated with lobar intracerebral or sulcal hemorrhage. Its prevalence is estimated at 30% in the seventh decade and 50% in the eighth and ninth decades. In this review, we summarize the risks linked to CAA with respect to...

journal_title：Deutsches Arzteblatt international

authors： Block F,Dafotakis M

更新日期：2017-01-20 00:00:00