Gout--current diagnosis and treatment.

abstract：BACKGROUND:Acne is the most common skin disease in adolescence, with a prevalence of nearly 100%. About 60% of affected adolescents have mild acne for which they use non-prescription preparations without consulting a physician. The remaining 40% constitute the population of acne patients seen in medical practice. The c...

journal_title：Deutsches Arzteblatt international

authors： Gollnick HP,Zouboulis CC

更新日期：2014-04-25 00:00:00

abstract：BACKGROUND:Optimizing the emergency medical care chain might shorten the time to treatment of patients with ST-elevation myocardial infarction (STEMI). The initial care by a physician, and, in particular, correct ECG interpretation, are critically important factors. METHODS:From 1999 onward, data on the care of patien...

journal_title：Deutsches Arzteblatt international

authors： Stockburger M,Maier B,Fröhlich G,Rutsch W,Behrens S,Schoeller R,Theres H,Poloczek S,Plock G,Schühlen H

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Avulsed frontal teeth often cannot be saved because of improper or lack of initial treatment. The result is a need for multiple interventions over the patient's lifetime, which also carry a high financial cost. METHODS:We explored the subject of lost anterior teeth in young patients with a PubMed search bas...

journal_title：Deutsches Arzteblatt international

authors： Brüllmann D,Schulze RK,d'Hoedt B

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:When reading reports of medical research findings, one is usually confronted with p-values. Publications typically contain not just one p-value, but an abundance of them, mostly accompanied by the word "significant." This article is intended to help readers understand the problem of multiple p-values and how...

journal_title：Deutsches Arzteblatt international

authors： Victor A,Elsässer A,Hommel G,Blettner M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The treatment of pregnant women who have illnesses unrelated to pregnancy can cause uncertainty among physicians. METHODS:We searched the PubMed database and specialty guidelines from Germany and abroad (the guidelines of the German Society for Gynecology and Obstetrics, the American Congress of Obstetri ci...

journal_title：Deutsches Arzteblatt international

authors： Bolz M,Körber S,Reimer T,Buchmann J,Schober HC,Briese V

更新日期：2017-09-15 00:00:00

abstract：BACKGROUND:Patients with ovarian cancer usually present to a family physician with nonspecific symptoms, most often abdominal pain. The outcome depends above all on the stage of the disease when it is diagnosed and on the quality of treatment. METHODS:This article is based on a review of selected publications from 200...

journal_title：Deutsches Arzteblatt international

authors： Burges A,Schmalfeldt B

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The effectiveness of intraoral appliances (IOA), maxillary expansion (ME), and maxillomandibular advancement (MMA) in the treatment of children and adults with obstructive sleep apnea (OSA) has not yet been adequately assessed. METHODS:An umbrella review was performed based on established guidelines for evi...

journal_title：Deutsches Arzteblatt international

authors： Koretsi V,Eliades T,Papageorgiou SN

更新日期：2018-03-23 00:00:00

abstract：BACKGROUND:As of 1 April 2007, pharmacists in Germany filling prescriptions covered by the statutory health insurance system (Gesetzliche Krankenversicherung, GKV) are required, whenever possible, to dispense a preparation that contains the same active substance and for which a rebate contract is in effect. The physici...

journal_title：Deutsches Arzteblatt international

authors： Hoffmann F,Glaeske G,Pfannkuche MS

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Medication reviews and medication management are being used more and more around the world to improve medication safety. Both of these tools were originally conceived as pharmaceutical care activities and have recently been developed into interdisciplinary approaches. We studied the efficacy of interprofessi...

journal_title：Deutsches Arzteblatt international

authors： Köberlein-Neu J,Mennemann H,Hamacher S,Waltering I,Jaehde U,Schaffert C,Rose O

更新日期：2016-11-04 00:00:00

abstract：BACKGROUND:Overweight and obesity are generally thought to elevate morbidity and mortality. New data call this supposed association into question. METHODS:The Cochrane, Pubmed, and other databases were systematically searched for a combination of relevant terms and subject headings. Meta-analyses and cohort studies ba...

journal_title：Deutsches Arzteblatt international

authors： Lenz M,Richter T,Mühlhauser I

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:One-third of all patients with epilepsy have persistent seizures despite medical treatment. If the origin of the seizures can be localized to a particular site in the brain, epilepsy surgery is a treatment option that addresses the cause of the problem. METHOD:The presurgical assessment and surgical treatme...

journal_title：Deutsches Arzteblatt international

authors： Schulze-Bonhage A,Zentner J

更新日期：2014-05-02 00:00:00

abstract：BACKGROUND:Epilepsy is the third most common disease affecting the brain in the elderly. Current demographic trends will lead to an increased prevalence of epilepsy in the general population. METHOD:A selective literature search revealed 102 relevant publications as of September 2008, 50 of which were original article...

journal_title：Deutsches Arzteblatt international

authors： Werhahn KJ

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:When gunshot and blast injuries affect only a single person, first aid can always be delivered in conformity with the relevant guidelines. In contrast, when there is a dynamic casualty situation affecting many persons, such as after a terrorist attack, treatment may need to be focused on immediately life-thr...

journal_title：Deutsches Arzteblatt international

authors： Franke A,Bieler D,Friemert B,Schwab R,Kollig E,Güsgen C

更新日期：2017-04-07 00:00:00

abstract：BACKGROUND:Recent years have seen a further decline in the nationwide case fatality rate after major trauma in Germany, but it has not been clear until now whether all centers providing trauma care achieve comparable results. We have attempted to answer this question using data from the trauma registry of the German So...

journal_title：Deutsches Arzteblatt international

authors： Hilbert P,Lefering R,Stuttmann R

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The diagnosis of soft-tissue sarcomas of the limbs is often delayed, sometimes markedly so, even though prompt and appropriate treatment improves survival and lowers the amputation rate. METHODS:On the basis of a selective literature review and consideration of the relevant guidelines, we developed an algor...

journal_title：Deutsches Arzteblatt international

authors： Bannasch H,Eisenhardt SU,Grosu AL,Heinz J,Momeni A,Stark GB

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Nail disorders can arise at any age. About half of all nail disorders are of infectious origin, 15% are due to inflammatory or metabolic conditions, and 5% are due to malignancies and pigment disturbances. The differential diagnosis of nail disorders is often an area of uncertainty. METHODS:This review is b...

journal_title：Deutsches Arzteblatt international

authors： Wollina U,Nenoff P,Haroske G,Haenssle HA

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Cluster-randomized trials (CRT) are needed to compare interventions that are allocated to entire groups of subjects, rather than to individuals. Publications about CRT have become steadily more common over the past decade. Readers of such publications should be able to categorize and interpret the findings o...

journal_title：Deutsches Arzteblatt international

authors： Lorenz E,Köpke S,Pfaff H,Blettner M

更新日期：2018-03-09 00:00:00

abstract：BACKGROUND:The prevalence of latent/subclinical hypothyroidism is between 3% and 10%, according to epidemiologic studies that have been carried out in the USA, the United Kingdom, and Denmark. As persons with latent hypo - thyroidism are often asymptomatic, the diagnosis is often made incidentally in routine laboratory...

journal_title：Deutsches Arzteblatt international

authors： Schübel J,Feldkamp J,Bergmann A,Drossard W,Voigt K

更新日期：2017-06-23 00:00:00

abstract：BACKGROUND:The histomorphological changes of lung damage in severe coronavirus disease 2019 (COVID-19) have not yet been adequately characterized. In this article, we describe the sequence of pathological changes in COVID-19 and discuss the implications for approaches to treatment. METHODS:Standardized autopsies were ...

journal_title：Deutsches Arzteblatt international

authors： Kommoss FKF,Schwab C,Tavernar L,Schreck J,Wagner WL,Merle U,Jonigk D,Schirmacher P,Longerich T

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:In this study, we investigated the measures currently being taken in German hospitals to prevent infection with methicillin-resistant strains of Staphylococcus aureus (MRSA). To this end, we circulated a questionnaire among hospitals participating in the MRSA-KISS module. "KISS" in the name of this project s...

journal_title：Deutsches Arzteblatt international

authors： Chaberny IF,Wriggers A,Behnke M,Gastmeier P

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Participation rates in colorectal cancer screening in Germany are low. We therefore investigated the effectiveness of different invitation models for immunological stool blood tests (fecal immunological tests, FITs). METHODS:A randomized controlled trial in 50- to 54-year-old clients of the health insurance...

journal_title：Deutsches Arzteblatt international

authors： Gruner LF,Hoffmeister M,Ludwig L,Meny S,Brenner H

更新日期：2020-06-19 00:00:00

abstract：BACKGROUND:Early gastro-esophageal cancer is staged as m1 to m3 depending on the infiltration of the anatomical layers of the mucosa or, analogously, as sm1 to sm3 depending on the depth of infiltration into the submucosa. The risk of lymph node metastases is low in mucosal carcinoma but increases with the depth of inf...

journal_title：Deutsches Arzteblatt international

authors： Gockel I,Hoffmeister A

更新日期：2018-08-06 00:00:00

abstract：BACKGROUND:Pilonidal disease is an acute or chronic infection in the subcutaneous fatty tissue, mainly in the natal cleft. Its incidence in Germany in 2012 was 48 cases per 100 000 persons per year. METHODS:This review is based on pertinent publications retrieved by a selective literature search. RESULTS:The numerous...

journal_title：Deutsches Arzteblatt international

authors： Iesalnieks I,Ommer A

更新日期：2019-01-07 00:00:00

abstract：BACKGROUND:The percentage of organ donors among the German population is very low, and the supply of organs does not meet the demand. Relatively few organ explantations are performed in Germany, compared to other countries. The central element leading up to organ explantation is the donor's consent. This can be express...

journal_title：Deutsches Arzteblatt international

authors： Küpers M,Dudda M,Kauther MD,Schwarz B,Hausen SA,Jöckel KH

更新日期：2020-03-13 00:00:00

abstract：BACKGROUND:Systematic reviews provide a structured summary of the results of trials that have been carried out on any particular subject. If the data from multiple trials are sufficiently homogenous, a meta-analysis can be performed to calculate pooled effect estimates. Traditional meta-analysis involves groups of tria...

journal_title：Deutsches Arzteblatt international

authors： Kiefer C,Sturtz S,Bender R

更新日期：2015-11-20 00:00:00

abstract：BACKGROUND:25% of all women report involuntary loss of urine, and 7% may require treatment. METHODS:This review is based on a selection of pertinent literature, including guidelines and Cochrane reviews. RESULTS:The assessment of pelvic floor dysfunction in women begins with a basic evaluation that is followed by spe...

journal_title：Deutsches Arzteblatt international

authors： Jundt K,Peschers U,Kentenich H

更新日期：2015-08-17 00:00:00

abstract：BACKGROUND:Recent years have seen major changes in the diagnosis and treatment of solid intraocular tumors, mainly owing to an improved molecular biological understanding of their pathogenesis, new therapeutic approaches for the local treatment of tumors in children, and long-term follow-up observations in clinical tri...

journal_title：Deutsches Arzteblatt international

authors： Bornfeld N,Biewald E,Bauer S,Temming P,Lohmann D,Zeschnigk M

更新日期：2018-02-16 00:00:00

abstract：BACKGROUND:The incidence of sudden cardiac death in persons under age 40 is roughly 3 per 100 000 persons per year in Germany and North America. Many of these deaths are found to be due to hereditary heart diseases, often a primary structural heart disease associated with arrhythmia or else a primary arrhythmia syndrom...

journal_title：Deutsches Arzteblatt international

authors： Beckmann BM,Pfeufer A,Kääb S

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Clinical guidelines recommend psychosocial care as an integral part of medical treatment, but access is often limited. Technology-based approaches provide an attractive opportunity to optimize health outcomes and quality of life in people with chronic somatic diseases e.g. by means of Internet- and mobile-ba...

journal_title：Deutsches Arzteblatt international

authors： Bendig E,Bauereiß N,Ebert DD,Snoek F,Andersson G,Baumeister H

更新日期：2018-11-05 00:00:00

abstract：INTRODUCTION:The range of indications for vitreoretinal surgery has widened in recent years, and intraocular gas application is frequently performed as part of retinal surgery, with the aim of achieving long-acting tamponade. METHODS:Selective literature review. RESULTS:An intraocular gas bubble containing perfluorop...

journal_title：Deutsches Arzteblatt international

authors： Silvanus MT,Moldzio P,Bornfeld N,Peters J

更新日期：2008-02-01 00:00:00