Effects of chronic exposure of hydroxychloroquine/chloroquine on the risk of cancer, metastasis, and death: a population-based cohort study on patients with connective tissue diseases.

abstract：BACKGROUND:Primary hyperparathyroidism (pHPT) is associated with an increased risk of developing breast cancer, but little is known about the underlying factors. The aim of this study was to compare women with a history of pHPT and a reference population in terms of standard factors predictive of prognosis and response...

journal_title：Clinical epidemiology

authors： Norenstedt S,Granath F,Ekbom A,Bergh J,Lambe M,Adolfsson J,Warnberg F,Zedenius J,Nilsson IL

更新日期：2011-03-25 00:00:00

abstract：:Sjögren's syndrome is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands. It can present as an entity by itself, primary Sjögren's syndrome (pSS), or in addition to another autoimmune disease, secondary Sjögren's syndrome (sSS). pSS has a strong female propensity and is ...

journal_title：Clinical epidemiology

authors： Patel R,Shahane A

更新日期：2014-07-30 00:00:00

abstract：:Memory diseases are the most important determinant of health care service use and quality of life among older individuals. Adverse effects of medication are common among older people, but this age group is underrepresented in clinical trials. Finnish statutory health care and prescription registers, together with pers...

journal_title：Clinical epidemiology

authors： Tolppanen AM,Taipale H,Koponen M,Lavikainen P,Tanskanen A,Tiihonen J,Hartikainen S

更新日期：2013-08-07 00:00:00

abstract：Background:The combination of organized cervical cancer screening and childhood HPV vaccination programs has the potential to eliminate cervical cancer in the future. However, only women participating in both programs gain the full protection, and combined non-attenders remain at high risk of developing cervical cancer...

journal_title：Clinical epidemiology

authors： Badre-Esfahani S,Larsen MB,Seibæk L,Petersen LK,Blaakær J,Støvring H,Andersen B

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:Administrative data may be useful for epidemiological studies of chronic idiopathic thrombocytopenic purpura (ITP). However, the quality of the recorded diagnoses needs evaluation. AIM:We evaluated the validity in predicting chronic ITP of the International Classification of Diseases (ICD)-10 diagnoses of I...

journal_title：Clinical epidemiology

authors： Heden KE,Jensen AØ,Farkas DK,Nørgaard M

更新日期：2009-08-09 00:00:00

abstract：Purpose:To validate the use of International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes to identify patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in the Taiwan National Health Insurance (NHI) Outpatient Claims Dataset. Methods:We conducted ...

journal_title：Clinical epidemiology

authors： Sheu MJ,Liang FW,Li ST,Li CY,Lu TH

更新日期：2020-02-20 00:00:00

abstract：Background:Previous studies have shown a link between increased dietary intake of arachidonic acid (ARA) and colorectal neoplasms. It has been shown that erythrocyte phospholipid membrane concentrations of ARA are strongly determined by genetic variation. Fatty acid desaturase (FADS) controls the rate limiting step in ...

journal_title：Clinical epidemiology

authors： Isom CA,Shrubsole MJ,Cai Q,Smalley WE,Ness RM,Zheng W,Murff HJ

更新日期：2018-12-18 00:00:00

abstract：OBJECTIVE:We examined the association between lifestyle factors and menstrual cycle characteristics among nulliparous Danish women aged 18-40 years who were participating in an Internet-based prospective cohort study of pregnancy planners. METHODS:We used cross-sectional data collected at baseline to assess the associ...

journal_title：Clinical epidemiology

authors： Hahn KA,Wise LA,Riis AH,Mikkelsen EM,Rothman KJ,Banholzer K,Hatch EE

更新日期：2013-08-19 00:00:00

abstract：BACKGROUND:Severe infection resulting in sepsis is recognized as a leading cause of morbidity and mortality worldwide. The purpose of this study is to use longitudinal, population-based data to report national-level hospital metrics, providing a current assessment of the status of sepsis hospitalizations in Canadian ch...

journal_title：Clinical epidemiology

authors： Thompson GC,Kissoon N

更新日期：2014-12-05 00:00:00

abstract：OBJECTIVES:Translational epidemiology studies often use archived tumor specimens to evaluate genetic hypotheses involving cancer outcomes. When the exposure of interest is a germline polymorphism, a key concern is whether the genotype assayed from tumor-derived DNA is representative of the germline. We evaluated the co...

journal_title：Clinical epidemiology

authors： Ahern TP,Christensen M,Cronin-Fenton DP,Lunetta KL,Rosenberg CL,Sørensen HT,Lash TL,Hamilton-Dutoit S

更新日期：2010-10-22 00:00:00

abstract：Purpose:Inherited ichthyosis is a monogenetic disease characterized by hyperkeratosis and scaling of the skin, with large interindividual variation in severity. It can affect quality of life for patients and their families. Population-based data on inherited ichthyosis are lacking, which hampers studies into its epidem...

journal_title：Clinical epidemiology

authors： Kristensen MH,Schmidt SAJ,Kibsgaard L,Hove H,Sommerlund M,Koppelhus U

更新日期：2020-06-19 00:00:00

abstract：Background:In 2012, liver cancer ranked as the fifth and eighth most common cancer in men and women, respectively, in urban Shanghai. This study aims to present the trend and projection of age-specific incidence and mortality of liver cancer in Shanghai. Methods:We extracted data of liver cancer incident cases and dea...

journal_title：Clinical epidemiology

authors： Bai L,Liu Z,Fang Q,Yan Q,Shi O,Bao P,Mu L,Chen X,Zhang T

更新日期：2018-03-09 00:00:00

abstract：Objective:Reports on the epidemiology of vestibular schwannoma (VS) indicate an increase in diagnosed cases, often based on selected materials over a limited period of time. This report presents prospective 40-year epidemiological data from an unselected national cohort of all patients diagnosed with a VS in Denmark si...

journal_title：Clinical epidemiology

authors： Reznitsky M,Petersen MMBS,West N,Stangerup SE,Cayé-Thomasen P

更新日期：2019-11-08 00:00:00

abstract：Purpose:This paper aims to compare the clinical effectiveness of oral anti-osteoporosis drugs based on the observed risk of fracture while on treatment in primary care actual practice. Materials and methods:We investigated two primary care records databases covering UK National Health Service (Clinical Practice Resear...

journal_title：Clinical epidemiology

authors： Khalid S,Calderon-Larrañaga S,Hawley S,Ali MS,Judge A,Arden N,van Staa T,Cooper C,Javaid MK,Prieto-Alhambra D

更新日期：2018-10-09 00:00:00

abstract：:Characterizing the relations between exposures and diseases is the central tenet of epidemiology. Researchers may want to evaluate exposure-disease causation by assessing whether the disease under concern is induced by the various exposures - the so-called "attribution". In this paper, the authors propose a method to ...

journal_title：Clinical epidemiology

authors： Chen C,Lee WC

更新日期：2018-04-27 00:00:00

abstract：BACKGROUND:A number of population-based studies have demonstrated lower cancer survival in elderly patients than among middle-aged or younger patients. Also, data quality in cancer registries has been shown to be associated with age. The objective of this study was to examine the recent age-specific cancer survival tre...

journal_title：Clinical epidemiology

authors： Innos K,Lang K,Pärna K,Aareleid T

更新日期：2015-07-29 00:00:00

abstract：:When healthcare professionals have the choice between several drug treatments for their patients, they often experience considerable decision uncertainty because many decisions simply have no single "best" choice. The challenges are manifold and include that guideline recommendations focus on randomized controlled tri...

journal_title：Clinical epidemiology

authors： Meid AD,Ruff C,Wirbka L,Stoll F,Seidling HM,Groll A,Haefeli WE

更新日期：2020-11-02 00:00:00

abstract：Aim:To improve consistency between register studies in Sweden and ensure valid comparisons of possible changes in alcohol-related disorders and diseases (ARDDs) over time, we propose a definition of ARDDs. Based on this definition, we examined Sweden's incidence rates of ARDDs from 1970 to 2018 in non-primary healthcar...

journal_title：Clinical epidemiology

authors： Bergman D,Hagström H,Capusan AJ,Mårild K,Nyberg F,Sundquist K,Ludvigsson JF

更新日期：2020-12-31 00:00:00

abstract：Purpose:To develop a self-administered diagnostic screening questionnaire for lumbar spinal stenosis (LSS) consisting of items with high content validity and to investigate the diagnostic value of the questionnaire and the items. Patients and Methods:A self-reported diagnostic LSS screening questionnaire was developed...

journal_title：Clinical epidemiology

authors： Jensen RK,Lauridsen HH,Andresen ADK,Mieritz RM,Schiøttz-Christensen B,Vach W

更新日期：2020-08-19 00:00:00

abstract：Background:Participation in cervical cancer screening varies by socioeconomic status. The aims were to assess if offering human papilloma virus (HPV) self-sampling kits has an effect on screening participation among various socioeconomic groups and to determine if two invitation strategies for offering self-sampling in...

journal_title：Clinical epidemiology

authors： Tranberg M,Bech BH,Blaakær J,Jensen JS,Svanholm H,Andersen B

更新日期：2018-08-23 00:00:00

abstract：:The Danish health care system provides partial reimbursement of most prescription medications in Denmark. The dispensation of prescription medications is registered in administrative databases. Each time a prescription is redeemed at a pharmacy, an electronic record is generated with information related to the user, p...

journal_title：Clinical epidemiology

authors： Johannesdottir SA,Horváth-Puhó E,Ehrenstein V,Schmidt M,Pedersen L,Sørensen HT

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to validate the data in the Aarhus Sarcoma Registry (ASR), to determine if this registry is population-based for western Denmark, and to examine the incidence of sarcomas using validated, population-based registry data. METHODS:This study was based on patients with bone and ...

journal_title：Clinical epidemiology

authors： Maretty-Nielsen K,Aggerholm-Pedersen N,Keller J,Safwat A,Baerentzen S,Pedersen AB

更新日期：2013-03-06 00:00:00

abstract：Purpose:Comorbidity indices are often used to measure comorbidities in register-based research. We aimed to adapt the Charlson comorbidity index (CCI) to a Swedish setting. Methods:Four versions of the CCI were compared and evaluated by disease-specific experts. Results:We created a cohesive coding system for CCI to ...

journal_title：Clinical epidemiology

authors： Ludvigsson JF,Appelros P,Askling J,Byberg L,Carrero JJ,Ekström AM,Ekström M,Smedby KE,Hagström H,James S,Järvholm B,Michaelsson K,Pedersen NL,Sundelin H,Sundquist K,Sundström J

更新日期：2021-01-12 00:00:00

abstract：Background:Primary care databases represent a rich source of data for health care research; however, the quality of recording of secondary care events in these databases is uncertain. This study sought to investigate the completeness of recording of hospital admissions for bleeds in primary care records and explore the...

journal_title：Clinical epidemiology

authors： McDonald L,Sammon CJ,Samnaliev M,Ramagopalan S

更新日期：2018-09-04 00:00:00

abstract：:The management of brain-dead organ donors is complex. The use of inotropic agents and replacement of depleted hormones (hormonal replacement therapy) is crucial for successful multiple organ procurement, yet the optimal hormonal replacement has not been identified, and the statistical adjustment to determine the best ...

journal_title：Clinical epidemiology

authors： Mi Z,Novitzky D,Collins JF,Cooper DK

更新日期：2014-12-22 00:00:00

abstract：:Introduction: Spontaneous (non-traumatic) subarachnoid hemorrhage (ntSAH) is frequently suspected in the emergency department, but the incidence rate is low. Diagnosis registers can provide valuable data for research in uncommon conditions like ntSAH. Unfortunately, validity vary in the registers. We aimed to assess t...

journal_title：Clinical epidemiology

authors： Sonne A,Andersen JB,Rasmussen LS

更新日期：2019-05-01 00:00:00

abstract：Background:Cost-effective primary prevention of cardiovascular disease (CVD) relies on accuracy of risk assessment. Current risk scores require clinical and laboratory measures, are expensive and are often difficult to apply in the population setting. Objective:This study sought to estimate CVD risk from individuals' ...

journal_title：Clinical epidemiology

authors： Duval S,Van't Hof JR,Steffen LM,Luepker RV

更新日期：2020-01-14 00:00:00

abstract：:Routinely-collected health data (RCD) are now used for a wide range of studies, including observational studies, comparative effectiveness research, diagnostics, studies of adverse effects, and predictive analytics. At the same time, limitations inherent in using data collected without specific a priori research quest...

journal_title：Clinical epidemiology

authors： Nicholls SG,Langan SM,Sørensen HT,Petersen I,Benchimol EI

更新日期：2016-10-19 00:00:00

abstract：Background:The presence of comorbid medical conditions can significantly affect a cancer patient's treatment options, quality of life, and survival. However, these important data are often lacking from population-based cancer registries. Leveraging routine linkage to hospital discharge data, a comorbidity score was cal...

journal_title：Clinical epidemiology

authors： Lichtensztajn DY,Giddings BM,Morris CR,Parikh-Patel A,Kizer KW

更新日期：2017-11-20 00:00:00

abstract：AIM OF DATABASE:The aim of the Danish Anaesthesia Database (DAD) is the nationwide collection of data on all patients undergoing anesthesia. Collected data are used for quality assurance, quality development, and serve as a basis for research projects. STUDY POPULATION:The DAD was founded in 2004 as a part of Danish C...

journal_title：Clinical epidemiology

authors： Antonsen K,Rosenstock CV,Lundstrøm LH

更新日期：2016-10-25 00:00:00