Use of existing data sources in clinical epidemiology: Finnish health care registers in Alzheimer's disease research - the Medication use among persons with Alzheimer's disease (MEDALZ-2005) study.

abstract：Background:The Swedish Quality Register for Inflammatory Bowel Disease (SWIBREG) contains clinical data for the study of inflammatory bowel disease (IBD). The Epidemiology Strengthened by histoPathology Reports in Sweden (ESPRESSO) cohort was recently established for the study of gastrointestinal histopathology. We aim...

journal_title：Clinical epidemiology

authors： Axelrad JE,Sachs MC,Ludvigsson JF,Olén O,SWIBREG Study Group.

更新日期：2020-10-09 00:00:00

abstract：:Routinely-collected health data (RCD) are now used for a wide range of studies, including observational studies, comparative effectiveness research, diagnostics, studies of adverse effects, and predictive analytics. At the same time, limitations inherent in using data collected without specific a priori research quest...

journal_title：Clinical epidemiology

authors： Nicholls SG,Langan SM,Sørensen HT,Petersen I,Benchimol EI

更新日期：2016-10-19 00:00:00

abstract：OBJECTIVE:In medicine, many more prediction models have been developed than are implemented or used in clinical practice. These models cannot be recommended for clinical use before external validity is established. Though various models to predict mortality in dialysis patients have been published, very few have been v...

journal_title：Clinical epidemiology

authors： Ramspek CL,Voskamp PW,van Ittersum FJ,Krediet RT,Dekker FW,van Diepen M

更新日期：2017-09-05 00:00:00

abstract：:The management of brain-dead organ donors is complex. The use of inotropic agents and replacement of depleted hormones (hormonal replacement therapy) is crucial for successful multiple organ procurement, yet the optimal hormonal replacement has not been identified, and the statistical adjustment to determine the best ...

journal_title：Clinical epidemiology

authors： Mi Z,Novitzky D,Collins JF,Cooper DK

更新日期：2014-12-22 00:00:00

abstract：Background:Participation in cervical cancer screening varies by socioeconomic status. The aims were to assess if offering human papilloma virus (HPV) self-sampling kits has an effect on screening participation among various socioeconomic groups and to determine if two invitation strategies for offering self-sampling in...

journal_title：Clinical epidemiology

authors： Tranberg M,Bech BH,Blaakær J,Jensen JS,Svanholm H,Andersen B

更新日期：2018-08-23 00:00:00

abstract：Objective:To evaluate the long-term risk of stroke and poststroke adverse outcomes in patients with heart failure (HF). Methods:We used research data from Taiwan's National Health Insurance Program from 2000 to 2005 and identified 20,072 adults aged ≥30 years who were newly diagnosed with HF. Frequency matching based ...

journal_title：Clinical epidemiology

authors： Tai YH,Chang CC,Yeh CC,Sung LC,Hu CJ,Cherng YG,Chen TL,Liao CC

更新日期：2020-11-05 00:00:00

abstract：BACKGROUND:The study objective was to compare the Newcastle-Ottawa Scale (NOS) and the RTI item bank (RTI-IB) and estimate interrater agreement using the RTI-IB within a systematic review on the cardiovascular safety of glucose-lowering drugs. METHODS:We tailored both tools and added four questions to the RTI-IB. Two ...

journal_title：Clinical epidemiology

authors： Margulis AV,Pladevall M,Riera-Guardia N,Varas-Lorenzo C,Hazell L,Berkman ND,Viswanathan M,Perez-Gutthann S

更新日期：2014-10-10 00:00:00

abstract：Purpose:To identify the characteristics and initial disease severity of patients with nonalcoholic fatty liver disease (NAFLD) and assess incidence and risk factors for disease progression in a retrospective study. Methods:Patients ≥18 years of age without alcoholism or other liver diseases (eg, hepatitis B/C) were se...

journal_title：Clinical epidemiology

authors： Simeone JC,Bae JP,Hoogwerf BJ,Li Q,Haupt A,Ali AK,Boardman MK,Nordstrom BL

更新日期：2017-12-14 00:00:00

abstract：Purpose:Synthetic oxytocin for labor augmentation during birth has been linked to negative neurodevelopment effects in children. We examined whether maternal labor augmentation was associated with lower cognitive ability in young adulthoods. Patients and methods:We identified 330,107 individuals (96.6% were men), with...

journal_title：Clinical epidemiology

authors： Stokholm L,Talge NM,Christensen GT,Juhl M,Mortensen LH,Strandberg-Larsen K

更新日期：2018-11-26 00:00:00

abstract：Background:Primary care databases represent a rich source of data for health care research; however, the quality of recording of secondary care events in these databases is uncertain. This study sought to investigate the completeness of recording of hospital admissions for bleeds in primary care records and explore the...

journal_title：Clinical epidemiology

authors： McDonald L,Sammon CJ,Samnaliev M,Ramagopalan S

更新日期：2018-09-04 00:00:00

abstract：PURPOSE:Large-scale observational studies based on existing medical databases may have an important role in studies of long-term effects of different treatments in prostate cancer patients if the coding of the treatment is valid. We therefore estimated the positive predictive value (PPV) and negative predictive value (...

journal_title：Clinical epidemiology

authors： Jespersen CG,Borre M,Nørgaard M

更新日期：2012-01-01 00:00:00

abstract：Purpose:Obesity is an established risk factor for venous thromboembolism (VTE), while studies on physical inactivity and VTE risk show conflicting results. We examined whether physical activity modified the association between obesity and VTE. Patients and Methods:We conducted a population-based cohort study by combin...

journal_title：Clinical epidemiology

authors： Solli H,Olsen M,Larsen FB,Pedersen L,Schmidt M

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND:Large-scale clinical registries are increasingly recognized as important resources for quality assurance and research to inform clinical decision-making and health policy. We established a clinical registry (SpineData) in a conservative care setting where more than 10,000 new cases of spinal pain are assesse...

journal_title：Clinical epidemiology

authors： Kent P,Kongsted A,Jensen TS,Albert HB,Schiøttz-Christensen B,Manniche C

更新日期：2015-08-13 00:00:00

abstract：PURPOSE:The primary objective of this study is to examine the race-specific associations between statin use and overall mortality, as well as cardiovascular and cancer mortality, among blacks and whites in the Southeastern United States (US). Little is known about these associations in blacks. PATIENTS AND METHODS:The...

journal_title：Clinical epidemiology

authors： Lipworth L,Fazio S,Kabagambe EK,Munro HM,Nwazue VC,Tarone RE,McLaughlin JK,Blot WJ,Sampson UK

更新日期：2013-12-19 00:00:00

abstract：BACKGROUND:Osteonecrosis of the jaw (ONJ) is an adverse effect of drugs that suppress bone turnover - for example, drugs used for the treatment of postmenopausal osteoporosis. The Danish National Registry of Patients (DNRP) is potentially valuable for monitoring ONJ and its prognosis; however, no specific code for ONJ ...

journal_title：Clinical epidemiology

authors： Gammelager H,Sværke C,Noerholt SE,Neumann-Jensen B,Xue F,Critchlow C,Bergdahl J,Lagerros YT,Kieler H,Tell GS,Ehrenstein V

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Although hypertrophic scar (HTS) formation following cleft lip repair is relatively common, published rates vary widely, from 1% to nearly 50%. The risk factors associated with HTS formation in cleft patients are not well characterized. The primary aim of this retrospective study of 180 cleft lip repairs is ...

journal_title：Clinical epidemiology

authors： Soltani AM,Francis CS,Motamed A,Karatsonyi AL,Hammoudeh JA,Sanchez-Lara PA,Reinisch JF,Urata MM

更新日期：2012-01-01 00:00:00

abstract：Background:Hydroxychloroquine and chloroquine may reduce the risk of cancer as they inhibit autophagy, in particular, in people with connective tissue diseases. Methods:The hazard ratios of cancers, metastases, and death were assessed in adults with connective tissue diseases prescribed hydroxychloroquine/chloroquine ...

journal_title：Clinical epidemiology

authors： Fardet L,Nazareth I,Petersen I

更新日期：2017-11-03 00:00:00

abstract：Purpose:Substantial heterogeneity exists in reported kidney function decline in pre-dialysis chronic kidney disease (CKD). By design, kidney function decline can be studied in CKD 3-5 cohorts or dialysis-based studies. In the latter, patients are selected based on the fact that they initiated dialysis, possibly leading...

journal_title：Clinical epidemiology

authors： Janmaat CJ,van Diepen M,van Hagen CC,Rotmans JI,Dekker FW,Dekkers OM

更新日期：2018-05-25 00:00:00

abstract：:When healthcare professionals have the choice between several drug treatments for their patients, they often experience considerable decision uncertainty because many decisions simply have no single "best" choice. The challenges are manifold and include that guideline recommendations focus on randomized controlled tri...

journal_title：Clinical epidemiology

authors： Meid AD,Ruff C,Wirbka L,Stoll F,Seidling HM,Groll A,Haefeli WE

更新日期：2020-11-02 00:00:00

abstract：Purpose:Former studies have suggested that women with Crohn's disease (CD) and ulcerative colitis (UC) have a decreased chance of a live born child after assisted reproductive technology (ART) treatment. It is debated whether corticosteroids before ART may improve outcomes, either by decreasing inflammatory bowel disea...

journal_title：Clinical epidemiology

authors： Nørgård BM,Larsen MD,Friedman S,Fedder J

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:With the emergence of new lipid-lowering therapies, more patients are expected to achieve substantial lowering of low-density lipoprotein cholesterol (LDL-C). However, there are limited data examining the clinical experience of patients with low (<1.3 mmol/L) or very low (<0.65 mmol/L) levels of LDL-C. To pr...

journal_title：Clinical epidemiology

authors： Schmidt SA,Heide-Jørgensen U,Manthripragada AD,Ehrenstein V

更新日期：2015-02-26 00:00:00

abstract：Objective:Reports on the epidemiology of vestibular schwannoma (VS) indicate an increase in diagnosed cases, often based on selected materials over a limited period of time. This report presents prospective 40-year epidemiological data from an unselected national cohort of all patients diagnosed with a VS in Denmark si...

journal_title：Clinical epidemiology

authors： Reznitsky M,Petersen MMBS,West N,Stangerup SE,Cayé-Thomasen P

更新日期：2019-11-08 00:00:00

abstract：:Introduction: Spontaneous (non-traumatic) subarachnoid hemorrhage (ntSAH) is frequently suspected in the emergency department, but the incidence rate is low. Diagnosis registers can provide valuable data for research in uncommon conditions like ntSAH. Unfortunately, validity vary in the registers. We aimed to assess t...

journal_title：Clinical epidemiology

authors： Sonne A,Andersen JB,Rasmussen LS

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:A number of population-based studies have demonstrated lower cancer survival in elderly patients than among middle-aged or younger patients. Also, data quality in cancer registries has been shown to be associated with age. The objective of this study was to examine the recent age-specific cancer survival tre...

journal_title：Clinical epidemiology

authors： Innos K,Lang K,Pärna K,Aareleid T

更新日期：2015-07-29 00:00:00

abstract：PURPOSE:Rotavirus (RV) is a leading cause of severe gastroenteritis (GE) in children across the world. As there is a lack of epidemiological data for RV gastroenteritis (RVGE) in Saudi Arabia, this hospital-based study was designed to estimate the disease burden of RVGE and assess the prevalent RV types in Saudi childr...

journal_title：Clinical epidemiology

authors： Khalil M,Azhar E,Kao M,Al-Kaiedi N,Alhani H,Al Olayan I,Pawinski R,Gopala K,Kandeil W,Anis S,Van Doorn LJ,DeAntonio R

更新日期：2015-02-11 00:00:00

abstract：AIM OF DATABASE:The aim of the National Database of Geriatrics is to monitor the quality of interdisciplinary diagnostics and treatment of patients admitted to a geriatric hospital unit. STUDY POPULATION:The database population consists of patients who were admitted to a geriatric hospital unit. Geriatric patients can...

journal_title：Clinical epidemiology

authors： Kannegaard PN,Vinding KL,Hare-Bruun H

更新日期：2016-10-25 00:00:00

abstract：BACKGROUND:Comorbidity indices summarize complex medical histories into concise ordinal scales, facilitating stratification and regression in epidemiologic analyses. Low subject prevalence in the highest strata of a comorbidity index often prompts combination of upper categories into a single stratum ('collapsing'). O...

journal_title：Clinical epidemiology

authors： Ahern TP,Bosco JL,Silliman RA,Yood MU,Field TS,Wei F,Lash TL

更新日期：2009-08-09 00:00:00

abstract：Purpose:This paper aims to compare the clinical effectiveness of oral anti-osteoporosis drugs based on the observed risk of fracture while on treatment in primary care actual practice. Materials and methods:We investigated two primary care records databases covering UK National Health Service (Clinical Practice Resear...

journal_title：Clinical epidemiology

authors： Khalid S,Calderon-Larrañaga S,Hawley S,Ali MS,Judge A,Arden N,van Staa T,Cooper C,Javaid MK,Prieto-Alhambra D

更新日期：2018-10-09 00:00:00

abstract：Objective:Maternal thyroid disease (TD) during pregnancy is associated with adverse birth outcomes, but little is known on its long-term outcomes. We aimed to examine if children born to mothers with TD have increased disease risk during childhood and adolescence. Patients and methods:A register-based cohort study was...

journal_title：Clinical epidemiology

authors： Jølving LR,Nielsen J,Kesmodel US,Nielsen RG,Nørgård BM,Beck-Nielsen SS

更新日期：2018-09-28 00:00:00

abstract：BACKGROUND:Validation of definitions used to identify conditions of interest is imperative to epidemiologic studies based on routinely collected data. The objective of the study was thus to estimate positive predictive values (PPVs) of International Classification of Diseases, 10th Revision (ICD-10) codes to identify c...

journal_title：Clinical epidemiology

authors： Munch T,Christensen LB,Adelborg K,Tell GS,Apalset EM,Westerlund A,Lagerros YT,Kahlert J,Xue F,Ehrenstein V

更新日期：2017-08-17 00:00:00