Abstract:
BACKGROUND:Administrative data may be useful for epidemiological studies of chronic idiopathic thrombocytopenic purpura (ITP). However, the quality of the recorded diagnoses needs evaluation. AIM:We evaluated the validity in predicting chronic ITP of the International Classification of Diseases (ICD)-10 diagnoses of ITP in the Danish National Registry of Patients (NRP). METHODS:We used the NRP to identify patients with ITP, according to code D69.3, from January 1, 1996 to December 31, 2007. We defined chronic ITP as lasting longer than 6 months by including only patients with 2 or more hospital ITP diagnoses over longer than 6 months. We confirmed diagnoses by evaluating each candidate chronic ITP patient's medical chart and estimating the positive predictive value (PPV) and 95% confidence interval (CI) of the recorded NRP diagnostic code. RESULTS:We identified 513 patients with chronic ITP in the NRP. We were able to retrieve the charts of 439. After evaluation of the charts, 410 patients were deemed to have a valid diagnosis of chronic ITP, yielding a PPV of 0.93 (95% CI: 0.91-0.96). CONCLUSION:The validity of this procedure to identify chronic ITP patients was high. The NRP is valid for epidemiological studies of patients with chronic ITP.
journal_name
Clin Epidemioljournal_title
Clinical epidemiologyauthors
Heden KE,Jensen AØ,Farkas DK,Nørgaard Mdoi
10.2147/clep.s4832subject
Has Abstractpub_date
2009-08-09 00:00:00pages
7-10issn
1179-1349journal_volume
1pub_type
杂志文章abstract:BACKGROUND:The aim of the present study was to validate the data in the Aarhus Sarcoma Registry (ASR), to determine if this registry is population-based for western Denmark, and to examine the incidence of sarcomas using validated, population-based registry data. METHODS:This study was based on patients with bone and ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S41835
更新日期:2013-03-06 00:00:00
abstract::[This corrects the article DOI: 10.2147/CLEP.S249903.]. ...
journal_title:Clinical epidemiology
pub_type: 杂志文章,已发布勘误
doi:10.2147/CLEP.S259005
更新日期:2020-04-29 00:00:00
abstract:Objective:To determine the association of individual antidepressants (ADs) with the risk of traumatic brain injury (TBI) in the elderly. Patients and methods:We conducted a case-control study nested in a cohort of new users of ADs aged ≥65 years, identified in the German Pharmacoepidemiological Research Database durin...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S173667
更新日期:2019-02-15 00:00:00
abstract:Background:The presence of comorbid medical conditions can significantly affect a cancer patient's treatment options, quality of life, and survival. However, these important data are often lacking from population-based cancer registries. Leveraging routine linkage to hospital discharge data, a comorbidity score was cal...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S146395
更新日期:2017-11-20 00:00:00
abstract:Aim:The EPICHRONIC (EPIdemiology of CHRONIC diseases) project investigated the possibility of developing common procedures for French and Spanish electronic health care databases to enable large-scale pharmacoepidemiological studies on chronic diseases. A feasibility study assessed the prevalence of type 2 diabetes mel...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S151890
更新日期:2018-07-27 00:00:00
abstract:Purpose:Former studies have suggested that women with Crohn's disease (CD) and ulcerative colitis (UC) have a decreased chance of a live born child after assisted reproductive technology (ART) treatment. It is debated whether corticosteroids before ART may improve outcomes, either by decreasing inflammatory bowel disea...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S234996
更新日期:2020-03-23 00:00:00
abstract::The management of brain-dead organ donors is complex. The use of inotropic agents and replacement of depleted hormones (hormonal replacement therapy) is crucial for successful multiple organ procurement, yet the optimal hormonal replacement has not been identified, and the statistical adjustment to determine the best ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S71403
更新日期:2014-12-22 00:00:00
abstract:Purpose:To validate the use of International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes to identify patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in the Taiwan National Health Insurance (NHI) Outpatient Claims Dataset. Methods:We conducted ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S236823
更新日期:2020-02-20 00:00:00
abstract:BACKGROUND:Physical activity (PA) and its relationship with all-cause mortality suggest a strong and consistent inverse association. This study prospectively investigated the association between PA level and mortality among participants of the Norwegian Women and Cancer (NOWAC) Study. METHODS:A total of 66,136 NOWAC p...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S22681
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Invasive bladder cancer (IBC) is a common urological malignancy accounting for 4%-5% of all cancers in Denmark. Our aim was to examine possible changes in short- and long-term survival of patients with IBC during 1998-2009. STUDY DESIGN AND SETTING:Data on all patients (N = 4032) with an incident diagnosis o...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S20615
更新日期:2011-01-01 00:00:00
abstract:Purpose:To identify the characteristics and initial disease severity of patients with nonalcoholic fatty liver disease (NAFLD) and assess incidence and risk factors for disease progression in a retrospective study. Methods:Patients ≥18 years of age without alcoholism or other liver diseases (eg, hepatitis B/C) were se...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S144368
更新日期:2017-12-14 00:00:00
abstract:Background:The combination of organized cervical cancer screening and childhood HPV vaccination programs has the potential to eliminate cervical cancer in the future. However, only women participating in both programs gain the full protection, and combined non-attenders remain at high risk of developing cervical cancer...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S203023
更新日期:2019-11-08 00:00:00
abstract:BACKGROUND:Although hypertrophic scar (HTS) formation following cleft lip repair is relatively common, published rates vary widely, from 1% to nearly 50%. The risk factors associated with HTS formation in cleft patients are not well characterized. The primary aim of this retrospective study of 180 cleft lip repairs is ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S31119
更新日期:2012-01-01 00:00:00
abstract:AIM OF DATABASE:The aim of the National Database of Geriatrics is to monitor the quality of interdisciplinary diagnostics and treatment of patients admitted to a geriatric hospital unit. STUDY POPULATION:The database population consists of patients who were admitted to a geriatric hospital unit. Geriatric patients can...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S99473
更新日期:2016-10-25 00:00:00
abstract::Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the most important causes of nosocomial infections worldwide. Since the global spread of MRSA in the 1960s, MRSA strains have evolved with increased pathogenic potential. Notably, some strains are now capable of causing persistent infections not only in...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S37071
更新日期:2013-07-04 00:00:00
abstract:Background:Decision makers in health care increasingly rely on nonrandomized database analyses to assess the effectiveness, safety, and value of medical products. Health care data scientists use data-adaptive approaches that automatically optimize confounding control to study causal treatment effects. This article summ...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S166545
更新日期:2018-07-06 00:00:00
abstract:BACKGROUND:A number of studies have shown poorer survival among cancer patients with comorbidity. Several mechanisms may underlie this finding. In this review we summarize the current literature on the association between patient comorbidity and cancer prognosis. Prognostic factors examined include tumor biology, diagn...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S47150
更新日期:2013-11-01 00:00:00
abstract:Purpose:Sharing of detailed individual-level data continues to pose challenges in multi-center studies. This issue can be addressed in part by using analytic methods that require only summary-level information to perform the desired multivariable-adjusted analysis. We examined the feasibility and empirical validity of ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S178163
更新日期:2018-11-27 00:00:00
abstract:BACKGROUND:To date there has not been any nationwide age-standardized incidence data reported for prostate cancer in Nigeria. We examined and integrated diverse trends in the age-specific incidence of prostate cancer into a comprehensive trend for Nigeria, and examined how best the existing data could generate a countr...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S23536
更新日期:2012-01-01 00:00:00
abstract:Purpose:Substantial heterogeneity exists in reported kidney function decline in pre-dialysis chronic kidney disease (CKD). By design, kidney function decline can be studied in CKD 3-5 cohorts or dialysis-based studies. In the latter, patients are selected based on the fact that they initiated dialysis, possibly leading...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S153367
更新日期:2018-05-25 00:00:00
abstract:Background and aims:Canada's large geographic area and low population density pose challenges in access to specialized health care for remote and rural residents. We compared health services use, surgical rate, and specialist gastroenterologist care in rural and urban inflammatory bowel disease (IBD) patients in Canada...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S178056
更新日期:2018-11-08 00:00:00
abstract:BACKGROUND:Data from the Nordic health care registers have been of great value in perinatal epidemiological research. It has been assumed that findings from the Nordic population (Denmark, Finland, Iceland, Norway, and Sweden) are applicable to other populations as well, including the population of the US. OBJECTIVE:T...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S106126
更新日期:2016-08-03 00:00:00
abstract:BACKGROUND:Validation of definitions used to identify conditions of interest is imperative to epidemiologic studies based on routinely collected data. The objective of the study was thus to estimate positive predictive values (PPVs) of International Classification of Diseases, 10th Revision (ICD-10) codes to identify c...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S139895
更新日期:2017-08-17 00:00:00
abstract:PURPOSE:Lifestyle factors may influence observed associations between proton pump inhibitor (PPI) usage and health outcomes. The aim of the study reported here was to examine characteristics and differences in lifestyle among PPI users and nonusers. METHODS:This cross-sectional study utilized data from a 2006 populati...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S49354
更新日期:2013-12-04 00:00:00
abstract:Objective:To investigate the impact of moderate wine consumption on the risk of prostate cancer (PCa). We focused on the differential effect of moderate consumption of red versus white wine. Design:This study was a meta-analysis that includes data from case-control and cohort studies. Materials and methods:A systemat...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S163668
更新日期:2018-04-17 00:00:00
abstract:INTRODUCTION:Few modern population-based estimates of the prognosis of ruptured abdominal aortic aneurysm (rAAA) exist. METHODS AND MATERIALS:From 1994-2008, a total of 6954 rAAA cases were identified in Danish nationwide population-based registries. RESULTS:Of 3148 (45%) surgery cases, 1454 (46%) died within 30 days...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S31098
更新日期:2012-01-01 00:00:00
abstract:Background:Association between psoriasis severity and cerebro- and cardiovascular comorbidities has rarely been investigated. Aim:We aimed to investigate differences in cerebro- and cardiovascular comorbidities by psoriasis severity. Materials and methods:Using Swedish nationwide health-care registers, new adult user...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S164918
更新日期:2018-06-19 00:00:00
abstract:AIM OF DATABASE:The Danish Nonmelanoma Skin Cancer Dermatology Database was established in 2008. The aim of this database was to collect data on nonmelanoma skin cancer (NMSC) treatment and improve its treatment in Denmark. NMSC is the most common malignancy in the western countries and represents a significant challen...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S99464
更新日期:2016-10-25 00:00:00
abstract:BACKGROUND:The study objective was to compare the Newcastle-Ottawa Scale (NOS) and the RTI item bank (RTI-IB) and estimate interrater agreement using the RTI-IB within a systematic review on the cardiovascular safety of glucose-lowering drugs. METHODS:We tailored both tools and added four questions to the RTI-IB. Two ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S66677
更新日期:2014-10-10 00:00:00
abstract:Purpose:To establish the validity of intracerebral hemorrhage (ICH) diagnoses in the Danish Stroke Registry (DSR) and the Danish National Patient Registry (DNPR). Patients and Methods:Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S267583
更新日期:2020-12-01 00:00:00