Abstract:
OBJECTIVE:Invasive bladder cancer (IBC) is a common urological malignancy accounting for 4%-5% of all cancers in Denmark. Our aim was to examine possible changes in short- and long-term survival of patients with IBC during 1998-2009. STUDY DESIGN AND SETTING:Data on all patients (N = 4032) with an incident diagnosis of IBC within a population of 1.8 million were retrieved from the Danish National Registry of Patients from 1998 to 2009. We computed survival after 1, 3, and 5 years, stratified by age and gender, and estimated mortality rate ratios (MRR) using Cox proportional hazard regression to compare mortality over time, controlling for age and gender. Data on tumor stage or histology were not included. RESULTS:During the study period, the annual numbers of incident IBC patients remained stable. The median age was 74 years in each of the four 3-year periods in the study. The survival was relatively stable during the first three periods, whilst data from the last period showed modest improvement. The overall 1-year survival increased from 68% in 1998-2000 to 70% in 2007-2009, corresponding to an age and gender adjusted MRR of 0.89 (95% confidence interval [CI] 0.76-1.03). The 3- and 5-year survival was predicted to increase from 44% to 49% and from 35% to 40% respectively. This corresponded to a 3-year age and gender adjusted MRR of 0.87 (95% CI 0.77-0.98) and a 5-year MRR of 0.88 (95% CI 0.79-0.99). The 1-, 3-, and 5-year survival increased for men in all age groups (<70 years, 70-79 years, ≥80 years) and in women only in the 70-79-year age group. CONCLUSION:The survival of IBC patients increased slightly in northern and central Denmark in the 1998-2009 period.
journal_name
Clin Epidemioljournal_title
Clinical epidemiologyauthors
Lund L,Erichsen R,Nørgaard M,Larsen EH,Borre M,Jacobsen Jdoi
10.2147/CLEP.S20615subject
Has Abstractpub_date
2011-01-01 00:00:00pages
47-51issn
1179-1349pii
clep-3-047journal_volume
3 Suppl 1pub_type
杂志文章abstract:Background:Prenatal exposures may contribute to male infertility in adult life, but large-scale epidemiological evidence is still lacking. The Fetal Programming of Semen quality (FEPOS) cohort was founded to provide means to examine if fetal exposures can interfere with fetal reproductive development and ultimately lea...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S242631
更新日期:2020-07-17 00:00:00
abstract:BACKGROUND:Validation of definitions used to identify conditions of interest is imperative to epidemiologic studies based on routinely collected data. The objective of the study was thus to estimate positive predictive values (PPVs) of International Classification of Diseases, 10th Revision (ICD-10) codes to identify c...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S139895
更新日期:2017-08-17 00:00:00
abstract:AIM OF DATABASE:The aim of the National Database of Geriatrics is to monitor the quality of interdisciplinary diagnostics and treatment of patients admitted to a geriatric hospital unit. STUDY POPULATION:The database population consists of patients who were admitted to a geriatric hospital unit. Geriatric patients can...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S99473
更新日期:2016-10-25 00:00:00
abstract:Purpose:This paper aims to compare the clinical effectiveness of oral anti-osteoporosis drugs based on the observed risk of fracture while on treatment in primary care actual practice. Materials and methods:We investigated two primary care records databases covering UK National Health Service (Clinical Practice Resear...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S164112
更新日期:2018-10-09 00:00:00
abstract:BACKGROUND:Primary hyperparathyroidism (pHPT) is associated with an increased risk of developing breast cancer, but little is known about the underlying factors. The aim of this study was to compare women with a history of pHPT and a reference population in terms of standard factors predictive of prognosis and response...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S17298
更新日期:2011-03-25 00:00:00
abstract:INTRODUCTION:Few modern population-based estimates of the prognosis of ruptured abdominal aortic aneurysm (rAAA) exist. METHODS AND MATERIALS:From 1994-2008, a total of 6954 rAAA cases were identified in Danish nationwide population-based registries. RESULTS:Of 3148 (45%) surgery cases, 1454 (46%) died within 30 days...
journal_title:Clinical epidemiology
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
abstract:Background:In 2012, liver cancer ranked as the fifth and eighth most common cancer in men and women, respectively, in urban Shanghai. This study aims to present the trend and projection of age-specific incidence and mortality of liver cancer in Shanghai. Methods:We extracted data of liver cancer incident cases and dea...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S153951
更新日期:2018-03-09 00:00:00
abstract:Purpose:Inherited ichthyosis is a monogenetic disease characterized by hyperkeratosis and scaling of the skin, with large interindividual variation in severity. It can affect quality of life for patients and their families. Population-based data on inherited ichthyosis are lacking, which hampers studies into its epidem...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S232956
更新日期:2020-06-19 00:00:00
abstract:Aim:To improve consistency between register studies in Sweden and ensure valid comparisons of possible changes in alcohol-related disorders and diseases (ARDDs) over time, we propose a definition of ARDDs. Based on this definition, we examined Sweden's incidence rates of ARDDs from 1970 to 2018 in non-primary healthcar...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S285936
更新日期:2020-12-31 00:00:00
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journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S99464
更新日期:2016-10-25 00:00:00
abstract::[This corrects the article DOI: 10.2147/CLEP.S249903.]. ...
journal_title:Clinical epidemiology
pub_type: 杂志文章,已发布勘误
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更新日期:2020-04-29 00:00:00
abstract:OBJECTIVES:Translational epidemiology studies often use archived tumor specimens to evaluate genetic hypotheses involving cancer outcomes. When the exposure of interest is a germline polymorphism, a key concern is whether the genotype assayed from tumor-derived DNA is representative of the germline. We evaluated the co...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S13811
更新日期:2010-10-22 00:00:00
abstract:BACKGROUND:Assessment of psychosocial functioning in people with schizophrenia is important. The Global Assessment of Functioning (GAF-F) scale represents a widely applied, easy, and quick tool, but its validity and reliability have been debated. The aim was to investigate whether GAF-F scores are associated with other...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S109036
更新日期:2016-09-02 00:00:00
abstract:AIM:In 2008, the Danish National Chronic Lymphocytic Leukemia Registry was founded within the Danish National Hematology Database. The primary aim of the registry is to assure quality of diagnosis and care of patients with chronic lymphocytic leukemia (CLL) in Denmark. Secondarily, to evaluate adherence to national gui...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S99486
更新日期:2016-10-25 00:00:00
abstract:BACKGROUND:Data on the safety of selective serotonin-reuptake inhibitors (SSRIs) in pregnancy are inconsistent. We examined associations between SSRI use during early pregnancy and risk of congenital malformations in infants. METHODS:Set in Northern Denmark, our population-based prevalence study included 216,042 women...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/clep.s9256
更新日期:2010-08-09 00:00:00
abstract::The Danish health care system provides partial reimbursement of most prescription medications in Denmark. The dispensation of prescription medications is registered in administrative databases. Each time a prescription is redeemed at a pharmacy, an electronic record is generated with information related to the user, p...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S37587
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to validate the data in the Aarhus Sarcoma Registry (ASR), to determine if this registry is population-based for western Denmark, and to examine the incidence of sarcomas using validated, population-based registry data. METHODS:This study was based on patients with bone and ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S41835
更新日期:2013-03-06 00:00:00
abstract:Objective:Reports on the epidemiology of vestibular schwannoma (VS) indicate an increase in diagnosed cases, often based on selected materials over a limited period of time. This report presents prospective 40-year epidemiological data from an unselected national cohort of all patients diagnosed with a VS in Denmark si...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S218670
更新日期:2019-11-08 00:00:00
abstract:PURPOSE:The primary objective of this study is to examine the race-specific associations between statin use and overall mortality, as well as cardiovascular and cancer mortality, among blacks and whites in the Southeastern United States (US). Little is known about these associations in blacks. PATIENTS AND METHODS:The...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S53492
更新日期:2013-12-19 00:00:00
abstract:Purpose:To validate the use of International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes to identify patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in the Taiwan National Health Insurance (NHI) Outpatient Claims Dataset. Methods:We conducted ...
journal_title:Clinical epidemiology
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更新日期:2020-02-20 00:00:00
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journal_title:Clinical epidemiology
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更新日期:2013-12-04 00:00:00
abstract:PURPOSE:Large-scale observational studies based on existing medical databases may have an important role in studies of long-term effects of different treatments in prostate cancer patients if the coding of the treatment is valid. We therefore estimated the positive predictive value (PPV) and negative predictive value (...
journal_title:Clinical epidemiology
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更新日期:2012-01-01 00:00:00
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journal_title:Clinical epidemiology
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更新日期:2014-11-13 00:00:00
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journal_title:Clinical epidemiology
pub_type: 杂志文章
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更新日期:2015-02-26 00:00:00
abstract:Purpose:Anemia is prevalent in patients with chronic kidney disease (CKD), but the longitudinal risk of anemia in patients with newly identified CKD is unknown. We therefore examined the risks of experiencing anemia in persons with newly identified CKD. Patients and Methods:This cohort study included adult patients wi...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S259648
更新日期:2020-09-11 00:00:00
abstract::Introduction: Spontaneous (non-traumatic) subarachnoid hemorrhage (ntSAH) is frequently suspected in the emergency department, but the incidence rate is low. Diagnosis registers can provide valuable data for research in uncommon conditions like ntSAH. Unfortunately, validity vary in the registers. We aimed to assess t...
journal_title:Clinical epidemiology
pub_type: 杂志文章
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更新日期:2019-05-01 00:00:00
abstract:Background:Cost-effective primary prevention of cardiovascular disease (CVD) relies on accuracy of risk assessment. Current risk scores require clinical and laboratory measures, are expensive and are often difficult to apply in the population setting. Objective:This study sought to estimate CVD risk from individuals' ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
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更新日期:2020-01-14 00:00:00
abstract:Purpose:Obesity is an established risk factor for venous thromboembolism (VTE), while studies on physical inactivity and VTE risk show conflicting results. We examined whether physical activity modified the association between obesity and VTE. Patients and Methods:We conducted a population-based cohort study by combin...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S275079
更新日期:2020-12-08 00:00:00
abstract:Background and aims:Canada's large geographic area and low population density pose challenges in access to specialized health care for remote and rural residents. We compared health services use, surgical rate, and specialist gastroenterologist care in rural and urban inflammatory bowel disease (IBD) patients in Canada...
journal_title:Clinical epidemiology
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更新日期:2018-11-08 00:00:00
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journal_title:Clinical epidemiology
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更新日期:2015-08-28 00:00:00