Factors associated with reporting multiple causes of death.

abstract：BACKGROUND:In randomised controlled trials, the assumption of independence of individual observations is fundamental to the design, analysis and interpretation of studies. However, in individually randomised trials in primary care, this assumption may be violated because patients are naturally clustered within primary ...

journal_title：BMC medical research methodology

authors： Stuart B,Becque T,Moore M,Little P

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Thresholds for statistical significance are insufficiently demonstrated by 95% confidence intervals or P-values when assessing results from randomised clinical trials. First, a P-value only shows the probability of getting a result assuming that the null hypothesis is true and does not reflect the probabilit...

journal_title：BMC medical research methodology

authors： Jakobsen JC,Gluud C,Winkel P,Lange T,Wetterslev J

更新日期：2014-03-04 00:00:00

abstract：BACKGROUND:The Anglia Menorrhagia Education Study (AMES) is a randomized controlled trial testing the effectiveness of an education package applied to general practices. Binary data are available from two sources; general practitioner reported referrals to hospital, and referrals to hospital determined by independent a...

journal_title：BMC medical research methodology

authors： Nixon RM,Duffy SW,Fender GR

更新日期：2003-09-24 00:00:00

abstract：BACKGROUND:Clinical quality registries and other systems that conduct routine post-discharge surveillance of patient outcomes following surgery may have difficulty surveying patients who have limited proficiency in the language of the healthcare provider. Interpreter proxies (family and carers) are often used due to li...

journal_title：BMC medical research methodology

authors： Xue D,Churches T,Armstrong E,Mittal R,Naylor JM,Harris IA

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:Regular and timely monitoring of blood glucose (BG) levels in hospitalized patients with diabetes mellitus is crucial to optimizing inpatient glycaemic control. However, methods to quantify timeliness as a measurement of quality of care are lacking. We propose an analytical approach that utilizes BG measurem...

journal_title：BMC medical research methodology

authors： Chen Y,Kao SL,Tai ES,Wee HL,Khoo EY,Ning Y,Salloway MK,Deng X,Tan CS

更新日期：2016-04-08 00:00:00

abstract：BACKGROUND:Interventions in occupational health often target worksites rather than individuals. The objective of this paper is to describe the (lack of) stability in units of analysis in occupational health and safety intervention projects directed toward worksites. METHODS:A case study approach is used to describe na...

journal_title：BMC medical research methodology

authors： Olsen O,Albertsen K,Nielsen ML,Poulsen KB,Gron SM,Brunnberg HL

更新日期：2008-06-13 00:00:00

abstract：BACKGROUND:Primary care databases are a major source of data for epidemiological and health services research. However, most studies are based on coded information, ignoring information stored in free text. Using the early presentation of rheumatoid arthritis (RA) as an exemplar, our objective was to estimate the exten...

journal_title：BMC medical research methodology

authors： Ford E,Nicholson A,Koeling R,Tate A,Carroll J,Axelrod L,Smith HE,Rait G,Davies KA,Petersen I,Williams T,Cassell JA

更新日期：2013-08-21 00:00:00

abstract：BACKGROUND:Discrete Choice Experiments (DCEs) are increasingly used in studies in healthcare research but there is still little empirical evidence for the predictive value of these hypothetical situations in similar real life circumstances. The aim of this paper is to compare the stated preferences in a DCE and the acc...

journal_title：BMC medical research methodology

authors： Lambooij MS,Harmsen IA,Veldwijk J,de Melker H,Mollema L,van Weert YW,de Wit GA

更新日期：2015-03-12 00:00:00

abstract：BACKGROUND:The initial vanguard cohort of the U.S. National Children's Study was a pregnancy and birth cohort study that sought to enroll some women prior to pregnancy, and to assess exposures early in pregnancy. METHODS:During the recruitment phase (2009-2010), geographically based sampling was used to recruit women ...

journal_title：BMC medical research methodology

authors： Stanford JB,Brenner R,Fetterer D,Palmer L,Schoendorf KC,U.S. National Children’s Study.

更新日期：2015-09-24 00:00:00

abstract：BACKGROUND:Information and theory beyond copula concepts are essential to understand the dependence relationship between several marginal covariates distributions. In a therapeutic trial data scheme, most of the time, censoring occurs. That could lead to a biased interpretation of the dependence relationship between ma...

journal_title：BMC medical research methodology

authors： Fontaine C,Daurès JP,Landais P

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:Joint models of longitudinal and time-to-event data are increasingly used to perform individual dynamic prediction of a risk of event. However the difficulty to perform inference in nonlinear models and to calculate the distribution of individual parameters has long limited this approach to linear mixed-effe...

journal_title：BMC medical research methodology

authors： Desmée S,Mentré F,Veyrat-Follet C,Sébastien B,Guedj J

更新日期：2017-07-17 00:00:00

abstract：BACKGROUND:Small number of clusters and large variation of cluster sizes commonly exist in cluster-randomized trials (CRTs) and are often the critical factors affecting the validity and efficiency of statistical analyses. F tests are commonly used in the generalized linear mixed model (GLMM) to test intervention effect...

journal_title：BMC medical research methodology

authors： Li P,Redden DT

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:The prevailing view in therapeutic clinical research today is that observational studies are useful for generating new hypotheses and that controlled experiments (i.e., randomized clinical trials, RCTs) are the most appropriate method for assessing and confirming the efficacy of interventions. DISCUSSION:Th...

journal_title：BMC medical research methodology

authors： Sacristán JA

更新日期：2011-04-25 00:00:00

abstract：BACKGROUND:Various papers have addressed pros and cons of the stepped wedge cluster randomized trial design (SWD). However, some issues have not or only limitedly been addressed. Our aim was to provide a comprehensive overview of all merits and limitations of the SWD to assist researchers, reviewers and medical ethics ...

journal_title：BMC medical research methodology

authors： de Hoop E,van der Tweel I,van der Graaf R,Moons KG,van Delden JJ,Reitsma JB,Koffijberg H

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:Systematic reviewers seek to comprehensively search for relevant studies and summarize these to present the most valid estimate of intervention effectiveness. The more resources searched, the higher the yield, and thus time and costs required to conduct a systematic review. While there is an abundance of evi...

journal_title：BMC medical research methodology

authors： Crumley ET,Wiebe N,Cramer K,Klassen TP,Hartling L

更新日期：2005-08-10 00:00:00

abstract：BACKGROUND:In the era of evidence based medicine, with systematic reviews as its cornerstone, adequate quality assessment tools should be available. There is currently a lack of a systematically developed and evaluated tool for the assessment of diagnostic accuracy studies. The aim of this project was to combine empiri...

journal_title：BMC medical research methodology

authors： Whiting P,Rutjes AW,Reitsma JB,Bossuyt PM,Kleijnen J

更新日期：2003-11-10 00:00:00

abstract：BACKGROUND:Disease incidence and prevalence are both core indicators of population health. Incidence is generally not as readily accessible as prevalence. Cohort studies and electronic health record systems are two major way to estimate disease incidence. The former is time-consuming and expensive; the latter is not av...

journal_title：BMC medical research methodology

authors： Hu XF,Young K,Chan HM

更新日期：2017-01-23 00:00:00

abstract：BACKGROUND:Action research (AR) and randomized controlled trials (RCTs) are usually considered to be theoretically and practically incompatible. However, we argue that their respective strengths and weaknesses can be complementary. We illustrate our argument from a recent study assessing the effect of telemonitoring on...

journal_title：BMC medical research methodology

authors： Day K,Kenealy TW,Sheridan NF

更新日期：2016-06-08 00:00:00

abstract：BACKGROUND:Clinical practice guidelines have become increasingly widely used to guide quality improvement of clinical practice. Qualitative research may be a useful way to improve the quality and implementation of guidelines. The methodology for qualitative evidence used in guidelines development is worthy of further r...

journal_title：BMC medical research methodology

authors： Wang YY,Liang DD,Lu C,Shi YX,Zhang J,Cao Y,Fang C,Huang D,Jin YH

更新日期：2020-06-17 00:00:00

abstract：BACKGROUND:Most electronic search efforts directed at identifying primary studies for inclusion in systematic reviews rely on the optimal Boolean search features of search interfaces such as DIALOG and Ovid. Our objective is to test the ability of an Ultraseek search engine to rank MEDLINE records of the included studi...

journal_title：BMC medical research methodology

authors： Sampson M,Barrowman NJ,Moher D,Clifford TJ,Platt RW,Morrison A,Klassen TP,Zhang L

更新日期：2006-02-24 00:00:00

abstract：BACKGROUND:It is widely recognised that the pursuit of sustainable development cannot be accomplished without addressing inequality, or observed differences between subgroups of a population. Monitoring health inequalities allows for the identification of health topics where major group differences exist, dimensions of...

journal_title：BMC medical research methodology

authors： Hosseinpoor AR,Nambiar D,Schlotheuber A,Reidpath D,Ross Z

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:The lack of suitable and reliable scales to measure self-reported health and health behaviour among people with intellectual disabilities (ID) is an important methodological challenge in health research. This study, which was undertaken together with co-researchers with ID, explores possibilities for self-re...

journal_title：BMC medical research methodology

authors： Vlot-van Anrooij K,Tobi H,Hilgenkamp TIM,Leusink GL,Naaldenberg J

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:The BSI-18 contains the three six-item scales somatization, depression, and anxiety as well as the Global Severity Index (GSI), including all 18 items. The BSI-18 is the latest and shortest of the multidimensional versions of the Symptom-Checklist 90-R, but its psychometric properties have not been sufficien...

journal_title：BMC medical research methodology

authors： Franke GH,Jaeger S,Glaesmer H,Barkmann C,Petrowski K,Braehler E

更新日期：2017-01-26 00:00:00

abstract：BACKGROUND:Glaucoma is a leading cause of avoidable blindness worldwide. Open angle glaucoma is the most common type of glaucoma. No randomised controlled trials have been conducted evaluating the effectiveness of glaucoma screening for reducing sight loss. It is unclear what the most appropriate intervention to be eva...

journal_title：BMC medical research methodology

authors： Glaucoma screening Platform Study group.,Burr JM,Campbell MK,Campbell SE,Francis JJ,Greene A,Hernández R,Hopkins D,McCann SK,Vale LD

更新日期：2011-04-21 00:00:00

abstract：BACKGROUND:International clinical trials are now rapidly expanding into Asia. However, the proportion of global trials is higher in South Korea compared to Japan despite implementation of similar governmental support in both countries. The difference in clinical trial environment might influence the respective physicia...

journal_title：BMC medical research methodology

authors： Ito-Ihara T,Hong JH,Kim OJ,Sumi E,Kim SY,Tanaka S,Narita K,Hatta T,Choi EK,Choi KJ,Miyagawa T,Minami M,Murayama T,Yokode M

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Diabetes-related lower limb amputations are associated with considerable morbidity and mortality and are usually preceded by foot ulceration. The available systematic reviews of aggregate data are compromised because the primary studies report both adjusted and unadjusted estimates. As adjusted meta-analyses...

journal_title：BMC medical research methodology

authors： Crawford F,Anandan C,Chappell FM,Murray GD,Price JF,Sheikh A,Simpson CR,Maxwell M,Stansby GP,Young MJ,Abbott CA,Boulton AJ,Boyko EJ,Kastenbauer T,Leese GP,Monami M,Monteiro-Soares M,Rith-Najarian SJ,Veves A,Coates N

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:In low-income settings, key outcomes such as biomarkers or clinical assessments are often missing for a substantial proportion of the study population. The aim of this study was to assess the extent to which Heckman-type selection models can create unbiased estimates in such settings. METHODS:We introduce t...

journal_title：BMC medical research methodology

authors： Koné S,Bonfoh B,Dao D,Koné I,Fink G

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:This article describes the design and baseline sample of a single-site trial comparing Individual Placement and Support (IPS) supported employment delivered within a Veterans Health Administration (VHA) primary care Patient Aligned Care Team (PACT) to treatment-as-usual vocational rehabilitation (TAU-VR) tha...

journal_title：BMC medical research methodology

authors： Davis LL,Blansett CM,Mumba MN,MacVicar D,Toscano R,Pilkinton P,Gay W,Bartolucci A

更新日期：2020-02-17 00:00:00

abstract：BACKGROUND:Epidemiologic studies often struggle to adequately represent populations and outcomes of interest. Differences in methodology, data analysis and research questions often mean that reviews and synthesis of the existing literature have significant limitations. The current paper details our experiences in combi...

journal_title：BMC medical research methodology

authors： Allen J,Inder KJ,Lewin TJ,Attia JR,Kay-Lambkin FJ,Baker AL,Hazell T,Kelly BJ

更新日期：2013-10-05 00:00:00

abstract：BACKGROUND:Evidence suggests that differences exist in physical activity (PA) participation among Culturally and Linguistically Diverse (CALD) children and adolescents. It is possible that these differences could be influenced by variations in measurement technique and instrument reliability. However, culturally sensit...

journal_title：BMC medical research methodology

authors： Strugnell C,Renzaho A,Ridley K,Burns C

更新日期：2011-08-25 00:00:00