当前位置： SCI文献检索 > JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION期刊下所有文献 > Hormonal and metabolic changes in starving obese patients during exhaustive physical exercise.

Hormonal and metabolic changes in starving obese patients during exhaustive physical exercise.

Abstract：

:Exhaustive graded exercise leads to changes of hormones, carbohydrate, and lipid metabolism in normal controls and obese patients after prolonged starvation. Concomitant with a large increase of plasma catecholamines, insulin concentration is reduced and blood glucose levels slowly increase. More glucose is made available by glycogenolysis and gluconeogenesis than can be oxidized in the mitochondria. Lactate associated metabolic acidosis appears. Starving obese patients in the basal state have reduced blood glucose concentrations, but their initial values for free glycerol, free fatty acids, and ketone bodies are much higher than in normal controls. This is caused by the starvation induced lipolysis. With exhaustive exercise adrenaline, noradrenaline, and free glycerol increase. In contrast, free fatty acids and ketone bodies decrease, because they are consumed as fuel. Prolonged starvation changes basal values of hormones and metabolites, but it does not change the quality of exercise-induced shifts in these values when compared with those of the normal controls.

journal_name

J Endocrinol Invest

journal_title

Journal of endocrinological investigation

authors

Jakober B,Schmülling RM,Müller PH,Eggstein M

doi

10.1007/BF03348344

subject

Has Abstract

pub_date

1983-12-01 00:00:00

pages

445-53

issue

6

eissn

0391-4097

issn

1720-8386

journal_volume

6

pub_type

杂志文章

相关文献

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION文献大全
  • Investigating the effect of testosterone by itself and in combination with letrozole on 1,25-dihydroxy vitamin D and FGF23 in male rats.

    abstract：BACKGROUND:Testosterone deficiency might be associated with vitamin D levels in hypogonadal men, but it is not clear whether testosterone can affect vitamin D and fibroblast growth factor-23 (FGF23), either directly or indirectly via aromatization to estradiol. We aimed to investigate the role of testosterone on vitami...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-018-0875-3

    authors： Saki F,Kasaee SR,Sadeghian F,Koohpeyma F,Omrani GHR

    更新日期：2019-01-01 00:00:00

  • Effect of 4-phenylbutyrate and valproate on dominant mutations of WFS1 gene in Wolfram syndrome.

    abstract：PURPOSE:Wolfram syndrome (WS) is a rare disorder caused by mutations in WFS1 that is characterized by diabetes mellitus, optic atrophy, sensorineural deafness, diabetes insipidus, and neurodegeneration. This disease is usually inherited as an autosomal recessive trait, but an autosomal dominant form has been reported. ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-020-01228-2

    authors： Batjargal K,Tajima T,Jimbo EF,Yamagata T

    更新日期：2020-09-01 00:00:00

  • Does early response to intravenous glucocorticoids predict the final outcome in patients with moderate-to-severe and active Graves' orbitopathy?

    abstract：PURPOSE:Intravenous glucocorticoids (ivGCs) given as 12-weekly infusions are the first-line treatment for moderate-to-severe and active Graves' orbitopathy (GO), but they are not always effective. In this study, we evaluated whether response at 6 weeks correlated with outcomes at 12 (end of intervention) and 24 (follow...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-017-0608-z

    authors： Bartalena L,Veronesi G,Krassas GE,Wiersinga WM,Marcocci C,Marinò M,Salvi M,Daumerie C,Bournaud C,Stahl M,Sassi L,Azzolini C,Boboridis KG,Mourits MP,Soeters MR,Baldeschi L,Nardi M,Currò N,Boschi A,Bernard M,von Arx

    更新日期：2017-05-01 00:00:00

  • New achievement and novel therapeutic applications of PDE5 inhibithors in older males.

    abstract：:Erectile dysfunction (ED) increases in prevalence and severity because of aging processes and related organic, iatrogenic and social problems. Decline of testosterone (T) levels is observed with age and also in illnesses with a common basis of endothelial damage. The T deficiency may lead to decreased energy, mood dep...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：

    authors： Frajese GV,Pozzi F

    更新日期：2005-01-01 00:00:00

  • Genotype, phenotype and hormonal levels correlation in non-classical congenital adrenal hyperplasia.

    abstract：:Non-classical congenital adrenal hyperplasia (NCAH) is a morbid condition sustained by the reduced function of one of the enzymes involved in the adrenal steroid biosynthesis pathway, mainly the 21-hydroxylase. Different degrees of enzyme activity impairment determine different clinical pictures, with childhood or pos...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.3275/7410

    authors： Einaudi S,Napolitano E,Restivo F,Motta G,Baldi M,Tuli G,Grosso E,Migone N,Menegatti E,Manieri C

    更新日期：2011-10-01 00:00:00

  • Association between vitamin D deficiency and risk of thyroid cancer: a case-control study and a meta-analysis.

    abstract：PURPOSE:Although vitamin D is reportedly associated with various cancers, the association between vitamin D and thyroid cancer is indefinite. We aimed to investigate whether this association applies to thyroid cancer (TC). METHODS:A total of 276 Chinese Han people were recruited in a current matched case-control study...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,meta分析

    doi：10.1007/s40618-018-0853-9

    authors： Hu MJ,Zhang Q,Liang L,Wang SY,Zheng XC,Zhou MM,Yang YW,Zhong Q,Huang F

    更新日期：2018-10-01 00:00:00

  • Association between circulating levels of adiponectin and indices of bone mass and bone metabolism in middle-aged post-menopausal women.

    abstract：BACKGROUND:Adiponectin, a fat derived cytokine, is a potential independent contributor to bone mineral density (BMD); however, its action on bone metabolism in humans is still unclear. AIM:The aim of this study was to investigate the relationship of adiponectin with bone mass indices and bone metabolic markers in midd...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.3275/7744

    authors： Tenta R,Kontogianni MD,Yiannakouris N

    更新日期：2012-03-01 00:00:00

  • A genome-wide DNA methylation analysis in peripheral blood from patients identifies risk loci associated with Graves' orbitopathy.

    abstract：OBJECTIVE:Graves' orbitopathy (GO) is an inflammatory orbital disease of autoimmune origin with the potential to cause severe functional and psychosocial effects. The pathogenesis has not been fully elucidated. We investigated whether DNA methylation was associated with GO incidence in Chinese patients. MATERIALS AND ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-017-0796-6

    authors： Xin Z,Hua L,Shi TT,Tuo X,Yang FY,Li Y,Cao X,Yang JK

    更新日期：2018-06-01 00:00:00

  • T4 but not T3 administration is associated with increased recurrence of Graves' disease after successful medical therapy.

    abstract：:TSH has been incriminated in Graves' disease for increasing the production of antibodies against TSH receptor (TRAb). It has been, therefore, suggested that T4 administration after successful antithyroid drug (ATD) treatment may indirectly decrease the production of TRAb and, therefore, the frequency of recurrence of ...

    journal_title：Journal of endocrinological investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF03348195

    authors： Mastorakos G,Doufas AG,Mantzos E,Mantzos J,Koutras DA

    更新日期：2003-10-01 00:00:00

  • Ovarian steroids modulate neuroendocrine dysfunction in polycystic ovary syndrome.

    abstract：OBJECTIVE:Neuroendocrine dysfunction in polycystic ovary syndrome (PCOS) was addressed by studying the steroid hormone changes in women with PCOS with either high or normal LH levels leading to inferences regarding the primacy of elevated LH in the pathophysiology of PCOS. METHODS:A cross-sectional study was designed ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03345319

    authors： Doi SA,Al-Zaid M,Towers PA,Scott CJ,Al-Shoumer KA

    更新日期：2005-11-01 00:00:00

  • The dynamics of 11-beta-hydroxy-androstenedione (11 OHAD) metabolism in man.

    abstract：:The aim of the study was to determine the main metabolic parameters of 11-beta-hydroxy-androstenedione (11 OHAD) in man. Seven normal subjects were investigated at 1-3 months interval by 2 types of isotope dilution techniques using a tritiated tracer: constant infusion and bolus iv injection. 3H-11 OHAD and 3H-11-beta...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03349485

    authors： Lejeune-Lenain C,Courtois P,Art G,Franckson JR

    更新日期：1984-12-01 00:00:00

  • Osteocalcin levels in patients with microprolactinoma before and during medical treatment.

    abstract：:Osteocalcin (OC) concentration, a specific index of bone formation, was measured in 29 female patients with microprolactinoma (serum prolactin, PRL: 105 +/- 10.9 ng/ml; mean +/- SE). Mean OC levels were significantly lower than in controls (1.7 +/- 0.2 vs 5.1 +/- 0.3 ng/ml; p less than 0.001), being below the normal r...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03350694

    authors： Sartorio A,Conti A,Ambrosi B,Muratori M,Morabito F,Faglia G

    更新日期：1990-05-01 00:00:00

  • Skeletal turnover, bone mineral density, and fractures in male chronic abusers of alcohol.

    abstract：BACKGROUND:Chronic alcohol abuse is a risk factor for osteoporosis and fractures, whose pathogenesis is still unclear. We investigated the influence of alcoholism and other risk factors on calcium and skeletal metabolism, bone mineral density (BMD), and fractures. MATERIALS AND METHODS:In 51 chronic male alcoholics wi...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03346365

    authors： Santori C,Ceccanti M,Diacinti D,Attilia ML,Toppo L,D'Erasmo E,Romagnoli E,Mascia ML,Cipriani C,Prastaro A,Carnevale V,Minisola S

    更新日期：2008-04-01 00:00:00

  • Malignant pancreatic oncocytoma. An unusual cause of organic hypoglycemia.

    abstract：:A case of malignant islet-cell tumor with oncocytic features occurring in a 54-year-old woman with symptoms of organic hypoglycemia is reported. The tumor was composed of ribbons of cells arranged in an endocrine pattern. The cytoplasm of these cells was eosinophilic and finely granular. Ultrastructurally, the cells c...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：10.1007/BF03348712

    authors： Sadoul JL,Saint-Paul MC,Hoffman P,Plazza M,Birtwisle Y,Freychet P,Loubiere R

    更新日期：1992-03-01 00:00:00

  • Snoring, hypertension and Type 2 diabetes in obesity. Protection by physical activity.

    abstract：:Sleep-related breathing disorders are recognized as major health problems in obesity. They are involved in both hypertension and Type 2 diabetes, through mechanisms possibly related to increased sympathetic tone. We studied the association of habitual snoring with diabetes, hypertension, weight cycling and physical ac...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03346260

    authors： Marchesini G,Pontiroli A,Salvioli G,Novi RF,Vitacolonna E,Taboga C,Ciccarone AM,Grossi E,QUOVADIS Study Group.

    更新日期：2004-02-01 00:00:00

  • Bone mineral density and body composition in male children with hypogonadism.

    abstract：:Estrogen deficiency in females and androgen deficiency in males may harm periosteal and endosteal apposition, reduce bone size and both cortical and trabecular thickness, modifying in this way the bone structure later in life. To date, few systematic studies on bone mineral density (BMD) and hypogonadism in adolescent...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03346513

    authors： Fintini D,Grossi A,Brufani C,Fiori R,Ubertini G,Pecorelli L,Cappa M

    更新日期：2009-07-01 00:00:00

  • Glucose-stimulated insulin secretion: Effects of high-fat diet and acute stress.

    abstract：BACKGROUND:One of the major topics in modern societies is the study of relationships between diet, stress and incidence of metabolic disorders. AIM:This study aimed to investigate possible impairment in glucose-stimulated insulin secretion induced by a high-fat (cow intra-abdominal fat) diet in response to acute stres...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.3275/8959

    authors： Ghalami J,Zardooz H,Rostamkhani F,Farrokhi B,Hedayati M

    更新日期：2013-11-01 00:00:00

  • Luteinizing hormone pulsatile secretion and pituitary response to gonadotropin releasing hormone and to thyrotropin releasing hormone in male epileptic subjects on chronic phenobarbital treatment.

    abstract：:Endocrine changes have been reported in treated epileptic subjects, who often exhibit sexual dysfunctions, but the endocrine effects of single antiepileptic drugs have not been completely elucidated. In this study we have investigated the influence of phenobarbital (PB) on adenopituitary function and on peripheral sex...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03347145

    authors： Murialdo G,Manni R,De Maria A,Bonura ML,Polleri A,Tartara A

    更新日期：1987-02-01 00:00:00

  • Effects of metabolic abnormalities, hyperandrogenemia and clomiphene on liver function parameters among Chinese women with polycystic ovary syndrome: results from a randomized controlled trial.

    abstract：PURPOSE:To investigate the effects of metabolic abnormalities, hyperandrogenemia and ovulation induction by clomiphene/acupuncture on liver function parameters among women with polycystic ovary syndrome (PCOS). METHODS:This is a secondary analysis of a randomized controlled trial. All 1000 subjects were diagnosed as P...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-018-0953-6

    authors： Cai WY,Gao JS,Luo X,Ma HL,Ge H,Liu N,Xia Q,Wang Y,Han BW,Wu XK

    更新日期：2019-05-01 00:00:00

  • Association of metabolic syndrome components with insulin resistance in normal weight population: the Qazvin Metabolic Diseases study.

    abstract：PURPOSE:Metabolically obese but normal weight (MONW) is associated with higher risk of type 2 diabetes, dyslipidemia, and hypertension. The aim of this study was to evaluate the association of metabolic syndrome components with MONW in each sex in Iranian population. METHODS:This cross-sectional study was performed on...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-015-0302-y

    authors： Hashemipour S,Esmailzadehha N,Hamid H,Oveisi S,Yakhchaliha P,Ziaee A

    更新日期：2015-10-01 00:00:00

  • Feedback regulation of thyrotropin-releasing hormone (TRH): mechanisms for the non-thyroidal illness syndrome.

    abstract：:Regulation of the hypothalamic-pituitary-thyroid (HPT) axis is dependent upon the secretion of thyrotropin-releasing hormone (TRH), a tripeptide originating in the hypothalamic paraventricular nucleus (PVN). These so-called hypophysiotropic neurons are under feedback inhibition by circulating levels of thyroid hormone...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：

    authors： Lechan RM,Fekete C

    更新日期：2004-01-01 00:00:00

  • New insights into vitamin D regulation: is there a role for alkaline phosphatase?

    abstract：PURPOSE:The diagnosis of vitamin D deficiency is based on the determination of total plasma 25-hydroxyvitamin D (25-OHD) concentrations, but the regulation of vitamin D 25-hydroxylation is not a major consideration and very little information is available on this activity. To check what factors could interfere with the...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-021-01503-w

    authors： Bellastella G,Scappaticcio L,Longo M,Carotenuto R,Carbone C,Caruso P,Maio A,Paglionico VA,Vietri MT,Maiorino MI,Esposito K

    更新日期：2021-01-25 00:00:00

  • Metabolic syndrome is the key determinant of impaired vaginal lubrication in women with chronic spinal cord injury.

    abstract：PURPOSE:Spinal cord injury (SCI) affects sexual health of both male and female, but little attention has been given to sexuality of SCI women. Similar to penile erection, vaginal lubrication represents a neurovascular event and then both denervation and vascular damage might contribute to its impairment. Nevertheless, ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/s40618-020-01185-w

    authors： D'Andrea S,Castellini C,Paladino V,Totaro M,Felzani G,Francavilla S,Francavilla F,Barbonetti A

    更新日期：2020-07-01 00:00:00

  • Variations of serum levels of adiponectin and resistin in chronic viral hepatitis.

    abstract：BACKGROUND AND AIMS:Several studies investigated the possible role of adipokines during chronic viral hepatitis, not producing defined results neither clearly establishing their behavior in course of anti-viral treatment. Our study evaluated blood concentrations of adiponectin and resistin in patients with chronic hepa...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.3275/8883

    authors： Durazzo M,Belci P,Niro G,Collo A,Grisoglio E,Ambrogio V,Spandre M,Fontana R,Gambino R,Cassader M,Bo S

    更新日期：2013-09-01 00:00:00

  • False-positive diagnosis of adrenal pheochromocytoma on iodine-123-MIBG scan.

    abstract：:1-123 metaiodobenzylguanidine (1-123 MIBG) scintigraphy is known for its high specificity in detecting pheochromocytoma and other tumors of neural crest origin. In this rare case report, we describe a definite adrenocortical adenoma that demonstrated false-positive uptake at I-123 MIBG scintigraphy and a remarkable ac...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03348046

    authors： Letizia C,De Toma G,Massa R,Corsi A,Caliumi C,Subioli S,D'Erasmo E

    更新日期：1998-12-01 00:00:00

  • Leptin, insulin and TNF-alpha in weight loss.

    abstract：:Forty-eight morbidly obese patients were placed on a very low calorie (800 kcal) formula diet (OPTIFAST) for a 10-week period with the goal of achieving 10% weight loss within this time. Weekly serum leptin measurements were performed to determine whether changes in this adipose protein would serve as a useful marker ...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03343943

    authors： Xenachis C,Samojlik E,Raghuwanshi MP,Kirschner MA

    更新日期：2001-12-01 00:00:00

  • Growth and final height in classical and nonclassical 21-hydroxylase deficiency.

    abstract：:Final height was evaluated in 47 patients with classical 21-hydroxylase treated since diagnosis, and in 29 patients with nonclassical (NC) 21-hydroxylase deficiency who had never been treated before reaching final adult height. Classical patients achieved final heights consistently below the mean for the general popul...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：

    authors： New MI,Gertner JM,Speiser PW,Del Balzo P

    更新日期：1989-01-01 00:00:00

  • The role of growth hormone in glucocorticoid-induced osteoporosis.

    abstract：:Glucocorticoid-induced osteoporosis (GIO) is the most common form of secondary osteoporosis. GC influence bone metabolism via a modulation of different components of the GH/IGF-I system. GH has multiple anabolic effects on bone, either direct or mediated by IGF-I. GH-deficient subjects have significant reduction in bo...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章,评审

    doi：

    authors： Lombardi G,Colarusso S,Di Somma C,Guerra E,Tauchmanova L,Colao A

    更新日期：2008-07-01 00:00:00

  • Actions of calcium ions and a calcium-influx blocker on basal and TRH- and GnRH-stimulated hormone release in patients with pituitary adenomas.

    abstract：:We investigated the influence of calcium ions on the secretion of anterior pituitary hormones basally and in response to exogenous hypothalamic releasing factors in 6 men with pituitary tumors. To this end, concentrations of LH, FSH, TSH, growth hormone and prolactin were measured in blood collected at 10-min interval...

    journal_title：Journal of endocrinological investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF03348164

    authors： Davis M,Nassberg B,Borges JL,Iranmanesh A,Lizzaralde G,Santen RJ,Drake C,Rogol AD,Kaiser DL,Thorner MO

    更新日期：1987-10-01 00:00:00

  • Human insulin-specific immunoglobulin G antibody and hypoglycemic attacks after the injection of gold thioglucose.

    abstract：:A 56-year-old woman with granulomas of gold thioglucose in her hips exhibited recurrent bouts of hypoglycemic attacks. The first attack occurred 2 years after the last injection of gold thioglucose, when large amounts of extractable insulin and human insulin-specific antibody were noted in her serum. Histological exam...

    journal_title：Journal of endocrinological investigation

    pub_type： 杂志文章

    doi：10.1007/BF03348654

    authors： Yao K,Uchigata Y,Kyono H,Yokoyama H,Eguchi Y,Fukushima H,Yamauchi K,Hirata Y

    更新日期：1992-01-01 00:00:00