Seasonal Influence on the Numbers of Gender-Related Orofacial Cleft Conceptions in the Netherlands.

Abstract:

BACKGROUND:In the multifactorial etiology of orofacial clefts (OFCs), environmental factors play an important role. To trace the influence of these factors, the timing of the cell biological mechanisms that occur during embryological development of the primary and secondary palates must be taken into account. That is, the fusion process of the facial and palatal processes, respectively, followed by their differentiation into bone and musculature, which take place during the first trimester of pregnancy. During this period, harmful seasonal influences such as viral infections and vitamin deficiencies could induce OFC in the embryo. AIMS:The aim of this study is to find out whether a seasonal conception period with an increased risk of OFC development exists, particularly gender related. METHODS:This was a retrospective cross-sectional study on children with OFC born in the Netherlands from 2006 to 2016. Total conception rates of live births in the Netherlands were used as a control group. χ2 tests were performed to analyze monthly and seasonal differences. Males and females, positive and negative family history and subphenotype groups based on fusion and/or differentiation (F- and/or D-) defects, and their timing in embryogenesis were analyzed separately. RESULTS:In total, 1653 children with OFC, 1041 males and 612 females, were analyzed. Only males with FD-defects showed a significant seasonal variation with an increase in conceptions during spring, most often in May. CONCLUSIONS:Males with FD-defects showed a significant seasonal variation with an increase in conceptions during spring. No other seasonal trends could be demonstrated.

authors

van der Lek LM,Pool SMW,de Jong K,Vermeij-Keers C,Mouës-Vink CM

doi

10.1177/1055665620987693

subject

Has Abstract

pub_date

2021-01-20 00:00:00

pages

1055665620987693

eissn

1055-6656

issn

1545-1569

pub_type

杂志文章
  • Development of a microportable imaging system for otoscopy and nasoendoscopy evaluations.

    abstract:OBJECTIVE:Imaging systems for patients with cleft palate typically are not portable, but are essential to obtain an audiovisual record of nasoendoscopy and otoscopy procedures. Practitioners who evaluate patients in rural, remote, or otherwise medically underserved areas are expected to obtain audiovisual recordings of...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/05-063.1

    authors: VanLue M,Cox KM,Wade JM,Tapp K,Linville R,Cosmato C,Smith T

    更新日期:2007-03-01 00:00:00

  • Birth Prevalence of Orofacial Clefts in Kuwait From Hospital-Based Registration: Retrospective Study.

    abstract:INTRODUCTION:Cleft lip and palate (CLAP) are the most common craniofacial anomalies and birth defects globally. Despite the fact that a tertiary care registry of clefts has existed in Kuwait since 2008, to date there is no published data regarding the prevalence of orofacial clefts in this population. OBJECTIVE:To tab...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1177/1055665618766059

    authors: Alhayyan WA,Pan SC,AlQatami FM

    更新日期:2018-11-01 00:00:00

  • Premaxillary osteotomy and guided tissue regeneration in secondary bone grafting in children with bilateral cleft lip and palate.

    abstract:OBJECTIVE:To introduce a surgical technique for secondary alveolar bone grafting performed in conjunction with premaxillary osteotomy and guided tissue regeneration in children with bilateral clefts. This paper also looks at the outcomes of this surgery in a series of 15 consecutive patients. METHODS:Secondary alveola...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/06-032.1

    authors: Scott JK,Webb RM,Flood TR

    更新日期:2007-09-01 00:00:00

  • Dental anomalies as part of the cleft spectrum.

    abstract:OBJECTIVE:The aim of this study was to determine subphenotypes of clefts based on tooth development. Dental phenotypes (tooth agenesis, supernumerary and impacted teeth, transposition, and structural anomalies) outside the cleft area in the permanent dentition of oral cleft individuals were investigated. DESIGN:Evalua...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/07-064.1

    authors: Menezes R,Vieira AR

    更新日期:2008-07-01 00:00:00

  • Evaluation of Postorthodontic Changes in the Treatment of Cleft Lip and Palate Patients Using the PAR Index.

    abstract:OBJECTIVE:To evaluate dental changes in cleft patients after undergoing orthodontic treatment for at least 2 years. HYPOTHESIS:The dental change would decline significantly after 2 years of completing orthodontic treatment. DESIGN:This is a retrospective study. PATIENT:Eighteen repaired cleft lip and palate patients...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1177/1055665619860038

    authors: Trimetsuntorn K,Manosudprasit A,Manosudprasit A,Phaoseree N,Pisek A,Pisek P

    更新日期:2020-01-01 00:00:00

  • Dual segmental distraction osteogenesis of the midface in a patient with Apert syndrome.

    abstract:OBJECTIVE:To present orthodontic treatment combined with dual segmental distraction osteogenesis in a patient with Apert syndrome. PATIENT:A 15-year-old boy exhibited severe midfacial hypoplasia with retruded and hypoplastic maxilla and anterior open bite. The patient was treated with a rigid external distraction II s...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/04-151.1

    authors: Takashima M,Kitai N,Murakami S,Takagi S,Hosokawa K,Kreiborg S,Takada K

    更新日期:2006-07-01 00:00:00

  • Fourier analysis of cephalometric shapes.

    abstract::Craniofacial growth and development involve both size and shape variations. Shape variations can be assessed independently from size using mathematical methods such as the Fourier series. A method for the reconstruction of outlines starting from selected landmarks and for their Fourier analysis has been developed and ...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1996_033_0206_faocs_2.3.co_2

    authors: Ferrario VF,Sforza C,Poggio CE,D'Addona A,Taroni A

    更新日期:1996-05-01 00:00:00

  • Lack of Association Between MTHFR, MTR, MTRR, and TCN2 Genes and Nonsyndromic CL±P in a Chinese Population: Case-Control Study and Meta-Analysis.

    abstract::Nonsyndromic cleft lip with or without cleft palate (NSCLP) is a common congenital deformity, often associated with folate deficiency. The genes MTHFR, MTR, MTRR, and TCN2 play key roles in folate metabolism. The risk of NSCLP associated with particular variants in the folic acid pathway differs among ethnic groups. T...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章,meta分析

    doi:10.1597/14.067

    authors: Jiang C,Yin N,Zhao Z,Wu D,Wang Y,Li H,Song T

    更新日期:2015-09-01 00:00:00

  • Neonatal Macroglossia: Demographics, Cost of Care, and Associated Comorbidities.

    abstract:OBJECTIVES:To examine the birth prevalence of congenital macroglossia and identify demographic variables and comorbidities that may influence length of stay and cost of care. STUDY DESIGN:Retrospective cross-sectional study using the Kids' Inpatient Database 2003, 2006, 2009, and 2012. METHODS:Demographics were analy...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1177/1055665618760898

    authors: Simmonds JC,Patel AK,Mildenhall NR,Mader NS,Scott AR

    更新日期:2018-09-01 00:00:00

  • Results of a survey of cleft palate teams concerning the use of nasendoscopy.

    abstract::A national survey was conducted concerning methods used for the evaluation of velopharyngeal function with emphasis on the role of nasendoscopy. Forty-five percent of questionnaires were returned. Ninety percent of the responding teams indicated that nasendoscopy was available. Sixty-one percent agreed that endoscopy ...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1993_030_0035_roasoc_2.3.co_2

    authors: D'Antonio LL,Achauer BM,Vander Kam VM

    更新日期:1993-01-01 00:00:00

  • Effects of subglottal air pressure on velopharyngeal muscle activity in dogs.

    abstract:OBJECTIVE:To analyze the effects of airflow in the larynx on activity of the levator veli palatini and pterygopharyngeal muscles. DESIGN:Ten adult beagle dogs were anesthetized with sodium pentobarbital. In each dog, two tracheal tubes were inserted subsequent to tracheotomy, one in the direction of the vocal folds an...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_2003_040_0351_eosapo_2.0.co_2

    authors: Kogo M,Iida S,Senoo H,Ishii S,Hamaguchi M,Enomoto A,Matsuya T

    更新日期:2003-07-01 00:00:00

  • Secondary Dentition Characteristics in Children With Nonsyndromic Unilateral Cleft Lip and Palate: A Retrospective Study.

    abstract:OBJECTIVE:Children with cleft lip and palate are reported to be commonly associated with higher prevalence of dental anomalies such as hypodontia, supernumeraries, and abnormalities in tooth size, shape, and position. This study investigated the prevalence of dental anomalies in a longitudinal cohort of children with u...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1177/1055665617750489

    authors: Tan ELY,Kuek MC,Wong HC,Ong SAK,Yow M

    更新日期:2018-04-01 00:00:00

  • Family environment of individuals with oral clefts in Argentina.

    abstract:OBJECTIVE:The purpose of this investigation was to study the social environment of families of children with different types of nonsyndromic oral clefts (OC) and to compare these groups with a control population of families of children without clefts. DESIGN:The study compared three nonsyndromic oral cleft groups and ...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/03-118.1

    authors: Wyszynski DF,Perandones C,Yannibelli P,Bennun RD

    更新日期:2005-03-01 00:00:00

  • Growth rate of the vomer in normal and cleft lip and palate human fetal specimens.

    abstract::The present study, part of an ongoing investigation of normal and dysmorphic development of the human fetal oronasal capsule, examined the rate of growth of the vomer. For comparative purposes, 29 human fetal specimens (20 "normal" and 9 cleft lip and palate [CLP]) were celloidin embedded, sectioned, stained with hema...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1992_029_0038_grotvi_2.3.co_2

    authors: Kimes KR,Mooney MP,Siegel MI,Todhunter JS

    更新日期:1992-01-01 00:00:00

  • Incidence of cleft lip and palate in Uganda.

    abstract:OBJECTIVE:The purpose of the study was to estimate the need for resources for cleft repairs in Uganda by determining the overall incidence of oral-facial clefts and the ratio of isolated cleft lip to isolated cleft palate to cleft lip and palate. DESIGN:A 1-year prospective study was implemented in seven hospitals and...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/09-076

    authors: Dreise M,Galiwango G,Hodges A

    更新日期:2011-03-01 00:00:00

  • Management of alveolar cleft bone grafting--state of the art.

    abstract::Bone grafting of the alveolus is an essential step in the reconstruction of the orofacial cleft deformity. Secondary grafting with iliac marrow consistently produces trabecular bone to unify the maxilla and provide odontogenic support. It requires preoperative maxillary alignment, well designed mucoperiosteal flaps, a...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章,评审

    doi:10.1597/1545-1569_2000_037_0229_moacbg_2.3.co_2

    authors: Eppley BL,Sadove AM

    更新日期:2000-05-01 00:00:00

  • Le Fort III Distraction With Internal vs External Distractors: A Cephalometric Analysis.

    abstract:OBJECTIVE:This study compares the change in midface position following Le Fort III advancement using either rigid external distraction (group 1) or internal distraction (group 2). We hypothesized that, with reference to right-facing cephalometry, internal distraction would result in increased clockwise rotation and inf...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1177/1055665617754460

    authors: Robertson KJ,Mendez BM,Bruce WJ,McDonnell BD,Chiodo MV,Patel PA

    更新日期:2018-05-01 00:00:00

  • Lateral videofluoroscopy: a modification to aid in velopharyngeal assessment and measurement.

    abstract::To overcome the difficulty of obtaining adequate videofluoroscopic images with small children because of lack of cooperation and their inability to keep their heads still and correctly rotated, a 3D View-Master was attached to the x-ray table. Its use greatly increased the ability to conduct lateral videofluoroscopies...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1994_031_0134_lvamta_2.3.co_2

    authors: Sommerlad B,Rowland N,Harland K

    更新日期:1994-03-01 00:00:00

  • Accuracy of information reported by parents and children evaluated by a cleft palate team.

    abstract::Children with palatal clefts and their parents were interviewed to determine what information they had about the cleft and its management. Their responses were compared with the standards of 17 team members from seven disciplines. Both parent and child were consistently provided information about clefts that they were...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1991_028_0329_aoirbp_2.3.co_2

    authors: Paynter ET,Edmonson TW,Jordan WJ

    更新日期:1991-10-01 00:00:00

  • Habilitation of patients with clefts: parent and child ratings of satisfaction with appearance and speech.

    abstract::This study examined ratings regarding satisfaction with facial appearance and speech performance from 495 parent-child pairs. Data were obtained from school-aged children (5-18 years old) and their parents using standardized independent interviews. Results revealed that 54 percent of the children with cleft lip (CL) o...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1992_029_0262_hopwcp_2.3.co_2

    authors: Broder HL,Smith FB,Strauss RP

    更新日期:1992-05-01 00:00:00

  • Costochondral grafts replacing the mandibular condyle.

    abstract:OBJECTIVE:The purpose of this study was to determine the success rate of costochondral bone grafts used to replace absent or nonfunctioning temporomandibular joints and the subsequent growth of these grafts when placed in young children. DESIGN:This is a retrospective study of all cases with adequate follow-up records...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1999_036_0334_cgrtmc_2.3.co_2

    authors: Ross RB

    更新日期:1999-07-01 00:00:00

  • Impact of Virtual Planning on Surgical Reposition of the Premaxilla Using an Endonasal Approach and Simultaneous Alveoloplasty.

    abstract:OBJECTIVE:Describe the surgical repositioning of the premaxilla using an innovative minimally invasive endonasal approach and secondary bone graft at the same time. We want to emphasize the importance of virtual surgical planning in this technique. MATERIAL AND METHODS:A total of 6 patients with bilateral complete cle...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1177/1055665618791706

    authors: Martínez Plaza A,Martínez EB,Tara MPP,Fernandez ABM,Iglesias FM,López AE

    更新日期:2019-04-01 00:00:00

  • Effect of placement of a speech appliance on levator veli palatini muscle activity during speech.

    abstract:OBJECTIVE:The purposes of this electromyographic study were to examine whether levator veli palatini muscle activity during speech can be changed with placement of a speech appliance and to clarify whether or not the change is related to the type of speech appliance used. DESIGN:Electromyography (EMG) was performed du...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_2000_037_0478_eopoas_2.0.co_2

    authors: Tachimura T,Nohara K,Wada T

    更新日期:2000-09-01 00:00:00

  • Sleep disturbances in 22q11.2 deletion syndrome: a case with obstructive and central sleep apnea.

    abstract::The 22q11.2 deletion syndrome is characterized by wide phenotypic variability, frequently involving characteristic craniofacial features, cardiac malformations, and learning difficulties. Skeletal anomalies are also common and include an obtuse angle of the cranial base, retrognathia, and cervical spine abnormalities....

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/05-196

    authors: Heike CL,Avellino AM,Mirza SK,Kifle Y,Perkins J,Sze R,Egbert M,Hing AV

    更新日期:2007-05-01 00:00:00

  • Use of the Sphenoid Flap in Repair of the Wide Cleft Palate.

    abstract:OBJECTIVE:In wide palatal defects, closure of the nasal layer can prove a considerable challenge. Mobilizing nasal flaps posteriorly usually facilitates soft palate closure. However, the defect is often too wide within the hard palate; hence, bilateral vomerine flaps are frequently required. Despite this, there is ofte...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1055665617732781

    authors: Khan K,Hardwicke J,Seselgyte R,Morris P,Thorburn G,Kangesu L,Swan MC,Richard B

    更新日期:2018-03-01 00:00:00

  • Changes produced by presurgical orthopedic treatment before cheiloplasty in cleft lip and palate patients.

    abstract:OBJECTIVE:The purpose of this study was to test the hypothesis that, with the use of preoperative treatment, the dimensions of the upper part of the oral cavity of an infant with unilateral cleft lip and palate (UCLP) become more similar to those of a noncleft infant. DESIGN:This was a retrospective study of upper den...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1999_036_0515_cpbpot_2.3.co_2

    authors: Kozelj V

    更新日期:1999-11-01 00:00:00

  • Measurement of health-related and oral health-related quality of life among individuals with nonsyndromic orofacial clefts: a systematic review and meta-analysis.

    abstract::Objective : To compare health-related quality of life and oral health-related quality of life between nonsyndromic individuals with and without cleft lip and/or cleft palate and to identify the most affected quality of life dimensions in individuals with cleft lip and/or palate. Design : Systematic review and meta-ana...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章,meta分析,评审

    doi:10.1597/13-104

    authors: Queiroz Herkrath AP,Herkrath FJ,Rebelo MA,Vettore MV

    更新日期:2015-03-01 00:00:00

  • Cleft lip and palate repair in Hay-Wells/ankyloblepharon-ectodermal dysplasia-clefting syndrome.

    abstract::Hay-Wells/ankyloblepharon-ectodermal dysplasia-clefting syndrome is a rare autosomal dominant disorder characterized by ankyloblepharon, ectodermal dysplasia, and cleft lip and/or cleft palate. Mutations in the p63 gene recently have been shown to be etiologic in the majority of cases of ankyloblepharon-ectodermal dys...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章,评审

    doi:10.1597/06-065

    authors: Cabiling DS,Yan AC,McDonald-McGinn DM,Zackai EH,Kirschner RE

    更新日期:2007-05-01 00:00:00

  • The Buccinator Mucomuscular Flap: An In-Depth Analysis and Evaluation of Its Role in the Management of Velopharyngeal Dysfunction.

    abstract:BACKGROUND:A significant proportion of patients with cleft palate experience persisting velopharyngeal dysfunction (VPD) after primary surgery. Pharyngoplasty is the most common procedure to correct inadequate velopharyngeal closure. Although it is often effective, it poses a risk for postoperative airway obstruction. ...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/14-283

    authors: Ahl R,Harding-Bell A,Wharton L,Jordan A,Hall P

    更新日期:2016-09-01 00:00:00

  • Management of the impaired adult cleft patient: the last chance.

    abstract:OBJECTIVE:Unfortunately, not all patients receive the benefits of a well-trained, experienced, multidisciplinary cleft team, and a significant number of patients reach adulthood with severe neglected cleft related problems. The vast majority of this group have made their way through several surgical procedures, usually...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/03-039.1

    authors: Felemovicius J,Ortiz-Monasterio F

    更新日期:2004-09-01 00:00:00