Abstract：
OBJECTIVES:To examine the birth prevalence of congenital macroglossia and identify demographic variables and comorbidities that may influence length of stay and cost of care. STUDY DESIGN:Retrospective cross-sectional study using the Kids' Inpatient Database 2003, 2006, 2009, and 2012. METHODS:Demographics were analyzed. Linear regression modeling and multivariate analyses were performed. RESULTS:The birth prevalence of congenital macroglossia was 4.63/100 000 births. Patients were classified as isolated (n = 349, 48.1%) or syndromic (n = 377, 51.9%). A higher incidence of isolated macroglossia was seen in females (odds ratio, OR [95% confidence interval, 95% CI]: 1.93 [1.45-2.56] and African Americans (2.02 [1.41-2.88]). Length of stay was higher for syndromic patients than for nonsyndromic patients (22.6 days [18.6-26.6] vs 7.93 days [5.95-9.90], as were inpatient costs ($3619USD [$27 628-$44 754] vs $10 168USD [$6272-$14 064]. After accounting for gender, race, location, and socioeconomic status, the presence of macroglossia alone increased length of stay by 4.07 days (0.42-7.72 days) in nonsyndromic patients and 12.02 days (3.63-20.4 days) in syndromic patients. The cost of care increased by $6207USD ($576-$11 838) among nonsyndromic newborns and $17 205USD ($374-34 035) among syndromic patients. CONCLUSION:The birth prevalence of congenital isolated macroglossia appears to vary by sex and race. Prolonged length of stay and increased costs are associated with both isolated macroglossia and syndromic macroglossia, even after controlling for other syndromic comorbidities.
journal_name
Cleft Palate Craniofac Jjournal_title
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Associationauthors
Simmonds JC,Patel AK,Mildenhall NR,Mader NS,Scott ARdoi
10.1177/1055665618760898subject
Has Abstractpub_date
2018-09-01 00:00:00pages
1122-1129issue
8eissn
1055-6656issn
1545-1569journal_volume
55pub_type
杂志文章abstract：OBJECTIVE:The purpose of this study was to assess the cardiac evaluation of cleft lip and/or palate patients, characterize their cardiovascular malformations, and determine the impact of cardiovascular malformations on surgical management. DESIGN:A single-institution retrospective study of 329 consecutive cleft patien...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/12-131
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to test the hypothesis that, with the use of preoperative treatment, the dimensions of the upper part of the oral cavity of an infant with unilateral cleft lip and palate (UCLP) become more similar to those of a noncleft infant. DESIGN:This was a retrospective study of upper den...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/1545-1569_1999_036_0515_cpbpot_2.3.co_2
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:Our aim was to analyze our technique of a modified rotational advancement in conjunction with buccal mucosal grafts (BMGs) in a subgroup of severe cleft cases. DESIGN:A retrospective clinical and photographic evaluation was conducted. Columella angle (CA) and tip projection (TPR) served as instruments in a p...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/16-092
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:To describe the effect of time after velopharyngoplasty on outcome and to search for preoperative prognostic factors for residual hypernasality in patients with 22q11.2 deletion syndrome. DESIGN:Retrospective chart review. SETTING:Tertiary hospital. PATIENTS:Patients with 22q11.2 deletion syndrome and velo...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/10-049
更新日期：2012-07-01 00:00:00
abstract：BACKGROUND:Mucous cysts of the nose are a rare complication of rhinoplasty. They may develop as a result of implantation or herniation of mucosa. The entrapped epithelium may proliferate, forming a subcutaneous cyst. PATIENTS AND METHODS:Two patients with unilateral cleft lip nose deformity had previously undergone co...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/08-236
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:Various causal mechanisms of familial nonsyndromic craniosynostosis have been presented. One hypothesis suggests that overproduction of bone at the suture is the primary origin of craniosynostosis, which affects brain and cranial growth secondarily through altered intracranial pressure (Primary Suture Fusion ...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/05-107
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVE:Levator veli palatini muscles from normal palates of adult humans and goats are predominantly slow oxidative (type 1) fibers. However, 85% of levator veli palatini fibers from cleft palates of adult goats are physiologically fast (type 2). This fiber composition difference between cleft and normal palates may...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/06-036.1
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:Clinical studies have shown both abnormal and normal mental and psychomotor development in patients with craniosynostosis. However, a number of confounding variables make study comparisons difficult. For these reasons, the present study describes early neuromotor development in an homogeneous rabbit model of ...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/1545-1569_2003_040_0486_enbicr_2.0.co_2
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:In wide palatal defects, closure of the nasal layer can prove a considerable challenge. Mobilizing nasal flaps posteriorly usually facilitates soft palate closure. However, the defect is often too wide within the hard palate; hence, bilateral vomerine flaps are frequently required. Despite this, there is ofte...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章,多中心研究
doi：10.1177/1055665617732781
更新日期：2018-03-01 00:00:00
abstract：:The adolescent patient provides a unique opportunity for the clinician to be both retrospective and prospective. While adolescence is a period of selective and rapid oral facial growth and dental arch development, the period of rapid speech development is long past. The adolescent patient is entering a period of quies...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章,评审
doi：10.1597/1545-1569_1995_032_0109_saoa_2.3.co_2
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVE:A meta-analysis was performed to estimate the association between maternal cigarette smoking and the risk of having a child with a nonsyndromic oral cleft (NSOC). DESIGN:Studies published from 1966 through 1996 were retrieved using MEDLINE, Current Contents, bibliographies, and other sources. MEDLINE and Cur...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章,meta分析
doi：10.1597/1545-1569_1997_034_0206_mcsaoc_2.3.co_2
更新日期：1997-05-01 00:00:00
abstract：:Objectives : We herewith report the case of a 43-year-old patient who experienced a skull base fracture associated with minimal trauma. The computed tomography scan examination showed unusual extensive pneumatization of the skull base. This patient used to perform repeated Valsalva maneuvers on a daily basis sin...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/11-280
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:Nonsyndromic cleft lip/palate (NSCLP) has the characteristics of a complex genetic trait. Linkage and association studies have suggested that one or more clefting loci may be located on chromosome 4q. The goal of this study was to evaluate the possible linkage and association due to linkage disequilibrium bet...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/03-160.1
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVES:To assess the risk of dental anomaly presentation in permanent teeth in a group of Colombian children with nonsyndromic cleft lip and palate (NSCLP) and to determine the frequency of the anomalies according to the cleft type. METHODS:An analytical matched case-control study was conducted with 210 controls a...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1177/1055665619861498
更新日期：2020-01-01 00:00:00
abstract：:Objective : The purpose of this cross-sectional study was to assess the prevalence of dental caries in children with cleft lip, alveolus, and/or cleft palate living in central Germany between 1996 and 2010. Participants : A total of 295 children 1 to 6 years of age from three birth cohorts (BC) with clefts from centra...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/12-106
更新日期：2014-05-01 00:00:00
abstract：:G.A. Ilizarov's clinical insights and experimental biology have developed into what is known today as distraction osteogenesis. Initially used for the treatment of fractures and nonunions, his methods have proven successful for limb lengthening and bone transportation. A brief history of the development of distraction...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章,评审
doi：10.1597/1545-1569_1994_031_0473_eacewd_2.3.co_2
更新日期：1994-11-01 00:00:00
abstract：OBJECTIVE:The purpose of this project was to develop objective computer-based methods to measure nasal asymmetry and abnormality in children undergoing treatment of unilateral cleft lip (UCL) and to determine the correlation of these measures to clinical expectations. PARTICIPANTS:Thirty infants with UCL undergoing cl...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/16-035
更新日期：2017-09-01 00:00:00
abstract：:The influence of the periosteum on the regeneration of palatal bone was investigated in this study. Eighty, 8-week-old, purebred beagle dogs were assigned randomly to four groups: (1) unoperated dogs as a group control; dogs in which the mid-third of the palate was surgically removed and (2) left unrepaired (unrepaire...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/1545-1569_1995_032_0228_piropd_2.3.co_2
更新日期：1995-05-01 00:00:00
abstract：:The anatomy of the greater palatine foramen has variation with regard to location, but there have been no reports on the absence of a complete foramen. We present 2 cases of pediatric patients with cleft palates possessing a greater palatine "notch" as opposed to a bony foramen. Awareness of this anomaly is advantageo...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1177/1055665618762879
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVES:Reviews of the quality of reporting of randomized controlled trials (RCTs) have recently been conducted in different surgical specialties. In this review of RCTs relating to cleft lip, cleft palate, and cleft lip and palate (CL/P), we investigate the quality of reporting against the Consolidated Standards of...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章,评审
doi：10.1597/14-267
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:To investigate whether reported parental concern is supported by hearing assessment findings in children with cleft palate. To describe this population by examining the relationship between cleft type, middle ear status, and hearing loss. DESIGN:Retrospective consecutive case note review. SETTING:Tertiary i...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1177/1055665619899743
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:We present an audit of primary cleft palate surgery at our unit, including rates of oronasal fistula development, speech outcomes, and rates of velopharyngeal insufficiency requiring secondary surgery. DESIGN:A retrospective study of patients with all cleft palate types, born between January 1990 and Decembe...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/06-205.1
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:Routine hospital admission following pharyngeal flap (PF) to correct velopharyngeal insufficiency (VPI) is the standard at most hospitals. Nevertheless, there is increasing resistance from third-party providers to approve stays longer than a "short stay" (23-hour) observation period. The purpose of the curren...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1177/1055665617732776
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:To record maxillary and mandibular displacement with articular growth and in response to bimaxillary surgical repositioning in patients with hemifacial microsomia (HFM) and to observe ipsilateral corpus/ramus growth in severely affected children. DESIGN:Prospective roentgen stereometric analysis (mean age 7 ...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/02-123.1
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:Cleft in the lip and/or the palate (CL/P) is considered to be a lifelong condition, yet relatively little is known about the long-term outcomes for patients. Existing literature is largely outdated and conflicted, with an almost exclusive focus on medical aspects and deficits. OBJECTIVE:To explore the psych...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/14-178
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:This study aims to present the pattern and management of atypical facial clefts from a Nigerian population. DESIGN:This is a retrospective study of patients seen during series of surgical outreach programs in North Central Nigeria, between 2011 and 2017. All cases of atypical facial clefts encountered were e...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1177/1055665618790884
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:To report a case of blepharo-cheilo-dontic (BCD) syndrome, to compare with the previous cases, and to discuss the possible treatment. PATIENT:The patient was a 14-day-old boy born uneventfully on August 7, 2002. His scalp hair was sparse and curly. A tumor on the top of his head, which was thought to be a de...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章,评审
doi：10.1597/04-200.1
更新日期：2006-03-01 00:00:00
abstract：:The use of a tongue flap for treatment of palatal fistulae is a well-established procedure, but it is not without complication. We report on a patient who underwent palatal fistula closure with tongue flap as a child, who then developed a nasal papilloma from the mucosa of the tongue flap 40 years later. This case is ...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/11-056
更新日期：2013-07-01 00:00:00
abstract：:A national survey was conducted concerning methods used for the evaluation of velopharyngeal function with emphasis on the role of nasendoscopy. Forty-five percent of questionnaires were returned. Ninety percent of the responding teams indicated that nasendoscopy was available. Sixty-one percent agreed that endoscopy ...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1597/1545-1569_1993_030_0035_roasoc_2.3.co_2
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:To evaluate postoperative pain, hospital length of stay (LOS), and associated costs of multiple perioperative analgesic strategies following alveolar bone grafting (ABG). DESIGN:Retrospective comparative cohort study. SETTING:Tertiary care pediatric hospital. PATIENTS/PARTICIPANTS:Iliac crest bone graft (I...
journal_title：The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
pub_type： 杂志文章
doi：10.1177/1055665618791943
更新日期：2019-04-01 00:00:00
